Nuro scores $600M, Houston e-commerce startup launches ESG tool, and more local innovation news

short stories

Nuro, which has several pilot programs on Houston roads, has raised fresh funding — plus a few other short stories of Houston innovation. Photo courtesy of Kroger

The Houston innovation ecosystem has been bursting at the seams with news from innovative tech companies and disruptive Houston startups as we fly through the final quarter of 2021.

In this roundup of short stories within Houston innovation, a California tech company with a large presence in Houston has raised hundreds of millions in investment funding, a logistics startup has been ranked among the most innovative companies, the city of Houston has named its new sustainability leader, and more.

California tech company with huge presence in Houston raises $600M

Nuro has fresh funding to deploy its tech in Houston and beyond. Photo courtesy of Nuro

California-based Nuro, which has a large presence in Houston, announced the closing of its $600 million series D round led by Tiger Global Management with participation from Baillie Gifford, Fidelity Management & Research Company, LLC, Gaorong Capital, Google, Kroger, SoftBank Vision Fund 1, funds and accounts advised by T. Rowe Price Associates, Inc., Woven Capital, and other existing investors, per a news release. The new funding will support the development and deployment of Nuro's autonomous delivery service in communities across the country.

"We're thrilled to have the backing of these prominent investors and world class companies, and honored that they support our vision of improving communities and revitalizing local commerce," says Dave Ferguson, Nuro co-founder and president, in the release. "We believe this investment will allow us to accelerate our commercialization strategy and better everyday life with Nuro's technology."

Nuro has launched a few delivery pilots in Houston over the past few years, including the first Nuro pilot program with Kroger in March 2019, grocery delivery from Walmart that was revealed in December 2019, pharmacy delivery that launched in 2020, and pizza delivery with Domino's that went live in Woodland Heights earlier this year. Most recently, Nuro partnered with FedEx for last-mile delivery.

"Kroger launched its partnership with Nuro in 2018 to explore grocery delivery through autonomous vehicles," said Yael Cosset, senior vice president and chief information officer for Kroger, in the release. "Since then, Kroger and Nuro completed thousands of deliveries to our customers -- driving innovation that supports our expanding seamless ecosystem by creating consistent and rewarding customer experiences with scalable, sustainable, and profitable solutions."

Nuro has also signed a five year strategic partnership with Google Cloud that support the tech needed to run self-driving simulation workloads, machine learning to improve model accuracy, and storage to manage important data from the vehicles, according to the release.

Houston-based digital supply chain company launches ESG tool

Houston industrial e-commerce startup expands into the construction industry

Houston-based GoExpedi has created a new tool. Photo by Colt Melrose for GoExpedi

GoExpedi, an innovative end-to-end digital supply chain and data analytics solutions company, the launch of ESG Command. The new tool is designed to drive environmental, social and governance (ESG) initiatives. Users on GoExpedi's platform can identify environmentally-friendly products and certified veteran, minority and women-owned businesses.

"Led by some of the world's largest industrial companies, our clients are driving for more sustainable business practices and more equitable workplaces," says Yang Tang, CTO at GoExpedi, in a news release. "In support of these lofty goals and a more prosperous and environmentally-friendly global community, we grew GoExpedi's digital ecosystem to benefit our clients and suppliers. Our goal is to use technical advances in the supply chain to build a brighter future for all."

Last fall, GoExpedi raised $25 million in its series C in order to grow and scale operations. The company is growing its warehouse presence, most recently in Pittsburgh, Pennsylvania.

Houston logistics company ranks among the most innovative companies

Sugar Land-based CommtrexPhoto via commtrex.com

Commtrex, based in the Houston area, has been presented the FreightWaves 2022 FreightTech 100 award. The startup's platform connects professionals in the rail industry. The award also honored other innovative and disruptive companies in the freight industry, including Amazon Freight, DHL Supply Chain, FedEx, Flexport, Phillips Connect, Tesla, Uber Freight, Waymo, and Waze.

