The Ion Prototyping Lab is now open and will be powered by TXRX. Photo by Natalie Harms/InnovationMap

Midtown Houston's innovation hub has unveiled its latest building feature and named its operation partner for the space.

The Ion opened its The Ion Prototyping Lab with the announcement that Houston nonprofit TXRX Labs will be the operator of the lab. The IPL’s 6,500 square-foot space will include access to tools — such as laser cutters, CNC mills and lathes, electronics assembly equipment, and 3D printers — as well as programming, training, and support.

“The Houston community’s growing need for these services has led to our growth from a small community organization to a partnership with Houston’s leading center for innovation, The Ion,” says Roland von Kurnatowski, president of TXRX Labs, in a news release. “With our presence at The Ion and in its Prototyping Lab, we are able to join together innovative ideas and technology to create a social and collaborative space to support tomorrow’s entrepreneurs' needs and challenges.”

Founded in 2008 and based in the East End Maker Hub, TXRX Labs provides community-focused engineering and fabrication services and job training programs. The nonprofit's goal is to make Houston a major 21st-century manufacturing hub.

The new space within the 266,000 square-foot innovation hub was designed by Gensler and is "the largest open corporate and startup-aligned prototyping space in Houston," according to the release.

“As part of Gensler’s contributions to the development of The Ion, we strategically designed the Prototyping Lab to function as a dedicated space for innovators and entrepreneurs to collaborate,” says Vincent Flickinger, senior associate and design director of Gensler Houston. “The Ion Prototyping Lab is equipped with tools for prototyping robotics and other energy focused innovations and cultivates an entirely new way of doing business in a reimagined, historic building and with one of Houston’s fastest-growing innovators, TXRX. We look forward to introducing the IPL’s offerings to the public.”

The IPL is the latest opening for The Ion. Last summer, the hub, which is opened and managed by Rice Management Company, opened its coworking space. The next openings to expect are an investor studio and several restaurant concepts, including Late August, The Lymbar, and more. Common Bond On-The-Go, located on the main floor of the Ion, opened this week too.

“With its close proximity to Houston’s Central Business District and The Texas Medical Center, The Ion is thrilled to provide the Houston tech community the Prototyping Lab operated by TXRX as an essential resource for businesses,” says Jan E. Odegard, executive director of The Ion, in the release. “The Ion serves as a driver and convener of activity, while TXRX's successful model of hands-on training and technological innovation is being leveraged to jumpstart the activity of entrepreneurs, corporations, and researchers. You think it, we make it.”

Members will have daily access to the IPL from 9 am to 5 pm. The cost of the membership has not been announced, but IPL will offer grant opportunities, per the release. All members must first complete a safety and skills training course.

The East End Maker Hub, a public-private endeavor, aims to put Houston on the map for manufacturing. Photo by Natalie Harms

Photos: $38M innovative maker hub space opens in Houston's East End

new to hou

A new 300,000-square-foot innovation and manufacturing hub with a goal of creating 1,000 new companies in the next five years has officially celebrated its grand opening.

The East End Maker Hub — a $38 million public-private partnership — is anchored by TX/RX Labs, a makerspace nonprofit, and located at 6501 Navigation Blvd. So far, 25 companies have signed leasing agreements with the hub that has two of its three phases completed.

"Houston can become the next great manufacturing hub in America," says Roland von Kurnatowski, president at TX/RX Labs. "We can decrease our external reliance and increase our resilience."

The grand opening event, which was held June 3, was attended by makers, EEMH tenants and employees, and some of the local politicians that aided in making the hub a reality with grants, private funding, and more.

The EEMH has officially celebrated its grand opening. Photo by Natalie Harms

"We've always been a city of amazing innovation, whether it's been in energy, medicine, or space exploration," says Mayor Sylvester Turner. "And, we've led the world in whatever we have chosen as the pursuit of our endeavors. One thing about this city is that when we work together, we win."

"The East End Maker Hub provides an opportunity to reclaim our history of innovation and manufacturing and to ensure that the process of innovation is equitable," Turner continues. "It is not saying much to be diverse if you are not inclusive at the same time."

Through TX/RX and other tenants, the EEMH will aim to provide education, workforce development, jobs, and entrepreneurial space to innovators, students, and more.

The mission of the East End Maker Hub is to "drive advanced manufacturing by bringing together the brightest engineers, scientists, manufacturers, and makers to generate innovative advanced manufacturing solutions," according to Patrick Ezzell, president of the Urban Partnerships Community Development Corporation.

