Ayoade Joy Ademuyewo founded Lokum last year to create a solution to better connecting medical specialists with health care facilities nationwide. Photo courtesy of Lokum

Ayoade Joy Ademuyewo says that anesthesiology is “the coolest thing in the world.” That’s why she became a certified registered nurse anesthetist.

And that career, which she says is “the perfect blend of science and art,” led to the creation of her startup, Lokum.

Lokum App is a matchmaking engine that aims to connect Ademuyewo’s peers with jobs. She explains that before her innovation, staffing for nurse anesthetists traditionally owed to job boards 30 years older than she was or to recruitment agencies that left them at a disadvantage.

“I didn't want to use that job board because it was sort of difficult to use and I didn't want to use it and a lot of other people felt the same way,” she recalls.

When a desperate friend asked for her help navigating the terrain of finding CRNA work as an independent contractor, Ademuyewo says the wheels began turning in her mind.

“I just thought, 'Why can't I open up my phone and see all of the available jobs to me, based on my preferences and my skills? And I can easily select from them to go to my next job.' And that's sort of where the questions started. And I just kept asking those questions. And I think about two or three years into asking the questions I was like, 'Oh my gosh, I think I'm starting a company,'” Ademuyewo says.

In the hours that she wasn’t in surgery, the CRNA began doing market research.

“As I was studying the market, and mapping it out, these really complex mind maps started to happen. And it was almost a natural conclusion that the more you understand the problem, the more the solution starts to appear to you,” she explains.

And she saw that the obvious solution was also potentially a big opportunity for her to create something entirely new — neither a job board nor an agency, but something entirely new. Ademuyewo calls Lokum a “matchmaking engine.” It takes the preferences, specialties and skills of CRNAs like her and matches them to jobs that make sense for them. To date, the pilot has connected users with around 200 hospitals and clinics in 20 states.

Fortunately, because there are so few CRNAs in practice, they are a unified bunch.

“It’s a really well-networked profession,” says Ademuyewo. “ I'm lucky to be in a profession where what we do is really special and really specialized.”

Because she was already part of the tight knit community, the founder had no trouble finding pilot customers. She worked with Houston-based Octaria Software to engineer the technical side of the app, as well as another local cybersecurity firm to work on infrastructure.

Lots of big news has come for Ademuyewo in the first half of 2024. She participated in this year’s cohort of the Google for Startups Accelerator Program-North America, which she says helped to gain traction in her fundraising amid a bear market.

The result? Early this month, Lokum announced a raise of $700,000 in pre-seed funding, which will be allocated to improving and enhancing the existing technology. Those funds came from Houston investors including Aileen Allen, of the Houston Angel Network, Mercury, and The Artemis Fund; and Matt Miller, former Liongard product executive, as well as from Houston-based VC firm South Loop Ventures. More came from the non-local JP Morgan and Techstars.

Today, Ademuyewo is devoted full-time to Lokum, though she still practices her favorite combination of science and art on weekends in order to maintain her licensure.

“I will always be clinical, that will never change,” she says. “Part of that is just staying close to the problem and the people who are experiencing it, I think that is exactly the right thing for me to be doing.”

Rice Business Plan Competition named its participants for 2024. Photo courtesy of Rice

Annual student startup competition in Houston names teams for 2024

ready to pitch

The Rice Alliance for Technology and Entrepreneurship announced the 42 student-led teams worldwide that will compete in the highly competitive Rice Business Plan Competition this spring.

The annual competition, known as one of the world’s largest and richest intercollegiate student startup competitions, will take place April 4 to 6 in Houston. Teams in this year's competition represent 35 universities from four countries, including two teams from Houston and four others from Texas.

Teams, made up of graduate students from a college or university anywhere in the world, will present their plans before 350 angel, venture capital, and corporate investors to compete for more than $1 million in prizes. Last year, teams were awarded $3.4 million in investment and in-kind prizes, the largest total awarded thus far in the decades-old competition after some investors doubled — or even tripled — down on investment awards.

The 2024 RBPC will focus on five categories: Energy, Cleantech and Sustainability; Hard Tech; Life Sciences and Healthcare Solutions; Digital Enterprise; Consumer Products and Services.

