This week's roundup of Houston innovators includes Adrianne Stone of Bayou City Startups, Sarma Velamuri of Luminare, and Curtis Jackson of G-Unity Foundation. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health tech to nonprofit — recently making headlines in Houston innovation.

Adrianne Stone, founder of Bayou City Startups

Every month, Adrianne Stone of Bayou City Startups hosts a happy hour for startup founders to create a safe space to network, collaborate, commensurate, and more. Photo courtesy of Adrianne Stone

Adrianne Stone knows firsthand how lonely the startup founder journey is, so she set out to help create a community for founders when she started Bayou City Startups last year. Now, Stone shares on the Houston Innovators Podcast that her monthly happy hours attract over 50 attendees on average.

"Being the venture associate with Capital Factory in Houston, I'd seen what the Houston ecosystem had to offer. There were events — happy hours, coffee meet-ups, all these things," Stone says on the show. "But it was not just a casual networking event usually. I wanted a consistent community where I could show up and say, 'guys, I had the worst week,' to people who got where I was coming from and who could commensurate or lean in and help."

The next opportunity to network with Bayou City Startups is Tuesday, July 18, from 5 to 7 pm at Kirby Ice House. Read more.

Sarma Velamuri, co-founder and CEO of Luminare

Sepsis has been the No. 1 killer hospitals, but this Houston startup has a tech to help mitigate the risk. Photo via Getty Images

When he was an internal medicine physician, Sarma Velamuri watched helplessly as a friend’s 22-year-old daughter lost her life to sepsis. He had to tell his friend that she would not be coming home.

“There are 300,000-plus people a year who die of sepsis,” says Velamuri. “It’s important that people understand it’s not just those who are most susceptible to infections.”

This fact is not only unfortunate, but preventable. And that’s why Velamuri, who describes himself as “a recovering hospitalist,” co-founded Luminare in 2014. A full-time CEO since 2017, Velamuri, who runs the company with co-founder and CTO Marcus Rydberg, is based in the TMC Innovation Factory. Read more.

Curtis Jackson, founder of the G-Unity Foundation

For the second year, Curtis Jackson's program supported Houston student entrepreneurs. Photo courtesy of G-Unity

Chances are, you've heard of 50 Cent — his 2003 album "Get Rich or Die Tryin'" was a soundtrack to many. But Curtis James Jackson III, 50 Cent's real name, has done a lot since gracing your radios. He moved to Houston in 2021 and founded the G-Unity Foundation. In May, he wrapped on the second year of the G-Unity Business Labs, a business development incubator for Houston Independent School District high schoolers.

"I’ve spent years donating my time and energy to communities in need. I started G-Unity to do the same—to give back to kids so they have it a little easier than I did," Jackson writes on the website. "Team building and entrepreneurship are skills I learned along the way, but they are so important to develop early. I look forward to G-Unity supporting programs that are doing the crucial work of teaching kids to excel at life."

Around 150 students participated, and the winners are splitting a $500,000 investment. Read more.

Sepsis has been the No. 1 killer hospitals, but this Houston startup has a tech to help mitigate the risk. Photo via Getty Images

Houston startup taps into AI to help prevent leading cause in hospital death

coming for sepsis

Anyone can die of sepsis. The number one killer in hospitals has a reputation for felling the infirm and elderly, but while the immunocompromised are at highest risk, sepsis isn’t that selective.

Take 12-year-old Rory Staunton. In 2012, the healthy boy scratched his arm diving for a ball in gym class at his school in Jackson Heights, NY. Bacteria entered his arm through the cut and he died days later of septic shock.

His story is not unique. Physician Sarma Velamuri saw this firsthand in his internal medicine practice at St. Luke’s Health Center and his residency at Baylor, both in Houston. But it really struck home when he watched helplessly as a friend’s 22-year-old daughter lost her life to sepsis. He had to tell his friend that she would not be coming home.

“There are 300,000-plus people a year who die of sepsis,” says Velamuri. “It’s important that people understand it’s not just those who are most susceptible to infections.”

