The Ion Prototyping Lab is now open and will be powered by TXRX. Photo by Natalie Harms/InnovationMap

Midtown Houston's innovation hub has unveiled its latest building feature and named its operation partner for the space.

The Ion opened its The Ion Prototyping Lab with the announcement that Houston nonprofit TXRX Labs will be the operator of the lab. The IPL’s 6,500 square-foot space will include access to tools — such as laser cutters, CNC mills and lathes, electronics assembly equipment, and 3D printers — as well as programming, training, and support.

“The Houston community’s growing need for these services has led to our growth from a small community organization to a partnership with Houston’s leading center for innovation, The Ion,” says Roland von Kurnatowski, president of TXRX Labs, in a news release. “With our presence at The Ion and in its Prototyping Lab, we are able to join together innovative ideas and technology to create a social and collaborative space to support tomorrow’s entrepreneurs' needs and challenges.”

Founded in 2008 and based in the East End Maker Hub, TXRX Labs provides community-focused engineering and fabrication services and job training programs. The nonprofit's goal is to make Houston a major 21st-century manufacturing hub.

The new space within the 266,000 square-foot innovation hub was designed by Gensler and is "the largest open corporate and startup-aligned prototyping space in Houston," according to the release.

“As part of Gensler’s contributions to the development of The Ion, we strategically designed the Prototyping Lab to function as a dedicated space for innovators and entrepreneurs to collaborate,” says Vincent Flickinger, senior associate and design director of Gensler Houston. “The Ion Prototyping Lab is equipped with tools for prototyping robotics and other energy focused innovations and cultivates an entirely new way of doing business in a reimagined, historic building and with one of Houston’s fastest-growing innovators, TXRX. We look forward to introducing the IPL’s offerings to the public.”

The IPL is the latest opening for The Ion. Last summer, the hub, which is opened and managed by Rice Management Company, opened its coworking space. The next openings to expect are an investor studio and several restaurant concepts, including Late August, The Lymbar, and more. Common Bond On-The-Go, located on the main floor of the Ion, opened this week too.

“With its close proximity to Houston’s Central Business District and The Texas Medical Center, The Ion is thrilled to provide the Houston tech community the Prototyping Lab operated by TXRX as an essential resource for businesses,” says Jan E. Odegard, executive director of The Ion, in the release. “The Ion serves as a driver and convener of activity, while TXRX's successful model of hands-on training and technological innovation is being leveraged to jumpstart the activity of entrepreneurs, corporations, and researchers. You think it, we make it.”

Members will have daily access to the IPL from 9 am to 5 pm. The cost of the membership has not been announced, but IPL will offer grant opportunities, per the release. All members must first complete a safety and skills training course.

The East End Maker Hub, a public-private endeavor, aims to put Houston on the map for manufacturing. Photo by Natalie Harms

Photos: $38M innovative maker hub space opens in Houston's East End

new to hou

A new 300,000-square-foot innovation and manufacturing hub with a goal of creating 1,000 new companies in the next five years has officially celebrated its grand opening.

The East End Maker Hub — a $38 million public-private partnership — is anchored by TX/RX Labs, a makerspace nonprofit, and located at 6501 Navigation Blvd. So far, 25 companies have signed leasing agreements with the hub that has two of its three phases completed.

"Houston can become the next great manufacturing hub in America," says Roland von Kurnatowski, president at TX/RX Labs. "We can decrease our external reliance and increase our resilience."

The grand opening event, which was held June 3, was attended by makers, EEMH tenants and employees, and some of the local politicians that aided in making the hub a reality with grants, private funding, and more.

The EEMH has officially celebrated its grand opening. Photo by Natalie Harms

"We've always been a city of amazing innovation, whether it's been in energy, medicine, or space exploration," says Mayor Sylvester Turner. "And, we've led the world in whatever we have chosen as the pursuit of our endeavors. One thing about this city is that when we work together, we win."

"The East End Maker Hub provides an opportunity to reclaim our history of innovation and manufacturing and to ensure that the process of innovation is equitable," Turner continues. "It is not saying much to be diverse if you are not inclusive at the same time."

Through TX/RX and other tenants, the EEMH will aim to provide education, workforce development, jobs, and entrepreneurial space to innovators, students, and more.