Invitees include:

  • AIRS ML, Imperial College London (United Kingdom)
  • Blaze Power, UCLA
  • ChiChi Foods, Washington University in St. Louis
  • CureWave Sciences, Rutgers University
  • CurveAssure, Johns Hopkins University
  • D.Sole, Carnegie Mellon University
  • Dendritic Health AI, Northwestern University
  • Dialysis Innovations, University of Michigan
  • FlowCellutions, University of Pittsburgh
  • HEXAspec, Rice University
  • HydroPhos Solutions, University of New Hampshire
  • Icorium Engineering Company, University of Kansas
  • Informuta, Tulane University
  • Kiwi Charge, York University (Canada)
  • Korion Health, University of Maryland, College Park
  • Limitless Aeronautics, Embry Riddle Aeronautical University
  • LiQuidium, University of Houston
  • Malleous, University of Pittsburgh
  • MesaQuantum, Harvard University
  • MineMe, University of Pennsylvania
  • NaviAI, Cornell University
  • NutriAI, Tufts University
  • OSPHIM, RWTH Aachen University (Germany)
  • Overture Games, Northwestern University
  • OX SOX, University of Georgia
  • Oxylus Energy, Yale University
  • Palanquin Power, University of Texas at Austin
  • Paradigm Robotics, University of Texas at Austin
  • Particle-N, University of Connecticut
  • Poka Labs, Harvard University
  • Power2Polymer, RWTH Aachen University (Germany)
  • ProPika, University of Arkansas
  • Protein Pints, Michigan State University
  • Samtracs, Oklahoma State University
  • Sancorda Medical, University of Texas at Dallas
  • Side Coach Sports, Baylor University
  • Socian AI, Rochester Institute of Technology
  • Somnair, Johns Hopkins University
  • TouchStone, University of California, Berkeley
  • Vita Innovations, Stanford University
  • WattShift, University of Chicago
  • ZebraMD, UCLA

The companies join more than 700 RBPC alumns that have collectively raised more than $5.5 billion in funding. More than 269 RBPC companies are in business or have made successful exits, according to the Rice Alliance's website.

Last year, Texas A&M-based team FluxWorks took home $350,000 and won the competition based on judges scores. The company's technology includes magnetic gears that are four times quieter than standard with 99 percent efficiency.

Sygne Solutions and TierraClimate, two Rice-led teams, won second and fourth places, respectively. Zaymo, from Brigham Young University, took home the most in investment dollars. Click here to see the full list of 2023 teams.

Put in the effort to create a strong people culture from the start — it can make all the difference for your company. Photo by Tom Werner/Getty Images

Houston expert: How to build a strong people culture from day one

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Entrepreneurs are driven and tenacious when building a business. However, the laser focus on making a business profitable, from logistics to taxes and everything in between, can sometimes cause one important element to be missed, the people.

The best business plans cannot work without people to implement the details. When a strong people culture is established from the very beginning, the employees who help build the company from the ground up, stay engaged and can become an integral part of the company’s success for years to come.

Below are a few items to help entrepreneurs concentrate on their most precious asset, their people, pinpoint their motivations and learn how employees can enjoy what they do every day, which can take any business to the next level.

Share values

The onus falls on the business leaders within a startup to create a work environment that encourages employees to succeed and enjoy their career. Nurturing a culture rooted in a shared mission and values allows the company to easily build a desirable workplace where employees are eager to return.

When communicating a company’s values, they are more influential when they are lived by leadership. For example, if curiosity is a key value, leadership should encourage teams to ask questions and not be afraid to try to speak up when there may be a more effective path for the business.

It is also important for business owners to look for candidates to fill roles in the growing business who embody their key values. This may mean looking beyond the job description for like-minded people who align with the values and who then bring a positive outlook to the position, are more apt to collaborate and are fully engaged.

Offer unique benefits

Small businesses have the upper hand when it comes to unique benefits because they are a much nimbler organization. When an organization intentionally creates a people-first environment, there is near immediate access to leadership, rapid advancement opportunities are more plentiful and the impact employees at every level can have on the organization is monumental. This is an exciting prospect for so many who share an entrepreneur’s vision.

There are also the traditional benefits that are essential to a strong people culture. This may seem like a daunting prospect, but it can be simple to provide employees, while also competing with large-company benefits, with the help of a professional employer organization. What will strengthen a people culture’s foundation is offering the traditional benefits along with the benefits many enjoyed during the pandemic, which may have been cut by other organizations, such as mental health programs, expanded sick-leave, financial wellness programs, care benefits and others.