This fact is not only unfortunate, but preventable. And that’s why Velamuri, who describes himself as “a recovering hospitalist,” co-founded Luminare in 2014. A full-time CEO since 2017, Velamuri, who runs the company with co-founder and CTO Marcus Rydberg, is based in the TMC Innovation Factory.

“Because of the complex workflows in hospitals, sometimes it takes 10 people to get the patient the care they need,” Velamuri explains.

And because of the pervasiveness of sepsis, it’s important to screen every patient who enters an institution before it gets to that point.

Luminare’s technology allows nurses, who are notoriously spread thin, to automatically screen patients in 10 seconds using 50 different parameters.

“We’re looking at a vast amount of data simultaneously,” says Velamuri. “We’re not generating any new data, we’re taking data that exists and shining a light on it.”

In 2020, the technology found a new application when Velamuri and his team created a version of Luminare that helped with the hospital workflow surrounding COVID PCR testing and vaccine management. Since then, it has also been used to help identify and treat monkeypox.

Though Velamuri says he doesn’t want to distract Luminare from its goal of making sepsis the number-two killer in hospitals, he is also aware that his technology can be instrumental in identifying and treating patients at risk for countless other maladies, including heart failure and stroke, and even helping with oncology workflows.

Velamuri says that his team is Luminare’s biggest strength, far more than the AI that they have designed.

“I have this saying that AI is a great servant but a terrible master. It doesn’t solve the problem,” says Velamuri.

Though the company is distributed as far afield as Stockholm, about half of its people live and work in Houston. Of the company’s placement in TMC’s Innovation Factory, Velamuri says, “They’ve been tremendous partners to us. The company would not be as successful today without their supportive partnership.” Not least of that is working with in the same space as other founders who can share their expertise as easily as a trip to the coffee machine.

And the company is growing quickly. Last year, Luminare participated in Cedars-Sinai’s accelerator program. Thanks to that partnership, the hospital is now using Luminare’s technology for sepsis screening. The team is working to partner with even more large hospital systems on solutions for one of the health industry’s biggest problems. And data that shows that Luminare can be the path to preventing death from hospitals’ most prolific killer.

Sarma Velamuri went from MD to CEO when he founded Luminare. Photo via luminare.io

This week's roundup of Houston innovators includes Deanna Zhang of Tudor, Pickering, & Holt Co., Sarma Velamuri of Luminare, and Amy Chronis of Deloitte. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In the week's roundup of Houston innovators to know, I'm introducing you to three innovators recently making headlines — from health tech founders to the new GHP chair.

Deeana Zhang, director of energy technology at Tudor, Pickering, Holt & Co.

Deanna Zhang of Tudor, Pickering, Holt & Co. joined the Houston Innovators Podcast to discuss 2020's effect on the energy transition — and what that meant for startups. Photo courtesy of TPH

Deanna Zhang looks closely at the energy innovation market and, well, last year was extremely enlightening about the energy industry and where tech is taking it. She joined the Houston Innovators Podcast last week to discuss some of the 2020 trends and observations she had — and what that means for 2021.

"The energy transition saw a huge uptick in 2020 — and there's a lot of implications of that from what pilots are getting commercialized and what companies are getting more funding," says Zhang. "All around it was hugely disruptive — but hugely beneficial I think to the energy transition." Click here to read more and stream the episode.

Dr. Sarma Velamuri, CEO of Luminare

A Houston health tech startup has launched a COVID-19 vaccine management tool. Image via luminaremed.com

As great as it was to be able to begin distributing the life-saving COVID-19 vaccine, the logistics of the two-dose process was a nightmare. Dr. Sarma Velamuri, CEO of Luminare, thought he could innovate a solution. His new platform, Innoculate (a mash-up of "innovate" and "inoculate"), enables organizations like public health departments, fire departments, school systems, and businesses to manage high-volume vaccination initiatives.

"Usually when you hear news of a new batch of vaccines headed your way, there is dread at the management and distribution overhead. Not anymore," Velamuri says in a release. "Innoculate will help streamline the vaccination process in the fight against COVID-19 and allow for hundreds of thousands of people to get vaccines easily." Click here to read more.

