3 Houston innovators to know this week

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This week's roundup of Houston innovators includes Brianna Brazle of CultureLancer, Sameer Soleja of Molecule, and Emerson Perin of Texas Heart Institute. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health care to energy tech — recently making headlines in Houston innovation.

Brianna Brazle, founder of CultureLancer

Houston founder joins DivInc's newest accelerator that supports Web3 companies with a social impact. Photo courtesy

DivInc, aTexas-based accelerator focused on helping BIPOC and female founders on their entrepreneurial journeys, announced the inaugural class for its newest accelerator. DWeb for Social Impact Accelerator, a 12-week intensive hybrid program sponsored by Filecoin Foundation for the Decentralized Web, will mentor nine companies, all of whom integrate Web3 technologies into their impact entrepreneurship.

One Houston-based startup, CultureLancer, will be participating in the program. Founded by Brianna Brazle, the career-focused platform matches students from HBCU with companies looking to hire in the fields of business development, data analysis, marketing, and operations.

“That’s a problem that has been existing and then after doing more research I learned historically about 56%, year over year, of college graduates find themselves unemployed or underemployed,” Brazle explains. “My first solution to this problem was a hybrid marketplace.” Read more.

Sameer Soleja, founder and CEO of Molecule

Sameer Soleja has expanded his company's platform. Photo courtesy of Molecule Software

Houston startup Molecule Software hopes to get a big bang out of its new platform for the energy and commodities markets. The data-as-a-lake platform, Bigbang, is available as an add-on for current Molecule customers. It enables energy trading and risk management (ETRM) and commodities trading and risk management customers to automatically import trade data from Molecule, and then merge it with various sources to conduct queries and analysis.

Molecule sells Bigbang at a monthly rate through either a yearly or multiyear contract.

“We’re seeing a growing need in the energy and commodities trading space for a turnkey data lake, as indicated by our own customers. They need real-time and automated data streaming from key systems, the ability to query the data quickly and easily, and access to the data using the analytics tools they know well,” says Sameer Soleja, founder and CEO of Molecule. Read more.

Emerson Perin, medical director of The Texas Heart Institute

Emerson Perin of the Texas Heart Institute, recently published the largest clinical trial of cell therapy for patients with chronic heart failure to-date included 580 patients at 52 sites throughout North America. Photo via texasheart.org

Emerson Perin’s end goal isn’t to treat heart failure. The medical director of The Texas Heart Institute says that he has his sights set firmly on curing the malady altogether. And, with the power of innovation and a strong team, the Houston-based cardiologist has a good chance of meeting his objective.

Perin first came to THI for fellowship training in 1988, following his residency in Miami and medical school in his birthplace of Brazil.

“This is a very special place,” the physician and researcher, whose titles also include director for THI’s Center for Clinical Research and vice president for medical affairs, tells InnovationMap. “It has a worldwide-reaching reputation. I’ve always liked research and this is a great place in terms of innovation and practicing high-level cardiology.” Read more.

Sameer Soleja, founder and CEO of Molecule, has expanded his company's platform. Photo courtesy of Molecule Software

Houston energy tech startup expands platform with new data tools

growing gains

Houston startup Molecule Software hopes to get a big bang out of its new platform for the energy and commodities markets.

The data-as-a-lake platform, Bigbang, is available as an add-on for current Molecule customers. It enables energy trading and risk management (ETRM) and commodities trading and risk management (CTRM) customers to automatically import trade data from Molecule, and then merge it with various sources to conduct queries and analysis.

Molecule sells Bigbang at a monthly rate through either a yearly or multiyear contract.

“We’re seeing a growing need in the energy and commodities trading space for a turnkey data lake, as indicated by our own customers. They need real-time and automated data streaming from key systems, the ability to query the data quickly and easily, and access to the data using the analytics tools they know well,” says Sameer Soleja, founder and CEO of Molecule.

Founded in 2012, Molecule specializes in cloud-based trading and risk management software for the energy and commodities sectors. Among the business segments that use Molecule’s software are electricity, natural gas, crude and refined products, chemicals, agricultural commodities, metals, and cryptocurrency.

