This week's roundup of Houston innovators includes Sarah Hein of March Biosciences, Sean Kelly of Amperon, Donnell Debnam Jr. of the Google in Residence program, and the 2023 Houston Innovation Awards judges. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries, from biotech to energy software, recently making headlines in Houston innovation — plus the decision makers for the Houston Innovation Awards.

Sarah Hein, CEO and co-founder of March Biosciences

Early-stage cell therapy startup March Biosciences has partnered with CTMC. Photo via march.bio

Named in part after one of the best months out of the year for Houstonians, March Biosciences has entered into a uniquely Houston partnership. Sarah Hein, CEO and co-founder of the cancer immunotherapy startup, met her co-founders at the TMC Accelerator for Cancer Therapeutics.

“It's a perfect example of the opportunities here in Houston where you can go from bench to bedside, essentially, in the same institution. And Baylor has been particularly good at that because of the Center for Cell and Gene Therapy,” says Hein.

The company recently announced a partnership with another Houston institution, CTMC. Read more.

Sean Kelly, CEO and co-founder of Amperon

It's payday for a startup that's improving analytics for its energy customers. Photo via Getty Images

Amperon Holdings Inc. raised $20 million in its latest round of funding in order to accelerate its energy analytics and grid decarbonization technology.

The fresh funding will support the company in evolving its platform that conducts electricity demand forecasting to a comprehensive data analytics solution.

“The energy transition is creating unprecedented market volatility, and Amperon is uniquely positioned to help market participants better navigate the transitioning grid – both in the U.S. and as we expand globally,” Sean Kelly, CEO and co-founder of Amperon, says. Read more.

Donnell Debnam Jr., instructor in the Google in Residence program

Thanks to Google, Donnell Debnam Jr. is helping train future software engineers at Prairie View A&M University. Photo via LinkedIn

Computer science students at Prairie View A&M University are gaining firsthand knowledge this semester from a Google software engineer.

As an instructor in the Google in Residence program, Donnell Debnam Jr. is helping train future software engineers — and other potential tech professionals — who are enrolled this fall in Prairie View A&M’s introductory computer science course. Fifty-four students are taking the class.

“I participated in the Google in Residence program as a student, and I am honored to return as an instructor,” says Debnam. “This innovative program was created to support greater diversity in the tech industry, and as an instructor, I have the privilege of helping the next generation of software engineers create a more inclusive culture within the STEM fields.” Read more.

2023 Houston Innovation Awards judges

Bonus innovators to know: The 10 Houstonians deciding the finalists and winners for this year's Houston Innovation Awards. Photos courtesy

Ten Houstonians are in the hot seat for deciding the best companies and individuals in Houston's innovation ecosystem.

InnovationMap has announced its 2023 Houston Innovation Awards judging panel, which includes startup founders, nonprofit leaders, investors, corporate innovators, and more.

Meet the 10 selected judges who will evaluate applications from the nearly 400 nominations that were submitted this year. Read more.

Thanks to Google, Donnell Debnam Jr. is helping train future software engineers at Prairie View A&M. Photo via LinkedIn

Google program plants software expert at Houston-area university

meet the faculty

Computer science students at Prairie View A&M University are gaining firsthand knowledge this semester from a Google software engineer.

As an instructor in the Google in Residence program, Donnell Debnam Jr. is helping train future software engineers — and other potential tech professionals — who are enrolled this fall in Prairie View A&M’s introductory computer science course. Fifty-four students are taking the class.

“I participated in the Google in Residence program as a student, and I am honored to return as an instructor,” says Debnam. “This innovative program was created to support greater diversity in the tech industry, and as an instructor, I have the privilege of helping the next generation of software engineers create a more inclusive culture within the STEM fields.”

Prairie View A&M is one of 14 historically black colleges and universities (HBCUs) and Hispanic-serving schools that are benefiting this fall from the Google residency program. Since being founded in 2013, the program has enabled more than 8,000 college students across the country to absorb knowledge from Google tech professionals.

The Google program addresses a nationwide gap in tech diversity.

