These five Houston startups are linking up industries and blockchain technology. Getty Images

Blockchain has really started to come into its own as more and more companies are applying the technology across industries — from oil and gas analytics and fundraising to even social media marketing.

Five Houston companies have made their mark on these different industries by incorporating this burgeoning technology.

Data Gumbo

Andrew Bruce had the idea for Data Gumbo when he realized how difficult it was to share data in upstream oil and gas. Courtesy of Data Gumbo

As the blockchain-as-a-service company's name suggests, Houston-based Data Gumbo is all about the data.

"The whole idea is to build out the blockchain network, and provide a network that they can subscribe to and start doing business on that network," Andrew Bruce, CEO of Data Gumbo, says. "It's a service, so there's a subscription fee. It gives them access to the savings they already have available within their organizations."

The company, which focuses on providing midstream and upstream oil and gas companies with timely decision-making information, was launched in 2016 and faced a big learning curve in the industry.

"We got a lot of questions and concerns about what blockchain is, why they need it, and whether or not they can trust it," Bruce says. "We were introducing a completely new concept to a conservative industry."

The industry is coming around as Data Gumbo grows its network and proves results.

Social Chains

Big companies are using your data to make a profit — but what if you got a kickback of that cash? That's what Houston-based Social Chains is trying to do. Pexels

When it comes to social media marketing, Houston-based Social Chains is putting the power back into the hands of users. Big social media companies, like Facebook, sell data about you to marketers and advertisers, and there's nothing you can do about it. Social Chains is a new platform where users own their own data and receive a cut of the payment.

"On our platform, the user is a stakeholder. Our platform distributes 50 percent of the profits to the users," Srini Katta, founder and CEO of the company, says.

Social Chains already has 5,000 users and, Katta says, that's with little to no marketing efforts. Currently, he's been working out a few kinks before launching into marketing for the platform, though he expects to do that beginning next month. Most of Social Chain's current users are high school to college students, so that will be the primary demographic for the marketing strategy.

Topl

Houston-based Topl can track almost anything using its blockchain technology. Courtesy of Topl

Blockchain, when applied to consumer products, can be used to complete the full picture of that product. A chocolate bar, for instance, can be traced from cacao farm to grocery store. Not only does the connected information keep each party accountable when it comes to prices, it tells a story.

"We are a generation that wants a story," says Kim Raath, CFO of Topl. "We want an origin, and don't want to be fooled. And, because you might be able to reduce the cost by having this transparency, you might be able to bring down the cost on both sides."

Topl, a Houston-based startup that was created by a few Rice University graduate and doctorate students, uses blockchain to connect the dots. One of the ways Topl's technology is being used is to track money. If an investor gives to a fund, and the fund gives to a startup, there's nothing to connect that first investor to the startup's success or to measure its impact. This is a tool used by investors or donors alike. For instance, if you were to create a scholarship, you can use Topl to track what student received that money and if they are meeting the required metrics for success.

Topl's 2019 focus is on growing its network and what it's able to provide its clients, like an app factory for companies trying to track specific things.

Iownit.us

The stock market has been using tech for years — why shouldn't the private sector have the same convenience? Getty Images

To Rashad Kurbanov, the private investment world was extremely backwards. While the stock market had been digitizing investment for years, private funds had a drawn out process of emails and meetings before moves were made. He thought introducing technology into the process could help simplify the investing for both sides of the equation.

"What we do, and where technology helps us, is we can take the entire process of receiving interest from investors, signing the transactions, issuing the subscription agreements, and processing the payments and put that all online," says Kurbanov, CEO and co-founder of Houston-based iownit.us.

The company is still seeking regulatory approval, but once that happens, the technology and platform will be ready to launch. The platform is a digital site that connects investors to companies seeking money. The investors can review the companies and contribute all online while being encrypted and protected by blockchain.

Houston Blockchain Alliance

blockchain

Here are some of the most common, misunderstood aspects about blockchain technology. Getty Images

The Houston Blockchain Alliance is a newly formed networking group for anyone working within or interested in the blockchain industry. Mahesh Sashital, co-founder of Smarterum, a blockchain news site, founded the organization late last year after realizing Houston was in need of an informative networking group.

"I thought that I'd start the Houston Blockchain Alliance so that someone like me, who's already in the industry, can find other people working in the industry," he says. "And for other people interested in blockchain can learn more and get up to speed with the technology."

The alliance aims to host regular events — its launch event is Feb. 20 — and educate people on blockchain. Click here to read Sashital's guest column about common blockchain misunderstandings.


Tech startups are popping up across industries from real estate to oil and gas, and these three founders are among the leaders in technology. Courtesy images

3 Houston tech innovators to know this week

Who's who

Often, technology and innovation are mistaken for each other. While not mutually exclusive, both tech and innovation work well together in Houston across all industries — from oil and gas to real estate and social media. These three founders engaged technology for their individual startups.

