A Houston-based team of scientists and students have developed a low-cost ventilator. Photo courtesy of Rice University

As the COVID-19 case numbers continue to grow, hospitals around the world are either experiencing or expecting a shortage of ventilation units. In Houston, a team of students and staff at Rice University have designed a solution.

Along with Canadian global health design firm, Metric Technologies, the Rice team has developed an automated bag valve mask ventilator that can be crafted for less than $300. Moreover, the team expects to share the designs so that these low-cost machines can be produced everywhere.

The project is being called Take a Breatherand was inspired by an early prototype that a group of engineering seniors developed in 2019 at Rice's Brown School of Engineering'sOshman Engineering Design Kitchen, or OEDK. The idea was to take a bag valve mask, which medical professionals use manually by squeezing with their hands, and create a device that can instead compress the bag automatically.

The parts of the device are largely created via 3D printing and laser cut, according to a press release from Rice, and only took around a week to prototype. While the original project was created to help emergency medicine professionals using a manual ventilator, the device is very relevant in the current coronavirus crisis.

"The immediate goal is a device that works well enough to keep noncritical COVID-19 patients stable and frees up larger ventilators for more critical patients," says Amy Kavalewitz, executive director of the OEDK, in the release.

As principal at Metric Technologies, Dr. Rohith Malya, who is assistant professor of emergency medicine at Baylor College of Medicine and an adjunct assistant professor of bioengineering at Rice, saw the growing need for for automated ventilator masks in emergency medicine.

"This is a clinician-informed end-to-end design that repurposes the existing BVM global inventory toward widespread and safe access to mechanical ventilation," Malya says in the release.

According to Malya, more than 100 million bag valve masks are produced annually. The designed device, which can work with these bags, has been named the ApolloBVM — a nod to when President John F. Kennedy announced from the Rice campus that it was his mission to get America to the moon.

"This project appeals to our ingenuity, it's a Rice-based project and it's for all of humanity," he says in the release. "And we're on an urgent timescale. We decided to throw it all on the table and see how far we go."

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Houston medical device startup implants artificial heart in first human patient

big win

Heart health tech company BiVACOR and The Texas Heart Institute announced that they successfully implanted the company's first Total Artificial Heart in a human at Baylor St. Luke’s Medical Center in the TMC.

The milestone is part of an FDA-approved early feasibility study that will test the safety and performance of the TAH device, which is based on a magnetically levitated rotor that takes over functions of a failing heart while a patient is awaiting a heart transplant, according to a statement from the organizations.

The "bridge-to-transplant" device could support an active adult male, as well as many women and children suffering from severe biventricular heart failure or univentricular heart failure.

"With heart failure remaining a leading cause of mortality globally, the BiVACOR TAH offers a beacon of hope for countless patients awaiting a heart transplant,” Dr. Joseph Rogers, president and CEO of THI and national principal investigator on the research, says in a statement. “We are proud to be at the forefront of this medical breakthrough, working alongside the dedicated teams at BiVACOR, Baylor College of Medicine, and Baylor St. Luke’s Medical Center to transform the future of heart failure therapy for this vulnerable population.”

BiVACOR received approval from the FDA for the early feasibility study in late 2023 and has four other patients enrolled in the study. At the time the study was approved, 10 hospitals were enrolled as possible sites.

“I’m incredibly proud to witness the successful first-in-human implant of our TAH. This achievement would not have been possible without the courage of our first patient and their family, the dedication of our team, and our expert collaborators at The Texas Heart Institute ... our TAH brings us one step closer to providing a desperately needed option for people with end-stage heart failure who require support while waiting for a heart transplant. I look forward to continuing the next phase of our clinical trial,” Daniel Timms, PhD, founder and CTO of BiVACOR, adds.

About 100,000 patients suffering from severe heart failure could benefit from BiVACOR’s artificial heart, the company says. Globally, only about 6,000 heart transplants are performed each year, while 26 million people worldwide are affected by heart failure.

BiVACOR was founded in 2008 and maintains its headquarters in Houston, along with offices in Huntington Beach, California, and Brisbane, Australia.

To date, the company has raised nearly $50.8 million, according to CB Insights. The company raised $18 million in 2023, and $22 million in 2021.

Earlier this year, BiVACOR named a new CEO in Jim Dillon, a longtime executive in the medical device sector.

Last summer, Rogers joined the Houston Innovators Podcast to share his excitement with THI's innovations.


Here's how much it takes to earn a top 1 percent salary in Texas

wealthy lifestyle

With two Houston-area neighbors cashing in among the most wealthy suburbs in America, Houstonians may be wondering how much money they need to make to secure a place in the top one percent of earners. According to a new study from SmartAsset, the pre-tax salary required to be considered one of the highest earners in Texas amounts to $762,090 in 2024.

Texas has the 14th highest pre-tax salary needed to be considered in the top one percent of earners in the U.S. for the second year in a row. Texas' income threshold is not too far off from the national average, which is $787,712.

The study further revealed 126,128 Texans are within the top one percent of earners. For more context, the U.S. Census Bureau says over 30 million people lived in Texas as of 2022, and Houston's population grew to 2.3 million people in 2023.

Connecticut continues to lead the nation with the highest income threshold required to be in the top one percent, with residents needing to make over $1.15 million pre-tax.

To determine the income needed to be in the top one percent of earners in each state, SmartAsset analyzed 2021 IRS data for individual tax filers, which is the most recent year where data was available. Income data was then adjusted to June 2024 dollars.

Compared to SmartAsset's 2023 report, Texans now need to make $130,241 more in 2024 to maintain their status as one of the highest earners in the state. Last year, the income threshold was $631,849.

If Houstonians aim to be within the top five percent of earners in Texas, the pre-tax income threshold is drastically lower, at $280,676. However, for many Houston residents, achieving even a "middle class" status means making between $40,280 and $120,852 a year.

Meanwhile, the study says the median income in the U.S. comes out to roughly $75,000, and half of Americans are making even less than that. The income disparity is plainly obvious when high-income earners make (at a minimum) 10 times more than the national median income.

The report goes on to say top-earning Americans make up a "disproportionately large part of the tax base," as their income results in paying a 37 percent federal tax bracket rate. (That is, if these high earners are even paying taxes in the first place, considering America's wealthiest are already evading over $150 billion a year in taxes.)

"While state and local level taxes may impact the spread of high earners in those areas, the cost of living can also be drastically different nationwide," the report said. "As a result, what it takes to be considered a top one percent income earner can differ by over $500,000 from state to state."

The top 10 states with the highest thresholds to be considered in the top one percent of earners in the U.S. are:

  • No. 1 – Connecticut ($1,152,254)
  • No. 2 – Massachusetts ($1,113,662)
  • No. 3 – California ($1,035,673)
  • No. 4 – Washington ($989,649)
  • No. 5 – New Jersey ($975,645)
  • No. 6 – New York ($965,645)
  • No. 7 – Colorado ($865,700)
  • No. 8 – Florida ($852,206)
  • No. 9 – Wyoming ($843,121)
  • No. 10 – New Hampshire ($811,098)
The full report can be found on smartasset.com

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This article originally ran on CultureMap.