A 2023 report from CompTIA, a trade group for the tech industry, shows Black professionals make up 12 percent of the U.S. workforce but eight percent of tech occupations, while Hispanic professionals represent 17 percent of the U.S. workforce but eight percent of tech occupations.

Prairie View A&M, an HBUC, is one of two Texas universities in this fall’s program. The other is the University of Texas at El Paso, a Hispanic-serving school. The main campus of Prairie View A&M is roughly 45 miles northwest of Houston.

Google says Debnam is equipping students at Prairie View A&M “with the skills needed to enter the workforce, such as fundamental coding concepts, how to debug, and how to prepare for technical interviews.”

As a student in 2017, Debnam participated in the Google residency program at Hampton University, an HBCU in Hampton, Virginia. In a LinkedIn post, Debnam wrote that since then, “I always said to myself and others that if I could figure out a way to get into Google someday, I would make it a priority to try to be part of this program.”

After completing two Google internships and earning a bachelor’s degree in computer science from Hampton, Debnam joined the tech giant as a full-time software engineer in 2021.

“If you know me, you know I have a passion for tech, but an even deeper passion for working with students and being a resource in any way possible,” he wrote on LinkedIn.

A new program is launching to support the next generation of energy innovators. Photo via greentownlabs.com

Greentown Labs launches student-driven entrepreneurship program in Texas

back to school

The country's largest climatetech startup incubator and several schools are teaming up to prepare the next generation of clean energy innovators.

Greentown Labs, based in Boston and Houston, announced its new Texas Entrepreneurship Exchange for Energy (TEX-E) this week. The collaborative initiative aims to strengthen the student-driven entrepreneurship ecosystem in Houston, according to a news release, to focus on energy innovation. Greentown Labs, MIT’s Martin Trust Center for Entrepreneurship, and universities across Texas — including The founding institutions of TEX-E are Rice University, Texas A&M University, Prairie View A&M University, University of Houston, and The University of Texas at Austin — are collaborating on the project.

“Houston has long been known as the energy capital of the world, but to lead the world’s energy transition, the city must create a strong, vibrant innovation ecosystem to support the next generation of entrepreneurs and energy companies,” says Lara Cottingham, chief of staff at Greentown Labs, in the news release. “TEX-E will build upon Texas universities’ deep and long-standing connections to the energy industry by helping to attract and retain the world-class talent needed to supercharge Houston’s innovation ecosystem.”

The program, though based in Texas, will integrate both Greentown Labs locations, providing students with access to mentorship with incubator startups, networking events, career opportunities, and cross-learning with MIT.

“Boston and Houston might seem like an odd pairing, but they complement one another beautifully,” says Ben Soltoff, ecosystem builder and entrepreneur in residence at the Martin Trust Center for MIT Entrepreneurship, in the release. “The Boston area has a strong community-driven ecosystem around climate innovation, including MIT’s pioneering Climate and Energy Ventures Course in Cambridge, which has spawned over 30 companies. But often when MIT startups need to scale up, they look towards Texas, where they can find talent, space, and industry knowhow in spades.

"Together, these two regions are unstoppable,” he adds.

The five schools are just the beginning for the program, which plans to expand the collaboration over time. Locally, Houston area schools have collaborated with Greentown Houston since its opening over a year ago.

“The TEX-E collaboration will provide valuable opportunities to our students, and Houston is a natural location to create such an ecosystem,” says Ramanan Krishnamoorti, vice president for energy and innovation at the University of Houston, in the release. “Training new talent and supporting their pursuit of innovative ideas are vital in addressing the growing global need for affordable, reliable, and environmentally sustainable energy.”

For more information, students and educators should sign up for the TEX-E newsletter and attend an upcoming event at Greentown Houston. The next event at the incubator is the Climatetech Summit on November 2.

In addition to the $5 million partnership, Shell also pledged another $1 million to create a career pipeline for PVAMU students. Photo via Wikipedia Commons

Shell forms $5M carbon capture research partnership with Houston-area university

struck a deal

Houston-based Shell Global Solutions and Prairie View A&M University signed a $5 million partnership this week that aims to foster innovative and effective carbon dioxide utilization and carbon capture methods.

