This week's roundup of Houston innovators includes Paul Cherukuri of Rice University, Berkley Luck of Milkify, and Reid Wiseman of NASA. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space to molecular biology — recently making headlines in Houston innovation.


Paul Cherukuri, vice president of innovation at Rice University

This Houston innovator is set on bringing more innovation off campus and into the world

Paul Cherukuri, vice president of innovation at Rice University, joins the Houston Innovators Podcast. Photo via Rice.edu

Rice University was founded on a mission of an "unfettered pursuit of knowledge," says Paul Cherukuri, the inaugural vice president for innovation at Rice University. And that goal is specifically designed to be "for the greater good of society," — especially in Houston.

"Rice is right in the middle of one of the greatest cities in the world," Cherukuri says on this week's episode of the Houston Innovators Podcast. "Houston is special on so many levels that it's ridiculous that no one outside of Houston seems to get that. ... We have a moral responsibility as Rice to do more for this city and the country."

Among the top action items on this overarching mission Rice is on is ensuring that the Rice University's inventions and research that have the potential to make the world a better place are able to commercialize to deliver on that impact. Read more.

Berkley Luck, founder and COO of Milkify

Houston-based Milkify pitched their freeze-drying breast milk concept on Shark Tank. Photo via LinkedIn

Houston startup Milkify pitched on ABC’s “Shark Tank” on Friday, April 7. Pedro Silva, co-founder and CEO, created Milkify along with his wife, Berkley Luck, PhD, in 2019. Today, Luck is a mom, COO, and a molecular biologist, but she had the idea for the company back in grad school. A coworker was struggling with pumping breast milk “lugging the pump back to work,” as Luck puts it.

Luck was studying probiotics at the time and was using a freeze-dryer in her work. The problem inspired her to create a process of freeze-drying breast milk that is now patent pending. The trademarked process is centered around SafeDry, special freeze-drying pouches.

“The breast milk never makes contact with our equipment,” Luck explains. The powdered milk is transferred directly from the bag in which it’s freeze-dried to the final packaging under sterile conditions. The result is not only shelf-stable, but keeps for at least three years, exponentially longer than frozen milk. Read more.

Reid Wiseman, NASA's Artemis II commander

Meet Commander Reid Wiseman, the responsible for the success of the Artemis II mission once it launches. Photo courtesy of NASA

Last week, NASA announced its four-person crew for Artemis II, the first manned mission to the moon in over 50 years.

While the announcement in itself — with the first person of color and first woman to head to the moon — is history making, Commander Reid Wiseman says there's still a lot of work to be done.

"When you look at our crew, our next step is to learn about the spacecraft that will be operating in deep space. It's a very capable, very redundant, robust machine. So we have to get in the classroom, we've got to learn about all the capabilities, but we also have to get out and see the workforce," Reid says. Read more.

Meet Commander Reid Wiseman, the responsible for the success of the Artemis II mission once it launches. Photo courtesy of NASA

Meet the Houstonian commanding NASA's historic return to the moon

Q&A

The world now knows the names of the four Houston-based astronauts who will launch in the first crewed moon mission in 50 years. NASA's Artemis II will see the first woman and person of color helming a lunar voyage, a first since the agency's history.

Astronaut Christina Hammock Koch, herself part of a history-making astronaut class and first all-female spacewalk— will join Victor Glover — the first person of color heading to the moon. Rookie Canadian astronaut Jeremy Hansen rounds out the crew with Commander Reid Wiseman.

Building on the unmanned Artemis I mission to the moon that concluded in December, Artemis II is slated to launch around November 2024, per NASA. In a scene familiar to space fans, the Artemis II crew will deploy inside the cozy Orion spacecraft that will sit atop the Space Launch System (SLS) rocket from Kennedy Space Center in Florida.

Artemis II's crew will spend some 10 days in orbit and even venture farther than the 1.4 million miles logged by Artemis I, adding to the historic nature of the journey. After moon orbit, the spacecraft will return to Earth for splashdown and recovery — always a celebrated moment after the highly anticipated takeoff.

Data gathered from Artemis II will pad information from Artemis I in effort to create a permanent moon outpost. On the moon, crews will learn how to live and work away from Earth, which will pave the way for the eventual mission to Mars. A planned Artemis III mission may launch in 2025 or '26, per NASA, which picks up from the last trip, Apollo 17 in 1972. The Artemis III mission, NASA promises, will see the first woman and person of color on the moon.

CultureMap caught up with a very busy Wiseman, who is now responsible for the success of the Artemis II mission once it launches. Hailing from Baltimore, Maryland, the 47-year-old earned his master's degree from Johns Hopkins University and is a decorated naval aviator, serving in the Middle East as a fighter pilot. The Artemis II mission commander completed a 165-day trip to the International Space Station in 2014 and was most recently chief of the astronaut office, per his bio. He has two sons with wife Carol, who passed away from cancer in May 2020.

The Artemis II crew was announced earlier this week. Photo courtesy of NASA

CultureMap: Congratulations, Commander. As Artemis II's leader, you are joining lunar mission commander names like the first man on the moon, Neil Armstrong, and Apollo 13's Jim Lovell. Do you allow yourself to think like that?

Reid Wiseman: Thank you. I do not allow myself to think like that. I think if you get to meet this crew — Victor Glover, Christina Koch, Jeremy Hanson — I really think we would say we want this to be so routine. We want Artemis II to be so successful and so long term that people completely forget about us. We're just that initial little stepping stone. I really hope that's the case. I am flying with an incredible group of heroes and I can't wait to go get this job done.

