Growing Houston-based WizeHire tripled its headcount last year and plans to grow even more as it scales up. Photo courtesy of WizeHire

A Houston software company has closed its latest funding round to the tune of $30 million.

WizeHire, a tech-enabled hiring solution for small businesses, announced the closing of its series B round, bringing its total funding to $37.5 million and its valuation to $250 million, according to the news release. The round was led by Tiger Global with participation from prior Houston-based investors Amplo and Mercury.

The pandemic has greatly impacted businesses ability to hire new employees. Founded in 2014, WizeHire launched a free version of its optimized hiring solution at the height of COVID-19. The company also helped small businesses find and apply for refundable tax credits and Payment Protection Program loans to keep their doors open.

“The pandemic was an incredibly tough time for Main Street, and we were right there with them," says Sid Upadhyay, CEO of WizeHire, in the release. "We’re constantly amazed by the depth of our clients’ trust in us and in response, have stepped up to serve them as a trusted advisor in their business growth. We plan to build a marketplace for small businesses to have access to the resources they need to succeed.”

Now, WizeHire is scaling its abilities to provide more resources to its customers, including offerings like tax, payroll, and insurance advice. The company also recently launched a mobile app for business owners to managing hiring on the go. Additionally, WizeHire has plans to expand into new industries — like automotive, hospitality, insurance, and home services — and add features like recommended background checks, and legally-approved offer letters, per the release.

"WizeHire has created a solution that serves and anticipates the most important needs of Main Street businesses with a focus on hiring skilled workers," Sam Harland, partner at Tiger Global, says in the release. "Rapid adoption of the WizeHire platform by small businesses illustrates the market’s potential, and we are excited to partner with Sid and the WizeHire team.”

The company, which raised its series A a little over a year ago, now has more than 15,000 employers use the platform — and 90 percent of those businesses plan to return for future hiring needs, the release states. Last year, WizeHire doubled its customer base and internally tripled its headcount. The business has plans to continue growing its team this year.

Choice Hotels has a new partner in Houston-based WizeHire. Photo courtesy of Choice Hotels

International hotel chain taps Houston staffing startup to get teams back to work

SAAS moves

A Houston startup has struck a deal with a major new client focused on getting employees back to work at its 6,000 locations worldwide.

Maryland-based international hotelier Choice Hotels International Inc. selected Houston-based WizeHire into its Qualified Vendor program as its only current recruiting solution for the thousands of franchised locations under the Choice Hotels umbrella. WizeHire provides its clients tech-enabled, customized hiring solutions and has a suite of software available for users to utilize.

"We're so excited to support Choice's independently-owned hotels with the most personal and complex part of their businesses—hiring great talent," says Sid Upadhyay, WizeHire's co-founder and CEO, in a press release.

According to data from the U.S. Bureau of Labor Statistics, the hospitality industry saw an unemployment rate of 13.5 percent. With travel expected to increase this year, Choice Hotels is looking to provide its franchisees opportunities to efficiently rehire.

"As a long-time Choice Hotels owner and WizeHire customer, I'm thrilled for what this partnership means for growing my business," says Tushar Patel, owner of Quality Inn & Suites Round Rock - Austin North, in the release.

Hospitality represents one of the six industry verticals WizeHire has listed on its website, and the startup provides "job templates created with industry experts, built-in pre-screening tools specifically for hospitality jobs and benchmarks that help identify the soft skills needed for numerous hotel roles," according to the release.

Choice Hotels nationwide will have access to these resources effective immediately, per the release.

"At a time when there is so much uncertainty for many individuals and employers in the hospitality industry, WizeHire has the opportunity to meet hiring needs at this critical moment," says Justin Nimergood, head of franchise sales for WizeHire. "I'm thrilled to be leading that charge."

After a tumultuous year in which hiring across industries essentially came to a halt, WizeHire is seeing immense business growth as companies plan to rehire, says Upadhyay in a recent interview with InnovationMap. The company recently raised a $7.5 million series A round to gear up for this growth.

With all the uncertainty last, Upadhyay says he and his team instead focused on providing resources, such as PPP loan guidance, for small businesses — something the company is focused on continuing.

"We're really going beyond just the hire," Upadhyay says in a recent episode of the Houston Innovators Podcast. "We're getting to this role where we're going to help you grow your business."

Listen to Upadhyay on the Houston Innovators Podcast:

WizeHire CEO Sid Upadhyay joins the Houston Innovators Podcast to share his big plans for his company as it gears up for growth. Photo courtesy of WizeHire

Houston startup plans to expand to revolutionize tech-enabled small business support

HOUSTON INNOVATORS PODCAST EPISODE 74

Hiring and recruiting has been a challenging and inefficient process for small businesses — yet it could not be more important as a company with a small, growing team.