The five-year research agreement will be headquartered out of the Historically Black University's College of Agriculture and Human Sciences. A portion of the $5 million will go toward building new infrastructure and state-of-the-art greenhouses on the university's nearly 700 acres of land devoted to farm research.

Shell staff members are also slated to collaborate on research projects developed at the site.

In addition to the $5 million partnership, Shell also pledged another $1 million to create a career pipeline for PVAMU students. The funds will go toward university infrastructure, retention programs, and work experience opportunities.

"[Shell's] comprehensive approach — involving infrastructure, research collaboration, internships and ongoing staff involvement — is especially welcome," Ruth J. Simmons, president of PVAMU, said in a statement.

The new research program is funded through Shell's Projects & Technology organization, which "helps to ensure that neither people nor nature are harmed during the construction and operation of Shell’s facilities, and it supports Shell’s carbon-management activities," according to the company's website.

Shell has launched more than 220 research and development projects through this branch of the organization over the years.

In 2019, the energy giant committed to a $10 million arrangement to launch the Carbon Hub at Rice University, a research initiative aimed at developing zero-emissions technologies. The hub made its first seven seed grants in August.

Shell is also an industry partner on the University of Houston's Data Science for Energy Transition project.

The partnership also marks a milestone for PVAMU as the first significant partnership under the university's new classification as a Research 2 Institution, according to PVAMU's website. The university attained its R2 Carnegie Classification, the second-highest ranking for research and higher education institutions in the country, earlier this month.

Charles Butt has provided funding for a permanent scholarship fund. Photo courtesy of Texas State History Museum Foundation

H-E-B leader gifts $5 million to historic Houston-area university for future students

HEB and PVAMU

The leader of the Lone Star State’s beloved H-E-B has bestowed a monumental gift upon a historic Houston-area university.

On November 17, Prairie View A&M University announced that H-E-B chairman Charles Butt — one of America’s favorite CEOs and member of one of Texas’ richest families — has donated $5 million to create Founders Scholarships for incoming PVAMU students.

“The $5 million gift will provide a permanent endowment to support students today and in the coming years,” a release notes. “Initially generating approximately $200,000 a year for scholarships, the fund will grow significantly in coming years, making even more available to support students.”

The scholarships will be available to students from public high schools in Texas graduating in the top quartile of their class, the release says. They must be incoming first-year students, enrolled in a full-time course load, and as scholarship recipients, they will benefit from “enrichment opportunities unique to their [Founders Scholarships] cohort.”

Scholarship disbursements will begin in fall 2022, a spokesperson confirms; the number of initial scholarships available has not been revealed.

“Charles Butt has been amazingly generous to our university. He has shown time and time again that he genuinely cares about the opportunities afforded to students at PV. We are indebted to him for his grace and his humanity,” says Ruth Simmons, president of PVAMU, in the release.

Prairie View A&M University is the second-oldest public institution of higher learning in the state and is one of Texas’ historically Black universities. It is located approximately 50 miles northwest of Houston and has a current enrollment of more than 8,000 undergraduate and graduate students.

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This article originally ran on CultureMap.

Mackenzie Scott has gifted tens of millions to Houston-area organizations and institutions, and her latest gift is to Prairie View A&M University. Photo courtesy of Prairie View A&M

Philanthropist gifts historic $50 million to Houston-area university

major gift

Historically Black universities have traditionally been overshadowed and underfunded compared to their non-Black collegiate counterparts. But now, a major public figure's game-changing gift has helped level the playing field for a beloved Houston-area school.

Noted author and philanthropist MacKenzie Scott (many know her as the former wife of Amazon CEO and billionaire Jeff Bezos) has donated a massive $50 million to Prairie View A&M University, the institution announced on December 15. The gift is the largest one-time endowment in the school's 144-year history.

Under terms of the donation, the funds can be used at the discretion of the president to support the needs of the university, per a press release. Administrators have chosen to designate $10 million of the total to create the Panther Success Grant Program, an effort to assist juniors and seniors with unpaid balances created by the financial challenges posed by COVID, the school announced.

