When examining how you can better prepare and respond to ongoing climate-related challenges, the CRE community needs to prioritize marginalized communities that are already experiencing most of the negative impacts. Photography by Peter Molick

Houston is no stranger to hurricanes, and in recent years winter storms have become an increasing concern. Following the winter freeze in 2021, more than 4 million Texans were left without power, water, or heat. The state’s infrastructure system was adversely impacted concurrently — including workplaces, hospitals, transportation, homes, drinking water distribution, electric power generation, agriculture, and grocery stores. Now, a new potential disaster is on the horizon. Recent research shows Houston is most likely to be affected by wildfires, a climate-related challenge that our city has not previously faced.

According to the Gensler Research Institute’s 2022 U.S. Climate Action Survey, since 2019, only 18 percent of Americans believe their communities are built to withstand climate change. The good news is Americans overwhelmingly agree that addressing climate change is urgent. The question many are asking is — “How can we take action to better prepare buildings and cities to weather the climate challenge?” The solution is simple. In order to understand where we need to go, we must understand how we got here.

With a population that has more than doubled in the past 50 years, it is challenging for most Houstonians to imagine a time when The Bayou City was nothing more than agricultural lands and oil fields. Today, Houston is known for being the fourth-most populous city in the United States. It is a sprawling concrete jungle home to the world’s largest concentration of healthcare and research institutions. When reflecting on the past 50 years, one can’t help but evaluate the city’s successes and shortcomings. While Houston has succeeded in becoming a diverse, international city, we have sacrificed the very ecology that once made up one of the country’s most productive agricultural areas. By 1980, Houston possessed the least amount of green space per person in the country.

As new developments popped up across the city, it became difficult to convince developers to pursue third-party certifications such as LEED, a globally recognized symbol of sustainability that provides the framework for designing healthy, efficient, carbon saving buildings. We can credit Hines with being one of the few developers in Houston to prioritize green design during the early-2000s. City leaders also began advocating for resilient strategies and more green space to attract and retain international talent and businesses. In recent years, we have seen an increase in buildings that are achieving LEED certification, and soon it will become the baseline.

The Houston Advanced Research Center, Photography by Shau Lin Hon, Slyworks Photography

An example of a project leading the way for resilient design is The Houston Advanced Research Center (HARC). In 2017 the organization completed work on its LEED Platinum Certified headquarters which was designed to meet the ENERGY STAR certification rate of 99 (out of 100). This means that the building is more efficient than 99 percent of all office buildings in the United States. Skanska is another construction and development company bringing a sustainable mindset to downtown Houston with its work on Bank of America Tower. In 2019, the 775,000 square foot building became the largest LEED v4 Platinum Core and Shell certified project in the world to date and was developed with harvesting technology that will significantly reduce energy usage.

It’s also important to understand the impact that the climate crisis is having on people. 91 percent of U.S. Gen Z/Millennials have been affected by extreme weather events since 2019, the most of any generation. These experiences have resulted in two generations preparing to react and combat climate change and has encouraged a spirit of transparency among companies who choose to share their environmental goals and strategies.

For architects and designers, addressing building and energy codes is proving to be the next big design consideration. As codes progress in the coming years, the result will be more unique and unexpected building designs.

When reimagining the use of buildings, Architects Paulina Abella and Tayler Trojcak propose an experimental process for repurposing vacant buildings called High Hackers. The concept provides an opportunity for developers to offer prime downtown real estate to people with diverse skill sets, whom they call “hackers,” to pursue projects shaped by their individual ideas. These hackers—makers, artists, and academics—will work alongside one another in spaces that encourage them to coexist with creatives from other fields and disciplines. More importantly, it fosters a collaborative, organic, and innovative workflow.

When examining how you can better prepare and respond to ongoing climate-related challenges, we encourage prioritizing marginalized communities that are already experiencing most of the negative impacts. Promoting awareness and optimism in our communities is another simple yet effective way to make a difference. For businesses, creating a sense of continuity in the face of climate events, investing in energy and resource efficiency and adaptation, and addressing insurability and the long-term value of real estate will ultimately help lead Houston and its community members toward a place of preparedness and resiliency.

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Rives Taylor directs Gensler’s Global Design Resilience teams and initiatives and has been a faculty member of both Rice University and the University of Houston for 30 years. Maria Perez is a design resilience leader for Gensler’s South Central region and director of sustainable design based in Gensler’s Houston office. 

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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.