CM: What does it mean, as mission commander, to have the safety — and the lives — of these amazing and history-making astronauts in your hands once you launch?

RW: It means everything to me.

CM: You and the crew are so incredibly accomplished in your own individual spaces. Yet when you get to NASA — as Christina Koch once told me — you're kind of learning anew. What are you learning now?

RW: When you look at our crew, our next step is to learn about the spacecraft that will be operating in deep space. It's a very capable, very redundant, robust machine. So we have to get in the classroom, we've got to learn about all the capabilities, but we also have to get out and see the workforce.

We'll be the first humans to ever ride on this vehicle. And there's a lot of unknowns. We have a lot of systems to test. Uh One was very successful.

We need to hit the books and then we need to get in the sim [simulator], we need to practice simulations, learn how we all operate together as a team and then learn about the failure modes of the vehicle, how we can work around to keep ourselves safe and keep the mission going. And then after that, I think we'll be ready to look at Florida — and head out to the moon.

CM: Do prior lunar flight commanders and icons — like Armstrong and Lovell — serve as role models? How about the astronaut network in general?

RW: I think we look at those legends as their heroes, but they are also friends. Those folks really gave their lives to our nation and when they landed on the moon for the first time. But the amazing part for us as younger astronauts is they're still heavily engaged in everything we do right now.

I talked to Jack [Harrrison] Schmitt just a few months ago. Dave Scott still comes by every time he can to talk about geologic processes on the moon. Like these guys are our friends. It's really, really neat.

Neil Armstrong was amazing. John Young was incredible — he led our office for a number of years. Those guys are heroes to us for sure. When you look at who has taught me the most about being an astronaut, it's the folks I flew with on my first mission. It's the folks that I've worked with in the astronaut office. Now, I've seen some exceptional examples of leadership and followership and both skills are critical to be an astronaut.

CM: You learned you'll be headed to the moon — the dream adventure of billions all over the world— in the most office kind of way, we hear.

RW: Uh yeah, we all goofed up [laughs]. We missed the meeting. The chief astronaut put a placeholder on my schedule for a different topic. I was actually at a doctor's office and the doctor just walked in. So, I missed the first part of the meeting and I was able to use Microsoft Teams and dial in towards the end.

When the camera popped up, I saw the chief astronaut — who I expected to see for my meeting. But then, I also saw Norm Knight, our director of flight operations. I also saw Victor Glover and Christina Koch. And I was like, ‘oh boy, I think I just missed something big here.’

CM: Well, we've all missed meetings. But this was big — like headed to the moon big.

RW: Right [laughs]. It turned out that both Christina and Victor also missed the beginning of the meeting. So, we all showed up in perfect harmony.

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This article originally ran on CultureMap.

The history-making team was announced at Ellington Field near Johnson Space Center in Houston. Photo via LinkedIn

NASA names four astronauts heading to the moon at Houston event

ready for liftoff

NASA and the Canadian Space Agency announced the four astronauts who will be onboard the Artemis II mission around the moon yesterday at an event at Ellington Field near NASA’s Johnson Space Center in Houston.

The 10-day mission is slated to put the first woman and the first person of color on the moon.

“For the first time in more than 50 years, these individuals – the Artemis II crew – will be the first humans to fly to the vicinity of the Moon. Among the crew are the first woman, first person of color, and first Canadian on a lunar mission, and all four astronauts will represent the best of humanity as they explore for the benefit of all,” says JSC Director Vanessa Wyche. “This mission paves the way for the expansion of human deep space exploration and presents new opportunities for scientific discoveries, commercial, industry and academic partnerships and the Artemis Generation.”

The crew assignments include:

  • Commander Reid Wiseman, who has logged more than 165 days in space in two trips. He previously served as a flight engineer aboard the International Station and most recently served as chief of the Astronaut Office from December 2020 until November 2022.
  • Pilot Victor Glover, who served as pilot on NASA’s SpaceX Crew-1 mission in 2021. This will be his second trip to space.
  • Mission Specialist 1 Christina Hammock Koch, who set the record for longest single spaceflight by a woman with a total of 328 days in space and participated in the first all-female spacewalks. This will be her second flight into space.
  • Mission Specialist 2 Jeremy Hansen, representing Canada. Hansen is a colonel in the Canadian Armed Forces and former fighter pilot and has served as Capcom in NASA's Mission Control Center at Johnson Space Center. He was the first Canadian to lead a NASA astronaut class. This will be his first flight into space.

Meet the four astronauts who will return humans to the moon. Photo courtesy of NASA

“NASA astronauts Reid Wiseman, Victor Glover, and Christina Hammock Koch, and CSA astronaut Jeremy Hansen, each has their own story, but, together, they represent our creed: E pluribus unum – out of many, one," NASA Administrator Bill Nelson said. "Together, we are ushering in a new era of exploration for a new generation of star sailors and dreamers–the Artemis Generation.”

Artemis II is slated to build upon the uncrewed Artemis I mission that was completed in December. The crew will be NASA's first to aboard the agency's deep space rocket, the Space Launch System, and Orion spacecraft. They will test the spacecrafts' systems to ensure they operate as planned for humans in deep space before setting course for the moon.

NASA's Artemis program collaborates with commercial and international partners with the goal of establishing a long-term presence on the moon. Lessons learned from the missions are planned to be used to send the first astronauts to Mars.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.