3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Moji Karimi of Cemvita Factory, Shanna Jin of Rice University, and Trent Crow of Real Simple Energy. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — data science, consumer tech, and medical device innovation — recently making headlines in Houston innovation.

Moji Karimi, co-founder and CEO of Cemvita Factory

Moji Karimi joins the Houston Innovators Podcast to discuss how his technology is offering energy execs an innovative way to meat their climate change pledge goals. Photo courtesy of Cemvita

A lot of startups are working on technology that makes existing practices more efficient, cheaper, or faster — or all of the above. But Cemvita Factory, founded by siblings Moji and Tara Karimi, is doing something that's never been done before: biomimicking photosynthesis to convert carbon emissions into useful chemicals.

"There weren't biotech companies working with oil and gas companies for this use case that we have now," Moji Karimi says on this week's episode of the Houston Innovators Podcast. "We're defining this new category for application of synthetic biology in heavy industries for decarbonization."

With this uncharted territory comes unique challenges and opportunities. Click here to read more and stream the episode.

Shanna Jin, communications and marketing specialist of the Data to Knowledge Lab at Rice University

Startups and small businesses are accumulating data daily — here's how to use that to your advantage, according to this Houston expert. Photo via rice.edu

Ironically, the power of data management is almost incalculable. With the right practices and processes in place, businesses can make better decisions and grow more strategically. But, it's not something a lot of startups or small businesses look at regularly. That's where the Rice University Data To Knowledge group comes into play.

"Being able to interpret data and making data-driven decisions becomes the key to the success of a business," writes Shanna Jin in a guest column for InnovationMap. "It is not just a privilege for big companies anymore. Small businesses need it more than ever to make sustainable growth in the digital era." Click here to read more.

Trent Crow, founder and president of Real Simple Energy

Trent Crow, founder and president, and the Real Simple Energy team have moved over to Arcardia with the acquisition. Photo courtesy of Real Simple Energy

Earlier this month, a Houston startup exited to a larger tech company. Trent Crow, co-founder and CEO of Real Simply Energy, says all eight of the company's employees have moved over to Arcadia and more workers will be hired soon. The company has maintained a mix of office and remote workers. Arcadia will look for Houston office space later this year, Crow says.

"Expansion plans include doing more of what we're doing now and offering more features for customers," says Crow, who now is Arcadia's general manager of energy services in Texas. Click here to read more.

Startups and small businesses are accumulating data daily — here's how to use that to your advantage. Photo via Getty Images

Houston expert: How to use the power of data and analytics to inform ​small businesses​

Guest column

Starting a business in a digital era brings entrepreneurs unprecedented advantages with technology and tools designed to optimize a business' operation. Whether it is a B2C or B2B, business owners can gather almost any data and metrics to improve their performance.

Being able to interpret data and making data-driven decisions becomes the key to the success of a business. It is not just a privilege for big companies anymore. Small businesses need it more than ever to make sustainable growth in the digital era.

The challenge? There are countless analytic tools and resources available that can generate data, but you need people who can extract insights from the massive amount of data.

Hire a data science team vs. outsourcing

Many companies go to campus recruitment and scout bright data science talent who also identify with their business value. Hiring people with data science and analytic skills is optimal, but for startups that are not ready to hire an in-house team or have a short-term question, outsourcing is a better option.

Data science consulting

Many online resources can help you extract data, but you are probably wondering: where do I begin? Which tool should I use? Which exact metric should I track?

The Rice University's Data Science Consulting Clinic provides free, open to the public assistance to help clients with all of those questions. It can be for various business sectors, such as research and product development, cost predictions, analytic tools, acquisition decisions, and talent management.

Here are some of the data science aspects we specialize in:

Research & Development - Obtain data to inform a decision on what products to develop.
Data analysis of who your customers are, what they are interested in, and what product to develop is crucial for B2C and B2B. A recent example of how Rice's Data Science Consulting Clinic is making a difference is a client needed assistance with market research to help inform a startup on what kind of product they should create next. The client was able to use the data resources suggested by the student and faculty consultants to gauge consumer sentiment and examples of successful products. With the data collected, the client was able to identify the features that drive customers to purchase similar products.

Cost Predictions - A case study for an energy company
Businesses need to make crucial decisions to achieve business intelligence. CEOs and managers need to base their decisions on predictions and analysis. Another client from the Data Science Consulting Clinic was interested in predicting cost and analysis of the factors contributing to the most expense for the coming year. The client's main problem was to transform the data into a statistical model that could predict the cost. With the prediction model suggested by the student consultants, the client was able to reduce the cost by controlling factors that were likely to cause higher costs.