"Today, whether you're running a startup for the first or second time, at the end of the day, you're just wearing too many hats," says Sid Upadhyay, co-founder and CEO of WizeHire, on this week's episode of the Houston Innovators Podcast. "Recruiting is one of those things where we know talent is the lifeblood of our businesses, but we just don't have the time to think about the process."

Upadhyay says his company, Houston-based WizeHire, lives and breathes for small businesses, and in 2014 the company launched to tap into technology to provide a software service that can streamline a more effective way for startups and small businesses to hire — and hire optimally.

Last month, the company — founded by Upadhyay, Nick Carneiro, and Jay Niblick — closed a $7.5 million series A funding round that was led by Houston-based Mercury Fund and Amplo, which is based just north of Houston in Spring. Additional support came from existing backers Ruchit Shah and RigUp co-founder Sandeep Jain. The fresh funding will go toward expansion — both of its team as well as WizeHire's products.

Upadhyay says the the effects of the pandemic — which includes many businesses ceasing to hire — had profound repercussions on WizeHire.

"We saw half our revenue disappear overnight," Upadhyay says. "As we were going through that up-and-down roller coaster, it was one of the most humbling experience."

Upadhyay says WizeHire has a close relationship with its customers, and they were reaching out asking for guidance from WizeHire during the uncertain times. Upadhyay's team took the opportunity to provide low or no-cost support, especially when it comes to navigating the CARES Act.

"We started to educate our customers about everything from PPP loans to tax credits," Upadhyay says. "We went so far as to connect 300 of our customers to banks — otherwise they wouldn't have been able to get these loans."

These efforts are what led WizeHire to its first venture capital raise. The bootstrapped company has a client base that includes more than 7,000 businesses, and the company recorded $4.7 million in run rate in 2020. Now, in light of the impact WizeHire was able to make with its clients during the pandemic, Upadhyay says the company is going to expand to include other key services, like identifying tax credits.

"We're really going beyond just the hire," Upadhyay says. "We're getting to this role where we're going to help you grow your business."

Upadhyay discusses more about WizeHire's plans for 2021 and the intentionality of the business on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


This week's roundup of Houston innovators includes Rachel Moctron of ClassPass, Sid Upadhyay of WizeHire, and Ashley Small of Medley Inc. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three innovators across industries recently making headlines — from fitness tech and software to PR and communications.

Rachel Moncton, vice president of Global Marketing at ClassPass

Rachel Moncton shares why ClassPass tapped Houston as a prime place to expand. Photo courtesy of ClassPass

ClassPass recently announced its entrance into the Houston market, and at the helm of the company's new local presence is Rachel Moncton. In a guest article for InnovationMap, she shares why ClassPass was so interested in Houston. The search actually started four years ago, but the tech company finally landed in Houston for its fourth location.

"In 2017, the ClassPass team spent nine months conducting an intensive nationwide search for a city that matched our mission and values," Moncton writes. "As a brand focused on supporting an active lifestyle, we wanted a city that offered a connection to the outdoors. One of the most important driving factors in our search was finding a city where we could attract incredible talent to our team. Though we settled on Missoula, Houston was high on the list." Click here to read more.

Sid Upadhyay, co-founder and CEO of WizeHire

A Houston startup has closed a $7.5 million round of funding with mostly local investment. Photo courtesy of WizeHire

Sid Upadhyay's startup has something to celebrate. The software company founded in Houston closed a $7.5 million series A round of funding led by two Houston-area venture capital firms — Amplo and Mercury Fund. According to a news release, WizeHire will use the funds to scale their business, which is centered around providing personalized hiring resources to small businesses.

"We're a small business helping small businesses with a team of people looking out for you," says Upadhyay. "Hiring is complex and personal. Our customers see what we do not just as software; they see us as a trusted advisor." Click here to read more.

Ashley Small, founder and CEO of Medley Inc.

From events to online shopping — here are four tech trends to look out for this year according to Ashley Small. Photo courtesy of Medley

For Ashley Small, founder and CEO of Medley Inc., innovation and inclusion go hand in hand. Business leaders need diverse voices at the table to drive new ideas and innovation.

"Innovation is actually impossible without diversity," Small says on the most recent episode of the Houston Innovators Podcast. "A part of this is also being really open minded to the fact that you are going to hear ideas that sound and look different. Be open to that, because that is 100 percent the point."

Small discusses more about how she's honoring Black History Month with her team and the evolution the PR and media industries have seen over the past decade on the episode. Click here to stream the episode and read more.

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Houston digital health platform Koda lands strategic investment

money moves

Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.

New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”