"Commtrex is honored and excited to be a part of the FreightWaves FreightTech 100," says Commtrex CEO Martin Lew in a news release. "Our mission at Commtrex is to simplify the movement of freight by rail. We are doing this by creating one centralized platform for shippers to efficiently connect with rail-served transloaders, storage providers, terminals, ports, warehouses, and many other resources that support the global supply chain ecosystem. As the largest rail platform in North America, we will continue to provide best-in-class service for all of our members."

Commtrex will also be eligible to be named to the FreightTech 25, which will be announced at the F3 Virtual Experience, November 9-11.

Houston fintech unicorn opens an office in Paris

HighRadius expands to Amsterdam

HighRadius has opened its newest European office. Photo via highradius.com

Continuing its expansion in Europe, HighRadius opened its new Paris office, which will have local staff for all customer facing operations including consulting, sales and marketing. The Houston-headquartered fintech unicorn also has offices in Germany, Amsterdam, the United Kingdom, India and the United States.

"The new Paris office is a sign of cementing our growing leadership in Europe and will bring the HighRadius Autonomous Software platform even closer to French companies," says Jon Keating, vice president and general manager of HighRadius in EMEA. "Our data-driven, AI software is helping global enterprises rethink and transform their finance and accounting processes. Our aim will be to deliver improvements in Days Sales Outstanding and working capital optimization, accelerate the financial close, and improve productivity in under six months for our new clients in France."

Over the past year, HighRadius has deployed over 300 transformation projects, across 37 out of 44 European countries.The HighRadius Autonomous Software platform has processed in excess of €475 billion in finance transactions in the European region alone, per a news release.

City of Houston names new sustainability leader

Priya Zachariah was named chief resilience and sustainability officer. Photo courtesy of the city of Houston

Mayor Sylvester Turner announced the appointment of Priya Zachariah as chief resilience and sustainability officer for the city of Houston. She will oversee the city's new Office of Resilience and Sustainability. The position is new and combines previously separate but similar roles, providing for more streamlined efforts to implement the Resilient Houston Plan and the Houston Climate Action Plan, according to a news release from the city.

"Sustainability and Resilience are intrinsically tied to each other. We created our resilience and climate plans to forge a path towards a stronger, more equitable city that not only faces and overcomes disaster scenarios, but builds forward to a better Houston tomorrow," says Mayor Turner in the release. "I am confident Priya will help us meet the goals we have established."

Zachariah was previously the senior program manager for Regional and Long-Range Planning at Houston METRO. While at METRO, Zachariah led the team that successfully delivered the METRONext 2040 transit plan for the Houston Region.

"This is a critical juncture for all of us. We now have the opportunity as a community to turn our focus from resilience and climate planning, to implementation and a realization of the benefits of those plans," says Zachariah in the release. "I am grateful for this opportunity and look forward to working with Mayor Turner and all stakeholders to move us toward a more resilient and equitable future."

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6 female-founded startups shaping the Houston innovation ecosystem

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Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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The Houston Innovation Awards program is sponsored by Houston Community College, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Former NASA astronaut, official joins Venus Aerospace board

astronaut appointment

Retired Air Force colonel and former NASA astronaut Pamela Melroy, who previously served as deputy administrator of NASA, recently joined the board of directors at Houston-based Venus Aerospace.

Venus Aerospace, a startup founded in 2020, develops rocket engine technology, including rotating rocket detonation engines for hypersonic flights. These engines promise higher power, greater fuel efficiency and lower emissions than conventional rocket engines or jet engines, according to the Interesting Engineering website. The global rocket propulsion market is expected to grow from $9.5 billion in 2025 to $29.9 billion by 2034, according to a forecast by ResearchAndMarkets.com.

“Advanced rocket propulsion has been of interest to me for over a decade, and Venus Aerospace’s recent achievements in demonstrating the stability of rotating detonation rocket engines represent a significant development,” says Melroy, who left NASA earlier this year and is now a self-employed consultant living in Arlington, Virginia.

