3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Moji Karimi of Cemvita Factory, Shanna Jin of Rice University, and Trent Crow of Real Simple Energy. Courtesy photos

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — data science, consumer tech, and medical device innovation — recently making headlines in Houston innovation.

Moji Karimi, co-founder and CEO of Cemvita Factory

Moji Karimi joins the Houston Innovators Podcast to discuss how his technology is offering energy execs an innovative way to meat their climate change pledge goals. Photo courtesy of Cemvita

A lot of startups are working on technology that makes existing practices more efficient, cheaper, or faster — or all of the above. But Cemvita Factory, founded by siblings Moji and Tara Karimi, is doing something that's never been done before: biomimicking photosynthesis to convert carbon emissions into useful chemicals.

"There weren't biotech companies working with oil and gas companies for this use case that we have now," Moji Karimi says on this week's episode of the Houston Innovators Podcast. "We're defining this new category for application of synthetic biology in heavy industries for decarbonization."

With this uncharted territory comes unique challenges and opportunities. Click here to read more and stream the episode.

Shanna Jin, communications and marketing specialist of the Data to Knowledge Lab at Rice University

Startups and small businesses are accumulating data daily — here's how to use that to your advantage, according to this Houston expert. Photo via rice.edu

Ironically, the power of data management is almost incalculable. With the right practices and processes in place, businesses can make better decisions and grow more strategically. But, it's not something a lot of startups or small businesses look at regularly. That's where the Rice University Data To Knowledge group comes into play.

"Being able to interpret data and making data-driven decisions becomes the key to the success of a business," writes Shanna Jin in a guest column for InnovationMap. "It is not just a privilege for big companies anymore. Small businesses need it more than ever to make sustainable growth in the digital era." Click here to read more.

Trent Crow, founder and president of Real Simple Energy

Trent Crow, founder and president, and the Real Simple Energy team have moved over to Arcardia with the acquisition. Photo courtesy of Real Simple Energy

Earlier this month, a Houston startup exited to a larger tech company. Trent Crow, co-founder and CEO of Real Simply Energy, says all eight of the company's employees have moved over to Arcadia and more workers will be hired soon. The company has maintained a mix of office and remote workers. Arcadia will look for Houston office space later this year, Crow says.

"Expansion plans include doing more of what we're doing now and offering more features for customers," says Crow, who now is Arcadia's general manager of energy services in Texas. Click here to read more.

Startups and small businesses are accumulating data daily — here's how to use that to your advantage. Photo via Getty Images

Houston expert: How to use the power of data and analytics to inform ​small businesses​

Guest column

Starting a business in a digital era brings entrepreneurs unprecedented advantages with technology and tools designed to optimize a business' operation. Whether it is a B2C or B2B, business owners can gather almost any data and metrics to improve their performance.

Being able to interpret data and making data-driven decisions becomes the key to the success of a business. It is not just a privilege for big companies anymore. Small businesses need it more than ever to make sustainable growth in the digital era.

The challenge? There are countless analytic tools and resources available that can generate data, but you need people who can extract insights from the massive amount of data.

Hire a data science team vs. outsourcing

Many companies go to campus recruitment and scout bright data science talent who also identify with their business value. Hiring people with data science and analytic skills is optimal, but for startups that are not ready to hire an in-house team or have a short-term question, outsourcing is a better option.

Data science consulting

Many online resources can help you extract data, but you are probably wondering: where do I begin? Which tool should I use? Which exact metric should I track?

The Rice University's Data Science Consulting Clinic provides free, open to the public assistance to help clients with all of those questions. It can be for various business sectors, such as research and product development, cost predictions, analytic tools, acquisition decisions, and talent management.

Here are some of the data science aspects we specialize in:

Research & Development - Obtain data to inform a decision on what products to develop.
Data analysis of who your customers are, what they are interested in, and what product to develop is crucial for B2C and B2B. A recent example of how Rice's Data Science Consulting Clinic is making a difference is a client needed assistance with market research to help inform a startup on what kind of product they should create next. The client was able to use the data resources suggested by the student and faculty consultants to gauge consumer sentiment and examples of successful products. With the data collected, the client was able to identify the features that drive customers to purchase similar products.