When deciding what benefits to offer, it is important to ask employees what benefits mean the most to them. Every benefit may not be feasible, but employees having a say in their benefits further strengthens the people culture.

Communicate

It sounds simple but establishing a culture with transparent communication, within reason, is conducive to a strong people culture. However, for many entrepreneurs, communicating without a plan often leads to not communicating at all.

Set the stage for clear, consistent communication from the very beginning. For example, establishing a standing meeting, whether it is once per week or every morning, allows leadership to share updates, make announcements and point out team wins. For employees, it is an open forum to ask questions. Also setting the standard to talk to employees before making any major policy changes builds trust in the organization, even if the policy change may not be the most desirable for everyone. By surveying staff before a policy change, leadership can clearly communicate the reasoning and have a fully prepared team before implementation.

In a growing business, it is easy to put your head down and grind forward, but engaged employees are essential to making an entrepreneur’s dream come to fruition. Putting in the effort to create a strong people culture from the start will help ensure you have employees who want to be a part of the organization and contribute to its success.

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Jill Chapman is a director of early talent programs with Insperity, a leading provider of human resources and business performance solutions.
After working with thousands of interns, Allie Danziger of Ampersand Professionals says she's now got a product to upskill and train new hires for employers. Photo courtesy of Ampersand

Houston startup rolls out B2B program for onboarding new hires

job training

After seeing success with her internship training and matchmaking platform, Allie Danziger, founder and CEO of Ampersand Professionals, has expanded the concept to include a new hire training service that allows employers to better optimize the onboarding process and have a well-trained new staff member from day one.

In just over a year, Ampersand has worked with over 7,000 professionals through its original concept of upskilling and matching young professionals to internship programs. A few months ago, Danziger and her team expanded to include career development training for students first entering the workforce with the City of Houston's Hire Houston Youth program. Danziger says it was developing out the platform for this program that proved there was a need for this type of training.

"While we have focused on matching professionals with businesses for paid internships, we recognized a further gap with employers that have their own recruiting/talent acquisition teams, or just their own preferred way of bringing on entry-level talent, and didn’t have a need for our matching platform," Danziger tells InnovationMap. "But, they recognized the benefit of our proven training platform that pre-vets and de-risks their hires, and still wanted access to the training for their own hires."

The new program has evolved from training interns to new hires, so parts of the program that focuses on interviewing or applying for a job have been removed. Instead, the 8.5 hours of training focuses on networking, best practices for working with a manager and team, performance reviews, common software training, and more.

Danziger says usually new hires need the most experienced mentor or manager, but they don't usually get that support — especially when it comes to businesses that don't have their own built-out mentorship or training program.

"Ampersand’s new training product fills that gap — it gives employers of any size any easy solution to provide basic job readiness training to employees, access to our team of dedicated coaches, and a detailed report at the end of their training summarizing how their new hire did in the training and any trends recognized and tips for managing this employee based on what the platform uncovered," she says. "Businesses can also sign up for additional coaching sessions and customize training materials, as an add-on if interested."

The program costs the employer $100 per new employee, and checkout online takes less than a minute. Through both this program and the original internship program, Ampersand is constantly evolving its training content.

"These professionals are going through the same training experience that we have proven out over the last year, and we are constantly adding to based on data we see in the user experience," Danziger says.

Danziger recently joined the Houston Innovators Podcast discuss some of the benchmarks she's met with Ampersand, as well as the importance of investing in Gen Z hires. Listen to that episode below.


SeekerPitch exists to update the job hiring process in a way that benefits both the job seekers and recruiters. Photo via Getty Images

Houston startup shakes up antiquated hiring process for the next generation

new way to hire

Companies across the country have been requiring resumes and cover letters from their new hire hopefuls since the World War II era, and it's about time that changed. A startup founded in Houston has risen to the occasion.

Houstonian Samantha Hepler had the idea for SeekerPitch when she was looking for her next move. She felt like she had developed a formidable career in digital transformation and had worked with big name clients from Chevron to Gucci. However, she couldn't even get an interview for a role she felt she would be a shoe-in for.

"I knew if I could just get through the door, a company would see the value in me," Hepler tells InnovationMap. "I wasn't being seen, and I wasn't being heard. I didn't know a way to do that."