Amy Chronis, Greater Houston Partnership's 2021 chair and the Houston managing partner at Deloitte

Houston, we have a perception problem — but the Greater Houston Partnership's new chair, Amy Chronis, is here to fix it. Photo courtesy Deloitte/AlexandersPortraits.com

Hey Houston, it's time to speak up — a little louder for the people in the back. That's what Amy Chonis, 2021 chair for the Greater Houston Partnership, wants you to know, and that it's important for business leaders across the city to take the initiative about how great Houston is.

"We just don't brag enough about how much the city has changed and its trajectory," she tells InnovationMap.

While Houston has long been innovative in the health, space, and energy industries, it has a perception problem. Recently, Chronis addressed some of these concerns in her address at the GHP's 2021 Annual Meeting. She joined InnovationMap for an interview to zero in on how the business community can work to change this perception problem and continue to grow its innovation and tech community. Click here to read the Q&A.

Image via luminaremed.com

Houston health tech startup launches COVID-19 vaccine management tool

inoculation innovation

Houston-based health care software startup Luminare Inc. is arming soldiers in the coronavirus vaccination campaign with technology to help smooth the inoculation process.

Luminare, which launched with the mission of combating sepsis, switched gears after the onset of the coronavirus pandemic to help combat the virus' spread. One of the ways it's doing that is with Innoculate (a mash-up of "innovate" and "inoculate"). The new platform enables organizations like public health departments, fire departments, school systems, and businesses to manage high-volume vaccination initiatives.

Among other benefits, Innoculate automates vaccination sign-ups and scheduling, tracks the number of vaccine batches available, flags previous allergic reactions among vaccine recipients, and helps achieve compliance with federal, state and local health care requirements.

"Usually when you hear news of a new batch of vaccines headed your way, there is dread at the management and distribution overhead. Not anymore," Dr. Sarma Velamuri, CEO of Luminare, says in a release. "Innoculate will help streamline the vaccination process in the fight against COVID-19 and allow for hundreds of thousands of people to get vaccines easily."

One of the first customers of Innoculate is the Corpus Christi-Nueces County Public Health District. Innoculate helped the district vaccinate 9,000 people during the first week of its vaccination effort. Peter Collins, chief information officer of the City of Corpus Christi, says Innoculate allows more vaccinations to be done without adding administrative burdens.

Corpus Christi-Nueces County Public Health District was the first government outfit to use Innoculate. The district also uses Luminare's Quickscreen COVID-19 screening and testing tool.

Dallas County Health and Human Services also is adopting Innoculate. On January 27, Dallas County approved a 12-month contract with Luminare worth up to $601,500.

Other new customers that are lined up for Innoculate include the Abilene-Taylor County Public Health District, Wichita Falls-Wichita County Public Health District, and Brenham-based Blinn College District. Innoculate deals are being finalized with 13 other city and county governments.

Luminare says it wants to "help as many cities and counties in the U.S. that we can." The company asks organizations seeking help with coronavirus vaccination campaigns to email mike.gilbert@luminaremed.com or info@luminaremed.com.

Luminare was founded in 2014 with the goal of preventing sepsis, a life-threatening reaction to a host of infections that triggers about one-third of U.S. hospital deaths. Its sepsis-targeted software is called Sagitta.

After the coronavirus began spreading, Luminare tweaked its sepsis-detection platform, called Quickscreen, to produce a free online self-assessment for people who suspect they've been infected with the virus. The startup was honored for this work as COVID Phoenix in Houston Exponential's inaugural awards program, The Listies. Now, it has added Innoculate to its pandemic-fighting arsenal.

Luminare, based at Texas Medical Center's innovation campus, is a 2018 graduate of the TMCx accelerator. According to Crunchbase, the company has collected more than $1.6 million in funding.

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Houston leads U.S. in population growth for 2025, Census says

Boomtown

Imagine that the Houston metro area swallowed a city the size of Pearland in just one year. That’s essentially what happened from 2024 to 2025, with the Houston metro ranking first in the U.S. for population growth based on the number of people.

New estimates from the U.S. Census Bureau show the 10-county Houston metro added 126,720 residents from July 1, 2024, to July 1, 2025. That’s just shy of Pearland’s roughly 133,000-resident tally.