The mission of the East End Maker Hub is to "drive advanced manufacturing by bringing together the brightest engineers, scientists, manufacturers, and makers to generate innovative advanced manufacturing solutions," according to Patrick Ezzell, president of the Urban Partnerships Community Development Corporation.

Six Houston startups recently announced their moves into the space, and the EEMH tenants represent everything from 3-D printing and unmanned aerial vehicles to vodka distilling and fragrance design.

Take a slideshow tour of the TXRX space below.

TX/RX Labs is the EEMH anchor tenant

Photo by Natalie Harms


A startup and a nonprofit makerspace have rallied to create PPE, or personal protective equipment, for local hospitals. Getty Images

Houston tech community answers the call for medical equipment amid coronavirus-caused shortages

in need of PPE

In the span of one day, the founders of Houston-based Lazarus 3D received calls from emergency room directors and physicians and vice presidents of hospitals explaining a dire need for personal protective equipment — like surgical masks and face shields — for medical professionals in the front lines of the battle against COVID-19.

"We stopped everything we were doing," says Jacques Zaneveld, co-founder of Lazarus, which makes 3D-printed human organs for surgeons to practice on. "We've moved 100 percent of our focus on developing PPE."

Now, Zaneveld with his co-founder, Smriti Agrawal Zaneveld, have manufacturing orders in for 700,000 surgical masks weekly and have designed a non-FDA approved face shield, which they have ordered a few million of. The duo has taken out a short-term loan to front the cost of the medical equipment and are now looking for the right customers to buy these new PPE products. All hospitals and medical professionals in need of supplies can head to Lazarus' website to request more info.

"Our personal feeling has been to do whatever we can do to build as many as possible," Jacques tells InnovationMap. "It's very stressful because I'm borrowing money that we don't have in order to set up these production lines."

On the other side of town, 3D printing nonprofit TXRX has reprogramed 30 of its 3D printers to make PPE. The nonprofit is working Memorial Hermann to quickly prototype and test items made with materials they can get their hands on.

The Center for Disease Control has relaxed some of the requirements for PPE in light of the crisis and shortage, and Roland von Kurnatowski, president at TX/RX Labs, says that has helped speed up their efforts. But, the biggest challenge, he says, has been to quickly get together a design and prototype for Memorial Hermann to give them feedback so that they can then produce the products.

"I think there are a lot of people out there producing devices, but I think the problem is there's not a lot of clarity around materials, quality, and acceptance. People are doing what they can with what they've got," says von Kurnatowski. "Our hope working with Memorial Hermann was to make sure we are devising and testing devices that are functional and appropriate.

TXRX is also relying on Memorial Hermann and others in the medical community to indicate which PPE devices are most needed. Currently, the nonprofit is printing 10,000 face shields for Memorial Hermann, but also has designs for N95 respirators, surgical masks, a positive air pressure respirator (or PAPR), Tyvek suit, and even a portable shield for the intubation process.

Von Kurnatowski says the Houston community can get involved by donating to TXRX's GoFundMe campaign. The 3D printing process is quick and local, but expensive and out of budget for hospitals, so TXRX is taking a loss on its products it is creating. The organization is also looking for people who might have 3D printing materials or experience to volunteer — TXRX has about 20 people working on this but hopes that number ramps up to 60 to 80 people helping out.

Crisis also brings the community together in their time of need — that's what Zaneveld says he sees happening.

"Everyone who is at all involved in the medical space in engineering in Houston is trying to put stuff out," Zaneveld says. "We're sharing information and trying to work together to support each other."

TXRX's new East End Space will allow them to provide prototyping and manufacturing services to more innovators. Courtesy of TXRX

Houston nonprofit makerspace seeking donations as it prepares to move into its new home

Calling for cash

With grants and public funds secured, Houston-based TXRX Labs as one last round of fundraising to acquire before it's ready to head full-speed ahead into its new location.

TXRX launched a $85,000 fundraising campaign to help get the organization where it needs to be before it moves into its 60,000-square-foot space in the East End Maker Hub in spring or summer of next year. The organization, along with its sister nonprofit, Urban Partnership Community Development Corp., has been selected by the city of Houston for an $18 million award and by the federal government for a $5 million innovation grant.