Cost Predictions - A case study for an energy company
Businesses need to make crucial decisions to achieve business intelligence. CEOs and managers need to base their decisions on predictions and analysis. Another client from the Data Science Consulting Clinic was interested in predicting cost and analysis of the factors contributing to the most expense for the coming year. The client's main problem was to transform the data into a statistical model that could predict the cost. With the prediction model suggested by the student consultants, the client was able to reduce the cost by controlling factors that were likely to cause higher costs.

Acquisition Decision Making for Business Professionals
Clients from the Rice MBA program were interested in investigating the causes and effects of private equity (PE) acquisition. Specifically, the clients wanted to analyze the difference in practice habits before and after acquisitions. As a result of the consultation, the clients were able to determine what factors influenced the PE's decision to acquire new equity.

Longer term projects

It would be helpful to have a dedicated data science team who can work over a semester or year long to find the solution.

Higher education has placed a prominent focus on data science programs, especially capstone projects that provide students with real-world experience. As a business owner, you might not even think about working with an esteemed university to help you with data challenges.

The Center for Transforming Data to Knowledge, informally known as the D2K Lab at Rice University, is founded based on the mission to seek real-world data challenges for passionate data science students. Student teams have worked on over 50 sponsored data science projects with partners from a wide variety of businesses, organizations, and community partners.

Advance data science and security

The perk of working with Rice University is that it provides the most advanced data science research tools and an interdisciplinary pool of student and faculty talent who are passionate about data science. Working with Rice University also guarantees a strong data security system and a comprehensive confidentiality agreement.

  • A cloud-based financial company sponsored a series of capstone projects on applying deep learning to reduce documentation errors and increase efficiency for businesses.
  • A fintech company sponsored multiple capstone projects on building statistical models to predict costs.
  • In the tech-med industry, the D2K Lab has partnered with the Medical Informational Corps, and researchers from Texas Children's Hospital and Baylor College of Medicine to build algorithms to predict cardiac events.

The future of data-driven decision making

The digital era has become the norm for all businesses (large or small), and there's no way to avoid the power of transforming data into actionable insights. So start gathering data even before you build out a business and incorporate the culture of data-driven decision making into every sector of your business.

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Shanna Jin is the communications and marketing specialist of the Data to Knowledge Lab at Rice University.

The Rice D2K Lab wants to help startups and small businesses solve business concerns with data science. Photo courtesy of Rice University

Rice University's data-focused lab presents unique opportunity for startups and small businesses

data to knowlege

A data-focused lab at Rice University is training the next generation of data scientists. However, the students at the Rice D2K Lab are doing more than just learning about the significance of data, machine learning, and artificial intelligence — they're working as data scientists now.

Businesses — large and small — can come into the lab and have Rice students and faculty work on data projects in both short-term and long-term capacity. One semester, a group of students worked with 311 call data for the city of Houston so that officials can figure out what parts of town were in the most need of support, says Jennifer Sanders, program administrator at the Rice D2K lab.

"They were able to show on a Houston map the areas where most of these 311 calls were coming from," Sanders tells InnovationMap. "That allowed the city to focus on those areas."

Lately, the lab has been focused on a several COVID-19 Houston Response Projects, which addressed issues ranging from homelessness in the time of a pandemic, ventilator distribution, and more. One team even made a recommendation to the city after a data project determined that adding five ambulances to southwest neighborhoods served by the Houston Fire Department Emergency Medical Services program would optimize response times.

The lab has two avenues to help businesses: a semester-long capstone course and a clinic for one-time sessions. This upcoming semester, the capstone course has 60 students signed up to work on 10 to 12 projects from corporate sponsors. These lab members — which support the program monetarily — are selected based on their fit within the program.

The D2K Consulting Clinic also offers free one-hour sessions on campus. At the clinic, students look at the data and assess the possibilities and advise on how to use that data for business gain or growth.

"The consulting clinic can be a starting point if a business is not sure what to do with their data," says Shanna Jin, communications and marketing specialist at the D2K Lab.

The clinic also presents a special opportunity for small businesses and startups, a niche Sanders says they haven't tapped into enough yet. She says most of the companies they've worked with are larger organizations, usually in the energy industry.

"We really want to broaden the scope to smaller startups, tech companies, and nonprofits," Sanders says. "We really don't have to limit ourselves. I would really love to expand our reach."

