3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Alessio Lorusso of Roboze, Tobi Smith of All I Do Is Cook, and Pradeep Sharma of the University of Houston. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from 3D printing to food and cooking — recently making headlines in Houston innovation.

Alessio Lorusso, founder and CEO of Roboze

Alessio Lorusso joins the Houston Innovators Podcast to discuss why he chose Houston to set up U.S. operations for his large-scale 3D printing company, and how the city has the potential to become a hub for the industry. Photo via LinkedIn

The hit the pandemic has had on the global supply chain has been a huge hit to so many companies. However, one Italian company with its United States headquarters in Houston, has an alternative for customers — large scale, in-house production. Roboze, which recently completed a multimillion-dollar fundraise, has seen explosive growth due in large part to how COVID-19 has affected the global supply chain over this past two years.

"This was an incredible accelerator for us," says Alessio Lorusso, CEO and founder, on the Houston Innovators Podcast. He adds that, while Roboze has attracted large corporate customers, the business is seeing growth in the small to mid-sized company sector.

"The moment is now," Lorusso says. "The time to integrate printing capabilities and have the possibility to print parts in house is something that needs to be done now." Click here to read more and listen to the podcast.

Tobi Smith, founder of All I Do Is Cook

All I Do Is Cook is on a mission to grow accessibility to Nigerian dishes. Image via allidoiscook.com

Tobi Smith wanted to take his business to the next level — and he found the perfect opportunity to do so. After completing the gBETA accelerator program and winning the grand prize in the ClearCo ClearPitch competition, Smith and his business partner Bethany Oyefeso are transitioning their small business, All I Do Is Cook, into a startup with the ultimate goal of making Nigerian food accessible to everybody.

Smith and Oyefeso came one step closer to that goal when Phoencia, a Houston grocery story, started stocking the startup's condiments in 2021. In that same year, Smith and Oyefesso joined the gBETA accelerator program. Smith described this program as being instrumental in the advancement of their company from a small business to a start up, now at the beginning of their pre-seed funding phase.

“They taught us everything about what it meant to be a start up and connected us with mentors and other individuals working in the food and beverage space,” says Smith. Click here to read more.

Pradeep Sharma, engineering department chair at the University of Houston

Pradeep Sharma, M.D. Anderson Chair Professor and department chair at the University of Houston, was named to the National Academy of Engineering. Photo via uh.edu

The National Academy of Engineering elected its new members, and five local scientists are among the new 133-person cohort — as is Elon Musk, if you were wondering. The appointment is among the highest professional distinctions in an engineer's career.

Pradeep Sharma, M.D. Anderson Chair Professor and department chair, Department of Mechanical Engineering, University of Houston, was recognized for establishing the field of flexoelectricity, leading to the creation of novel materials and devices and insights in biophysical phenomena.

“Nature has provided us very few piezoelectric materials even though their applications in energy harvesting and in making sensors is very important. What we did was use theory to design materials that perform like piezoelectric ones, so that they can create electricity,” says Sharma in the release. Click here to read more.

Why this innovator wants to make Houston a hub for 3D printing

Houston innovators podcast episode 121

When Alessio Lorusso founded his company in 2014, he saw a huge gap in the 3D printing market — and he wanted to be the person to fill it.

Lorusso, CEO and founder of Roboze, shares on the Houston Innovators Podcast, that historically 3D printing has been used for prototypes and testing, before companies decide to turn to larger scale manufacturing — typically done overseas.

"I thought at that time — and still today — that 3D printing needed to demonstrate that it was a real capable technology to produce and use parts instead of prototypes," Lorusso says. "This was my goal — and still is my goal — to bring this technology to the production shop floor."

Now, Roboze works with companies to put their large-scale 3D printer on site to support in-house part and tool creation. Roboze's technology, the ARGO 1000 has the ability to produce parts up to one cubic meter — about 40 inches by 40 inches by 40 inches. This size of output allows for on-demand manufacturing at scale. Additionally, the device uses more sustainable and high-performing super polymers and composites such as PEEK, Carbon PEEK and ULTEM ™ AM9085F.

"We are helping our customers to digitize their inventory," Lorusso says on the podcast, "but this is much more than 3D printing. This is supply chain reshaping. This is a production reshoring."

Roboze, which recently completed a multimillion-dollar fundraise, has seen explosive growth due in large part to how COVID-19 has affected the global supply chain over this past two years.

"This was an incredible accelerator for us," he says, adding that, while Roboze has attracted large corporate customers, the business is seeing growth in the small to mid-sized company sector.

"The moment is now," Lorusso says. "The time to integrate printing capabilities and have the possibility to print parts in house is something that needs to be done now."

Roboze set up its United States headquarters in Houston in the summer of 2020, and has hit the ground running in terms of connecting to the ecosystem. Lorusso observes that some of the city's key industries — health care, aerospace, energy, and transportation — are all ripe for disruption by 3D printing — and by Roboze specifically.

"We are super committed in making Houston one of the most important cities in the U.S. for 3D printing. What we are trying to create is an ecosystem in the city," he says. "There is an incredible potential."

Lorusso shares more on where he sees the future of 3D printing heading and why he's committed to Houston on the podcast. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

Roboze has closed its latest round of funding. Photo courtesy of Roboze

Houston 3D printing company closes latest round of funding, plans to hire

money moves

Roboze — an Italian high-performance 3D printing company with its U.S. headquarters in Houston — closed a multimillion-dollar round of funding this month with investments from an international group of leaders from diverse backgrounds.

Investors include Nova Capital, Lagfin, Andrea Guerra, Luigi De Vecchi, Roberto Ferraresi, Luca Giacometti, Denis Faccioli and others, according to a statement.

