3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Moji Karimi of Cemvita Factory, Shanna Jin of Rice University, and Trent Crow of Real Simple Energy. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — data science, consumer tech, and medical device innovation — recently making headlines in Houston innovation.

Moji Karimi, co-founder and CEO of Cemvita Factory

Moji Karimi joins the Houston Innovators Podcast to discuss how his technology is offering energy execs an innovative way to meat their climate change pledge goals. Photo courtesy of Cemvita

A lot of startups are working on technology that makes existing practices more efficient, cheaper, or faster — or all of the above. But Cemvita Factory, founded by siblings Moji and Tara Karimi, is doing something that's never been done before: biomimicking photosynthesis to convert carbon emissions into useful chemicals.

"There weren't biotech companies working with oil and gas companies for this use case that we have now," Moji Karimi says on this week's episode of the Houston Innovators Podcast. "We're defining this new category for application of synthetic biology in heavy industries for decarbonization."

With this uncharted territory comes unique challenges and opportunities. Click here to read more and stream the episode.

Shanna Jin, communications and marketing specialist of the Data to Knowledge Lab at Rice University

Startups and small businesses are accumulating data daily — here's how to use that to your advantage, according to this Houston expert. Photo via rice.edu

Ironically, the power of data management is almost incalculable. With the right practices and processes in place, businesses can make better decisions and grow more strategically. But, it's not something a lot of startups or small businesses look at regularly. That's where the Rice University Data To Knowledge group comes into play.

"Being able to interpret data and making data-driven decisions becomes the key to the success of a business," writes Shanna Jin in a guest column for InnovationMap. "It is not just a privilege for big companies anymore. Small businesses need it more than ever to make sustainable growth in the digital era." Click here to read more.

Trent Crow, founder and president of Real Simple Energy

Trent Crow, founder and president, and the Real Simple Energy team have moved over to Arcardia with the acquisition. Photo courtesy of Real Simple Energy

Earlier this month, a Houston startup exited to a larger tech company. Trent Crow, co-founder and CEO of Real Simply Energy, says all eight of the company's employees have moved over to Arcadia and more workers will be hired soon. The company has maintained a mix of office and remote workers. Arcadia will look for Houston office space later this year, Crow says.

"Expansion plans include doing more of what we're doing now and offering more features for customers," says Crow, who now is Arcadia's general manager of energy services in Texas. Click here to read more.

Startups and small businesses are accumulating data daily — here's how to use that to your advantage. Photo via Getty Images

Houston expert: How to use the power of data and analytics to inform ​small businesses​

Guest column

Starting a business in a digital era brings entrepreneurs unprecedented advantages with technology and tools designed to optimize a business' operation. Whether it is a B2C or B2B, business owners can gather almost any data and metrics to improve their performance.

Being able to interpret data and making data-driven decisions becomes the key to the success of a business. It is not just a privilege for big companies anymore. Small businesses need it more than ever to make sustainable growth in the digital era.

The challenge? There are countless analytic tools and resources available that can generate data, but you need people who can extract insights from the massive amount of data.

Hire a data science team vs. outsourcing

Many companies go to campus recruitment and scout bright data science talent who also identify with their business value. Hiring people with data science and analytic skills is optimal, but for startups that are not ready to hire an in-house team or have a short-term question, outsourcing is a better option.

Data science consulting

Many online resources can help you extract data, but you are probably wondering: where do I begin? Which tool should I use? Which exact metric should I track?

The Rice University's Data Science Consulting Clinic provides free, open to the public assistance to help clients with all of those questions. It can be for various business sectors, such as research and product development, cost predictions, analytic tools, acquisition decisions, and talent management.

Here are some of the data science aspects we specialize in:

Research & Development - Obtain data to inform a decision on what products to develop.
Data analysis of who your customers are, what they are interested in, and what product to develop is crucial for B2C and B2B. A recent example of how Rice's Data Science Consulting Clinic is making a difference is a client needed assistance with market research to help inform a startup on what kind of product they should create next. The client was able to use the data resources suggested by the student and faculty consultants to gauge consumer sentiment and examples of successful products. With the data collected, the client was able to identify the features that drive customers to purchase similar products.

Cost Predictions - A case study for an energy company
Businesses need to make crucial decisions to achieve business intelligence. CEOs and managers need to base their decisions on predictions and analysis. Another client from the Data Science Consulting Clinic was interested in predicting cost and analysis of the factors contributing to the most expense for the coming year. The client's main problem was to transform the data into a statistical model that could predict the cost. With the prediction model suggested by the student consultants, the client was able to reduce the cost by controlling factors that were likely to cause higher costs.

