These five Houston startups are linking up industries and blockchain technology. Getty Images

Blockchain has really started to come into its own as more and more companies are applying the technology across industries — from oil and gas analytics and fundraising to even social media marketing.

Five Houston companies have made their mark on these different industries by incorporating this burgeoning technology.

Data Gumbo

Andrew Bruce had the idea for Data Gumbo when he realized how difficult it was to share data in upstream oil and gas. Courtesy of Data Gumbo

As the blockchain-as-a-service company's name suggests, Houston-based Data Gumbo is all about the data.

"The whole idea is to build out the blockchain network, and provide a network that they can subscribe to and start doing business on that network," Andrew Bruce, CEO of Data Gumbo, says. "It's a service, so there's a subscription fee. It gives them access to the savings they already have available within their organizations."

The company, which focuses on providing midstream and upstream oil and gas companies with timely decision-making information, was launched in 2016 and faced a big learning curve in the industry.

"We got a lot of questions and concerns about what blockchain is, why they need it, and whether or not they can trust it," Bruce says. "We were introducing a completely new concept to a conservative industry."

The industry is coming around as Data Gumbo grows its network and proves results.

Social Chains

Big companies are using your data to make a profit — but what if you got a kickback of that cash? That's what Houston-based Social Chains is trying to do. Pexels

When it comes to social media marketing, Houston-based Social Chains is putting the power back into the hands of users. Big social media companies, like Facebook, sell data about you to marketers and advertisers, and there's nothing you can do about it. Social Chains is a new platform where users own their own data and receive a cut of the payment.

"On our platform, the user is a stakeholder. Our platform distributes 50 percent of the profits to the users," Srini Katta, founder and CEO of the company, says.

Social Chains already has 5,000 users and, Katta says, that's with little to no marketing efforts. Currently, he's been working out a few kinks before launching into marketing for the platform, though he expects to do that beginning next month. Most of Social Chain's current users are high school to college students, so that will be the primary demographic for the marketing strategy.

Topl

Houston-based Topl can track almost anything using its blockchain technology. Courtesy of Topl

Blockchain, when applied to consumer products, can be used to complete the full picture of that product. A chocolate bar, for instance, can be traced from cacao farm to grocery store. Not only does the connected information keep each party accountable when it comes to prices, it tells a story.

"We are a generation that wants a story," says Kim Raath, CFO of Topl. "We want an origin, and don't want to be fooled. And, because you might be able to reduce the cost by having this transparency, you might be able to bring down the cost on both sides."

Topl, a Houston-based startup that was created by a few Rice University graduate and doctorate students, uses blockchain to connect the dots. One of the ways Topl's technology is being used is to track money. If an investor gives to a fund, and the fund gives to a startup, there's nothing to connect that first investor to the startup's success or to measure its impact. This is a tool used by investors or donors alike. For instance, if you were to create a scholarship, you can use Topl to track what student received that money and if they are meeting the required metrics for success.

Topl's 2019 focus is on growing its network and what it's able to provide its clients, like an app factory for companies trying to track specific things.

Iownit.us

The stock market has been using tech for years — why shouldn't the private sector have the same convenience? Getty Images

To Rashad Kurbanov, the private investment world was extremely backwards. While the stock market had been digitizing investment for years, private funds had a drawn out process of emails and meetings before moves were made. He thought introducing technology into the process could help simplify the investing for both sides of the equation.

"What we do, and where technology helps us, is we can take the entire process of receiving interest from investors, signing the transactions, issuing the subscription agreements, and processing the payments and put that all online," says Kurbanov, CEO and co-founder of Houston-based iownit.us.

The company is still seeking regulatory approval, but once that happens, the technology and platform will be ready to launch. The platform is a digital site that connects investors to companies seeking money. The investors can review the companies and contribute all online while being encrypted and protected by blockchain.

Houston Blockchain Alliance

blockchain

Here are some of the most common, misunderstood aspects about blockchain technology. Getty Images

The Houston Blockchain Alliance is a newly formed networking group for anyone working within or interested in the blockchain industry. Mahesh Sashital, co-founder of Smarterum, a blockchain news site, founded the organization late last year after realizing Houston was in need of an informative networking group.

"I thought that I'd start the Houston Blockchain Alliance so that someone like me, who's already in the industry, can find other people working in the industry," he says. "And for other people interested in blockchain can learn more and get up to speed with the technology."

The alliance aims to host regular events — its launch event is Feb. 20 — and educate people on blockchain. Click here to read Sashital's guest column about common blockchain misunderstandings.


Tech startups are popping up across industries from real estate to oil and gas, and these three founders are among the leaders in technology. Courtesy images

3 Houston tech innovators to know this week

Who's who

Often, technology and innovation are mistaken for each other. While not mutually exclusive, both tech and innovation work well together in Houston across all industries — from oil and gas to real estate and social media. These three founders engaged technology for their individual startups.

