3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Adrianne Stone of Bayou City Startups, Sarma Velamuri of Luminare, and Curtis Jackson of G-Unity Foundation. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to nonprofit — recently making headlines in Houston innovation.

Adrianne Stone, founder of Bayou City Startups

Every month, Adrianne Stone of Bayou City Startups hosts a happy hour for startup founders to create a safe space to network, collaborate, commensurate, and more. Photo courtesy of Adrianne Stone

Adrianne Stone knows firsthand how lonely the startup founder journey is, so she set out to help create a community for founders when she started Bayou City Startups last year. Now, Stone shares on the Houston Innovators Podcast that her monthly happy hours attract over 50 attendees on average.

"Being the venture associate with Capital Factory in Houston, I'd seen what the Houston ecosystem had to offer. There were events — happy hours, coffee meet-ups, all these things," Stone says on the show. "But it was not just a casual networking event usually. I wanted a consistent community where I could show up and say, 'guys, I had the worst week,' to people who got where I was coming from and who could commensurate or lean in and help."

The next opportunity to network with Bayou City Startups is Tuesday, July 18, from 5 to 7 pm at Kirby Ice House. Read more.

Sarma Velamuri, co-founder and CEO of Luminare

Sepsis has been the No. 1 killer hospitals, but this Houston startup has a tech to help mitigate the risk. Photo via Getty Images

When he was an internal medicine physician, Sarma Velamuri watched helplessly as a friend’s 22-year-old daughter lost her life to sepsis. He had to tell his friend that she would not be coming home.

“There are 300,000-plus people a year who die of sepsis,” says Velamuri. “It’s important that people understand it’s not just those who are most susceptible to infections.”

This fact is not only unfortunate, but preventable. And that’s why Velamuri, who describes himself as “a recovering hospitalist,” co-founded Luminare in 2014. A full-time CEO since 2017, Velamuri, who runs the company with co-founder and CTO Marcus Rydberg, is based in the TMC Innovation Factory. Read more.

Curtis Jackson, founder of the G-Unity Foundation

For the second year, Curtis Jackson's program supported Houston student entrepreneurs. Photo courtesy of G-Unity

Chances are, you've heard of 50 Cent — his 2003 album "Get Rich or Die Tryin'" was a soundtrack to many. But Curtis James Jackson III, 50 Cent's real name, has done a lot since gracing your radios. He moved to Houston in 2021 and founded the G-Unity Foundation. In May, he wrapped on the second year of the G-Unity Business Labs, a business development incubator for Houston Independent School District high schoolers.

"I’ve spent years donating my time and energy to communities in need. I started G-Unity to do the same—to give back to kids so they have it a little easier than I did," Jackson writes on the website. "Team building and entrepreneurship are skills I learned along the way, but they are so important to develop early. I look forward to G-Unity supporting programs that are doing the crucial work of teaching kids to excel at life."

Around 150 students participated, and the winners are splitting a $500,000 investment. Read more.

Sepsis has been the No. 1 killer hospitals, but this Houston startup has a tech to help mitigate the risk. Photo via Getty Images

Houston startup taps into AI to help prevent leading cause in hospital death

coming for sepsis

Anyone can die of sepsis. The number one killer in hospitals has a reputation for felling the infirm and elderly, but while the immunocompromised are at highest risk, sepsis isn’t that selective.

Take 12-year-old Rory Staunton. In 2012, the healthy boy scratched his arm diving for a ball in gym class at his school in Jackson Heights, NY. Bacteria entered his arm through the cut and he died days later of septic shock.

His story is not unique. Physician Sarma Velamuri saw this firsthand in his internal medicine practice at St. Luke’s Health Center and his residency at Baylor, both in Houston. But it really struck home when he watched helplessly as a friend’s 22-year-old daughter lost her life to sepsis. He had to tell his friend that she would not be coming home.

“There are 300,000-plus people a year who die of sepsis,” says Velamuri. “It’s important that people understand it’s not just those who are most susceptible to infections.”

This fact is not only unfortunate, but preventable. And that’s why Velamuri, who describes himself as “a recovering hospitalist,” co-founded Luminare in 2014. A full-time CEO since 2017, Velamuri, who runs the company with co-founder and CTO Marcus Rydberg, is based in the TMC Innovation Factory.