Acquisition Decision Making for Business Professionals
Clients from the Rice MBA program were interested in investigating the causes and effects of private equity (PE) acquisition. Specifically, the clients wanted to analyze the difference in practice habits before and after acquisitions. As a result of the consultation, the clients were able to determine what factors influenced the PE's decision to acquire new equity.

Longer term projects

It would be helpful to have a dedicated data science team who can work over a semester or year long to find the solution.

Higher education has placed a prominent focus on data science programs, especially capstone projects that provide students with real-world experience. As a business owner, you might not even think about working with an esteemed university to help you with data challenges.

The Center for Transforming Data to Knowledge, informally known as the D2K Lab at Rice University, is founded based on the mission to seek real-world data challenges for passionate data science students. Student teams have worked on over 50 sponsored data science projects with partners from a wide variety of businesses, organizations, and community partners.

Advance data science and security

The perk of working with Rice University is that it provides the most advanced data science research tools and an interdisciplinary pool of student and faculty talent who are passionate about data science. Working with Rice University also guarantees a strong data security system and a comprehensive confidentiality agreement.

  • A cloud-based financial company sponsored a series of capstone projects on applying deep learning to reduce documentation errors and increase efficiency for businesses.
  • A fintech company sponsored multiple capstone projects on building statistical models to predict costs.
  • In the tech-med industry, the D2K Lab has partnered with the Medical Informational Corps, and researchers from Texas Children's Hospital and Baylor College of Medicine to build algorithms to predict cardiac events.

The future of data-driven decision making

The digital era has become the norm for all businesses (large or small), and there's no way to avoid the power of transforming data into actionable insights. So start gathering data even before you build out a business and incorporate the culture of data-driven decision making into every sector of your business.

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Shanna Jin is the communications and marketing specialist of the Data to Knowledge Lab at Rice University.

The Rice D2K Lab wants to help startups and small businesses solve business concerns with data science. Photo courtesy of Rice University

Rice University's data-focused lab presents unique opportunity for startups and small businesses

data to knowlege

A data-focused lab at Rice University is training the next generation of data scientists. However, the students at the Rice D2K Lab are doing more than just learning about the significance of data, machine learning, and artificial intelligence — they're working as data scientists now.

Businesses — large and small — can come into the lab and have Rice students and faculty work on data projects in both short-term and long-term capacity. One semester, a group of students worked with 311 call data for the city of Houston so that officials can figure out what parts of town were in the most need of support, says Jennifer Sanders, program administrator at the Rice D2K lab.

"They were able to show on a Houston map the areas where most of these 311 calls were coming from," Sanders tells InnovationMap. "That allowed the city to focus on those areas."

Lately, the lab has been focused on a several COVID-19 Houston Response Projects, which addressed issues ranging from homelessness in the time of a pandemic, ventilator distribution, and more. One team even made a recommendation to the city after a data project determined that adding five ambulances to southwest neighborhoods served by the Houston Fire Department Emergency Medical Services program would optimize response times.

The lab has two avenues to help businesses: a semester-long capstone course and a clinic for one-time sessions. This upcoming semester, the capstone course has 60 students signed up to work on 10 to 12 projects from corporate sponsors. These lab members — which support the program monetarily — are selected based on their fit within the program.

The D2K Consulting Clinic also offers free one-hour sessions on campus. At the clinic, students look at the data and assess the possibilities and advise on how to use that data for business gain or growth.

"The consulting clinic can be a starting point if a business is not sure what to do with their data," says Shanna Jin, communications and marketing specialist at the D2K Lab.

The clinic also presents a special opportunity for small businesses and startups, a niche Sanders says they haven't tapped into enough yet. She says most of the companies they've worked with are larger organizations, usually in the energy industry.

"We really want to broaden the scope to smaller startups, tech companies, and nonprofits," Sanders says. "We really don't have to limit ourselves. I would really love to expand our reach."

Membership dues for companies, which provides a more structured, long-term access to data consulting, range from $25,000 to $75,000 a year. However, Sanders says the lab is willing to work with startups on a cost that's more accessible.

Ultimately, the goal of the program is to connect the dots for businesses that have data and don't know how to use it.

"To realize the potential of big data, we need people — people who can transform data to knowledge," says the lab's founder, Genevera Allen, in a promotional video. "That's what we're doing with the Rice D2K Lab."

