The UTHealth Behavioral Sciences Center, set to open next year, will be unlike anything in Houston. Rendering courtesy of Perkins and Will

Film and TV portrayals of psychiatric hospitals have driven a narrative based in cold, clinical rooms and unwelcoming corridors. That picture couldn't be more inaccurate when it comes to Houston's first public mental health hospital in more than three decades. Breaking stigmas and setting a new bar for design, the UTHealth Behavioral Sciences Center is set to open its doors in late 2021.

UTHealth has brought on architecture firm Perkins and Will to design the upcoming mental health facility. The behavioral health campus will be the largest facility of its kind in the United States, becoming a place to train future physicians and specialists. Located near Texas Medical Center, the space will consist of two buildings connected by a glazed bridge, surrounded by a tranquil green space.

The 220,000-square-foot facility includes 264 new inpatient beds and will provide access to mental healthcare, substance use intervention and treatment, and medical care via integrated treatment programs.

"Knowing that behavioral and mental health is a critical aspect of one's holistic well-being, our team was thoughtful in approaching each design decision through research and with the interest of promoting health," says Diana Davis, principal and managing director of the Houston studio of Perkins and Will.

Creating the calm

Rendering courtesy of Perkins and Will

Each element in the space was created with the intention of creating a peaceful environment for patients and staff. From a warm color palette to scenic views, the architecture will play a role in soothing patients and offering a relaxing space.

"We were working directly with a researcher who had done a lot of work on the impact of lighting environments for helping to establish a stronger sense of circadian rhythm in the behavioral health environment," explains Davis.

Tunable lighting fixtures that can shift to warmer hues at certain times of day were one of the intentional designs featured throughout the space.

Insomnia can arise in various mental health disorders and can even be a side effect of certain medications. According to the National Alliance on Mental Illness, approximately 50 percent of insomnia cases are related to depression, anxiety or psychological stress.

"If you've ever suffered from a little bit of insomnia, you can imagine that that probably makes the treatment process that much harder. So anything we could do as design professionals to encourage a relaxing, sleeping space was very important," says Sarah Rolfvondenbaumen, a project architect at Perkins and Will.

Like light, sound can be a crucial element in creating an ambiance. The units in the UTHealth Behavioral Sciences Center is built for 24 patients — now imagine 24 patients talking in a room. "It could get very loud," says Rolfvondenbaumen, "We focused a lot on how to reduce that sound."

Rolfvondenbaumen explained how many hospital settings use two different types of acoustics that are "necessary to make a good space to be in." Sound transmission class (STC) is the measurement of how sound travels between two different spaces, and noise reduction coefficient (NRC) is a number value that describes the average sound absorption of material.

"We used a very high in our NRC ceiling tile where applicable. . .that really helps capture the sound that is bouncing around a room and displacing it instead of reflecting it back down," says Rolfvondenbaumen. The design also changes the planes of the space, avoiding the typical square layout and giving rooms non-90 degree angles.

Perkins and Will will also be collaborating with researchers at the UTHealth Science Center to research the impact of noise reduction. By comparing the space patients are in now vs. the new building, Davis hopes to conduct "a study that would show that, hopefully, by reducing the noise that we're also able to reduce adverse events and contribute to that healing environment."

Materials matter

Rendering courtesy of Perkins and Will courtesy of Perkins and Will

Outside of choosing noise-reducing materials, Perkins and Will made a commitment to using sustainable items within the facility.

"We had a very rigorous process of selecting the interior finishes to make sure that they were good for the environment or at least good for the people who are living in the space," says Rolfvondenbaumen.

Material health was a big priority because "in trying to heal people's minds and bodies, we weren't subjecting them to materials that themselves might be carcinogens or involve an excess of pollutants in the process of being created," explains Davis.

A welcoming space

Rendering courtesy of Perkins and Will

"It was really important to us in the design to deinstitutionalize the look of the building," explains Davis, "To try to keep the height down so that it felt a little less intimidating so that it felt more like it was a part of its community."

To help patients transition from the hospital setting into the outside world, the campus includes a therapy mall. Offering opportunities for patients to practice interacting in everyday life, the therapy mall was created to be used in a multitude of ways. It can serve as a salon, boutique, fitness center, movie night spot, or music therapy space.

"One of my favorite features of the building is that the way it is designed is that the shared treatment spaces that are kind of the amenity spaces that serve multiple units are located on the ground floor and all wrap around one of the courtyards," explains Davis.

The common areas like the therapy mall and dining room feature natural light and picturesque views of the tree-filled courtyard. "We were very intentional about making sure that the key locations of therapy all had that direct communication to the outdoors and that ability to see out," says Davis.

Staff perks

Rendering courtesy of Perkins and Will

The healthcare field, especially during a pandemic, can be a stressful environment with high rates of employee burnout. The CDC has even published extensive guides for healthcare workers and first responders to help overcome the stress caused by COVID-19 and the healthcare system.

More than solely a relaxing space for patients, the UTHealth Behavioral Sciences Center is designed to make work comfortable for staff members, too. The facility's Support Pavilion holds an education center as well as break rooms, on-call sleep rooms, and a mother's room for staff.

"The Support Pavilion has its own entrance so that people coming and going are preapproved," explains Rolfvondenbaumen, "They have a badge reader so that they don't have to go through security scrutinization that the public entrance has."

Planning ahead

Rendering courtesy of Perkins and Will

Every Houstonian is, unfortunately, familiar with the city's flooding woes. The UTHealth Behavioral Sciences Center project started post-Hurricane Harvey, so flooding was undoubtedly on the mind of the Perkins and Will team.

Evacuating a healthcare building is unideal, especially a psychiatric facility. Measures were taken to prevent flooding and keep the hospital running on generator power, so patients could stay safe in the building. Just below the hospital, the facility features underground storage tanks that could fill an Olympic-sized swimming pool.

While weather can be planned for, a global pandemic is far less predictable. While the project with UTHealth was started prior to the coronavirus, the space is intentionally designed to allow patients to have flexibility throughout. Patients can choose to be in larger group settings or separate themselves into a breakout room, lending itself to social distancing guidelines.

While it's unclear whether Houston will be dealing with the COVID-19 pandemic at the close of next year, research shows the lasting mental health struggles the virus is creating. Davis foresees this project contributing "in a much more significant way" due to the unfortunate "need for care that we will have following this [pandemic] because of the mental stress and strain."

While mental and behavioral health has long-held stigmas, the UTHealth Behavioral Sciences Center will be both "welcoming and inviting," says Davis.

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7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”