“Because of the complex workflows in hospitals, sometimes it takes 10 people to get the patient the care they need,” Velamuri explains.

And because of the pervasiveness of sepsis, it’s important to screen every patient who enters an institution before it gets to that point.

Luminare’s technology allows nurses, who are notoriously spread thin, to automatically screen patients in 10 seconds using 50 different parameters.

“We’re looking at a vast amount of data simultaneously,” says Velamuri. “We’re not generating any new data, we’re taking data that exists and shining a light on it.”

In 2020, the technology found a new application when Velamuri and his team created a version of Luminare that helped with the hospital workflow surrounding COVID PCR testing and vaccine management. Since then, it has also been used to help identify and treat monkeypox.

Though Velamuri says he doesn’t want to distract Luminare from its goal of making sepsis the number-two killer in hospitals, he is also aware that his technology can be instrumental in identifying and treating patients at risk for countless other maladies, including heart failure and stroke, and even helping with oncology workflows.

Velamuri says that his team is Luminare’s biggest strength, far more than the AI that they have designed.

“I have this saying that AI is a great servant but a terrible master. It doesn’t solve the problem,” says Velamuri.

Though the company is distributed as far afield as Stockholm, about half of its people live and work in Houston. Of the company’s placement in TMC’s Innovation Factory, Velamuri says, “They’ve been tremendous partners to us. The company would not be as successful today without their supportive partnership.” Not least of that is working with in the same space as other founders who can share their expertise as easily as a trip to the coffee machine.

And the company is growing quickly. Last year, Luminare participated in Cedars-Sinai’s accelerator program. Thanks to that partnership, the hospital is now using Luminare’s technology for sepsis screening. The team is working to partner with even more large hospital systems on solutions for one of the health industry’s biggest problems. And data that shows that Luminare can be the path to preventing death from hospitals’ most prolific killer.

Sarma Velamuri went from MD to CEO when he founded Luminare. Photo via luminare.io

This week's roundup of Houston innovators includes Deanna Zhang of Tudor, Pickering, & Holt Co., Sarma Velamuri of Luminare, and Amy Chronis of Deloitte. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three innovators recently making headlines — from health tech founders to the new GHP chair.

Deeana Zhang, director of energy technology at Tudor, Pickering, Holt & Co.

Deanna Zhang of Tudor, Pickering, Holt & Co. joined the Houston Innovators Podcast to discuss 2020's effect on the energy transition — and what that meant for startups. Photo courtesy of TPH

Deanna Zhang looks closely at the energy innovation market and, well, last year was extremely enlightening about the energy industry and where tech is taking it. She joined the Houston Innovators Podcast last week to discuss some of the 2020 trends and observations she had — and what that means for 2021.

"The energy transition saw a huge uptick in 2020 — and there's a lot of implications of that from what pilots are getting commercialized and what companies are getting more funding," says Zhang. "All around it was hugely disruptive — but hugely beneficial I think to the energy transition." Click here to read more and stream the episode.

Dr. Sarma Velamuri, CEO of Luminare

A Houston health tech startup has launched a COVID-19 vaccine management tool. Image via luminaremed.com

As great as it was to be able to begin distributing the life-saving COVID-19 vaccine, the logistics of the two-dose process was a nightmare. Dr. Sarma Velamuri, CEO of Luminare, thought he could innovate a solution. His new platform, Innoculate (a mash-up of "innovate" and "inoculate"), enables organizations like public health departments, fire departments, school systems, and businesses to manage high-volume vaccination initiatives.

"Usually when you hear news of a new batch of vaccines headed your way, there is dread at the management and distribution overhead. Not anymore," Velamuri says in a release. "Innoculate will help streamline the vaccination process in the fight against COVID-19 and allow for hundreds of thousands of people to get vaccines easily." Click here to read more.

Amy Chronis, Greater Houston Partnership's 2021 chair and the Houston managing partner at Deloitte

Houston, we have a perception problem — but the Greater Houston Partnership's new chair, Amy Chronis, is here to fix it. Photo courtesy Deloitte/AlexandersPortraits.com

Hey Houston, it's time to speak up — a little louder for the people in the back. That's what Amy Chonis, 2021 chair for the Greater Houston Partnership, wants you to know, and that it's important for business leaders across the city to take the initiative about how great Houston is.