Membership dues for companies, which provides a more structured, long-term access to data consulting, range from $25,000 to $75,000 a year. However, Sanders says the lab is willing to work with startups on a cost that's more accessible.

Ultimately, the goal of the program is to connect the dots for businesses that have data and don't know how to use it.

"To realize the potential of big data, we need people — people who can transform data to knowledge," says the lab's founder, Genevera Allen, in a promotional video. "That's what we're doing with the Rice D2K Lab."

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Intuitive Machines forms partnership with Italian companies for lunar exploration services

to the moon

Houston-based space technology, infrastructure and services company Intuitive Machines has forged a partnership with two Italian companies to offer infrastructure, communication and navigation services for exploration of the moon.

Intuitive Machines’ agreement with the two companies, Leonardo and Telespazio, paves the way for collaboration on satellite services for NASA, a customer of Intuitive Machines, and the European Space Agency, a customer of Leonardo and Telespazio. Leonardo, an aerospace, defense and security company, is the majority owner of Telespazio, a provider of satellite technology and services.

“Resilient, secure, and scalable space infrastructure and space data networks are vital to customers who want to push farther on the lunar surface and beyond to Mars,” Steve Altemus, co-founder and CEO of Intuitive Machine, said in a news release.

Massimo Claudio Comparini, managing director of Leonardo’s space division, added that the partnership with Intuitive Machines is a big step toward enabling human and robotic missions from the U.S., Europe and other places “to access a robust communications network and high-precision navigation services while operating in the lunar environment.”

Intuitive Machines recently expanded its Houston Spaceport facilities to ramp up in-house production of satellites. The company’s first satellite will launch with its upcoming IM‑3 lunar mission.

Intuitive Machines says it ultimately wants to establish a “center of space excellence” at Houston Spaceport to support missions to the moon, Mars and the region between Earth and the moon.

Houston hospitals win $50M grant for ibogaine addiction treatment research

ibogaine funding

The Texas Health and Human Services Commission has awarded $50 million to UTHealth Houston in collaboration with The University of Texas Medical Branch at Galveston (UTMB Health) to co-lead a multicenter research trial to evaluate the effect of ibogaine, a powerful psychoactive compound, on patients suffering from addiction, traumatic brain injury and other behavioral health conditions.

The funding will establish a two-year initiative—known as Ibogaine Medicine for PTSD, Addiction, and Cognitive Trauma (IMPACT)—and a consortium of Texas health institutions focused on clinical trials and working toward potential FDA-approved treatments.

The consoritum will also include Texas Tech University, Texas Tech University Health Sciences Center El Paso, The University of Texas at Austin, The University of Texas Health Science Center at San Antonio, The University of Texas at Tyler, The University of Texas Rio Grande Valley, Texas A&M University, The University of North Texas Health Science Center, Baylor College of Medicine and JPS Health Network in Dallas.

Ibogaine is a plant-based, psychoactive substance derived from the iboga shrub. Research suggests that the substance could be used for potential treatment for patients with traumatic brain injuries, which is a leading cause of post-traumatic stress disorders. Ibogaine has also shown potential as a treatment for addiction and other neurological conditions.

UTHealth and partners will focus on ways that ibogaine can treat addiction and associated conditions. Meanwhile, UT Austin and Baylor College of Medicine will concentrate on using it to treat traumatic brain injury, especially in veterans, according to a news release from the institutions.

The consortium will also support drug developers and teaching hospitals to conduct FDA-approved clinical trials. The Texas Health and Human Services Commission will oversee the grant program.

“This landmark clinical trial reflects our unwavering commitment to advancing research that improves lives and delivers the highest standards of care,” Dr. Melina Kibbe, UTHealth Houston president and the Alkek-Williams Distinguished Chair, said in the news release. “By joining forces with outstanding partners across our state, we are building on Texas’ tradition of innovation to ensure patients struggling with addiction and behavioral health conditions have access to the best possible outcomes. Together, we are shaping discoveries that will serve Texans and set a model for the nation.”

The consortium was authorized by the passage of Senate Bill 2308. The bill provides $50 million in state-matching funds for an ibogaine clinical trial managed by a public university in partnership with a drug company and a hospital.