Six Houston startups recently announced their moves into the space, and the EEMH tenants represent everything from 3-D printing and unmanned aerial vehicles to vodka distilling and fragrance design.

Take a slideshow tour of the TXRX space below.

TX/RX Labs is the EEMH anchor tenant

Photo by Natalie Harms


A startup and a nonprofit makerspace have rallied to create PPE, or personal protective equipment, for local hospitals. Getty Images

Houston tech community answers the call for medical equipment amid coronavirus-caused shortages

in need of PPE

In the span of one day, the founders of Houston-based Lazarus 3D received calls from emergency room directors and physicians and vice presidents of hospitals explaining a dire need for personal protective equipment — like surgical masks and face shields — for medical professionals in the front lines of the battle against COVID-19.

"We stopped everything we were doing," says Jacques Zaneveld, co-founder of Lazarus, which makes 3D-printed human organs for surgeons to practice on. "We've moved 100 percent of our focus on developing PPE."

Now, Zaneveld with his co-founder, Smriti Agrawal Zaneveld, have manufacturing orders in for 700,000 surgical masks weekly and have designed a non-FDA approved face shield, which they have ordered a few million of. The duo has taken out a short-term loan to front the cost of the medical equipment and are now looking for the right customers to buy these new PPE products. All hospitals and medical professionals in need of supplies can head to Lazarus' website to request more info.

"Our personal feeling has been to do whatever we can do to build as many as possible," Jacques tells InnovationMap. "It's very stressful because I'm borrowing money that we don't have in order to set up these production lines."

On the other side of town, 3D printing nonprofit TXRX has reprogramed 30 of its 3D printers to make PPE. The nonprofit is working Memorial Hermann to quickly prototype and test items made with materials they can get their hands on.

The Center for Disease Control has relaxed some of the requirements for PPE in light of the crisis and shortage, and Roland von Kurnatowski, president at TX/RX Labs, says that has helped speed up their efforts. But, the biggest challenge, he says, has been to quickly get together a design and prototype for Memorial Hermann to give them feedback so that they can then produce the products.

"I think there are a lot of people out there producing devices, but I think the problem is there's not a lot of clarity around materials, quality, and acceptance. People are doing what they can with what they've got," says von Kurnatowski. "Our hope working with Memorial Hermann was to make sure we are devising and testing devices that are functional and appropriate.

TXRX is also relying on Memorial Hermann and others in the medical community to indicate which PPE devices are most needed. Currently, the nonprofit is printing 10,000 face shields for Memorial Hermann, but also has designs for N95 respirators, surgical masks, a positive air pressure respirator (or PAPR), Tyvek suit, and even a portable shield for the intubation process.

Von Kurnatowski says the Houston community can get involved by donating to TXRX's GoFundMe campaign. The 3D printing process is quick and local, but expensive and out of budget for hospitals, so TXRX is taking a loss on its products it is creating. The organization is also looking for people who might have 3D printing materials or experience to volunteer — TXRX has about 20 people working on this but hopes that number ramps up to 60 to 80 people helping out.

Crisis also brings the community together in their time of need — that's what Zaneveld says he sees happening.

"Everyone who is at all involved in the medical space in engineering in Houston is trying to put stuff out," Zaneveld says. "We're sharing information and trying to work together to support each other."

TXRX's new East End Space will allow them to provide prototyping and manufacturing services to more innovators. Courtesy of TXRX

Houston nonprofit makerspace seeking donations as it prepares to move into its new home

Calling for cash

With grants and public funds secured, Houston-based TXRX Labs as one last round of fundraising to acquire before it's ready to head full-speed ahead into its new location.

TXRX launched a $85,000 fundraising campaign to help get the organization where it needs to be before it moves into its 60,000-square-foot space in the East End Maker Hub in spring or summer of next year. The organization, along with its sister nonprofit, Urban Partnership Community Development Corp., has been selected by the city of Houston for an $18 million award and by the federal government for a $5 million innovation grant.

"In the last two weeks, we were getting close to finalizing funding for the building and came up short," says Lauren Caldarera, development director at TXRX. "We wanted to reach out to our membership at TXRX and the broader Houston community to help see if people will help support this unique offering for Houston."

