This week's roundup of Houston innovators includes Scott Schneider of HTX Labs, Adrienne Mangual of The Artemis Fund, and Derrick Morse of Rugged Robotics. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from virtual reality to robotics — recently making headlines in Houston innovation.

Scott Schneider, CEO and founder of HTX Labs

Scott Schneider of HTX Labs joins the Houston Innovators Podcast to discuss how his VR software is helping to train Department of Defense pilots. Photo via htxlabs.com

Over the past few years, HTX Labs — a software development startup focusing on enterprise virtual reality training software — has tripled its team and is looking to hire another 20 people to support its growth — specifically looking for sales, business development, and operational positions. All this growth is to support its work with the military, which makes up about 95 percent of the startup's focus now, says Scott Schneider, CEO and founder, on last week's Houston Innovators Podcast episode.

"In 2021, we were all about building capability and building our platform," Schneider says, "and 2022 is all about adoption. It's a land grab out there for doing what we're doing. We're trying to drive adoption within the government and outside in the commercial and private sector."

Schneider shares more on what he's focused on this year and how HTX Labs has grown alongside the Houston innovation ecosystem on the podcast episode. Click here to listen to the episode and read more.

Adrienne Mangual, vice president of finance and operations at The Artemis Fund

Adrienne Mangual has a background in finance and consulting. Photo courtesy of Artemis

The Artemis Fund is celebrating a new member of its small, but mighty team focused on funding female founders within fintech, e-commerce tech, and care-tech.

Adrienne Mangual is the new vice president of finance and operations at the firm. She has her MBA from Rice University and has worked for 15 years in finance roles at J.P. Morgan and Key Energy Services. Over the past few years, she's worked in consulting positions with startups and technology.

"This is an exciting time to join The Artemis Fund as the fund is growing and our reach is expanding and continuing to make an impact on female founders," Mangual tells InnovationMap. "I am looking forward to supporting existing and future female founders and working with Diana, Stephanie, and Leslie as part of the team making investment decisions for the fund." Click here to read more recent new hires in Houston tech.

Derrick Morse, CEO and co-founder of Rugged Robotics

Rugged Robotics has created a solution that provides construction customers with an automated layout-as-a-service tool. Image via LinkedIn

Rugged Robotics, a Houston-based robotics startup working in the commercial construction field, has closed its latest round of funding. The $9.4 million series A round was led by BOLD Capital Partners and Brick & Mortar Ventures.

“We’re building better,” says Morse, who serves as CEO, in the release. “We set out to modernize the construction industry, and to build practical solutions that solve the pain points contractors struggle with every day. We believe that layout is the ideal starting point. Layout is the beachhead for construction automation. It sits at the intersection of the digital and physical world, solves a huge problem, and unlocks the ability to deploy robotics onto job sites in a very meaningful way.” Click here to read more.

The tech solution provides construction customers with an automated layout-as-a-service tool. Image via rugged-robotics.com

Houston-based construction robotics startup raises $9.4M series A

money moves

A Houston robotics startup working in the commercial construction field has closed its latest round of funding.

Rugged Robotics Inc. announced last week that it's raised $9.4 million in its series A round led by BOLD Capital Partners and Brick & Mortar Ventures. Riot Ventures, Morpheus, and Embark — all investors in the company's 2019 seed round — also contributed, as did Consigli Construction Company and Suffolk Technologies. To date, Rugged Robotics has raised $12 million.

“We are thrilled to be part of the Rugged team,” says Maxx Bricklin, partner at BOLD Capital, in a news release. “We looked at a number of companies in the space and became convinced that the Rugged team, technology and partner ecosystem would allow Rugged to dominate and capitalize on this significant and disruptive market opportunity.”

The fresh capital, the company shares in the release, will go toward scaling operations, expanding offerings, and continuing research and development.

Founded in 2018 by construction industry veteran Derrick Morse and former NASA engineer Logan Farrell, Rugged Robotics's Mark 1 product is modernizing the construction industry. The robot addresses challenges of field layout with a “layout Roomba” that marks architectural and engineering designs directly onto unfinished concrete floors. The company's early customers include Consigli Construction Co, Suffolk Construction, and Brasfield & Gorrie.

“When Derrick and Logan first visited our office, they clearly understood the problems we face and immediately separated themselves from typical technology startups. Their focus on solving real-world problems resonates with us, and we jumped at the opportunity to engage with them,” says Mike Haseltine, vice president and head of operations at Consigli. “Seeing their robots, their layouts, and their impact is inspiring. They’ve built something that’s going to change how we build buildings.”

While the concept of an autonomous layout solution isn't new, the Rugged Robotics approach is different from the industry standard in that it has a self-contained system that "enables multi-rover deployments, one-time set-ups that span an entire floor, and print zones that extend around and behind obstructions like columns, stairs, and elevators," per the news release. The company offers its customers the technology as a layout-as-a-service model.

“We’re building better,” says Morse, who serves as CEO, in the release. “We set out to modernize the construction industry, and to build practical solutions that solve the pain points contractors struggle with every day. We believe that layout is the ideal starting point. Layout is the beachhead for construction automation. It sits at the intersection of the digital and physical world, solves a huge problem, and unlocks the ability to deploy robotics onto job sites in a very meaningful way.”

The company is growing its team, which has included the onboarding of Mason Markee, the former director of mechanical engineering of Auris Health, who joined Rugged Robotics as vice president of engineering. Prior to Auris, Markee spent eight years at NASA as a robotics engineer.

“Mason has 15 years of years of robotics experience," says Farrell, the company's CTO, in the release. "I knew him at NASA, and we’re delighted to have him onboard at Rugged. He brings tremendous experience to the table. He is familiar with the entire product life cycle, from concept generation to final commercial production. He’s seen scale, and we’re excited by the rapid growth his technical expertise and leadership experience enables.”

The company has five engineering positions listed on LinkedIn.

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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.