"This is a historic gift for Prairie View, coming at a time when the university had already decided and begun to invest heavily in key areas to strengthen its academic programs and improve student success," said Ruth J. Simmons, president of Prairie View, in a statement. "The timing of this gift could therefore not be better."

Simmons adds in a statement that she had been in contact with Scott "about a matter not involving Prairie View," and thus was "stunned and, for a time speechless" when Scott's assistant phoned and revealed the donation.

Another whopping gift from Scott includes $18 million to the Greater Houston YMCA.

In a post on Medium, Scott notes that she and her advisers have disbursed over $4 billion in gifts to 384 organizations across all 50 states, Puerto Rico, and Washington D.C. over the last four months. This is in effort to "accelerate my 2020 giving through immediate support to people suffering the economic effects of the crisis," Scott writes.

Scott's generosity includes myriad Texas organizations and groups, including:

  • Easterseals of Greater Houston
  • Easterseals Rehabilitation Center, San Antonio
  • East Texas Food Bank
  • El Pasoans Fighting Hunger
  • Feeding the Gulf Coast
  • South Texas Food Bank
  • Southeast Texas Food Bank
  • Goodwill Houston
  • Goodwill Industries of Dallas
  • Goodwill Industries of East Texas
  • Goodwill Industries of Fort Worth
  • Goodwill Industries of San Antonio
  • Heart of Texas Goodwill Industries
  • Meals on Wheels Central Texas
  • Meals on Wheels Montgomery County
  • Meals on Wheels North Central Texas
  • Texas A&M International University
  • United Way of El Paso County
  • United Way of San Antonio and Bexar County
  • YMCA of Greater Houston
  • YMCA of Metropolitan Dallas
  • YWCA El Paso del Norte Region
  • YWCA Greater Austin
  • YWCA of Lubbock
  • YWCA San Antonio
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This article originally ran on CultureMap.

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Baylor College of Medicine launches VC fund to invest in biotech startups

fresh funding

Houston’s Baylor College of Medicine just unveiled a new venture capital fund that backs early-stage biotech startups—and it’s already made its first investment.

BCM Legacy Fund I, funded by philanthropies, invested an undisclosed amount in Houston biotech startup Nemea Therapeutics. Nemea, a spinout of the Baylor College of Medicine and Germany’s Lead Discovery Center, is developing an oral drug to treat metastatic triple-negative breast cancer that no longer responds to currently available therapies.

This type of aggressive cancer spreads from the breast to other areas of the body, such as the bones, liver, lungs or brain. Roughly 38,000 to 57,000 Americans are diagnosed each year with metastatic triple-negative breast cancer. One study showed about half of patients survive past the one-year mark following diagnosis and about one-third survive two years.

“Baylor College of Medicine’s laboratories produce discoveries with the potential to change patients’ lives, and too many of them stall where academic funding ends and private investment has not yet begun,” Dr. Jakub Tolar, president, CEO and executive dean of the Baylor College of Medicine, said in a press release. “The BCM Legacy Fund fills that gap, giving our scientists a path to advance their discoveries to patients.”

The National Institutes of Health awards more than $36 billion per year for biomedical research in the U.S., Baylor said. But some biomedical discoveries “never leave the starting line because they don’t yet fit the economics of venture capital,” the college said.

“The forefront of a new model”

The BCM Legacy Fund aggregates philanthropic capital from private foundations and donor-advised funds. It then invests in startups so they can move beyond that starting line and into later-stage investment rounds. The Greater Houston Community Foundation is the fund’s philanthropic partner.

“It’s exciting to be on the forefront of a new model for philanthropic capital,” said Houston entrepreneur and investor Burton Hanson, managing partner of the fund.

“Not only do we hope to solve a real problem by advancing these therapies to the patients who need them most, but we also hope this model will inspire others in the city and beyond toward philanthropic creativity and a posture of ‘I sacrifice; we win.’”

The fund expects to invest in about 15 early-stage startups over a five-year span. Baylor declined to divulge the amount of money in the fund and the size of the investment in Nemea.

