Nuro, which has several pilot programs on Houston roads, has raised fresh funding — plus a few other short stories of Houston innovation. Photo courtesy of Kroger

The Houston innovation ecosystem has been bursting at the seams with news from innovative tech companies and disruptive Houston startups as we fly through the final quarter of 2021.

In this roundup of short stories within Houston innovation, a California tech company with a large presence in Houston has raised hundreds of millions in investment funding, a logistics startup has been ranked among the most innovative companies, the city of Houston has named its new sustainability leader, and more.

California tech company with huge presence in Houston raises $600M

Nuro has fresh funding to deploy its tech in Houston and beyond. Photo courtesy of Nuro

California-based Nuro, which has a large presence in Houston, announced the closing of its $600 million series D round led by Tiger Global Management with participation from Baillie Gifford, Fidelity Management & Research Company, LLC, Gaorong Capital, Google, Kroger, SoftBank Vision Fund 1, funds and accounts advised by T. Rowe Price Associates, Inc., Woven Capital, and other existing investors, per a news release. The new funding will support the development and deployment of Nuro's autonomous delivery service in communities across the country.

"We're thrilled to have the backing of these prominent investors and world class companies, and honored that they support our vision of improving communities and revitalizing local commerce," says Dave Ferguson, Nuro co-founder and president, in the release. "We believe this investment will allow us to accelerate our commercialization strategy and better everyday life with Nuro's technology."

Nuro has launched a few delivery pilots in Houston over the past few years, including the first Nuro pilot program with Kroger in March 2019, grocery delivery from Walmart that was revealed in December 2019, pharmacy delivery that launched in 2020, and pizza delivery with Domino's that went live in Woodland Heights earlier this year. Most recently, Nuro partnered with FedEx for last-mile delivery.

"Kroger launched its partnership with Nuro in 2018 to explore grocery delivery through autonomous vehicles," said Yael Cosset, senior vice president and chief information officer for Kroger, in the release. "Since then, Kroger and Nuro completed thousands of deliveries to our customers -- driving innovation that supports our expanding seamless ecosystem by creating consistent and rewarding customer experiences with scalable, sustainable, and profitable solutions."

Nuro has also signed a five year strategic partnership with Google Cloud that support the tech needed to run self-driving simulation workloads, machine learning to improve model accuracy, and storage to manage important data from the vehicles, according to the release.

Houston-based digital supply chain company launches ESG tool

Houston industrial e-commerce startup expands into the construction industry

Houston-based GoExpedi has created a new tool. Photo by Colt Melrose for GoExpedi

GoExpedi, an innovative end-to-end digital supply chain and data analytics solutions company, the launch of ESG Command. The new tool is designed to drive environmental, social and governance (ESG) initiatives. Users on GoExpedi's platform can identify environmentally-friendly products and certified veteran, minority and women-owned businesses.

"Led by some of the world's largest industrial companies, our clients are driving for more sustainable business practices and more equitable workplaces," says Yang Tang, CTO at GoExpedi, in a news release. "In support of these lofty goals and a more prosperous and environmentally-friendly global community, we grew GoExpedi's digital ecosystem to benefit our clients and suppliers. Our goal is to use technical advances in the supply chain to build a brighter future for all."

Last fall, GoExpedi raised $25 million in its series C in order to grow and scale operations. The company is growing its warehouse presence, most recently in Pittsburgh, Pennsylvania.

Houston logistics company ranks among the most innovative companies

Sugar Land-based CommtrexPhoto via commtrex.com

Commtrex, based in the Houston area, has been presented the FreightWaves 2022 FreightTech 100 award. The startup's platform connects professionals in the rail industry. The award also honored other innovative and disruptive companies in the freight industry, including Amazon Freight, DHL Supply Chain, FedEx, Flexport, Phillips Connect, Tesla, Uber Freight, Waymo, and Waze.

"Commtrex is honored and excited to be a part of the FreightWaves FreightTech 100," says Commtrex CEO Martin Lew in a news release. "Our mission at Commtrex is to simplify the movement of freight by rail. We are doing this by creating one centralized platform for shippers to efficiently connect with rail-served transloaders, storage providers, terminals, ports, warehouses, and many other resources that support the global supply chain ecosystem. As the largest rail platform in North America, we will continue to provide best-in-class service for all of our members."

Commtrex will also be eligible to be named to the FreightTech 25, which will be announced at the F3 Virtual Experience, November 9-11.

Houston fintech unicorn opens an office in Paris

HighRadius expands to Amsterdam

HighRadius has opened its newest European office. Photo via highradius.com

Continuing its expansion in Europe, HighRadius opened its new Paris office, which will have local staff for all customer facing operations including consulting, sales and marketing. The Houston-headquartered fintech unicorn also has offices in Germany, Amsterdam, the United Kingdom, India and the United States.

"The new Paris office is a sign of cementing our growing leadership in Europe and will bring the HighRadius Autonomous Software platform even closer to French companies," says Jon Keating, vice president and general manager of HighRadius in EMEA. "Our data-driven, AI software is helping global enterprises rethink and transform their finance and accounting processes. Our aim will be to deliver improvements in Days Sales Outstanding and working capital optimization, accelerate the financial close, and improve productivity in under six months for our new clients in France."