Acquisition Decision Making for Business Professionals
Clients from the Rice MBA program were interested in investigating the causes and effects of private equity (PE) acquisition. Specifically, the clients wanted to analyze the difference in practice habits before and after acquisitions. As a result of the consultation, the clients were able to determine what factors influenced the PE's decision to acquire new equity.

Longer term projects

It would be helpful to have a dedicated data science team who can work over a semester or year long to find the solution.

Higher education has placed a prominent focus on data science programs, especially capstone projects that provide students with real-world experience. As a business owner, you might not even think about working with an esteemed university to help you with data challenges.

The Center for Transforming Data to Knowledge, informally known as the D2K Lab at Rice University, is founded based on the mission to seek real-world data challenges for passionate data science students. Student teams have worked on over 50 sponsored data science projects with partners from a wide variety of businesses, organizations, and community partners.

Advance data science and security

The perk of working with Rice University is that it provides the most advanced data science research tools and an interdisciplinary pool of student and faculty talent who are passionate about data science. Working with Rice University also guarantees a strong data security system and a comprehensive confidentiality agreement.

  • A cloud-based financial company sponsored a series of capstone projects on applying deep learning to reduce documentation errors and increase efficiency for businesses.
  • A fintech company sponsored multiple capstone projects on building statistical models to predict costs.
  • In the tech-med industry, the D2K Lab has partnered with the Medical Informational Corps, and researchers from Texas Children's Hospital and Baylor College of Medicine to build algorithms to predict cardiac events.

The future of data-driven decision making

The digital era has become the norm for all businesses (large or small), and there's no way to avoid the power of transforming data into actionable insights. So start gathering data even before you build out a business and incorporate the culture of data-driven decision making into every sector of your business.

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Shanna Jin is the communications and marketing specialist of the Data to Knowledge Lab at Rice University.

The Rice D2K Lab wants to help startups and small businesses solve business concerns with data science. Photo courtesy of Rice University

Rice University's data-focused lab presents unique opportunity for startups and small businesses

data to knowlege

A data-focused lab at Rice University is training the next generation of data scientists. However, the students at the Rice D2K Lab are doing more than just learning about the significance of data, machine learning, and artificial intelligence — they're working as data scientists now.

Businesses — large and small — can come into the lab and have Rice students and faculty work on data projects in both short-term and long-term capacity. One semester, a group of students worked with 311 call data for the city of Houston so that officials can figure out what parts of town were in the most need of support, says Jennifer Sanders, program administrator at the Rice D2K lab.

"They were able to show on a Houston map the areas where most of these 311 calls were coming from," Sanders tells InnovationMap. "That allowed the city to focus on those areas."

Lately, the lab has been focused on a several COVID-19 Houston Response Projects, which addressed issues ranging from homelessness in the time of a pandemic, ventilator distribution, and more. One team even made a recommendation to the city after a data project determined that adding five ambulances to southwest neighborhoods served by the Houston Fire Department Emergency Medical Services program would optimize response times.

The lab has two avenues to help businesses: a semester-long capstone course and a clinic for one-time sessions. This upcoming semester, the capstone course has 60 students signed up to work on 10 to 12 projects from corporate sponsors. These lab members — which support the program monetarily — are selected based on their fit within the program.

The D2K Consulting Clinic also offers free one-hour sessions on campus. At the clinic, students look at the data and assess the possibilities and advise on how to use that data for business gain or growth.

"The consulting clinic can be a starting point if a business is not sure what to do with their data," says Shanna Jin, communications and marketing specialist at the D2K Lab.

The clinic also presents a special opportunity for small businesses and startups, a niche Sanders says they haven't tapped into enough yet. She says most of the companies they've worked with are larger organizations, usually in the energy industry.

"We really want to broaden the scope to smaller startups, tech companies, and nonprofits," Sanders says. "We really don't have to limit ourselves. I would really love to expand our reach."

Membership dues for companies, which provides a more structured, long-term access to data consulting, range from $25,000 to $75,000 a year. However, Sanders says the lab is willing to work with startups on a cost that's more accessible.

Ultimately, the goal of the program is to connect the dots for businesses that have data and don't know how to use it.

"To realize the potential of big data, we need people — people who can transform data to knowledge," says the lab's founder, Genevera Allen, in a promotional video. "That's what we're doing with the Rice D2K Lab."