Nemea’s “world-class chemistry”

Hanson oversees the Baylor fund alongside Chicago investor Steve Lehmann, who led the University of Chicago’s Innovation Fund.

Lehmann said Nemea, the fund’s first portfolio company, “has world-class chemistry, Baylor biology, and patients with no good options. Our job is to fund the experiments that carry it to the next handoff, so that industry and later-stage investors can take it from there.”

Based at Houston’s massive Texas Medical Center, Nemea plans to start clinical trials next year in collaboration with Baylor’s Lester and Sue Smith Breast Center.

Nemea previously received $9 million from the Lead Discovery Center and a $1.6 million grant from Baylor. Last year, the startup said it was seeking $25 million to $30 million in seed and Series A funding.

Debra McCoy of Houston, a former managing director at BlackRock and former partner at Bain & Co., and Paul Thomas, co-founder and CEO of Spring-based benefits manager Luscinia Health, sit on the Baylor fund’s governing board. Dr. Paul Klotman, former president, CEO and executive dean of Baylor, is a senior strategic adviser.

How does the fund find investment targets?

The Baylor Legacy Fund relies on two tools to help unearth early-stage biotech startups:

  • High-resolution “innovation maps” of research institutions. These maps surface hidden clusters of innovation, identify rising-star researchers and tie pockets of “innovation supply” at Baylor to areas of “innovation demand” in biotech.
  • AI-enhanced due diligence. AI agents assist with due diligence of early-stage biotech startups. The fund says the platform “distills the frameworks we’ve developed over a decade of teaching and investing into a flexible … diligence environment.”

MD Anderson unveils $3.4B expansion with two new Houston cancer care facilities

major expansion

The cutting edge of cancer-fighting technology and science is getting even sharper after MD Anderson announced last week that it will open two new facilities in the Texas Medical Center within the next five years. Inspiration Tower and Prism will expand MD Anderson’s annual patient load in the TMC to 250,000 annually and will incorporate a variety of new techniques.

The $3.4 billion project will add 2 million square feet to MD Anderson's TMC footprint, bringing its total campus size to 22 million square feet by 2032. Located at the corner of Fannin Street and Holcombe Boulevard, the cancer center says the two new facilities will serve as its new "front door" to the TMC.

“Every detail of these buildings, from the technology to the treatment rooms, was designed around our patients who will receive their care in them and our employees who will work in them. The facilities will serve as a physical representation of hope for the patients and their families who will walk through the doors,” Dr. Jeffrey E. Lee, president ad interim of UT MD Anderson, said in a news release. “Inspiration Tower and Prism are the future of cancer care, and we are grateful for the longstanding support and guidance we’ve received from the UT System Board of Regents to bring these projects to life. These facilities are part of the most impactful capital expansion in UT MD Anderson’s history.”

Prism is especially exciting as it will represent fully half of the linear accelerator treatment in the TMC. Linear accelerator is a radiation treatment that uses magnetically charged fields to deliver targeted external radiation therapy, like shooting cancer with a rail gun. The treatment is safer and has fewer side effects than older radiation treatments.

In addition, Prism will contain 12 MRI machines, four CT scanners, two PET-CT units, 18 radiation vaults and seven radiation simulators. Patient comfort has also been put at a premium with multiple gardens and roof overlooks.

“Every patient we treat deserves an environment that reflects the excellence of the care they receive at UT MD Anderson,” Chris McKee, executive vice president and chief strategy officer at UT MD Anderson, added in the release. “Our new facilities will be innovative, agile, adaptable and beautiful, and they will allow us to care for more patients, more effectively – in an environment that enhances healing and well-being. We are building for our future and for every patient who will be counting on us.”

Prism is slated to open in 2030.

Inspiration Tower will have 25 floors of surgical, diagnostic, and treatment services. At 1.4 million square feet, it’s currently expected to be the largest cancer-specific treatment facility in the United States. The tower will be divided into units for specific types of cancer, making it easy to integrate the advancing research being done all over Houston.

Like Prism, Inspiration Tower is specifically designed to offer comfort and reassurance, with more garden space, terraces, and beautiful scenery to ease patient distress. It is expected to open in 2032.