To calculate population, the Census Bureau counts births, deaths, new residents, and moved-away residents.

Region’s population approaches 8 million

On July 1, 2025, the Houston metro’s population hovered slightly above 7.9 million, up 1.6 percent from the same time in 2024. In the very near future, the region’s population should break the eight million mark.

This follows massive growth in the past 20 years. From 2005 to 2025, the region’s population soared by 39 percent. By comparison, the growth rate from 2021 to 2025 sat at nine percent.

A forecast from the Texas Demographics Center indicates that under a middle-of-the-road scenario, the Houston metro’s population will reach nearly 8.5 million in mid-2030 and more than 9.5 million in mid-2040.

Dan Potter, director of Rice University’s Houston Population Research Center, attributes much of the region’s population surge to people moving to the area from outside the U.S. In Harris County, this means a combination of military personnel returning home, people living or working overseas coming back to the U.S., and immigrants relocating to the U.S., he tells CultureMap.

But Harris County fell short from 2024 to 2025 when it comes to people moving here from elsewhere in the U.S., according to Potter. Counties surrounding Harris County benefited from that trend, drawing new residents who preferred to settle in the suburbs.

“The incredible pull and attraction of the Houston area is its economy, its people, and its affordability, and the significant growth that was observed in 2024 and again in 2025 speaks to the magnetism of the region,” Potter says. “That pull to Houston is too strong to be turned off overnight.”

Cooling economy and immigration shifts slow down growth

Whether looking at urban or suburban places, population growth in the Houston area slowed in 2025 and appears to be slowing even more this year, Potter says.

“A cooling economy and changes to immigration policy are a one-two combination that could knock out the region’s population growth,” says Potter, citing the region’s addition of a less-than-expected 14,800 jobs in 2025 as an example.

Weaker population growth may not be felt evenly across the metro area, according to Potter.

A continuing influx of people from Houston to outlying counties such as Brazoria, Fort Bend, Liberty, Montgomery, and Waller could curb growth in Harris County, Potter said. Why? If the number of people arriving from other other countries flattens or even drops, then there could be “doughnut-style population growth for the next few years, where Harris County and Houston see declines while the suburban counties see an increase.”

Harris County represents 40 percent of region’s population lift

Houston-anchored Harris County accounted for almost 40 percent of the region’s population spike from 2024 to 2025. In one year, Harris County grew by 48,695 residents, or 1 percent, pushing its population past five million. That increase put Harris County in first place for numeric growth (rather than percentage growth) among all U.S. counties.

From 2020 to 2025, Harris County’s growth rate was 6.6 percent. It remains the country’s third largest county based on population, behind Southern California’s Los Angeles County and Illinois’ Chicago-anchored Cook County.

Harris County is on track to surpass Cook County in size in the near future. As of July 1, 2025, a nearly 150,000-resident gap separated population-losing Cook County and fast-growing Harris County.

The Texas Demographics Center predicts Harris County’s population will be 5.37 million in mid-2030 and just short of six million in mid-2040.

Suburban counties see significant population gains

Harris County isn’t the only county in the area that experienced a growth spurt from 2024 to 2025:

  • Waller County’s population climbed 5.69 percent, winding up at 69,858. Its growth rate ranked second among U.S. counties.
  • Liberty County’s population rose 4.4 percent to 121,364, putting its growth rate in eighth place among U.S. counties.
  • Montgomery County gained 30,011 residents, with its population landing at 781,194. That placed it at No. 4 among U.S. counties for numeric growth.
  • Fort Bend County picked up 24,163 residents, arriving at a total of 975,191 and positioning it at No. 8 among U.S. counties for numeric growth. Fort Bend County, the region’s second largest county based on population, is projected to break the one million-resident mark by July 2030, according to the Texas Demographics Center.

“Lower mortgage rates from 2009 to 2022 and the rise of remote work have made suburban housing more attractive, especially for families seeking affordability,” Pramod Sambidi, the Houston-Galveston Area Council’s assistant director of data analytics and research, said last year. “Additionally, suburban areas are seeing more multifamily developments than before the pandemic.”

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This article originally appeared on CultureMap.com.