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CPRIT hires MD Anderson official as chief cancer prevention officer

new hire

The Austin-based Cancer Prevention and Research Institute of Texas, which provides funding for cancer research across the state, has hired Ruth Rechis as its chief prevention officer. She comes to CPRIT from Houston’s University of Texas MD Anderson Cancer Center, where she led the Cancer Prevention and Control Platform.

Before joining MD Anderson, Rechis was a member of the executive leadership team at the Livestrong Foundation, an Austin-based nonprofit that supports people affected by cancer.

“Ruth has widespread connections throughout the cancer prevention community, both in Texas and across the nation,” CPRIT CEO Kristen Doyle said in a news release. “She is a long-term passionate supporter of CPRIT, and she is very familiar with our process, programs, and commitment to transparency. Ruth is a terrific addition to the team here at CPRIT.”

Rechis said that by collaborating with researchers, policymakers, public health leaders and community partners, CPRIT “can continue to drive forward proven prevention strategies that improve health outcomes, lower long-term costs, and create healthier futures for all.”

At MD Anderson, Rechis and her team worked with more than 100 organizations in Texas to bolster cancer prevention initiatives at clinics and community-based organizations.

Rechis is a longtime survivor of Hodgkin lymphoma, a type of cancer that affects the lymph nodes, which are part of a person’s immune system.

6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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Former NASA astronaut, official joins Venus Aerospace board

astronaut appointment

Retired Air Force colonel and former NASA astronaut Pamela Melroy, who previously served as deputy administrator of NASA, recently joined the board of directors at Houston-based Venus Aerospace.

Venus Aerospace, a startup founded in 2020, develops rocket engine technology, including rotating rocket detonation engines for hypersonic flights. These engines promise higher power, greater fuel efficiency and lower emissions than conventional rocket engines or jet engines, according to the Interesting Engineering website. The global rocket propulsion market is expected to grow from $9.5 billion in 2025 to $29.9 billion by 2034, according to a forecast by ResearchAndMarkets.com.

“Advanced rocket propulsion has been of interest to me for over a decade, and Venus Aerospace’s recent achievements in demonstrating the stability of rotating detonation rocket engines represent a significant development,” says Melroy, who left NASA earlier this year and is now a self-employed consultant living in Arlington, Virginia.

Melroy, a member of the United States Astronaut Hall of Fame, has built an illustrious career in the aerospace sector. Aside from being a NASA official, she was:

  • One of only two female astronauts to command a space shuttle mission
  • Deputy program manager of Orion space exploration initiatives at aerospace and defense contractor Lockheed Martin
  • Senior technical adviser and director of field operations for the Federal Aviation Administration’s Office of Commercial Space Transportation, where she came up with the first safety guidelines for commercial human spaceflight
  • Deputy director of the Tactical Technology Office at the Defense Advanced Research Projects Agency (DARPA).
  • An adviser for the establishment of the Australian Space Agency

Venus Aerospace said in a news release that as a leader at three federal agencies, “Melroy shaped America’s strategy in space, accelerated commercial space partnerships, and deepened space exploration.”

Sassie Duggleby, co-founder and CEO of Venus Aerospace, called Melroy “a preeminent leader in the world of aerospace.”

In May, Venus Aerospace completed the inaugural test flight of its rotating detonation rocket engine. The startup, whose headquarters is at the Houston Spaceport, says it’s the only company in the world that has manufactured a flight-proven, high-thrust rotating detonation rocket engine.

On the horizon for Venus Aerospace is production of Stargazer M4, a high-speed aircraft capable of two-hour global travel.

Venus Aerospace’s investors include Airbus Ventures, America’s Frontier Fund, Trousdale Ventures, and Prime Movers Lab. The startup also gets support from the Air Force Research Laboratory (AFWERX), the Air Force, NASA and DARPA.

Jordan Blashek, co-founder and managing partner of America’s Frontier Fund, which backs startups creating breakthrough technologies, said his firm’s investment in Venus Aerospace “underscores our focus on supporting American companies that are revolutionizing industries of the future.”

“With recent hypersonic advancements from China and Russia, safeguarding American innovation and securing our industrial base has never been more urgent,” Blashek added. “Venus Aerospace is poised to redefine hypersonic flight and ensure America’s continued leadership in aerospace innovation.”

Since its founding, Venus Aerospace has raised $78.3 million in investments, according to PitchBook data.

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