Over the past year, HighRadius has deployed over 300 transformation projects, across 37 out of 44 European countries.The HighRadius Autonomous Software platform has processed in excess of €475 billion in finance transactions in the European region alone, per a news release.

City of Houston names new sustainability leader

Priya Zachariah was named chief resilience and sustainability officer. Photo courtesy of the city of Houston

Mayor Sylvester Turner announced the appointment of Priya Zachariah as chief resilience and sustainability officer for the city of Houston. She will oversee the city's new Office of Resilience and Sustainability. The position is new and combines previously separate but similar roles, providing for more streamlined efforts to implement the Resilient Houston Plan and the Houston Climate Action Plan, according to a news release from the city.

"Sustainability and Resilience are intrinsically tied to each other. We created our resilience and climate plans to forge a path towards a stronger, more equitable city that not only faces and overcomes disaster scenarios, but builds forward to a better Houston tomorrow," says Mayor Turner in the release. "I am confident Priya will help us meet the goals we have established."

Zachariah was previously the senior program manager for Regional and Long-Range Planning at Houston METRO. While at METRO, Zachariah led the team that successfully delivered the METRONext 2040 transit plan for the Houston Region.

"This is a critical juncture for all of us. We now have the opportunity as a community to turn our focus from resilience and climate planning, to implementation and a realization of the benefits of those plans," says Zachariah in the release. "I am grateful for this opportunity and look forward to working with Mayor Turner and all stakeholders to move us toward a more resilient and equitable future."

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Rice University launches new venture fund for university-affiliated startups

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Rice University has launched its new One Giant Leap Ventures Fund I, which will invest in the university’s spinouts and alumni-founded startups.

The early-stage institutional venture fund will function with a hybrid structure that allows for participation from traditional equity investors and philanthropic investors. According to the university, the fund will invest up to $500,000 per Rice-affiliated company.

To be considered eligible for funds, companies must use intellectual property licensed by the university or be led or founded by alumni.

One Giant Leap will draw on support and mentorship from Rice’s pool of 60,000 alumni and aims to create educational opportunities within the investment phases, work with graduate and undergraduate venture students, explore the scaling and commercialization of their ideas, and help investigate all the facets of venture capital.

“Rice alumni bring an extraordinary depth of experience as entrepreneurs, investors and industry leaders, and One Giant Leap creates new ways to put that expertise to work for the next generation of Rice innovators,” Stephen Bayer, vice president for development and alumni relations, said in a news release. “It strengthens the connection between our alumni and the university while giving them meaningful opportunities to mentor, advise and support Rice-affiliated companies as they grow.”

The fund held its first close in August and made its first investment into Rice brain health spinout Motif Neurotech. Led by Rice faculty member Jacob Robinson, Motif is working to commercialize a minimally invasive neurostimulator that targets treatment-resistant depression. In May, the FDA approved the company to move forward with its first clinical trial.

“Research produces breakthrough technologies and our academic environment forms outstanding entrepreneurs,” said Adrian Trömel, the fund’s managing director, a Rice alumnus and a startup founder who also serves as Rice’s interim chief innovation officer.

One Giant Leap joins the already long list of Rice-led programs that foster innovation, including the Liu Idea Labs for Innovation and Entrepreneurship’s Innovation Fellows and Summer Venture Studio, the Rice Alliance’s Business Plan Competition, the Ion District, Woodside Rice Decarbonization Accelerator, Rice Nexus, the Biotech Launchpad and RBL Ventures and its upcoming 200,000 square-foot research lab the Arc.

“With One Giant Leap, I am excited that we are creating a unique structure that brings together traditional investment and philanthropic participation to invest in and help catalyze our startups, engage the deep expertise within the Rice ecosystem and transform those strengths into real-world impact,” Trömel added in the release.

New statewide plan aims to eliminate cervical cancer in Texas by 2032

fighting cancer

MD Anderson, on behalf of a coalition of health systems, has announced a new plan to eliminate cervical cancer in Texas.

The five-year Texas Lone Star Cervical Cancer Elimination Plan was launched during the Cancer Prevention and Research Institute of Texas (CPRIT) 2026 Innovations Conference in Galveston this month.

The plan focuses on three major pillars with goals to be achieved by 2032:

  • HPV vaccination: Increase the percentage of Texas boys and girls up to date on human papillomavirus (HPV) vaccination by age 15 from 50.5 percent to 80 percent
  • Cervical cancer screening: Raise the share of Texas women up to date on cervical cancer screening from 64 percent to 80 percent
  • Timely follow-up, diagnosis and treatment: Ensure 80 percent of women receive diagnostic follow-up and treatment when needed through community outreach, patient navigation, provider training and survivorship support

Overall, the coalition wants to see fewer than four new cases of cervical cancer annually per 100,000 Texas women by 2032, according to a news release from MD Anderson. Currently, Texas has an incidence rate of 9.5 women per 100,000 diagnosed with cervical cancer, compared with 7.5 women per 100,000 nationally.