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New 'living pharmacy' biotech company launches out of Rice venture studio

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Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”

Houston energy hub opens new fundraising cohort to fuel startups

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EnergyTech Cypher has opened applications for its second Liftoff fundraising program.

Applications close May 20 for the 10-week virtual fundraising sprint. The program is geared toward energy and climatech founders preparing to raise their first institutional round. It will cover fundraising requisites, like pitch materials, term sheet negotiation and round closing, according to a release from EnergyTech Cypher.

The program kicks off June 1 and runs every Monday from 1-3 p.m. CST. It will conclude with an in-person capstone simulation in Houston on August 3, where founders will work to close a mock round.

Jason Ethier, EnergyTech Cypher founder and CEO, will lead the program with Payal Patel, an EnergyTech fellow and entrepreneur in residence.

The program is available through Cephyron, EnergyTech Cypher's new investor relationship management platform, built specifically for energy and climatech founders. Users must have a Cephyron Boost membership to participate in the Liftoff program.

The Cephyron IRM app recently went live and is available to founders at any point in their fundraising process, according to the news release. The platform aggregates investor data, tracks market signals and delivers curated weekly recommendations.

EnergyTech Cypher launched Liftoff last year. The inaugural cohort included 19 startups, including Houston-based AtmoSpark Technologies, The Woodlands-based Resollant and others. Each participant closed at least one fundraising deal, according to EnergyTech Cypher.

EnergyTech Cypher rebranded from EnergyTech Nexus earlier this year. It also launched its CoPilot accelerator in 2025. The inaugural group presented its first showcase during CERAWeek last month.

EnergyTech Cypher's annual Pilotathon Pilot Pitch and Showcase applications also opened this month. Find more information here.

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This article originally appeared on EnergyCaptialHTX.com.

Cancer diagnostics startup wins top prize at annual Rice competition​

winner, winners

Rice University student-founded companies took home a total of $115,000 in equity-free funding at the annual Liu Idea Lab for Innovation and Entrepreneurship's H. Albert Napier Rice Launch Challenge last week.

2025 Rice Innovation Fellow Alexandria Carter won the top prize and $50,000 for her startup Bionostic. The startup offers personalized diagnostics for cancer patients by using 3D culturing through its Advanced Tumor Landscape Analysis System (ATLAS) platform.

Carter is working toward her PhD in bioengineering in Professor Michael King's laboratory. She recently completed the Rice Innovation Fellows program and plans to commercialize ATLAS, according to a news release from Rice.

Actile Technologies, founded by another former Rice Innovation Fellow, Barclay Jumet, won second place and $25,000. The company is developing and commercializing textile-integrated technologies. InnovationMap first covered Jumet's wearable technology back in 2023.

Kairos took home the third-place prize and $15,000, plus the $2,000 audience choice award and the $5,000 undergraduate business award. Founded last year by Sanjana Kavula and Adhira Tippur, Kairos is an AI-powered patient intake platform built specifically for independent dental practices.

The NRLC features top startups founded by undergraduate, graduate and MBA students at Rice each year. The top three finishers were named among a group of five finalists earlier this year, which also included HAAST Autonomous and Project Kestrel.

HAAST is developing an unmanned aircraft for organ transport, while Kestrel uses machine learning to organize bird photographers’ photo collections.

Teams presented multiple five-minute pitches throughout the application process over Zoom and in-person before the five finalists presented at the NRLC Championships April 21 at the Rice Memorial Center. Each finalist walked away with an equity-free investment.


Other awards went to:

UnitCode

  • $5,000 MBA Venture Award

HAAST Autonomous

  • $2,500 Chan-Kang Family Prize for Bold Ambition
  • $1,000 Healthcare Innovations Prize

Telstar Networks

  • $2,500 Outstanding Undergraduate Startup Award

Multiplay

  • $1,500 Frank Liu Jr. Prize for Creative Innovation in Music, Fashion, & the Arts

Butterfly Books

  • $1,500 Social Impact Award

SOOZ

  • $1,000 Interdisciplinary Innovation Prize sponsored by OURI

Dooly

  • $1,000 Consumer Goods Prize

Project Kestrel

  • $1,000 AI Prize

Veloci Running won the NRLC last year for its naturally shaped running shoe. Founder and CEO Tyler Strothman recently told InnovationMap that the company has gone on to sell roughly 10,000 pairs of its flagship Ascent shoe, designed to relieve lower leg tightness and absorb impact. Read more here.

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