And she wasn't alone in this frustration. Hepler says she discovered she was one of the 76 percent of job candidates who get filtered out based on former job titles and keywords. At the same time, Hepler says she discovered that 80 percent of companies reported difficulty finding talent.

Samantha Hepler had the idea for SeekerPitch based on her own ill-fated job hunt experience. Photo courtesy of SeekerPitch

"I was just a symptom of a larger problem companies were facing," Hepler says. "Companies were using algorithms to dilute their talent pool, and then the hires they were making weren't quality because they were looking for people based on what they've done. They weren't looking at people for what they could do."

SeekerPitch, which is in the current cohort of gBETA Houston, allows job seekers to create an account and tell their story — not just their job history. The platform prioritizes video content and quick interviews so that potential hires can get face-to-face with hiring managers.

"We empower companies to hear the candidates' stories," Hepler says. "We're bringing candidates streaming to computer screens. We are the Netflix of recruiting."

Hepler gives an example of a first-generation college graduate who's got "administrative assistant" and "hostess" on her resume — but who has accomplished so much more than that. She put herself through school with no debt and in three years instead of four. SeekerPitch allows for these types of life accomplishments and soft skills into the recruiting process.

SeekerPitch profiles allow job seekers to tell their story — not just their past job experience. Photo courtesy of SeekerPitch

Over the past few years, a trend in hiring has been in equity and diversity, and Hepler says that people have been trying to address this with blurring out people's names and photos.

"Our belief is that connection is the antidote to bias," Hepler says, mentioning a hypothetical job candidate who worked at Walmart because they couldn't afford to take multiple unpaid internships. "They can't come alive on a resume and they won't stand a chance next to another person."

SeekerPitch is always free for job seekers, and, through the end of the year, it's also free for companies posting job positions. Beginning in January 2022, it will cost $10 per day to list a job opening. Also next year — Hepler says she'll be opening a round of pre-seed funding in order to grow her team. So far, the company has been bootstrapped, thanks to re-appropriated funding from Hepler's canceled wedding. (She opted for a cheaper ceremony instead.)

Right now, SeekerPitch sees an opportunity to support growing startups that need to make key hires — and quickly. The company has an ongoing pilot partnership with a Houston startup that is looking to hiring over a dozen positions in a month.

"As a startup, your key hires are going to make or break your company — but you have to hire quickly," Hepler says. "That's the ultimate challenge for startups. ... But if you don't hire well it can cost your company a lot of money or be the demise of your company. It's people who make a company great."

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Houston innovator's new platform empowers wealth building for underserved communities

houston innovators podcast episode 269

For Phillip Yates, this year will be the year of launch. The attorney-turned-entrepreneur has been working on his fintech platform, Equiliberty, for years now, but come the first half of 2025, it's go time.

"We're going to release our technology in Q2 of this year, and we're looking to commercialize it by the end of this year," Yates says on the Houston Innovators Podcast.



The platform connects users with resources to build wealth. Yates, along with his co-founders, Rachel Howard and Cody Bailey, created the company with the mindset that people with lower financial means can take control of their own financial success — in a way that doesn't take away from anyone else.

"Really, (this year is) about how can we move into other markets that have seen what we can do if you celebrate culture, celebrate community, celebrate our differences — and more importantly give opportunities to be wealth builders. You can do this without taking from anyone else."

For years, Equiliberty has worked on convening the community in Houston. Yates, who's also the chairman of social impact innovation organization Impact Hub Houston, spearheaded Black Entrepreneurs Week and Latin Entrepreneurs Week — with more in the works.

"We are a fintech platform, and by convening the ecosystem, we are able to use data to tell the story to those financial institutions that want to get in front of their customers," he says. "All of these are bridges for those who may be unseen and overlooked to have a way into the economy ... and to have access to capital and resources they need to build wealth."

Yates shares on the show how he's evolved his legal career as a corporate and bankruptcy lawyer to entrepreneurship. Last fall, Yates won the award for Ecosystem Builder at the Houston Innovation Awards, an achievement he says validates his career to date.

"You can be a good doer in the world and have a heart that wants to solve a problem, but if you don't have the true experience or the resources to be able to invest in someone, I'm not saying you will be a disservice, but it might be counterintuitive," he says. "Through my experience as a lawyer, it's allowed me to be a greater service."