"We just don't brag enough about how much the city has changed and its trajectory," she tells InnovationMap.

While Houston has long been innovative in the health, space, and energy industries, it has a perception problem. Recently, Chronis addressed some of these concerns in her address at the GHP's 2021 Annual Meeting. She joined InnovationMap for an interview to zero in on how the business community can work to change this perception problem and continue to grow its innovation and tech community. Click here to read the Q&A.

Image via luminaremed.com

Houston health tech startup launches COVID-19 vaccine management tool

inoculation innovation

Houston-based health care software startup Luminare Inc. is arming soldiers in the coronavirus vaccination campaign with technology to help smooth the inoculation process.

Luminare, which launched with the mission of combating sepsis, switched gears after the onset of the coronavirus pandemic to help combat the virus' spread. One of the ways it's doing that is with Innoculate (a mash-up of "innovate" and "inoculate"). The new platform enables organizations like public health departments, fire departments, school systems, and businesses to manage high-volume vaccination initiatives.

Among other benefits, Innoculate automates vaccination sign-ups and scheduling, tracks the number of vaccine batches available, flags previous allergic reactions among vaccine recipients, and helps achieve compliance with federal, state and local health care requirements.

"Usually when you hear news of a new batch of vaccines headed your way, there is dread at the management and distribution overhead. Not anymore," Dr. Sarma Velamuri, CEO of Luminare, says in a release. "Innoculate will help streamline the vaccination process in the fight against COVID-19 and allow for hundreds of thousands of people to get vaccines easily."

One of the first customers of Innoculate is the Corpus Christi-Nueces County Public Health District. Innoculate helped the district vaccinate 9,000 people during the first week of its vaccination effort. Peter Collins, chief information officer of the City of Corpus Christi, says Innoculate allows more vaccinations to be done without adding administrative burdens.

Corpus Christi-Nueces County Public Health District was the first government outfit to use Innoculate. The district also uses Luminare's Quickscreen COVID-19 screening and testing tool.

Dallas County Health and Human Services also is adopting Innoculate. On January 27, Dallas County approved a 12-month contract with Luminare worth up to $601,500.

Other new customers that are lined up for Innoculate include the Abilene-Taylor County Public Health District, Wichita Falls-Wichita County Public Health District, and Brenham-based Blinn College District. Innoculate deals are being finalized with 13 other city and county governments.

Luminare says it wants to "help as many cities and counties in the U.S. that we can." The company asks organizations seeking help with coronavirus vaccination campaigns to email mike.gilbert@luminaremed.com or info@luminaremed.com.

Luminare was founded in 2014 with the goal of preventing sepsis, a life-threatening reaction to a host of infections that triggers about one-third of U.S. hospital deaths. Its sepsis-targeted software is called Sagitta.

After the coronavirus began spreading, Luminare tweaked its sepsis-detection platform, called Quickscreen, to produce a free online self-assessment for people who suspect they've been infected with the virus. The startup was honored for this work as COVID Phoenix in Houston Exponential's inaugural awards program, The Listies. Now, it has added Innoculate to its pandemic-fighting arsenal.

Luminare, based at Texas Medical Center's innovation campus, is a 2018 graduate of the TMCx accelerator. According to Crunchbase, the company has collected more than $1.6 million in funding.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

---

The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.



Rice University launches  engineering-led brain science and health institute

brain research

Rice University has announced the creation of a new interdisciplinary center known as the Rice Brain Institute (RBI).

The new hub will aim to use engineering, natural sciences and social sciences to research the brain and reduce the burden of neurodegenerative, neurodevelopmental and mental health disorders.

“The Rice Brain Institute reflects Rice’s strength in collaboration without boundaries,” Rachel Kimbro, dean of the School of Social Sciences, said in a news release. “Our researchers are not only advancing fundamental science but they’re also ensuring that knowledge reaches society in ways that promote human flourishing.”

RBI researchers will work in thematic clusters focusing on neurodegeneration, mental health, brain injury and neurodevelopment. The clusters will work toward goals such as significantly improving key brain health outcomes, reducing mortality and mental health disorders and improving quality of life for patients living with brain injuries and neurodevelopmental disorders, according to Rice.