Srini Katta, founder and CEO of Social Chains

Courtesy of Social Chains

As a social media user, your data is already out there and being used for marketing purposes. But, rather than the Facebooks or Googles of the world making a profit, Srini Katta wanted to create a platform where users made a profit off their own data.

"On our platform, the user is a stakeholder. Our platform distributes 50 percent of the profits to the users," he says.

Social Chains already has 5,000 users and, Katta says, that's with little to no marketing efforts, which Katta is about to launch.

Martin Kay, founder and CEO of Entera Technology

Courtesy of Entera

Martin Kay, who splits his time between Houston and the Bay Area for his startup Entera Technologies, knew there had to be a better way for people searching for a home to buy. He drew a comparison between homebuyers and Netflix viewers to create Entera's software.

"We're a little bit like Netflix," he says. "They go out and get content from everyone, and they begin to watch your behavior. So, Netflix has 2,000 profiles and you probably fit five or six of those. We have almost 100 profiles and what we do is say, we're going to understand what you want, watch your behavior and instead of giving you 40,000 properties on a big map, we actually match you based on your preferences, to the five or six houses that are best for you."

Houston-based Entera has grown as the platform loads more and more data for its users to engage with.

Luther Birdzell, CEO and founder of OAG Analytics

Courtesy of OAG Analytics

Luther Birdzell always knew he wanted to run his own company, but the software and analytics professional worked in various industries before realizing that oil and gas had a huge opportunity for savings using analytics. He founded OAG Analytics in 2013 to help provide a solution for these companies.

"When I founded OAG Analytics, our mission then — and still is today — was to build a platform for the upstream oil and gas industry that enables them to manage their data, introduces world-class machine learning in minutes without having to write a single line of code, and allow them to run simulations on the resulting analysis," Birdzell says.

The company has grown to 25 employees and tripled its revenue last year. The team is forecasting another year of high grow for 2019.


Big companies are using your data to make a profit — but what if you got a kickback of that cash? That's what Houston-based Social Chains is trying to do. Pexels

Houston startup aims to flip the script on social media marketing

anti social media

Social media companies are using user data for their own financial gain, but what if users had a cut in the profits? That's the business model for Houston-based Social Chains.

"Social Chains is a social media platform of real people, real privacy, and real rewards," says Srini Katta, founder and CEO of the company. "We're fixing three problems in the social media industry."

The first problem is that user data has market value, but only the Facebook, Google, and other platforms are reaping the rewards, not the user, who's the backbone of the platform. User privacy and a growing number of fake accounts are the other issues Social Chains addresses. Katta says he realized that most importantly, users should own their data

"On our platform, the user is a stakeholder. Our platform distributes 50 percent of the profits to the users," he says.

User privacy is protected and encrypted on this new platform, and users must register with a government-issued identification. Social Chains prevents fake accounts by using facial recognition.

The biggest differentiating factor of this platform is that users make real money, but it's kept track by the site's token system, which uses blockchain technology, and users receive some of the so-called "S tokens" just for signing up. And, businesses only pay for the ads that users engage with. For instance, for a marketing email, businesses will only pay for the emails that were actually opened. It's a win-win situation, as the user receives a kickback whenever they open a marketing email or engage with ads.

Social Chains already has 5,000 users and, Katta says, that's with little to no marketing efforts. Currently, he's been working out a few kinks before launching into marketing for the platform, though he expects to do that beginning next month. Most of Social Chain's current users are high school to college students, so that will be the primary demographic for the marketing strategy.

Katta says he first encountered some of the challenges using social media marketing at one of his former startups when attempting to use Facebook ads to grow the company. He says he saw increased engagement, but not as significant of an increase in sign ups on his company page.

"We looked back to see who are the people clicking on the ads," he says. "We looked at their profiles, and they were not from the United States, even though we had given geographic preferences."

He found out that third party ad management platforms were working with Facebook and click farms all around the world to increase engagement results. Katta starting thinking of a solution for this marketing problem.

"Then, in 2016, with the rise of 'fake news,' we realized this was a bigger problem," he says.

In addition to user growth, Katta hopes to grow his investors, and the company is seeking funds for its seed round in 2019.

"To be honest, we need $100 million to build this out, so we're trying to raise money," Katta says. "Personally, I've put in $3.5 million before I took any money from investors. I have a lot of skin in the game."

Currently, Social Chains has three team members, with a fourth joining soon. Diane Yoo, who is a founding member and director of the Rice Angel Network, leads growth and investor relations for the company. One obstacle for the team has been being spread out from Houston to The Woodlands and even Austin.

"I've lived in New York and San Francisco. I moved to Houston because I wanted a quiet place to raise my family," Katta says. "The biggest challenge for Houston, compared to other cities, is other cities are so dense. Houston is so sprawling. It's really hard to network, and meet potential employees."

One of the crucial connectors for Katta has been Station Houston. The team plans on meeting to work together two days a week at Station. In addition to being a great workspace, the area acts as a good hub for potential partnerships for Social Chains. Startups need marketing, of course.

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Houston digital health platform Koda lands strategic investment

money moves

Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.

New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”