“We are honored to have a group of investors of this caliber, who strongly believe in the vision of Roboze and in the change of production paradigm that our technology is enabling by replacing metals and producing parts without wasting raw materials," Alessio Lorusso, founder and CEO of Roboze, said in a statement.

Roboze aims to put the funds towards the research and development of a new "super material" developed in the company's R&D facility in Italy, where the company is also building a new chemistry lab.

The company added that it will also be implementing an aggressive hiring plan in 2022, hiring 60 experts in the next 12 to 18 months in fields such as materials science, chemistry, business development, aerospace, medical devices, and field and applications engineering. Half of the new jobs will be based in the U.S. while the others are slated to be located in Italy and Germany.

Roboze specializes in manufacturing industrial 3D printing technology, such as its ARGO1000, which the company says is the largest printer of its kind. Through a process called Metal Replacement 3D Printing, the company uses super polymers and composites like PEEK and Carbon PEEK to create large-scale, end-use parts for an array of industries—from aeronautics equipment to medical manufacturing.

The company currently works with GE, Bosch, and Airbus, among others, and announced in the statement that manufacturing giant Siemens Energy acquired its first 3D printer from the company.

"We think additive manufacturing is playing a key role in digitalization and cost out in the energy sector. At Siemens Energy we evaluated many companies and found that Roboze technology for high temperature polymers has met our engineering qualification and expectations," Andrew Bridges, Service Frame Owner at Siemens Energy, said in a statement. "As a result, we acquired our first machine and look forward to expanding our relationship with Roboze."

Roboze's latest technology is the biggest on the market. Image courtesy of Roboze

Tech company unveils the 'world's largest 3D printer' in Houston

Texas sized

An Italian company that specializes in manufacturing industrial 3D printing technology has released the largest 3D printer on the market. And the company, which has its North American headquarters in Houston, chose the Bayou City to go live with the innovative product.

Roboze revealed the ARGO 1000 — a 3D printer that Roboze is calling the biggest in the world — which will be available for commercial distribution in 2022. The device has a heated chamber designed to produce large-scale parts with super polymers and composites for industrial applications, according to a news release.

"After years of specializing in super polymers and high-temperature composites and paving the future of industrial 3D printing, we are excited to introduce our flagship Production Series solution, ARGO 1000," says Alessio Lorusso, founder and CEO of Roboze, in the release. "Since we announced the opening of our new headquarters in North America earlier this year, we have grown our global customer base and invested in R&D to fulfill customer demand for a much larger 3D heated chamber super polymer printer."

Roboze announced its U.S. HQ just over a year ago. The company told InnovationMap that the new office was intended to grow Roboze's presence in oil and gas. The new industrial-sized printer too will impact the company's presence in the energy industry, as well as aerospace, transportation, medical, and automotive.

The ARGO 1000 has the ability to produce parts up to one cubic meter — about 40 inches by 40 inches by 40 inches. This size of output allows for on-demand manufacturing at scale. Additionally, the device uses more sustainable and high-performing super polymers and composites such as PEEK, Carbon PEEK and ULTEM ™ AM9085F, per the release.

The company's technology, including its industrial automation system and proprietary gear-based (beltless) technology, also allows for the production of parts that are six times more precise than those made with belt-driven printers, reports the release.

"We have gone far beyond prototypes and are now building custom components for miniature satellites, gears for military-grade vessels, and parts for companies developing the nation's sustainable infrastructure," says Lorusso in the release. "Our technologies ensure precise process control is maintained through the automation of every setting and calibration phase, resulting in continuous accuracy, repeatability, and the certification of every single part produced."

Last year, Roboze announced its American headquarters in Houston. Now the company is announcing something big. Photo courtesy of Roboze

Growing Italian company with U.S. HQ in Houston launches new industrial-scale 3D printing

bigger in texas

An Italian-American manufacturer of 3D parts and printers with its U.S. headquarters in Houston is touting what's billed as a first-of-its-kind innovation — an innovation that's helping drive the need for more local workers.

Roboze recently introduced Roboze Automate, and it's being promoted as the world's first industrial automation system to bring customized 3D printing with super polymers and composites into the production workflow.

"As the need for strong, resilient infrastructure in the U.S. and around the world continues to climb, we are bringing 3D manufacturing to a new level of consistency, repeatability, and process control and production speed," Alessio Lorusso, founder and CEO of Roboze, says in an April 12 news release. "Our components-as-a-service approach is upending error-ridden manufacturing fluctuations and materials shortages to support true industrial-scale 3D manufacturing."

Roboze cranks out 3D-printed parts for customers in industries like aerospace and aviation, energy, oil and gas, transportation, defense, and research. It also sells 3D printers to industrial users. Among its customers are aerospace giant Airbus, appliance manufacturer Bosch, industrial conglomerate GE, defense contractor Leonardo, Pennsylvania State University, consumer electronics titan Sony, the U.S. Army, and the University of Colorado.

Last year, Roboze announced it was establishing its U.S. headquarters in Houston to support its U.S. rollout. The company employs 10 people in the U.S. The local operation, at 7934 Breen Dr. in Northwest Houston, features more than 20 industrial-scale 3D printers.

In February, Roboze said it plans to add 100 employees in the U.S. within the next two years; 30 of those new hires are expected to join the company this spring. The new employees will work in areas such as engineering, sales, and marketing. As of April 13, the Roboze website listed a dozen job openings in Houston and nine in Italy. Around the world, Roboze employs nearly 100 people.

"Houston ranks as one of the top U.S. cities for manufacturing plants and industrial employment, and [is] home to exciting scientific initiatives at the Houston Spaceport and Rice University," Lorusso, who now lives in Houston, said in February.

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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

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