Tesla will pull the plug on Cybertruck production at Texas factory in 2027

Tesla Talk

Tesla’s Cybertruck, the hulking, stainless-steel pickup that inspired devotion and derision with its science-fiction looks, will cease production next year.

CEO Elon Musk announced the model’s demise Friday, November 6, with a curt post on X, his social media site, simply noting production of the vehicle “will be winding down” around the middle of 2027 at its facility outside Austin, Texas. Musk said the move was to allow increased production of its Cybercab robotaxi.

For the Cybertruck, a pet project of Musk who insisted it was Tesla’s best product, it marks an unceremonious end to one of the auto industry’s most ballyhooed debuts.

“Few vehicles in history have generated as much attention,” said Armen Hareyan, whose Torque News site covers autos. “The Cybertruck became a cultural symbol – loved, mocked and impossible to ignore.”

The Cybertruck rolled onto the scene in a dramatic unveiling in 2019, when a Tesla designer hurled a metal ball at the vehicle to demonstrate its supposedly unbreakable glass, only to see it shatter. He repeated the stunt on another window of the truck only to shatter that one, too.

Even as some critics scoffed, Musk was steadfast.

“I just wanted to make a futuristic battle tank — something that looks like it could come out of ‘Blade Runner’ or ‘Aliens’ or something like that but was also highly functional,” he told Automotive News. He called it “a better sports car than a Porsche 911” and “a better truck than an F-150.”

It struck some as the perfect vehicular reflection of the brash, convention-busting Musk.

“A really controversial vehicle unveiled by a controversial individual into a market where none of the electric trucks have been able to really capture demand,” said Spencer Penn, a former Tesla executive who left the company before the Cybertruck’s launch and now heads software developer LightSource.

Penn remembered watching the unveiling and feeling initially revolted by the sight of the Cybertruck, calling its appearance “madness.” But the more he looked at it, the more his opinion changed. He signed up for a pre-sale reservation, though ended up not getting a Cybertruck when Musk’s promises of a price tag under $40,000 went unmet and the first trucks sold for double or more. Penn called the Cybertruck part of Tesla’s adventurous spirit that drives innovation.

“Some of these bets work and some of these bets don’t,” he said.

While the decision to end Cybertruck production may be driven by sales realities, it's also a reflection of Tesla’s shift to autonomous vehicles, on which Musk is betting the company’s future.

Musk once forecast he’d make 250,000 Cybertrucks a year. Kelley Blue Book estimated Tesla sold just 20,237 of the vehicles last year, down about half from the year prior. Sales through the end of September this year were down another 28%, according to Kelley Blue Book.

If the imposing, sharp-angled, dystopian appearance of the Cybertruck weren’t enough to turn many potential buyers away, Musk did so himself by allying with a panoply of right-wing figures, most notably U.S. President Donald Trump. He alienated some customers as his image morphed from eccentric innovator to polarizing force trading his billions for political influence.

Once-passionate Tesla drivers rushed to sell off their cars, or slapped stickers on the bumper declaring, “I bought this before Elon went crazy.” Organizers staged demonstrations outside Tesla showrooms and urged investors to dump shares of the company’s stock. Anger spilled into violence, with Molotov cocktails hurled at Tesla vehicles, charging stations set ablaze, and dealerships covered in graffiti.

Lovers of the Cybertruck became targets, too, subjected to shouts of “Nazi!” and extended middle fingers.

Ross Blankenship is one of them. When he first laid eyes on the Cybertruck, he felt transported to a world from his childhood, when he would play “Halo,” the sci-fi video game. He had to have it.

“I had that sort of child in me wanting to be part of something cool that would change the future of automotive,” Blankenship said in a call from his Cybertruck as he drove through Sunnyside, Colorado. Even as Blankenship found he agreed with Musk on politics, he hated seeing a vehicle he loved turned into a political symbol. “I never bought it for any other reason than the fascination with the future technology of trucks … so that was a little heartbreaking.”

He would buy another Cybertruck again in a heartbeat, calling its end “a sad moment.”