5 Houston-area companies named among world's most innovative for 2026

In The Spotlight

Led by Conroe-based Hertha Metals, five organizations in the Houston area earned praise on Fast Company’s list of the World’s Most Innovative Companies of 2026.

Hertha Metals ranked No. 1 in the manufacturing category.

Last year, Hertha unveiled a single-step process for steelmaking that it says is cheaper, more energy-efficient and just as scalable as traditional steel manufacturing. It started testing the process in 2024 at a one-metric-ton-per-day pilot plant.

At the same time, Hertha announced more than $17 million in venture capital funding from investors such as Breakthrough Energy, Clean Energy Ventures, Khosla Ventures, and Pear VC.

“We’re not just reinventing steelmaking; we’re redefining what’s possible in materials, manufacturing, and national resilience,” Laureen Meroueh, founder and CEO of Hertha, said at the time.

Meroueh was also recently named to Inc. Magazine's 2026 Female Founders 500 list.

Hertha, founded in 2022, says traditional steelmaking relies on an outdated, coal-based multistep process that is costly, and contributes up to 9 percent of industrial energy use and 10 percent of global carbon emissions.

By contrast, Hertha’s method converts low-grade iron ore into molten steel or high-purity iron in one step. The company says its process is 30 percent more energy-efficient than traditional steelmaking and costs less than producing steel in China.

Last year, Hertha said it planned to break ground in 2026 on a plant capable of producing more than 9,000 metric tons of steel per year. In its next phase, the company plans to operate at 500,000 metric tons of steel production per year.

Here are Fast Company’s rankings for the four other Houston-area organizations:

  • Houston-based Vaulted Deep, No. 3 in catchall “other” category.
  • XGS Energy, No. 7 in the energy category. XGS’ proprietary solid-state geothermal system uses thermally conductive materials to deliver affordable energy anywhere hot rock is located. While Fast Company lists Houston as XGS’ headquarters, and the company has a major presence in the city, XGS is based in Palo Alto, California.
  • Houston-based residential real estate brokerage Epique Realty, No. 10 in the business services category. Epique, which bills itself as the industry’s first AI brokerage, provides a free AI toolkit for real estate agents to enhance marketing, streamline content creation, and improve engagement with clients and prospects.
  • Texas A&M University’s Nanostructured Materials Lab in College Station. The lab studies nano-structured materials to make materials lighter for the aerospace industry, improve energy storage, and enable the creation of “smart” textiles.
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This article first appeared on our sister site, EnergyCapitalHTX.com.

UH lands $11.8M for first-of-its-kind early language development study

speech funding

Researchers at the University of Houston have secured an $11.8 million grant from the National Institutes of Health to conduct a first-of-its-kind study of early language development.

Led by Elena Grigorenko, the Hugh Roy and Lillie Cranz Cullen Distinguished Professor of Psychology, and research professor Jack Fletcher, the study will follow 3,600 children aged 18 to 24 months to uncover how language skills develop at this critical stage and why some children experience delays that can influence later growth.

The NIH funding will also support the development of the new national Clinical Research Center on Developmental Language Disorders at UH, which aims to bring experts from psychology, education, health and measurement sciences to study how children learn language.

“This will be the first national study to estimate how common late talking is using a large, representative sample of Houston toddlers,” Grigorenko said in a news release. “By following these children as they grow, we hope to better understand the developmental pathways that can lead to conditions such as developmental language disorder and autism.”

UH’s team will partner with the pediatric clinic network at Texas Children’s Hospital, where children will be screened for early language development, allowing researchers to identify those who show signs of delayed speech. Next, researchers will follow the cohort through early childhood to examine how language abilities evolve and how early delays may lead to later challenges.

The Clinical Research Center on Developmental Language Disorders will be the 14th national research center established at UH, and will include researchers from multiple UH departments, as well as partners at Baylor College of Medicine and the Texas Center for Learning Disorders.

“This level of investment from the National Institutes of Health reflects the significance of this work to address a complex challenge affecting children, families and communities,” Claudia Neuhauser, vice president for research at UH, said in a news release. “By bringing together experts from multiple disciplines and partnering with major health systems across the region, the project reflects our commitment to advancing discoveries that impact our community.”