"In the last two weeks, we were getting close to finalizing funding for the building and came up short," says Lauren Caldarera, development director at TXRX. "We wanted to reach out to our membership at TXRX and the broader Houston community to help see if people will help support this unique offering for Houston."

In order to receive those grants, TXRX needs to submit design materials — a process that they budget to cost $325,000. (TXRX has already procured $240,000.) An anonymous donor agreed to match donations, and the organization has until the end of May to raise. Anyone can donate online.

TXRX is focused on bringing back Houston's East End as a manufacturing hub. As manufacturing jobs left the second, third, and fifth wards, it's created a need for skilled labor, middle class jobs, says Roland von Kurnatowski, executive director of TXRX.

"We're looking to bring together innovative companies in the physical innovation space into the East End and creating these middle class jobs," says von Kurnatowski. "It's a modern approach to combating economic inequalities instead of providing handouts."

TXRX is already making a dent in their mission with their smaller space. The organization has over 400 members and incubates 20 or so companies. The new space will allow TXRX to incubate almost twice that amount, work with 75 companies who need prototyping and manufacturing services, and grow their classes and educational offerings.

"Having this space is critical as Houston moves forward in creating an innovation ecosystem," Caldarera says. "We need a space for people to develop their physical prototypes, have engineers and other experts to coach and mentor them, and create more startups and innovators here."

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Texas booms as No. 3 best state to start a business right now

Innovation Starts Here

High employment growth and advantageous entrepreneurship rates have led Texas into a triumphant No. 3 spot in WalletHub's ranking of "Best and Worst States to Start a Business" for 2026.

Texas bounced back into the No. 3 spot nationally for the first time since 2023. After dropping into 8th place in 2024, the state hustled into No. 4 last year.

Ever year, WalletHub compares all 50 states based on their business environment, costs, and access to financial resources to determine the best places for starting a business. The study analyzes 25 relevant metrics to determine the rankings, such as labor costs, office space affordability, financial accessibility, the number of startups per capita, and more.

When about half of all new businesses don't last more than five years, finding the right environment for a startup is vital for long-term success, the report says.

Here's how Texas ranked across the three main categories in the study:

  • No. 1 – Business environment
  • No. 11 – Access to resources
  • No. 34 – Business costs

The state boasts the 10th highest entrepreneurship rates nationwide, and it has the 11th-highest share of fast-growing firms. WalletHub also noted that more than half (53 percent) of all Texas businesses are located in "strong clusters," which suggests they are more likely to be successful long-term.

"Clusters are interconnected businesses that specialize in the same field, and 'strong clusters' are ones that are in the top 25 percent of all regions for their particular specialization," the report said. "If businesses fit into one of these clusters, they will have an easier time getting the materials they need, and can tap into an existing customer base. To some degree, it might mean more competition, though."

Texas business owners should also keep their eye on Houston, which was recently ranked the 7th best U.S. city for starting a new business, and it was dubbed one of the top-10 tech hubs in North America. Workers in Texas are the "third-most engaged" in the country, the study added, a promising attribute for employers searching for the right place to begin their next business venture.

"Business owners in Texas benefit from favorable conditions, as the state has the third-highest growth in working-age population and the third-highest employment growth in the country, too," the report said.

The top 10 best states for starting a business in 2026 are:

  • No. 1 – Florida
  • No. 2 – Utah
  • No. 3 – Texas
  • No. 4 – Oklahoma
  • No. 5 – Idaho
  • No. 6 – Mississippi
  • No. 7 – Georgia
  • No. 8 – Indiana
  • No. 9 – Nevada
  • No. 10 – California
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This article originally appeared on CultureMap.com.

Houston lab-test startup seeks $1M for nationwide expansion

Testing Access

Health care industry veteran Jim Gebhart knew there had to be a better way for patients to access lab services, especially those with high health insurance deductibles or no insurance at all.

“This challenge became deeply personal when a close family member developed a serious illness, and we struggled to secure prompt appointments,” Gebhart tells InnovationMap. “It’s incredibly frustrating when a loved one cannot receive timely care simply because of provider shortages or the limited capacity of traditional clinics.”