In order to receive those grants, TXRX needs to submit design materials — a process that they budget to cost $325,000. (TXRX has already procured $240,000.) An anonymous donor agreed to match donations, and the organization has until the end of May to raise. Anyone can donate online.

TXRX is focused on bringing back Houston's East End as a manufacturing hub. As manufacturing jobs left the second, third, and fifth wards, it's created a need for skilled labor, middle class jobs, says Roland von Kurnatowski, executive director of TXRX.

"We're looking to bring together innovative companies in the physical innovation space into the East End and creating these middle class jobs," says von Kurnatowski. "It's a modern approach to combating economic inequalities instead of providing handouts."

TXRX is already making a dent in their mission with their smaller space. The organization has over 400 members and incubates 20 or so companies. The new space will allow TXRX to incubate almost twice that amount, work with 75 companies who need prototyping and manufacturing services, and grow their classes and educational offerings.

"Having this space is critical as Houston moves forward in creating an innovation ecosystem," Caldarera says. "We need a space for people to develop their physical prototypes, have engineers and other experts to coach and mentor them, and create more startups and innovators here."

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10 promising Houston startups that made headlines in 2025

year in review

Editor's note: As we reflect on 2025, we're looking back at the stories and startups that made waves in Houston's innovation scene. These 10 startups reached memorable milestones, won prestigious awards, found creative solutions, and disrupted their industries.

Persona AI: Houston humanoid robotics startup inks new deal to deploy its rugged robots

A concept design rendering of Persona AI's humanoid robot. The company is expanding at the Ion and plans to deliver prototype humanoids by the end of 2026 for complex shipyard welding tasks. Rendering courtesy Persona AI.

Persona AI is building modularized humanoid robots that aim to deliver continuous, round-the-clock productivity and skilled labor for "dull, dirty, dangerous, and declining" jobs. The company was founded by Houston entrepreneur Nicolaus Radford, who serves as CEO, along with CTO Jerry Pratt and COO Jide Akinyode. It raised $42 million in pre-seed funding this year and is developing its prototype of a robot-welder for Hyundai's shipbuilding division, which it plans to unveil in 2026. The company won in the Deep Tech Business category at this year's Houston Innovation Awards. Continue reading.

Rheom Materials: Houston startup unveils its innovative leather alternative at the rodeo

Rheom Materials presented its bio-based alternative, Shorai, a 93 percent bio-based leather, at the rodeo and plans to scale it up this year. Photos courtesy Rheom Materials

Rheom Materials presented its scalable, bio-based alternative known as Shorai, a 93 percent bio-based leather, through two custom, western-inspired outfits that showed off cowboy flair through a sustainable lens at the Houston Livestock Show and Rodeo earlier this year.

Next up, the company said it aimed to scale production of Shorai, the Japanese word for “future,” at a competitive price point, while also reducing its carbon footprint by 80 percent when compared to synthetic leather. The company also made a large-scale production partnership with a thermoplastic extrusion and lamination company, Bixby International, this year. Continue reading.

Koda Health: Houston digital health platform Koda closes $7 million funding round

Tatiana Fofanova and Dr. Desh Mohan, founders of Koda Health, which recently closed a $7 million series A. Photo courtesy Koda Health.

Houston-based digital advance care planning company Koda Health closed an oversubscribed $7 million series A funding round this year. The round, led by Evidenced, with participation from Mudita Venture Partners, Techstars and Texas Medical Center, will allow the company to scale operations and expand engineering, clinical strategy and customer success. Koda Health, saw major growth this year by integrating its end-of-life care planning platform with Dallas-based Guidehealth in April and with Epic Systems in July. The company won the Health Tech Business category at the 2025 Houston Innovation Awards. Continue reading.

Veloci Running: Student-led startup runs away with prestigious prize at Rice competition

The H. Albert Napier Rice Launch Challenge awarded $100,000 in equity-free funding to student-led startups, including first-place finisher Veloci Running. Photo courtesy of Rice University.

Veloci Running took home the first-place prize and $50,000 at the annual Liu Idea Lab for Innovation and Entrepreneurship's H. Albert Napier Rice Launch Challenge. The company was founded by Tyler Strothman, a former track and field athlete and senior at Rice, majoring in sport management. Inspired by the foot pain he suffered due to the narrow toe boxes in his running shoes, Strothman decided to create a naturally shaped shoe designed to relieve lower leg tightness and absorb impact. Additional prize winners included SteerBio, Kinnections, Labshare and several others. Continue reading.