“This is the first major step towards the legislature’s goal of obtaining FDA approval through clinical trials of ibogaine — a potential breakthrough medication that has brought thousands of America’s war-fighters back from the darkest parts of depression, anxiety, PTSD, and chronic addiction,” Texas Rep. Cody Harris added in the release. “I am excited to walk alongside UTHealth Houston and UTMB as these stellar institutions lead the nation in a first-of-its-kind clinical trial in the U.S.”

Recently, the University of Houston also received a $2.6 million gift from the estate of Dr. William A. Gibson to support and expand its opioid addiction research, which includes the development of a fentanyl vaccine that could block the drug's ability to enter the brain. Read more here.

Tesla no longer world's biggest EV maker as sales fall for second year

Tesla Talk

Tesla lost its crown as the world’s bestselling electric vehicle maker as a customer revolt over Elon Musk’s right-wing politics, expiring U.S. tax breaks for buyers and stiff overseas competition pushed sales down for a second year in a row.

Tesla said that it delivered 1.64 million vehicles in 2025, down 9% from a year earlier.

Chinese rival BYD, which sold 2.26 million vehicles last year, is now the biggest EV maker.

It's a stunning reversal for a car company whose rise once seemed unstoppable as it overtook traditional automakers with far more resources and helped make Musk the world's richest man. The sales drop came despite President Donald Trump's marketing effort early last year when he called a press conference to praise Musk as a “patriot” in front of Teslas lined up on the White House driveway, then announced he would be buying one, bucking presidential precedent to not endorse private company products.

For the fourth quarter, Tesla sales totaled 418,227, falling short of even the much reduced 440,000 target that analysts recently polled by FactSet had expected. Sales were hit hard by the expiration of a $7,500 tax credit for electric vehicle purchases that was phased out by the Trump administration at the end of September.

Tesla stock fell 2.6% to $438.07 on Friday.

Even with multiple issues buffeting the company, investors are betting that Tesla CEO Musk can deliver on his ambitions to make Tesla a leader in robotaxi services and get consumers to embrace humanoid robots that can perform basic tasks in homes and offices. Reflecting that optimism, the stock finished 2025 with a gain of approximately 11%.

The latest quarter was the first with sales of stripped-down versions of the Model Y and Model 3 that Musk unveiled in early October as part of an effort to revive sales. The new Model Y costs just under $40,000 while customers can buy the cheaper Model 3 for under $37,000. Those versions are expected to help Tesla compete with Chinese models in Europe and Asia.

For fourth-quarter earnings coming out in late January, analysts are expecting the company to post a 3% drop in sales and a nearly 40% drop in earnings per share, according to FactSet. Analysts expect the downward trend in sales and profits to eventually reverse itself as 2026 rolls along.

Musk said earlier last year that a “major rebound” in sales was underway, but investors were unruffled when that didn't pan out, choosing instead to focus on Musk's pivot to different parts of business. He has has been saying the future of the company lies with its driverless robotaxis service, its energy storage business and building robots for the home and factory — and much less with car sales.

Tesla started rolling out its robotaxi service in Austin in June, first with safety monitors in the cars to take over in case of trouble, then testing without them. The company hopes to roll out the service in several cities this year.

To do that successfully, it needs to take on rival Waymo, which has been operating autonomous taxis for years and has far more customers. It also will also have to contend with regulatory challenges. The company is under several federal safety investigations and other probes. In California, Tesla is at risk of temporarily losing its license to sell cars in the state after a judge there ruled it had misled customers about their safety.

“Regulatory is going to be a big issue,” said Wedbush Securities analyst Dan Ives, a well-known bull on the stock. “We're dealing with people's lives.”

Still, Ives said he expects Tesla's autonomous offerings will soon overcome any setbacks.

Musk has said he hopes software updates to his cars will enable hundreds of thousands of Tesla vehicles to operate autonomously with zero human intervention by the end of this year. The company is also planning to begin production of its AI-powered Cybercab with no steering wheel or pedals in 2026.

To keep Musk focused on the company, Tesla’s directors awarded Musk a potentially enormous new pay package that shareholders backed at the annual meeting in November.

Musk scored another huge windfall two weeks ago when the Delaware Supreme Court reversed a decision that deprived him of a $55 billion pay package that Tesla doled out in 2018.

Musk could become the world's first trillionaire later this year when he sells shares of his rocket company SpaceX to the public for the first time in what analysts expect would be a blockbuster initial public offering.

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