Driven by the desire to knock down lab-test barriers, Gebhart founded Houston-based TheLabCafe.com in 2024. The platform provides access to low-cost medical tests without requiring patients to carry health insurance. TheLabCafe serves patients in six states: Texas, Georgia, Louisiana, Nevada, New Mexico and Oklahoma. Gebhart, the startup’s CEO, says that by the end of March, LabCafe will be offering services in 20 more states and the District of Columbia.

Gebhart has spent more than 30 years in the lab industry. His career includes stints at Austin-based Clinical Pathology Laboratories, Ohio’s Cleveland Clinic Laboratories and Secaucus, New Jersey-based Quest Diagnostics.

“Since nearly 80 percent of disease diagnoses rely on laboratory testing, I decided to leverage my background to create a more accessible, self-directed process for individuals to order blood and urine tests on their own terms — when and where they need them,” says Gebhart.

So far, Gebhart is self-funding the startup. But he plans to seek $700,000 to $1 million in outside investments in late 2026 to support the nationwide expansion and the introduction of more services.

TheLabCafe contracts with labs for an array of tests, such as cholesterol, hepatitis, metabolic, testosterone, thyroid and sexually transmitted infection (STI) tests. A cholesterol test obtained through TheLabCafe might cost $29, compared with a typical cost of perhaps $39 to $59 without insurance.

A health care professional reviews every test, both when the test is ordered and when the results are delivered, often within 24 hours. After receiving test results, a patient can schedule a virtual visit with a health care professional to go over the findings and learn potential treatment options.

Gebhart says TheLabCafe particularly benefits uninsured patients, including those in Texas. Among the states, Texas has the highest rate of uninsured residents. U.S. Census Bureau data shows 21.6 percent of adults and 13.6 percent of children in Texas lacked health insurance in 2024.

“Uninsured patients often pay the highest prices in the health care system,” Gebhart explains. “We address this by offering straightforward pricing and convenient access to testing without requiring insurance.”

“Our rates are intentionally set to remain affordable, helping individuals take a proactive approach to their health,” he adds. “Regular testing enables people to identify potential health issues early and track their progress as they make lifestyle changes. Ultimately, you can’t measure improvement without data — and laboratory results provide that data.”

Houston geothermal startup secures $97M Series B for next-gen power

fresh funding

Houston-based geothermal energy startup Sage Geosystems has closed its Series B fundraising round and plans to use the money to launch its first commercial next-generation geothermal power generation facility.

Ormat Technologies and Carbon Direct Capital co-led the $97 million round, according to a press release from Sage. Existing investors Exa, Nabors, alfa8, Arch Meredith, Abilene Partners, Cubit Capital and Ignis H2 Energy also participated, as well as new investors SiteGround Capital and The UC Berkeley Foundation’s Climate Solutions Fund.

The new geothermal power generation facility will be located at one of Ormat Technologies' existing power plants. The Nevada-based company has geothermal power projects in the U.S. and numerous other countries around the world. The facility will use Sage’s proprietary pressure geothermal technology, which extracts geothermal heat energy from hot dry rock, an abundant geothermal resource.

“Pressure geothermal is designed to be commercial, scalable and deployable almost anywhere,” Cindy Taff, CEO of Sage Geosystems, said in the news release. “This Series B allows us to prove that at commercial scale, reflecting strong conviction from partners who understand both the urgency of energy demand and the criticality of firm power.”

Sage reports that partnering with the Ormat facility will allow it to market and scale up its pressure geothermal technology at a faster rate.

“This investment builds on the strong foundation we’ve established through our commercial agreement and reinforces Ormat’s commitment to accelerating geothermal development,” Doron Blachar, CEO of Ormat Technologies, added in the release. “Sage’s technical expertise and innovative approach are well aligned with Ormat’s strategy to move faster from concept to commercialization. We’re pleased to take this natural next step in a partnership we believe strongly in.”

In 2024, Sage agreed to deliver up to 150 megawatts of new geothermal baseload power to Meta, the parent company of Facebook. At the time, the companies reported that the project's first phase would aim to be operating in 2027.

The company also raised a $17 million Series A, led by Chesapeake Energy Corp., in 2024.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.