Ion Houston opens unique prototyping lab, names TXRX as partner

new to hou

The Ion Prototyping Lab is now open and will be powered by TXRX. Photo by Natalie Harms/InnovationMap

Midtown Houston's innovation hub has unveiled its latest building feature and named its operation partner for the space.

The Ion opened its The Ion Prototyping Lab with the announcement that Houston nonprofit TXRX Labs will be the operator of the lab. The IPL’s 6,500 square-foot space will include access to tools — such as laser cutters, CNC mills and lathes, electronics assembly equipment, and 3D printers — as well as programming, training, and support.

“The Houston community’s growing need for these services has led to our growth from a small community organization to a partnership with Houston’s leading center for innovation, The Ion,” says Roland von Kurnatowski, president of TXRX Labs, in a news release. “With our presence at The Ion and in its Prototyping Lab, we are able to join together innovative ideas and technology to create a social and collaborative space to support tomorrow’s entrepreneurs' needs and challenges.”

Founded in 2008 and based in the East End Maker Hub, TXRX Labs provides community-focused engineering and fabrication services and job training programs. The nonprofit's goal is to make Houston a major 21st-century manufacturing hub.

The new space within the 266,000 square-foot innovation hub was designed by Gensler and is "the largest open corporate and startup-aligned prototyping space in Houston," according to the release.

“As part of Gensler’s contributions to the development of The Ion, we strategically designed the Prototyping Lab to function as a dedicated space for innovators and entrepreneurs to collaborate,” says Vincent Flickinger, senior associate and design director of Gensler Houston. “The Ion Prototyping Lab is equipped with tools for prototyping robotics and other energy focused innovations and cultivates an entirely new way of doing business in a reimagined, historic building and with one of Houston’s fastest-growing innovators, TXRX. We look forward to introducing the IPL’s offerings to the public.”

The IPL is the latest opening for The Ion. Last summer, the hub, which is opened and managed by Rice Management Company, opened its coworking space. The next openings to expect are an investor studio and several restaurant concepts, including Late August, The Lymbar, and more. Common Bond On-The-Go, located on the main floor of the Ion, opened this week too.

“With its close proximity to Houston’s Central Business District and The Texas Medical Center, The Ion is thrilled to provide the Houston tech community the Prototyping Lab operated by TXRX as an essential resource for businesses,” says Jan E. Odegard, executive director of The Ion, in the release. “The Ion serves as a driver and convener of activity, while TXRX's successful model of hands-on training and technological innovation is being leveraged to jumpstart the activity of entrepreneurs, corporations, and researchers. You think it, we make it.”

Members will have daily access to the IPL from 9 am to 5 pm. The cost of the membership has not been announced, but IPL will offer grant opportunities, per the release. All members must first complete a safety and skills training course.

The East End Maker Hub, a public-private endeavor, aims to put Houston on the map for manufacturing. Photo by Natalie Harms

Photos: $38M innovative maker hub space opens in Houston's East End

new to hou

A new 300,000-square-foot innovation and manufacturing hub with a goal of creating 1,000 new companies in the next five years has officially celebrated its grand opening.

The East End Maker Hub — a $38 million public-private partnership — is anchored by TX/RX Labs, a makerspace nonprofit, and located at 6501 Navigation Blvd. So far, 25 companies have signed leasing agreements with the hub that has two of its three phases completed.

"Houston can become the next great manufacturing hub in America," says Roland von Kurnatowski, president at TX/RX Labs. "We can decrease our external reliance and increase our resilience."

The grand opening event, which was held June 3, was attended by makers, EEMH tenants and employees, and some of the local politicians that aided in making the hub a reality with grants, private funding, and more.

The EEMH has officially celebrated its grand opening. Photo by Natalie Harms

"We've always been a city of amazing innovation, whether it's been in energy, medicine, or space exploration," says Mayor Sylvester Turner. "And, we've led the world in whatever we have chosen as the pursuit of our endeavors. One thing about this city is that when we work together, we win."

"The East End Maker Hub provides an opportunity to reclaim our history of innovation and manufacturing and to ensure that the process of innovation is equitable," Turner continues. "It is not saying much to be diverse if you are not inclusive at the same time."

Through TX/RX and other tenants, the EEMH will aim to provide education, workforce development, jobs, and entrepreneurial space to innovators, students, and more.

The mission of the East End Maker Hub is to "drive advanced manufacturing by bringing together the brightest engineers, scientists, manufacturers, and makers to generate innovative advanced manufacturing solutions," according to Patrick Ezzell, president of the Urban Partnerships Community Development Corporation.

Six Houston startups recently announced their moves into the space, and the EEMH tenants represent everything from 3-D printing and unmanned aerial vehicles to vodka distilling and fragrance design.

Take a slideshow tour of the TXRX space below.

