Mobile ordering rolls out at resort, Houston VC's latest investment, and more local innovation news

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Here's your latest roundup of Houston startup and innovation news you may have missed. Photo via Getty Images

We're on the other side of the hill that is Houston's summer, but the Bayou City's still hot — especially in terms of innovation news, and there might be some headlines you may have missed.

In this roundup of short stories within Houston startups and tech, a Houston venture capital fund has made its latest investment, Houston startups share big updates, and more.

Rivalry Technology rolls out mobile ordering at hot summer spot

You can now order poolside at this Houston-area resort. Image courtesy of Rivalry Tech

Lounging at Margaritaville Lake Resort at Lake Conroe was just made easier by Rivalry Tech, a Houston-based mobile ordering platform company. Rivalry Tech upgraded poolside ordering with its myEATz. According to a news release, customers can now order food and drinks from the 5 o’Clock Somewhere Bar and Lone Palm Bar via a custom QR code system for each lounge chair and table to increase operational efficiency for the Margaritaville Lake Resort staff.

“We wanted to be sure the rollout of the myEATz mobile ordering platform was helpful to the Margaritaville staff, not a hindrance to their existing process. We created custom QR codes and a color coded map to easily identify where the mobile orders are going,” says Charles Willis, COO of Rivalry Tech, in the release.

Rivalry, which provides mobile ordering at numerous sports stadiums and venues with sEATz, expanded into hospitality this year.

“The Rivalry Tech team helped us to seamlessly implement mobile ordering at Margaritaville Lake Resort. They created the marketing materials, established custom QR codes, uploaded mentors and trained our staff onsite. The whole process has been easy and collaborative,” says Amit Sen, director food and beverage for Margaritaville Lake Resort, in the release.

Mercury Fund invests in ReturnLogic's latest round

Mercury has led the latest fundraising round from a SaaS company. Image via Getty Images

Houston-based venture capital firm Mercury led Phillidelphia-based SaaS company ReturnLogic's $8.5 million series A funding round, which also had participation from Revolution’s Rise of the Rest Fund, White Rose Ventures, and Ben Franklin Technology Partners. The fresh funding will help the company double its workforce, accelerate product development, and expand Application Programming Interface capabilities, according to a news release.

Founded by CEO Peter Sobotta, Return Logic's SaaS platform, which can be plugged into existing e-commerce platforms, helps to enhance management of returns and prevent the challenging financial impacts of returns.

“While retailers have largely mastered forward logistics to get products into customers hands, the returns process remains an under-addressed, resource-draining problem that eats away at brands’ profits,” says Blair Garrou, managing director of Mercury, in a news release. “ReturnLogic is something entirely new to this market and uniquely built on Peter Sobotta’s deep operational experience in reverse logistics and supply chain management.

"While serving in the U.S. Navy, Peter specialized in reverse logistics and gained extensive expertise in ecommerce operations," Garrou continues. "With Peter at the helm, ReturnLogic’s innovative API-first returns solution is well-positioned to tackle the ever-growing operational returns problem facing retailers. We are excited to partner with Peter and his team as they continue to solve this massive problem for online retailers.”

Fluence Analytics named a top advanced manufacturing startup

Fluence Analytics was selected as one of 50 startups recognized. Graphic courtesy

Fluence Analytics, an analytics and process control solutions platform for the polymer and biopharmaceutical industries, was named as a Top 50 global advanced manufacturing startup by CB Insights. The Inaugural list breaks down 16 different cohorts, narrowed down from more than 6,000 companies who either submitted an application or were nominated. Fluence Analytics was one of three companies featured in the R&D Optimization category.

"Our team is very excited that our real-time process analytics, optimization and control products for the polymer and biopharma industries are included among such elite startups," says Jay Manouchehri, CEO of Fluence Analytics, in a statement to InnovationMap. "We wish to thank CB Insights for including Fluence Analytics in its inaugural list of the Top 50 global advanced manufacturing startups, as well as our customers and investors for supporting the development and roll-out of our transformative technology solutions."

Fluence Analytics moved to the Houston area from New Orleans last year. The company's tech platform allows for optimization and control products to polymer and biopharmaceutical customers worldwide.

HTX Labs secures $1.7M contract to expand within United States Air Force

HTX Labs' EMPACT product will be further developed to support the Air Force. Image courtesy of HTX Labs

HTX Labs, a Houston-based company that designs extended reality training for military and business purposes, that it has been awarded a $1.7 million Small Business Innovation Research Phase II Tactical Funding Increase with the US Air Force to enhance and operationalize to its product, EMPACT Immersive Learning Platform, in support of training modernization.

“We are very thankful to AFWERX and AFDT for this great opportunity to play an increasingly important role in helping the USAF accelerate training modernization," says Chris Verret, president HTX Labs, in a news release. "This TACFI award shows continued confidence in HTX Labs, with a strong commitment to accelerate usage and adoption of EMPACT.”

HTX Labs will leverage this contract to expand EMPACT's ability to rapidly create and distribute interactive, immersive training, collaborating closely with Advanced Force Development Technologies, per the release.

OpenStax to publish free edition of updated science textbook

OpenStax is growing its access to free online textbooks. Image via openstax.org

OpenStax, a tech initiative from Rice University that uploads free learning resources, has announced it will publish the 10th edition of an organic chemistry textbook by Cornell University professor emeritus John McMurry.

“This is a watershed moment for OpenStax and the open educational resources (OER) movement,” says Richard Baraniuk, founder and director of OpenStax, in a news release. “This publication will quickly provide a free, openly licensed, high-quality resource to hundreds of thousands of students in the U.S. taking organic chemistry, removing what can be a considerable cost and access barrier.”

Usually a big expense for organic chemistry students, McMurry, with the support of publisher Cengage, made the decision to offer the latest edition online as a tribute to his son, Peter McMurry, who died in 2019 after a long struggle with cystic fibrosis.

“If Peter were still alive, I have no doubt that he would want me to work on this 10th edition with a publisher that made the book free to students,” McMurry says in the release. “To make this possible, I am not receiving any payment for this book, and generous supporters have covered not only the production costs but have also made a donation of $500,000 to the Cystic Fibrosis Foundation to help find a cure for this terrible disease.”

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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