Houston tech company tapped by NASA for near space initiative

3, 2, 1...

Houston-based space exploration, infrastructure, and services company Intuitive Machines has nailed down a NASA deal to expand the agency’s communications network for spacecraft.

Additionally, NASA recently completed the first round of “human in the loop” testing for Intuitive Machines’ Moon RACER lunar terrain vehicle at the agency’s Johnson Space Center. RACER (Reusable Autonomous Crewed Exploration Rover) is one of three commercially developed unpressurized lunar terrain vehicles being considered for NASA’s Artemis lunar initiative.

Intuitive Machines is among four companies awarded contracts for NASA’s Near Space Network, enabling transmission of data from space to the earth. The network supports NASA missions such as the International Space Station and Hubble Space Telescope. It also will play a role in NASA’s Artemis initiative, which aims to send astronauts to the moon.

Under the initial Near Space Network contracts, project timelines run from February 2205 to September 2029. A five-year option would extend the contracts through September 2034. Collectively, the contracts are worth $4.82 billion.

Intuitive Machines received two contracts for services that will ease communications demand on NASA’s Deep Space Network and “meet the mission requirements for unique, highly elliptical orbits,” says NASA.

“We are privileged to help NASA deliver essential data and transmission services that support missions navigating the critical pathways between [the earth and the moon], and beyond,” Intuitive Machines CEO Steve Altemus says in a news release.

In September, NASA awarded Intuitive Machines a contract for development of a constellation of lunar data satellites.

Meanwhile, conclusion of “human in the loop” testing puts Intuitive Machines one step closer to its Moon RACER vehicle being chosen for the Artemis lunar initiative. Vehicles from two other companies are in the running. The winning vehicle is scheduled to be announced in 2025.

“Human in the loop” testing enables NASA astronauts to provide feedback on the lunar vehicles’ functionality, safety, and design.

The Moon RACER, featuring a rechargeable electric battery and a robotic arm, is designed to accommodate two astronauts and 882 pounds of cargo. Furthermore, it is supposed to pull a trailer loaded with 1,764 pounds of cargo.

14 Houston startups start 2025 with fresh funding

recent vc activity

Houston startups wrapped up the last few months of 2024 with big funding news — from several seeds and series As to series C rounds and extensions.

Here are 14 Houston startups that secured funding in the the last four months of last year, according to reporting by InnovationMap.

Citroniq Chemicals secures $12M series A (September)

Houston-based Citroniq Chemicals has secured its series A funding. Photo via Getty Images

A fresh $12 million round of funding will enable Houston-based Citroniq Chemicals to propel planning, design, and construction of its first decarbonization plant.

An unidentified multinational energy technology company led the series A round, with participation from Houston-based Lummus Technology Ventures and cooperation from the State of Nebraska. The Citroniq plant, which will produce green polypropylene, will be located in Nebraska.

“Lummus’ latest investment in Citroniq builds on this progress and strengthens our partnership, working together to lower carbon emissions in the plastics industry,” Leon de Bruyn, president and CEO of Lummus Technology, says in a news release. Read more.

MetOx raises $25M series B extension (September)

A Houston company has raised funding. Photo via Getty Images

A Houston company has closed its series B extension at $25 million.

MetOx International, which develops and manufactures high-temperature superconducting (HTS) wire, announced it closed a $25 million series B extension. Centaurus Capital, an energy-focused family office, and New System Ventures, a climate and energy transition-focused venture firm, led the round with participation from other investors.

"MetOx has developed a robust and highly scalable operation, and we are thrilled to partner with the Company as it enters this pivotal growth stage," says John Arnold, founder of Centaurus, in a news release. "The market for HTS is expanding at an unprecedented pace, with demand for HTS far outweighing supply. MetOx is poised to be the leading U.S. HTS producer, closing the supply gap and bringing dramatic capacity to high power innovations and applications. Their progress and potential are unmatched in the field, and we are proud to support their growth." Read more.

Utility Global's $53M series C investment (September)

Utility Global’s technology enables reduction of greenhouse gas emissions along with generation of low-carbon fuels and chemicals. Photo courtesy of Utility Global

Houston-based Utility Global, a maker of decarbonization-focused gas production technology, has raised $53 million in an ongoing series C round.