TX/RX Labs is the EEMH anchor tenant

Photo by Natalie Harms


A startup and a nonprofit makerspace have rallied to create PPE, or personal protective equipment, for local hospitals. Getty Images

Houston tech community answers the call for medical equipment amid coronavirus-caused shortages

in need of PPE

In the span of one day, the founders of Houston-based Lazarus 3D received calls from emergency room directors and physicians and vice presidents of hospitals explaining a dire need for personal protective equipment — like surgical masks and face shields — for medical professionals in the front lines of the battle against COVID-19.

"We stopped everything we were doing," says Jacques Zaneveld, co-founder of Lazarus, which makes 3D-printed human organs for surgeons to practice on. "We've moved 100 percent of our focus on developing PPE."

Now, Zaneveld with his co-founder, Smriti Agrawal Zaneveld, have manufacturing orders in for 700,000 surgical masks weekly and have designed a non-FDA approved face shield, which they have ordered a few million of. The duo has taken out a short-term loan to front the cost of the medical equipment and are now looking for the right customers to buy these new PPE products. All hospitals and medical professionals in need of supplies can head to Lazarus' website to request more info.

"Our personal feeling has been to do whatever we can do to build as many as possible," Jacques tells InnovationMap. "It's very stressful because I'm borrowing money that we don't have in order to set up these production lines."

On the other side of town, 3D printing nonprofit TXRX has reprogramed 30 of its 3D printers to make PPE. The nonprofit is working Memorial Hermann to quickly prototype and test items made with materials they can get their hands on.

The Center for Disease Control has relaxed some of the requirements for PPE in light of the crisis and shortage, and Roland von Kurnatowski, president at TX/RX Labs, says that has helped speed up their efforts. But, the biggest challenge, he says, has been to quickly get together a design and prototype for Memorial Hermann to give them feedback so that they can then produce the products.

"I think there are a lot of people out there producing devices, but I think the problem is there's not a lot of clarity around materials, quality, and acceptance. People are doing what they can with what they've got," says von Kurnatowski. "Our hope working with Memorial Hermann was to make sure we are devising and testing devices that are functional and appropriate.

TXRX is also relying on Memorial Hermann and others in the medical community to indicate which PPE devices are most needed. Currently, the nonprofit is printing 10,000 face shields for Memorial Hermann, but also has designs for N95 respirators, surgical masks, a positive air pressure respirator (or PAPR), Tyvek suit, and even a portable shield for the intubation process.

Von Kurnatowski says the Houston community can get involved by donating to TXRX's GoFundMe campaign. The 3D printing process is quick and local, but expensive and out of budget for hospitals, so TXRX is taking a loss on its products it is creating. The organization is also looking for people who might have 3D printing materials or experience to volunteer — TXRX has about 20 people working on this but hopes that number ramps up to 60 to 80 people helping out.

Crisis also brings the community together in their time of need — that's what Zaneveld says he sees happening.

"Everyone who is at all involved in the medical space in engineering in Houston is trying to put stuff out," Zaneveld says. "We're sharing information and trying to work together to support each other."

TXRX's new East End Space will allow them to provide prototyping and manufacturing services to more innovators. Courtesy of TXRX

Houston nonprofit makerspace seeking donations as it prepares to move into its new home

Calling for cash

With grants and public funds secured, Houston-based TXRX Labs as one last round of fundraising to acquire before it's ready to head full-speed ahead into its new location.

TXRX launched a $85,000 fundraising campaign to help get the organization where it needs to be before it moves into its 60,000-square-foot space in the East End Maker Hub in spring or summer of next year. The organization, along with its sister nonprofit, Urban Partnership Community Development Corp., has been selected by the city of Houston for an $18 million award and by the federal government for a $5 million innovation grant.

"In the last two weeks, we were getting close to finalizing funding for the building and came up short," says Lauren Caldarera, development director at TXRX. "We wanted to reach out to our membership at TXRX and the broader Houston community to help see if people will help support this unique offering for Houston."

In order to receive those grants, TXRX needs to submit design materials — a process that they budget to cost $325,000. (TXRX has already procured $240,000.) An anonymous donor agreed to match donations, and the organization has until the end of May to raise. Anyone can donate online.

TXRX is focused on bringing back Houston's East End as a manufacturing hub. As manufacturing jobs left the second, third, and fifth wards, it's created a need for skilled labor, middle class jobs, says Roland von Kurnatowski, executive director of TXRX.

"We're looking to bring together innovative companies in the physical innovation space into the East End and creating these middle class jobs," says von Kurnatowski. "It's a modern approach to combating economic inequalities instead of providing handouts."

TXRX is already making a dent in their mission with their smaller space. The organization has over 400 members and incubates 20 or so companies. The new space will allow TXRX to incubate almost twice that amount, work with 75 companies who need prototyping and manufacturing services, and grow their classes and educational offerings.

"Having this space is critical as Houston moves forward in creating an innovation ecosystem," Caldarera says. "We need a space for people to develop their physical prototypes, have engineers and other experts to coach and mentor them, and create more startups and innovators here."

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Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.

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