A oil and gas CEO, a serial entrepreneur, and a retail energy exec walk into the state capital. Getty Images

The Bayou City now wields some high-profile power in the state's economic development efforts.

The Texas Senate recently endorsed Gov. Greg Abbott's appointment of three business leaders with strong ties to Houston to the board of the Texas Economic Development Corp. — including the organization's new chair and vice chair.

Robert Allen, president and CEO of Texas' nonprofit economic development arm, says the Bayou City should feel well-represented on the board with former Houston Astros owner Drayton McLane as the new chair, Houston energy executive Vicki Hollub as the new vice chair, and Houston energy executive Scott Prochazka as a new member. That means Houston-connected business leaders hold three of the board's eight seats.

Allen calls McLane "the perfect Texas ambassador."

McLane, who lives in Temple, sold the Astros to Houston businessman Jim Crane in 2011 for $680 million. Forbes estimates McLane's net worth at $2.4 billion.

Today, McLane controls a Temple-based holding company with business interests such as food distribution, car dealerships and sports marketing. In 1991, he sold grocery distributor McLane Co. to Walmart, which later sold it to Warren Buffett's Berkshire Hathaway.

"I can think of no one better to lead our efforts to market the state of Texas as the best state for business than Drayton McLane. He has achieved tremendous success in several areas of business, all while calling Texas home," Allen tells InnovationMap.

McLane also chairs the board of Texas Central Partners, the Dallas company developing high-speed rail service between Houston and Dallas-Fort Worth. In addition, he serves on the boards of the George H.W. Bush Presidential Library Foundation, Baylor Scott & White Healthcare, and the Cooper Institute.

"I am privileged to be able to give service to our great state of Texas and honored by Gov. Abbott's appointment as chair of the Texas Economic Development Corporation," McLane says in a statement provided to InnovationMap.

"The goal of the corporation is to help market Texas as a place for businesses to grow and prosper," he adds. "Texas is a great state, and we have much to offer businesses in many sectors. I care deeply for Texas and improving the economy that will carry us into the future."

Hollub, president and CEO of Houston-based oil and gas company Occidental Petroleum, is the new vice chair of the Texas Economic Development Corp. She's spent 35 years at Occidental, which just hammered out a $57 billion deal to take over Anadarko Petroleum, an oil and gas company based in The Woodlands.

In addition to the board of the Texas Economic Development Corp., Hollub sits on the boards of Lockheed Martin and the American Petroleum Institute, and she is U.S. chair of the U.S.-Colombia Business Council.

"As the first female to head a major oil and gas company in the world, Vicki defines what it means to be a Texan — hardworking, determined, and incredibly smart," Allen says.

Prochazka, president and CEO of CenterPoint Energy, a Houston-based provider of electric and natural gas service, joins McLane and Hollub on the board of the Texas Economic Development Corp. Aside from his duties at CenterPoint, Prochazka is incoming chairman of the American Gas Association, chairman of Central Houston Inc., and a board member of the Greater Houston Partnership.

Given his roles with Central Houston Inc. and the Greater Houston Partnership, Prochazka knows Houston "intimately well," Allen says.

The Texas Economic Development Corp. is an independently funded and operated nonprofit that promotes economic development, business recruitment, and job creation in Texas. For instance, the nonprofit helped pave the way for a $15 billion liquefied natural gas (LNG) export facility in Corpus Christi that recently made its first cargo shipment. Houston-based Cheniere Energy owns the facility.

With Abbott's appointment of eight members, the makeup of the economic development organization's eight-member board is entirely new. The governor appointed them in April, but the state Senate had to give its final approval, which came earlier this month.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”