“Texas has the tools to prevent nearly every case of cervical cancer, but tools can save lives only when people can utilize them,” Dr. Ernest Hawk, vice president and division head of Cancer Prevention and Population Sciences at MD Anderson, said in the release. “The Lone Star Cervical Cancer Elimination Plan gives us a shared roadmap to vaccinate more of our children, screen more of our women and make sure every abnormal result leads to care. With innovations like HPV self-collection and the commitment of partners across the state, elimination is within reach.”

About 40 other hospitals, health care organizations and companies join MD Anderson in the coalition that launched the Lonestar Plan. Those based in Houston include Houston Methodist, Rice University, UTHealth Houston, Texas Children's Hospital, Houston Health Department and others.

The CPRIT also announced its Texans Conquer Cancer Awards and its CPRIT Champion awards during the Innovations Conference this week. Several are based in Houston, including:

  • Zhiqiang An, co-founder of CrossBridge Bio, Director of the Texas Therapeutics Institute, and Vice President of Drug Discovery at the University of Texas Health Science Center at Houston
  • Dr. Abbey Berenson, Director of the UTMB Center for Interdisciplinary Research in Women's Health Care
  • Dr. Michael Taylor, Chair of Pediatric Neuro-Oncology at Texas Children's Cancer and Hematology Center and Director of Texas Children's Pediatric Brain Tumor Research Program

To date, the CPRIT has awarded more than $4.2 billion in grants to fight cancer in the state. Over the summer, it awarded four $2 million grants to institutions in Houston and Bryan for the creation or expansion of “core” cancer research facilities.

Texas Medical Center Innovation recently announced that its $2 million grant would renew its Accelerator for Cancer Therapeutics for five years. Read more from TMCi about the renewal here.

Announcing the 2026 Houston Innovation Awards finalists

Inspirational Innovators

InnovationMap is proud to reveal the finalists for the 2026 Houston Innovation Awards.

The sixth annual Houston Innovation Awards program returns in an all-digital format this fall to honor the best of Houston's innovation ecosystem, including startups, entrepreneurs, mentors, and more.

Finalists were determined by our esteemed panel of judges, comprised of past award winners and InnovationMap editorial leadership.

The panel reviewed applications across 10 prestigious categories to determine our finalists. They will select the winner for each category, except for Startup of the Year, which will be chosen by the public via online voting launching later this month.

We will announce the honoree of our annual Trailblazer Award in the coming weeks, then stay tuned as we unveil all of this year's winners on InnovationMap.com in mid-November.

Get to know our finalists in more detail through editorial spotlights leading up to the winner announcement. Without further ado, here are the 2026 Houston Innovation Awards finalists:

Minority-founded Business

Honoring an innovative startup founded or co-founded by BIPOC or LGBTQ+ representation:

  • AI Made Fun
  • Deep Anchor Solutions
  • HEXAspec
  • Prana Surgical
  • Torres Orbital Mining Inc.

Female-founded Business

Honoring an innovative startup founded or co-founded by a woman:

  • Adair
  • ARIX Technologies
  • Bairitone Health
  • FlowCellutions
  • ParaDocs Health

Energy Transition Business

Honoring an innovative startup providing a solution within renewables, climatetech, clean energy, alternative materials, circular economy and beyond:

  • Capwell Services
  • FlowCellutions
  • Hertha Metals
  • Mars Materials
  • Solidec

Health Tech Business

Honoring an innovative startup within the health and medical technology sectors:

  • Bairitone Health
  • InformAI Inc.
  • Prana Surgical
  • Skybound MedTech

Deep Tech Business

Honoring an innovative startup providing technology solutions based on substantial scientific or engineering challenges, including those in the AI, robotics and space sectors:

  • Casimir
  • Focis AI
  • Machine Saver Inc.
  • Square Robot
  • Venus Aerospace

Startup of the Year (People's Choice)

Honoring a startup celebrating a recent milestone or success. The winner will be selected by the community via an online voting experience:

  • Fluxworks
  • IronLattice
  • Lumino
  • Progress Report
  • Rosarium Health
  • Thread
  • TokenRoster

Scaleup of the Year

Honoring an innovative later-stage startup that's recently reached a significant milestone in company growth:

  • Erock
  • Hertha Metals
  • Venus Aerospace

Incubator/Accelerator of the Year

Honoring a local incubator or accelerator that is championing and fueling the growth of Houston startups:

  • Activate
  • Impact Hub Houston
  • MarMo Innovation

Mentor of the Year

Honoring an individual who dedicates their time and expertise to guide and support budding entrepreneurs:

  • Al Danto, Rice University
  • Eric Rubenstein, New Climate Ventures
  • Jeremy Pitts, Activate
  • Joe Alapat, Liongard
  • Kyle Judah, Rice University's Liu Idea Lab for Innovation & Entrepreneurship
  • Rachel Bickham, Bickham Services Unlimited LLC

Trailblazer Recipient

  • To be announced