“Energy and commodities markets have been undergoing a seismic shift, driven by two key factors: increasing price volatility across all commodities and a global energy transition stemming from the challenges of climate change,” Molecule says in a news release. “Given these market trends, near real-time data access and advanced trading analytics are essential for effective portfolio risk management.”

In 2021, Molecule closed a $12 million series A funding round led by Houston-based VC firm Mercury Fund. Seven years earlier, Molecule received a $1.1 million seed round from Mercury and the Houston Angel Network.

In a 2021 interview with the Houston Innovators Podcast, Soleja described how Molecule helps its customers assemble scattered data.

“The way to think about the product is if you have a brokerage account — like Robinhood, or something like that — you see how much stock you have and how much you’ve made or lost,” Soleja said.

“For companies that are trading electricity, crude oil, natural gas, and other commodities and agricultural products, they also want to see how much of each thing they have and how much they’ve made or lost. But they don’t just get to log into their brokerage account and figure it out. That’s in a lot of different places.”

The four finalists in the BIPOC-Founded Business category for the inaugural InnovationMap Awards share their best advice for their fellow founders. Photos courtesy

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This week's roundup of Houston innovators includes Sameer Soleja of Molecule, Gabriela Gerhart of The Motherhood center, and 50 Cent. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — software, education, and more — recently making headlines in Houston innovation.

Sameer Soleja, CEO of Molecule

Sameer Soleja, CEO of Molecule, joins the Houston Innovators Podcast to discuss his startup's recent fundraise — and how he's planning on being at the forefront of the evolving electricity commodities industry. Photo courtesy of Molecule

A 9-year-old software startup has been reinvigorated by fresh funds and a new opportunity to emerge as a leader in enterprise software for commodities — especially for electricity traders. Sameer Soleja, CEO of Molecule, joins the Houston Innovators Podcast to discuss the company's latest funding round — a $12 million series A.

"The commodities industry is looking really hard at electricity as the growth commodity of the 2020s — renewables and conventionally generated electricity," Soleja says. "Everybody in our client base and in the market is looking at electricity. Well, we happen to have more than have of our customer base be in electricity."

Click here to listen to the podcast and read more.

Gabriela Gerhart, founder of The Motherhood Center

Houston entrepreneur recounts journey from communism to U.S. success in new book

Gabriela Gerhart recounts her journey from communism to American success in her new book. Photo courtesy of Gabriela Gerhart

Gabriela Gerhart remembers that day, back in 1989, when her teacher walked into her classroom in Czechoslovakia and announced that communism was over. Further, she told the group that everything she'd been teaching them was a lie.

Gerhart was stunned.

"It was confusing," she tells CultureMap. "You think to yourself, 'was I fooled? Was I indoctrinated? 'You have to understand, I had no idea there was another world out there."

Gerhart, founder of The Motherhood Center on West Alabama Street unpacks those feelings and others in her new autobiography, After The Fall, a story of growing up in Central Europe under communism and following her own wanderlust to the States, where she fell in love, got married, and built a successful business.

Click here to read more.

Rapper 50 Cent really means business. 50 Cent/Twitter

Rap star and Newstonian 50 Cent is giving back to area schools in need of help. The recently relocated rapper/producer/entrepreneur/rodeo wine bidder is teaming up with the Houston Independent School District and Horizon United Group to bolster entrepreneurship programs at Kashmere, Worthing, and Wheatley high schools.

He has funded the project with a $600,000 donation, Mayor Sylvester Turner announced on May 17.

Dubbed the G-Unity Business Lab, the new program will encourage students to engage in MBA-level lessons that represent the full lifecycle of a product or concept, from idea creation, to market branding, to even running a company, a press release notes.

Click here to read more.