Among the participants in the round are Canada’s Ontario Power Generation Pension Plan, the XCarb Innovation Fund operated by Luxembourg-based steel company ArcelorMittal, Houston-based investment firm Ara Partners, and Saudi Aramco’s investment arm. Read more.

Bot Auto's $20M pre-series A (October)

The Investment is expected to help expand Bot Auto's tech development in autonomous trucking that will focus on safety and operation efficiency. Photo courtesy of Bot Auto

A Houston-based autonomous vehicle technology company has raised early funding.

Bot Auto has announced the completion of its pre-series A funding round which was oversubscribed and raised $20 million. The round was led by investments from Brightway Future Capital, Cherubic Ventures, EnvisionX Capital, First Star Ventures, Linear Capital, M31 Capital, Taihill Venture, Uphonest Capital, and Welight Capital.

“As true believers in autonomous trucking, we're thankful for our investors' shared vision,” Xiaodi Hou, founder and CEO of Bot Auto, says in a news release. “Our strong commitment, combined with recent AI advancements and a sharpened focus on operational efficiency, has created a clear path to commercialization.” Read more.

Mstack raises $40M series A (October)

Shreyans Chopra, founder of Mstack, is celebrating the close of his company's $40 million series A. Photo courtesy of Mstack

Houston-based Mstack, whose platform helps manufacturers source specialty chemicals, has raised $40 million in a series A funding round.

Lightspeed Venture Partners and Alpha Wave Incubation led the round, which includes a debt facility from HSBC Innovation Banking and money from several angel investors.

In a news release, Mstack says the infusion of cash will enable it to “double down on its mission to disrupt a historically flawed supply chain for specialty chemicals.” Read more.

DocJuris raises $8M series A (October)

DocJuris has raised a $8 million series A. Photo via Getty Images

Houston-based DocJuris, a leader in AI contract review, announced the successful closure of its series A funding round by raising $8 million in new capital. This brings the total capital raised to date to $11.2 million.

"DocJuris AI has become an industry-leading platform that empowers enterprise legal, procurement, and sales teams to close deals faster while reducing risk," DocJuris CEO and Founder Henal Patel says in a news release. "With this funding, we will continue scaffolding our platform around generative AI, expand our customer success team, and grow our user base." Read more.

Paladin lands $5.2M in seed funding (October)

Paladin’s AI-enhanced autonomous drones help public safety agencies, such as police and fire departments, respond to 911 calls. Photo via paladindrones.io

Houston-based Paladin, whose remotely controlled drones help first responders react quickly to emergencies, has collected $5.2 million in seed funding.

Gradient, a seed fund that backs AI-oriented startups, led the round. Also participating were Toyota Ventures, the early-stage VC arm of Japanese automaker Toyota; venture capital firm Khosla Ventures; and VC fund 1517.

“We believe Paladin will drive meaningful change in public safety and redefine how communities are served,” Gradient said in an announcement about the seed round. Read more.

March Biosciences' oversubscribed $28.4M series A (October)

March Biosciences' oversubscribed raise brought in $28.4 million of financing with Mission BioCapital and 4BIO Capital leading the pack of investors. Photo via Getty Images

An emerging biotech company in Houston has closed its series A with outsized success.

March Biosciences' oversubscribed raise brought in $28.4 million of financing with Mission BioCapital and 4BIO Capital leading the pack of investors. The company has now raised more than $51 million in total.

Last year, March Biosciences announced its strategic alliance with CTMC (Cell Therapy Manufacturing Center), a joint venture between MD Anderson Cancer Center and National Resilience. CEO Sarah Hein met her co-founder, Max Mamonkin, at the TMC Accelerator for Cancer Therapeutics. Along with fellow co-founder Malcolm Brenner, March Biosciences launched from the Center for Cell and Gene Therapy (Baylor College of Medicine, Houston Methodist Hospital and Texas Children’s Hospital). Its goal is to fight cancers that have been unresponsive to existing immunotherapies using its lead asset, MB-105. Read more.

CrossBridge Bio closes $10M seed round (November)

CrossBridge Bio, formed during the TMC Innovation’s Accelerator for Cancer Therapeutics program, closed a $10 million seed round led by TMC Venture Fund and CE-Ventures. Photo via Getty Images

A Houston biotech company based off research out of UTHealth Houston has raised seed funding to continue developing its cancer-fighting therapeutic.