Melroy, a member of the United States Astronaut Hall of Fame, has built an illustrious career in the aerospace sector. Aside from being a NASA official, she was:

  • One of only two female astronauts to command a space shuttle mission
  • Deputy program manager of Orion space exploration initiatives at aerospace and defense contractor Lockheed Martin
  • Senior technical adviser and director of field operations for the Federal Aviation Administration’s Office of Commercial Space Transportation, where she came up with the first safety guidelines for commercial human spaceflight
  • Deputy director of the Tactical Technology Office at the Defense Advanced Research Projects Agency (DARPA).
  • An adviser for the establishment of the Australian Space Agency

Venus Aerospace said in a news release that as a leader at three federal agencies, “Melroy shaped America’s strategy in space, accelerated commercial space partnerships, and deepened space exploration.”

Sassie Duggleby, co-founder and CEO of Venus Aerospace, called Melroy “a preeminent leader in the world of aerospace.”

In May, Venus Aerospace completed the inaugural test flight of its rotating detonation rocket engine. The startup, whose headquarters is at the Houston Spaceport, says it’s the only company in the world that has manufactured a flight-proven, high-thrust rotating detonation rocket engine.

On the horizon for Venus Aerospace is production of Stargazer M4, a high-speed aircraft capable of two-hour global travel.

Venus Aerospace’s investors include Airbus Ventures, America’s Frontier Fund, Trousdale Ventures, and Prime Movers Lab. The startup also gets support from the Air Force Research Laboratory (AFWERX), the Air Force, NASA and DARPA.

Jordan Blashek, co-founder and managing partner of America’s Frontier Fund, which backs startups creating breakthrough technologies, said his firm’s investment in Venus Aerospace “underscores our focus on supporting American companies that are revolutionizing industries of the future.”

“With recent hypersonic advancements from China and Russia, safeguarding American innovation and securing our industrial base has never been more urgent,” Blashek added. “Venus Aerospace is poised to redefine hypersonic flight and ensure America’s continued leadership in aerospace innovation.”

Since its founding, Venus Aerospace has raised $78.3 million in investments, according to PitchBook data.

Texas-based energy startup raises $1 billion on heels of Houston expansion

Powering Up

Austin-based startup Base Power, which offers battery-supported energy in the Houston area and other regions, has raised $1 billion in series C funding—making it one of the largest venture capital deals this year in the U.S.

VC firm Addition led the $1 billion round. All of Base Power’s existing major investors also participated, including Trust Ventures, Valor Equity Partners, Thrive Capital, Lightspeed Venture Partners, Andreessen Horowitz (a16z), Altimeter, StepStone Group, 137 Ventures, Terrain, Waybury Capital, and entrepreneur Elad Gil. New investors include Ribbit Capital, Google-backed CapitalG, Spark Capital, Bond, Lowercarbon Capital, Avenir Growth Capital, Glade Brook Capital Partners, Positive Sum and 1789 Capital Management.

Coupled with the new $1 billion round, Base Power has hauled in more than $1.27 billion in funding since it was founded in 2023.

Base Power supplies power to homeowners and the electric grid through a distributed storage network.

“The chance to reinvent our power system comes once in a generation,” Zach Dell, co-founder and CEO of Base Power, said in a news release. “The challenge ahead requires the best engineers and operators to solve it, and we’re scaling the team to make our abundant energy future a reality.”

Zach Dell is the son of Austin billionaire and Houston native Michael Dell, chairman and CEO of Round Rock-based Dell Technologies.

In less than two years, Base Power has developed more than 100 megawatt-hours of battery-enabled storage capacity. One megawatt-hour represents one hour of energy use at a rate of one million watts.

Base Power recently expanded its service to the city of Houston. It already was delivering energy to several other communities in the Houston area. To serve the Houston region, the startup has opened an office in Katy.

The startup also serves the Dallas-Fort Worth and Austin markets. At some point, Base Power plans to launch a nationwide expansion.

To meet current and future demand, Base Power is building its first energy storage and power electronics factory at the former downtown Austin site of the Austin American-Statesman’s printing presses.

“We’re building domestic manufacturing capacity for fixing the grid,” Justin Lopas, co-founder and chief operating officer of Base Power, added in the release. “The only way to add capacity to the grid is [by] physically deploying hardware, and we need to make that here in the U.S. ... This factory in Austin is our first, and we’re already planning for our second.”

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This article originally appeared on EnergyCapitalHTX.com.

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