Square Robot Inc.: Houston robotics co. unveils new robot that can handle extreme temperatures

The new robot eliminates the need for humans to enter dangerous and toxic environments. Photo courtesy of Square Robot

Houston- and Boston-based Square Robot Inc.'s newest tank inspection robot became commercially available and certified to operate at extreme temperatures this fall. The new robot, known as the SR-3HT, can operate from 14°F to 131°F, representing a broader temperature range than previous models in the company's portfolio. According to the company, its previous temperature range reached 32°F to 104°F. The company also announced a partnership with downstream and midstream energy giant Marathon Petroleum Corp. (NYSE: MPC) last month. Continue reading.

Bot Auto: Houston autonomous trucking co. completes first test run without human intervention

Bot Auto completed its first test run without human assistance in Houston. Photo courtesy Bot Auto.

Houston-based Bot Auto, an autonomous trucking company, completed its first test run without human assistance earlier this year. Bot Auto conducted the test in Houston. The transportation-as-a-service startup added that this milestone “serves as a validation benchmark, demonstrating the maturity and safety of Bot Auto’s autonomy stack and test protocols.” This summer, founder Xiaodi Hou told the Front Lines podcast that Bot Auto had raised more than $45 million. Continue reading.

Nomad: Screen-free hiking app developed in Houston earns 'Best of the Best' award

NOMAD aims to help hikers stay in the moment while still utilizing technology. Photo courtesy UH.

An AI-powered, screen-free hiking system developed by Varshini Chouthri, a recent industrial design graduate from the University of Houston, received this year's Red Dot’s “Best of the Best” award, which recognizes the top innovative designs around the world. Known as NOMAD, the system aims to help users stay in the moment while still utilizing technology. Continue reading.

Little Place Labs, Helix Earth, Tempest Droneworx: Houston startups win big at SXSW 2025 pitch competition

Two Houston startups won the SXSW Pitch showcase in their respective categories. Photo via Getty Images

Houston had a strong showing at the SXSW Pitch showcase in Austin this year, with several local startups claiming top prizes in their respective categories.

Little Place Labs, a Houston space data startup, won the Security, GovTech & Space competition. Clean-tech company Helix Earth, which spun out of Rice University and was incubated at Greentown Labs, won in the Smart Cities, Transportation & Sustainability contest. Tempest Droneworx, a Houston-based company that provides real-time intelligence collected through drones, robots and sensors, won the Best Speed Pitch award. Continue reading.

6 Houstonians named to prestigious national group of inventors

top honor

Six Houston scientists and innovation leaders have been named to the National Academy of Inventors’ newest class of fellows. The award is the highest professional distinction awarded to academic inventors by the NAI.

The 2025 class is made up of 169 fellows who hold more than 5,300 U.S. patents, according to the organization. The group hails from 127 institutions across 40 U.S. states.

The Houston-based inventors are leading fields from AI to chemistry to cancer research.

“NAI Fellows are a driving force within the innovation ecosystem, and their contributions across scientific disciplines are shaping the future of our world,” Paul R. Sanberg, president of the National Academy of Inventors, said in a news release. “We are thrilled to welcome this year’s class of Fellows to the Academy. They are truly an impressive cohort, and we look forward to honoring them at our 15th Annual Conference in Los Angeles next year.”

The 2025 list of Houston-based fellows includes:

  • Vineet Gupta, Vice President for Innovation, Technology Development and Transfer at the University of Texas Medical Branch
  • Eva Harth, chemistry professor at the University of Houston
  • Dr. Raghu Kalluri, Professor and Chairman of the Department of Cancer Biology at The University of Texas MD Anderson Cancer Center
  • Sanjoy Paul, Executive Director of Rice Nexus and AI Houston and Associate Vice President for Technology Development at Rice University
  • Dr. Jochen Reiser, President of the University of Texas Medical Branch and CEO of UTMB Health System
  • Todd Rosengart, Professor and Chair of the Department of Surgery at Baylor College of Medicine

"It is a great honor to be named a Fellow of the NAI. It is deeply gratifying to know that the work my students and I do — the daily push, often in small steps — is seen and recognized," Harth added in a news release from UH.

The 2025 fellows will be honored and presented with their medals by a senior official of the United States Patent and Trademark Office at the NAI Annual Conference this summer in Los Angeles.