CrossBridge Bio, formed during the TMC Innovation’s Accelerator for Cancer Therapeutics program, closed a $10 million seed round led by TMC Venture Fund and Crescent Enterprises' VC arm, CE-Ventures. The round also included participation from Portal Innovations, Alexandria Venture Investments, Linden Lake Labs, and several pre-seed investors.

“We are thrilled to have the support of such experienced investors who share our vision of bringing transformative cancer therapies to patients in need,” Michael Torres, CEO of CrossBridge Bio, says in a news release. Torres served as an entrepreneur in residence of ACT. Read more.

Helix Earth closes $5.6M in seed funding (November)

Helix Earth's technology is estimated to save up to half of the net energy used in commercial air conditioning, reducing both emissions and costs for operators. Photo via Getty Images

A Houston startup with clean tech originating out of NASA has secured millions in funding.

Helix Earth Technologies closed an oversubscribed $5.6 million seed funding led by Houston-based research and investment firm Veriten. Anthropocene Ventures, Semilla Capital, and others including individual investors also participated in the round.

“This investment will empower the Helix Earth team to accelerate the development and deployment of our first groundbreaking hardware technology designed to disrupt a significant portion of the commercial air conditioning market, an industry that is ready for innovation,” Rawand Rasheed, Helix Earth co-founder and CEO, says in a news release. Read more.

Fervo Energy's $255M in additional funding (December)

The deal brings Fervo's total funding secured this year to around $600 million. Photo courtesy of Fervo

A Houston company that's responding to rising energy demand by harnessing geothermal energy through its technology has again secured millions in funding. The deal brings Fervo's total funding secured this year to around $600 million.

Fervo Energy announced that it has raised $255 million in new funding and capital availability. The $135 million corporate equity round was led by Capricorn’s Technology Impact Fund II with participating investors including Breakthrough Energy Ventures, CalSTRS, Congruent Ventures, CPP Investments, DCVC, Devon Energy, Galvanize Climate Solutions, Liberty Mutual Investments, Mercuria, and Sabanci Climate Ventures.

Additionally, Fervo secured a $120 million letter of credit and term loan facility from Mercuria, an independent energy and commodity group that previously invested in the company.

The funding will go toward supporting Fervo's ongoing and future geothermal projects. Read more.

Square Robot closes series B after year of growth (December)

The advanced submersible robotics company will put the funds toward international expansion. Photo courtesy of Square Robot

Houston- and Boston-based Square Robot Inc. closed a series B round of funding last month.

The advanced submersible robotics company raised $13 million, according to Tracxn.com, and says it will put the funds toward international expansion.

"This Series B round, our largest to date, enables us to accelerate our growth plans and meet the surging global demand for our services,” David Lamont, CEO, said in a statement. Read more.

Indapta Therapeutics secures $22.5M (December)

Houston- and Seattle-based Indapta Therapeutics has fresh funding to grow its cancer-fighting cell therapy. Photo via Getty Images

A promising cell therapy company has raised its latest funding round — to the tune of $22.5 million.

Indapta Therapeutics, which has a dual headquarters in Houston and Seattle, is a clinical stage biotechnology and next-generation cell therapy company focused on the treatment of cancer and autoimmune diseases. The company announced it has closed a $22.5 million round of new financing to accelerate the clinical development of its differentiated allogeneic Natural Killer cell therapy.

"This funding will enable us to generate significant additional data in our ongoing trial of IDP-023 in cancer as well as initial data from our first trial in autoimmune disease," Mark Frohlich, Indapta’s CEO, says in a news release. Read more.

SmartAC.com's latest round (December)

Houston-based Mercury backed SmartAC.com in a follow-on round. Photo via of SmartAC.com

Houston-based SmartAC.com, which provides a customer loyalty management platform for contractors, has raised a follow-on round from Mercury Fund and other investors. The dollar amount of the round wasn’t disclosed.

An October filing with the U.S. Securities and Exchange Commission (SEC) indicates SmartAC.com planned to raise $8.2 million in venture capital. Of that sum, about $4 million had already been raised, the company reported, and nearly $4.2 million remained to be raised.

SmartAC.com's platform enables contractors in the HVAC and plumbing industries monitor, manage, and optimize their maintenance memberships through advanced sensors, AI-driven diagnostics, and proactive alerts. Read more.