The grant is part of the selective Course & Program Grants program, which supports faculty and staff in U.S. higher education institutions to expand and strengthen STEM innovation and entrepreneurship ecosystems. Photo via shsu.edu

Three academics at Sam Houston State University have secured grant funding to support innovation and entrepreneurship at the university across science, technology, engineering, and mathematics.

Kyle Scott, assistant professor of entrepreneurship, and Bob Milner and Pamela Zelbst, co-directors of the Center for Innovation, Technology and Entrepreneurship at Sam Houston State University, have been awarded catalytic grant funding from VentureWell, a nonprofit that supports early-stage science and technology innovators. Sam Houston State University’s project was selected from a national pool of applicants.

The grant is part of the selective Course & Program Grants program, which supports faculty and staff in U.S. higher education institutions to expand and strengthen STEM innovation and entrepreneurship ecosystems. The goal for these grants is to assist with “accelerating sustainable and inclusive innovation” according to a news release.VentureWell will also help grantees in a cohort-based community of practice that will provide networking opportunities and assistance.

The grantee teams can use the funds to develop new technology transfer certificate programs for underrepresented STEM student entrepreneurs.

“VentureWell is committed to broadening pathways for science and technology innovators and the faculty supporting them—particularly those from historically underrepresented groups in the field,” said VentureWell President and CEO Phil Weilerstein in a news release . “We are excited to provide these talented grantees with resources and support to create impactful programs and learning experiences on their campuses, in their communities, and in the broader innovation and entrepreneurship ecosystem.”

Some of the projects the Center for Innovation, Technology & Entrepreneurship has recently done include a “Robohand” to help a child with Amniotic Band Syndrome (ABS).

The Greater Houston Partnership announced a new mentorship-focused initiative in the region. Photo via Houston.org

Houston organizations team up to provide mentorship, address gaps in the workforce

future of Hou

A mix of corporate and university organizations have teamed up with the Greater Houston Partnership for a new program that enables mentorship for local college students.

The GHP announced PartnerUp Houston, a new regional mentorship initiative, this week. Ten companies — including Calpine, Boston Consulting Group, and HP — have agreed to provide professional mentors and a handful of universities will offer the mentorship opportunity to students. The local universities that are signed on include Houston Christian University, Rice University, Sam Houston State University, University of Houston, and University of St. Thomas.

“Since 2017, the Partnership has facilitated collaboration between higher education leaders and the business community to strengthen the region’s talent pipeline and ensure more opportunity for Houstonians,” says Partnership Chair Thad Hill, who serves as president and CEO of Calpine, in a news release. “We believe a robust, regional mentorship program like PartnerUp will help accelerate career outcomes for students and help Houston area employers identify and cultivate great talent.”

The program is still seeking individuals and corporate partners for mentors. Those interested have until January 20 to opt in and can head online to learn more.

The program is a collaboration between the GHP and Mentor Collective, which has organized more than 250,000 successful mentorship matches since its founding in 2016.

“The United States increasingly lags behind the developed world in economic mobility," says Jackson Boyar, co-founder and CEO of Mentor Collective, in the release. "Proactively bridging these equity and skills gaps requires local employers and post-secondary institutions to collaborate on initiatives that allow students to acquire professional experiences and skills.”

“Institutions enrolling and graduating a diverse class with strong employment outcomes are those implementing holistic student support, including career mentorship," he continues. "Mentor Collective is proud to play a role in the PartnerUp Houston initiative and offer the technology needed to scale high-impact practices that drive student and economic success.”

A new UH-led program will work with energy corporations to prepare the sector's future workforce. Photo via Getty Images

University of Houston leads data science collaboration to propel energy transition

seeing green

Five Texas schools have teamed up with energy industry partners to create a program to train the sectors future workforce. At the helm of the initiative is the University of Houston.

The Data Science for Energy Transition project, which is funded through 2024 by a $1.49 million grant from the National Science Foundation, includes participation from UH, the University of Houston-Downtown, the University of Houston-Victoria, the University of Houston-Clear Lake, and Sam Houston State University.

The project will begin but introducing a five-week data science camp next summer where undergraduate and master’s level students will examine data science skills already in demand — as well as the skills that will be needed in the future as the sector navigates a shift to new technologies.

The camp will encompass computer science and programming, statistics, machine learning, geophysics and earth science, public policy, and engineering, according to a news release from UH. The project’s principal investigator is Mikyoung Jun, ConocoPhillips professor of data science at the UH College of Natural Science and Mathematics.

The new program's principal investigator is Mikyoung Jun. Photo via UH.edu

“It’s obvious that the Houston area is the capital for the energy field. We are supporting our local industries by presenting talented students from the five sponsoring universities and other Texas state universities with the essential skills to match the growing needs within those data science workforces,” Jun says in the release. “We’re planning all functions in a hybrid format so students located outside of Houston, too, can join in.”

Jun describes the camp as having a dual focus — both on the issue of energy transition to renewable sources as well as the traditional energy, because that's not being eradicated any time soon, she explains.

Also setting the program apart is the camp's prerequisites — or lack thereof. The program is open to majors in energy-related fields, such as data science or petroleum engineering, as well as wide-ranging fields of study, such as business, art, history, law, and more.

“The camp is not part of a degree program and its classes do not offer credits toward graduation, so students will continue to follow their own degree plan,” Jun says in the release. “Our goal with the summer camp is to give students a solid footing in data science and energy-related fields to help them focus on skills needed in data science workforces in energy-related companies in Houston and elsewhere. Although that may be their first career move, they may settle in other industries later. Good skills in data processing can make them wise hires for many technology-oriented organizations.”

Jun's four co-principal investigators include Pablo Pinto, professor at UH’s Hobby School of Public Affairs and director of the Center for Public Policy; Jiajia Sun, UH assistant professor of geophysics; Dvijesh Shastri, associate professor of computer science, UH-Downtown; and Yun Wan, professor of computer information systems and chair of the Computer Science Division, UH-Victoria. Eleven other faculty members from five schools will serve as senior personnel. The initiative's energy industry partners include Conoco Phillips, Schlumberger, Fugro, Quantico Energy Solutions, Shell, and Xecta Web Technologies.

The program's first iteration will select 40 students to participate in the camp this summer. Applications, which have not opened yet, will be made available online.

The Data Science for Energy Transition project is a collaboration between five schools. Image via UH.edu

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.