Choosing the right city in which to launch your startup can make or break your company. Miguel Tovar/University of Houston

Choosing the best city for your startup can mean the difference between success and closing up shop prematurely. It's important to think outside your home city for a startup launch because your home city may not have the ecosystem set up for your particular startup.

If you give in to your emotions; staying in your hometown because it's, well, your hometown, you risk preventing your company from launching in a city more conducive to its growth.

Here are three keys to making sure you choose the right city for your startup.

A city's ecosystem

Few things are more valuable to a new company than a web of like-minded companies, investors, social groups and connections. You want a city that uses its resources to grow and maintain its startups. Whether it be accelerators or pitching events or entrepreneur conferences, the city you choose needs to be active in the startup community. Establishing your startup in a city with a weak ecosystem will halt the growth of your company because it'll be that much harder to boost your company without a city's support.

A city's social network

A city with a robust social circle of like-minded entrepreneurs is a city that is doing something right for startups. First of all, if the city is rich in like-minded entrepreneurs, then that means they are living there. So there has to be a reason for that: the city is startup-friendly. Second, a city with a strong social sphere of startups means you have more opportunities to make connections and network. You can meet with other business owners to discuss issues important to your companies and even learn new things from each other. What's more is you have a chance to work with other companies to help each other grow. The city of New Orleans has Krewe de Nieux, for example. This social group is a resource for over forty technology startups in the city.

A chance to give back

Opportunities to give back. The best city for your startup will have plenty of opportunities to give back. For example, giving high school students real-life work experience to expand their knowledge and prepare them for a career in the field. A city with a plethora of opportunities like charities, youth groups, internships and career and business organizations allows startups to barter: we will give you experience and you can help us get work done. You help each other grow. In doing so, you blossom the city's startup community as a whole.

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This article originally appeared on the University of Houston's The Big Idea.

Rene Cantu is the writer and editor at UH Division of Research.

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Houston organizations launch collaborative center to boost cancer outcomes

new to HOU

Rice University's new Synthesis X Center officially launched last month to bring together experts in cancer care and chemistry.

The center was born out of what started about seven years ago as informal meetings between Rice chemist Han Xiao's research group and others from the Baylor College of Medicine’s Dan L Duncan Comprehensive Cancer Center at the Baylor College of Medicine. The level of collaboration between the two teams has grown significantly over the years, and monthly meetings now draw about 100 participants from across disciplines, fields and Houston-based organizations, according to a statement from Rice.

Researchers at the new SynthX Center will aim to turn fundamental research into clinical applications and make precision adjustments to drug properties and molecules. It will focus on improving cancer outcomes by looking at an array of factors, including prevention and detection, immunotherapies, the use of artificial intelligence to speed drug discovery and development, and several other topics.

"At Rice, we are strong on the fundamental side of research in organic chemistry, chemical biology, bioengineering and nanomaterials,” Xiao says in the statement. “Starting at the laboratory bench, we can synthesize therapeutic molecules and proteins with atom-level precision, offering immense potential for real-world applications at the bedside ... But the clinicians and fundamental researchers don’t have a lot of time to talk and to exchange ideas, so SynthX wants to serve as the bridge and help make these connections.”

SynthX plans to issue its first merit-based seed grants to teams with representatives from Baylor and Rice this month.

With this recognition from Rice, the teams from Xiao's lab and the TMC will also be able to expand and formalize their programs. They will build upon annual retreats, in which investigators can share unpublished findings, and also plan to host a national conference, the first slated for this fall titled "Synthetic Innovations Towards a Cure for Cancer.”

“I am confident that the SynthX Center will be a great resource for both students and faculty who seek to translate discoveries from fundamental chemical research into medical applications that improve people’s lives,” Thomas Killian, dean of the Wiess School of Natural Sciences, says in the release.

Rice announced that it had invested in four other research centers along with SynthX last month. The other centers include the Center for Coastal Futures and Adaptive Resilience, the Center for Environmental Studies, the Center for Latin American and Latinx Studies and the Rice Center for Nanoscale Imaging Sciences.

Earlier this year, Rice also announced its first-ever recipients of its One Small Step Grant program, funded by its Office of Innovation. The program will provide funding to faculty working on "promising projects with commercial potential," according to the website.

Houston physicist scores $15.5M grant for high-energy nuclear physics research

FUTURE OF PHYSICS

A team of Rice University physicists has been awarded a prestigious grant from the Department of Energy's Office of Nuclear Physics for their work in high-energy nuclear physics and research into a new state of matter.

The five-year $15.5 million grant will go towards Rice physics and astronomy professor Wei Li's discoveries focused on the Compact Muon Solenoid (CMS), a large, general-purpose particle physics detector built on the Large Hadron Collider (LHC) at CERN, a European organization for nuclear research in France and Switzerland. The work is "poised to revolutionize our understanding of fundamental physics," according to a statement from Rice.

Li's team will work to develop an ultra-fast silicon timing detector, known as the endcap timing layer (ETL), that will provide upgrades to the CMS detector. The ETl is expected to have a time resolution of 30 picoseconds per particle, which will allow for more precise time-of-flight particle identification.

The Rice team is collaborating with others from MIT, Oak Ridge National Lab, the University of Illinois Chicago and University of Kansas. Photo via Rice.edu

This will also help boost the performance of the High-Luminosity Large Hadron Collider (HL-LHC), which is scheduled to launch at CERN in 2029, allowing it to operate at about 10 times the luminosity than originally planned. The ETL also has applications for other colliders apart from the LHC, including the DOE’s electron-ion collider at the Brookhaven National Laboratory in Long Island, New York.

“The ETL will enable breakthrough science in the area of heavy ion collisions, allowing us to delve into the properties of a remarkable new state of matter called the quark-gluon plasma,” Li explained in a statement. “This, in turn, offers invaluable insights into the strong nuclear force that binds particles at the core of matter.”

The ETL is also expected to aid in other areas of physics, including the search for the Higgs particle and understanding the makeup of dark matter.

Li is joined on this work by co-principal investigator Frank Geurts and researchers Nicole Lewis and Mike Matveev from Rice. The team is collaborating with others from MIT, Oak Ridge National Lab, the University of Illinois Chicago and University of Kansas.

Last year, fellow Rice physicist Qimiao Si, a theoretical quantum physicist, earned the prestigious Vannevar Bush Faculty Fellowship grant. The five-year fellowship, with up to $3 million in funding, will go towards his work to establish an unconventional approach to create and control topological states of matter, which plays an important role in materials research and quantum computing.

Meanwhile, the DOE recently tapped three Houston universities to compete in its annual startup competition focused on "high-potential energy technologies,” including one team from Rice.

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This article originally ran on EnergyCapital.