Sameer Soleja, CEO of Molecule, joins the Houston Innovators Podcast to discuss his startup's recent fundraise — and how he's planning on being at the forefront of the evolving electricity commodities industry. Photo courtesy of Molecule

Houston software startup to use fresh funds to become 'unquestionably the best' for the electricity industry

HOUSTON INNOVATORS PODCAST EPISODE 84

Sameer Soleja went to business school and came back into the workforce with a bit of a revelation about software for the commodities industry.

"I realized, 'wait a second, we've been making terrible software and selling it for tens of millions of dollars," Soleja, CEO of Molecule, says on this week's episode of the Houston Innovators Podcast. "We had to be able to do something better than this — technology is better than this."

Soleja founded Molecule in 2012 to address the problem. The technology isn't unfamiliar to what ardent stock traders have at their fingertips, but before these types of platforms came into the picture, commodities companies didn't have a central platform.

"The way to think about the product is if you have a brokerage account — like Robinhood, or something like that — you see how much stock you have and how much you've made or lost," Soleja says. "For companies that are trading electricity, crude oil, natural gas, and other commodities and agricultural products, they also want to see how much of each thing they have and how much they've made or lost. But they don't just get to log into their brokerage account and figure it out. That's in a lot of different places."

Lately, a couple companies have bought up some of the businesses in this sector, leaving a lot of room open up at the top. Soleja says he saw this as an opportunity and started the arduous fundraising process. Molecule closed its series A round led by Houston-based Mercury Fund this month.

The other opportunity Soleja says he saw was a new market focus on electricity — a subsector Molecule is very good at working with. About half of Molecule's clients are in this field and electricity — as opposed to oil and gas products — is full of data. Where data comes in weekly or even monthly for O&G, fresh data comes in every 15 minutes for Molecule's electrical clients.

"The commodities industry is looking really hard at electricity as the growth commodity of the 2020s — renewables and conventionally generated electricity," Soleja says. "Everybody in our client base and in the market is looking at electricity. Well, we happen to have more than have of our customer base be in electricity."

Therein lies the opportunity for Molecule, which is also interested in deploying its capital is into engineering to both meet the feature gap and exceed in places where the company is already better, Soleja explains.

"We realized, well that's the place we double down because that's where the economy is going and that's what we're good at. Let's become unquestionably the best at it," he says.

The funds will go toward company expansion. Soleja says he plans to add 50 percent to his team within the next 6 to 12 months and potentially be at 30 to 40 people in a year or two from now. Over the past nine years, Molecule has been growing organically without a centralized focus on sales and marketing.

"We are way below the benchmark for what everyone else spends on sales and marketing. So, we're going to fix that," he says.

Soleja shares more about his raise process and shares advice for his fellow startup founders on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

Molecule has closed new funding in order to focus on the energy transition. Photo via Getty Images

Houston SaaS startup closes $12M series A funding round with support from local VC

money moves

A Houston startup with a software-as-a-service platform for the energy transition has announced it closed a funding round with participation from a local venture capital.

Molecule closed its $12 million series A, and Houston-based Mercury Fund was among the company's investors. The company has a cloud-based energy trading and risk management solution for the energy industry and supports power, natural gas, crude/refined products, chemicals, agricultural commodities, softs, metals, cryptocurrencies, and more.

"We led the seed round of Molecule upon their formation and are excited to participate in their series A," says Blair Garrou, co-founder and managing director of Mercury, in a news release. "Molecule's success in the ETRM/CTRM industry, especially in relation to electricity and renewables, positions them as the company to beat for the energy transition in the 2020s."

The company will use its new funds to further build out its product as well as introduce offerings to manage renewables credits, according to the release.

"In 2020, we realized that electricity — the growth commodity of the 2020s — represented over half of Molecule's customer base, and we decided to double down," says Sameer Soleja, founder and CEO of Molecule, in the release. "We were also rated the No. 1 SaaS ETRM/CTRM vendor. With this fundraise, we have the fuel to become No. 1 SaaS platform for power and renewables, and then the market leader overall.

"Molecule is ready to power the energy transition," Soleja continues.

Molecule's last round of funding closed in November 2014. The $1.1 million seed round was supported by Mercury Fund and the Houston Angel Network.

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

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Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.