Srini Katta, founder and CEO of Social Chains

Courtesy of Social Chains

As a social media user, your data is already out there and being used for marketing purposes. But, rather than the Facebooks or Googles of the world making a profit, Srini Katta wanted to create a platform where users made a profit off their own data.

"On our platform, the user is a stakeholder. Our platform distributes 50 percent of the profits to the users," he says.

Social Chains already has 5,000 users and, Katta says, that's with little to no marketing efforts, which Katta is about to launch.

Martin Kay, founder and CEO of Entera Technology

Courtesy of Entera

Martin Kay, who splits his time between Houston and the Bay Area for his startup Entera Technologies, knew there had to be a better way for people searching for a home to buy. He drew a comparison between homebuyers and Netflix viewers to create Entera's software.

"We're a little bit like Netflix," he says. "They go out and get content from everyone, and they begin to watch your behavior. So, Netflix has 2,000 profiles and you probably fit five or six of those. We have almost 100 profiles and what we do is say, we're going to understand what you want, watch your behavior and instead of giving you 40,000 properties on a big map, we actually match you based on your preferences, to the five or six houses that are best for you."

Houston-based Entera has grown as the platform loads more and more data for its users to engage with.

Luther Birdzell, CEO and founder of OAG Analytics

Courtesy of OAG Analytics

Luther Birdzell always knew he wanted to run his own company, but the software and analytics professional worked in various industries before realizing that oil and gas had a huge opportunity for savings using analytics. He founded OAG Analytics in 2013 to help provide a solution for these companies.

"When I founded OAG Analytics, our mission then — and still is today — was to build a platform for the upstream oil and gas industry that enables them to manage their data, introduces world-class machine learning in minutes without having to write a single line of code, and allow them to run simulations on the resulting analysis," Birdzell says.

The company has grown to 25 employees and tripled its revenue last year. The team is forecasting another year of high grow for 2019.


Big companies are using your data to make a profit — but what if you got a kickback of that cash? That's what Houston-based Social Chains is trying to do. Pexels

Houston startup aims to flip the script on social media marketing

anti social media

Social media companies are using user data for their own financial gain, but what if users had a cut in the profits? That's the business model for Houston-based Social Chains.

"Social Chains is a social media platform of real people, real privacy, and real rewards," says Srini Katta, founder and CEO of the company. "We're fixing three problems in the social media industry."

The first problem is that user data has market value, but only the Facebook, Google, and other platforms are reaping the rewards, not the user, who's the backbone of the platform. User privacy and a growing number of fake accounts are the other issues Social Chains addresses. Katta says he realized that most importantly, users should own their data

"On our platform, the user is a stakeholder. Our platform distributes 50 percent of the profits to the users," he says.

User privacy is protected and encrypted on this new platform, and users must register with a government-issued identification. Social Chains prevents fake accounts by using facial recognition.

The biggest differentiating factor of this platform is that users make real money, but it's kept track by the site's token system, which uses blockchain technology, and users receive some of the so-called "S tokens" just for signing up. And, businesses only pay for the ads that users engage with. For instance, for a marketing email, businesses will only pay for the emails that were actually opened. It's a win-win situation, as the user receives a kickback whenever they open a marketing email or engage with ads.

Social Chains already has 5,000 users and, Katta says, that's with little to no marketing efforts. Currently, he's been working out a few kinks before launching into marketing for the platform, though he expects to do that beginning next month. Most of Social Chain's current users are high school to college students, so that will be the primary demographic for the marketing strategy.

Katta says he first encountered some of the challenges using social media marketing at one of his former startups when attempting to use Facebook ads to grow the company. He says he saw increased engagement, but not as significant of an increase in sign ups on his company page.

"We looked back to see who are the people clicking on the ads," he says. "We looked at their profiles, and they were not from the United States, even though we had given geographic preferences."

He found out that third party ad management platforms were working with Facebook and click farms all around the world to increase engagement results. Katta starting thinking of a solution for this marketing problem.

"Then, in 2016, with the rise of 'fake news,' we realized this was a bigger problem," he says.

In addition to user growth, Katta hopes to grow his investors, and the company is seeking funds for its seed round in 2019.

"To be honest, we need $100 million to build this out, so we're trying to raise money," Katta says. "Personally, I've put in $3.5 million before I took any money from investors. I have a lot of skin in the game."

Currently, Social Chains has three team members, with a fourth joining soon. Diane Yoo, who is a founding member and director of the Rice Angel Network, leads growth and investor relations for the company. One obstacle for the team has been being spread out from Houston to The Woodlands and even Austin.

"I've lived in New York and San Francisco. I moved to Houston because I wanted a quiet place to raise my family," Katta says. "The biggest challenge for Houston, compared to other cities, is other cities are so dense. Houston is so sprawling. It's really hard to network, and meet potential employees."

One of the crucial connectors for Katta has been Station Houston. The team plans on meeting to work together two days a week at Station. In addition to being a great workspace, the area acts as a good hub for potential partnerships for Social Chains. Startups need marketing, of course.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."