The institute will focus on “engineering-driven innovation,” rather than traditional neuroscience, to design tools that can measure, model and modulate brain activity based around Rice’s expertise in soft robotics, neuroimaging, data science and artificial intelligence—making it unique among peer organizations, according to Rice.

Additionally, RBI will be structured around three collaborative Rice “pillars”:

  • The Neuroengineering Initiative, launched in 2018, brings together neuroscience, engineering, and related fields experts
  • The Neuroscience Initiative, a new initiative that brings together cell biologists, neurobiologists, biochemists, chemists and physicists to explore fundamental mechanisms of the brain and nervous system
  • The Brain and Society Initiative, also a new initiative, considers brain research within the broader social and policy landscape

Rice’s Neuroengineering Initiative has already garnered more than $78 million in research funding, according to Rice, and has established major partnerships, like the Rice-Houston Methodist Center for Neural Systems Restoration.

“Rice is uniquely equipped to bridge and connect scientific understanding of the brain and behavior sciences with the technologies and policies that shape our world,” Amy Dittmar, the Howard R. Hughes Provost and executive vice president for academic affairs, added in the news release. “By uniting faculty in neuroengineering, neuroscience and psychological sciences, this interdisciplinary hub embodies the kind of bold, nimble collaboration that allows Rice to turn discovery into societal impact to save lives and enhance human flourishing.”

The formation of the RBI coincides with recent support of the Dementia Prevention Research Institute of Texas (DPRIT), which landed voter approval earlier this week and aims to make Texas the center for dementia research via brain-health tech. According to the World Economic Forum, brain disorders and mental health disorders cost the global economy an estimated $5 trillion per year and could be as high as $16 trillion by 2030.

“Few areas of research have as direct and profound an impact on human well-being as brain health,” Rice President Reginald DesRoches added in the news release. “As rates of Alzheimer’s, dementia and other neurological diseases rise in our country and around the world, universities have a responsibility to lead the discovery of solutions that preserve memory, movement and quality of life. We all know someone who has been affected by a brain-related health issue, so this research is personal to all of us.”

Texas voters OK $3 billion for new dementia research institute

state funding

Texas voters on Nov. 4 overwhelmingly approved a ballot measure that provides $3 billion in state funding over a 10-year span for the newly established Dementia Prevention and Research Institute of Texas (DPRIT).

Thanks to the passage of Proposition 14, Texas now boasts the country’s largest state-funded initiative dedicated to dementia research and prevention, according to the Alzheimer’s Association. Up to $300 million in grants will be awarded during the 10-year funding period.

“This is a transformative moment for Texas and for the fight against Alzheimer’s and all other dementia,” said Joanne Pike, president and CEO of the Alzheimer’s Association. “Texans have chosen to invest in hope, innovation, and solutions for the millions of families affected by these devastating diseases. With the passage of Proposition 14, Texas is now poised to lead the nation in dementia research and prevention.”

The association says DPRIT will drive scientific breakthroughs, attract top-notch dementia researchers to Texas, and generate thousands of jobs statewide.

An estimated 460,000 Texans are living with dementia, the association says, and more than one million caregivers support them.

DPRIT is modeled after the Cancer Prevention and Research Institute of Texas (CPRIT). Since 2008, the state agency has awarded nearly $4 billion in grants to research organizations for cancer-related academic research, prevention programs, and product development.

An analysis by the McKinsey Health Institute found that investing in brain health initiatives like DPRIT could boost Texas’ GDP by $260 billion. Much of that GDP bump could benefit the Houston area, which is home to dementia-focused organizations such as UTHealth Houston Neurosciences, Baylor College of Medicine’s Center for Alzheimer’s and Neurodegenerative Diseases, the University of Texas Medical Branch at Galveston’s Collaborative Alzheimer’s Disease and Memory Disorders Program, and the Houston Methodist Research Institute’s John M. O’Quinn Foundation Neurodegenerative Disorders Laboratory.

The Greater Houston Partnership says DPRIT holds the potential “to elevate Texas — particularly Houston — as a hub for brain health research.”

State Sen. Joan Huffman, a Houston Republican, is one of DPRIT’s champions. She sponsored legislation this year to create the institute and ask Texas voters to approve the $3 billion in funding.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said in May. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our health care community.”

View All Listings