3+ Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Sarah Hein of March Biosciences, Sean Kelly of Amperon, Donnell Debnam Jr. of the Google in Residence program, and the 2023 Houston Innovation Awards judges. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries, from biotech to energy software, recently making headlines in Houston innovation — plus the decision makers for the Houston Innovation Awards.

Sarah Hein, CEO and co-founder of March Biosciences

Early-stage cell therapy startup March Biosciences has partnered with CTMC. Photo via march.bio

Named in part after one of the best months out of the year for Houstonians, March Biosciences has entered into a uniquely Houston partnership. Sarah Hein, CEO and co-founder of the cancer immunotherapy startup, met her co-founders at the TMC Accelerator for Cancer Therapeutics.

“It's a perfect example of the opportunities here in Houston where you can go from bench to bedside, essentially, in the same institution. And Baylor has been particularly good at that because of the Center for Cell and Gene Therapy,” says Hein.

The company recently announced a partnership with another Houston institution, CTMC. Read more.

Sean Kelly, CEO and co-founder of Amperon

It's payday for a startup that's improving analytics for its energy customers. Photo via Getty Images

Amperon Holdings Inc. raised $20 million in its latest round of funding in order to accelerate its energy analytics and grid decarbonization technology.

The fresh funding will support the company in evolving its platform that conducts electricity demand forecasting to a comprehensive data analytics solution.

“The energy transition is creating unprecedented market volatility, and Amperon is uniquely positioned to help market participants better navigate the transitioning grid – both in the U.S. and as we expand globally,” Sean Kelly, CEO and co-founder of Amperon, says. Read more.

Donnell Debnam Jr., instructor in the Google in Residence program

Thanks to Google, Donnell Debnam Jr. is helping train future software engineers at Prairie View A&M University. Photo via LinkedIn

Computer science students at Prairie View A&M University are gaining firsthand knowledge this semester from a Google software engineer.

As an instructor in the Google in Residence program, Donnell Debnam Jr. is helping train future software engineers — and other potential tech professionals — who are enrolled this fall in Prairie View A&M’s introductory computer science course. Fifty-four students are taking the class.

“I participated in the Google in Residence program as a student, and I am honored to return as an instructor,” says Debnam. “This innovative program was created to support greater diversity in the tech industry, and as an instructor, I have the privilege of helping the next generation of software engineers create a more inclusive culture within the STEM fields.” Read more.

2023 Houston Innovation Awards judges

Bonus innovators to know: The 10 Houstonians deciding the finalists and winners for this year's Houston Innovation Awards. Photos courtesy

Ten Houstonians are in the hot seat for deciding the best companies and individuals in Houston's innovation ecosystem.

InnovationMap has announced its 2023 Houston Innovation Awards judging panel, which includes startup founders, nonprofit leaders, investors, corporate innovators, and more.

Meet the 10 selected judges who will evaluate applications from the nearly 400 nominations that were submitted this year. Read more.

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Thanks to Google, Donnell Debnam Jr. is helping train future software engineers at Prairie View A&M. Photo via LinkedIn

Google program plants software expert at Houston-area university

meet the faculty

Computer science students at Prairie View A&M University are gaining firsthand knowledge this semester from a Google software engineer.

Prairie View A&M is one of 14 historically black colleges and universities (HBCUs) and Hispanic-serving schools that are benefiting this fall from the Google residency program. Since being founded in 2013, the program has enabled more than 8,000 college students across the country to absorb knowledge from Google tech professionals.

The Google program addresses a nationwide gap in tech diversity.

A 2023 report from CompTIA, a trade group for the tech industry, shows Black professionals make up 12 percent of the U.S. workforce but eight percent of tech occupations, while Hispanic professionals represent 17 percent of the U.S. workforce but eight percent of tech occupations.

Prairie View A&M, an HBUC, is one of two Texas universities in this fall’s program. The other is the University of Texas at El Paso, a Hispanic-serving school. The main campus of Prairie View A&M is roughly 45 miles northwest of Houston.

Google says Debnam is equipping students at Prairie View A&M “with the skills needed to enter the workforce, such as fundamental coding concepts, how to debug, and how to prepare for technical interviews.”

As a student in 2017, Debnam participated in the Google residency program at Hampton University, an HBCU in Hampton, Virginia. In a LinkedIn post, Debnam wrote that since then, “I always said to myself and others that if I could figure out a way to get into Google someday, I would make it a priority to try to be part of this program.”

After completing two Google internships and earning a bachelor’s degree in computer science from Hampton, Debnam joined the tech giant as a full-time software engineer in 2021.

“If you know me, you know I have a passion for tech, but an even deeper passion for working with students and being a resource in any way possible,” he wrote on LinkedIn.

A new program is launching to support the next generation of energy innovators. Photo via greentownlabs.com

Greentown Labs launches student-driven entrepreneurship program in Texas

back to school

The country's largest climatetech startup incubator and several schools are teaming up to prepare the next generation of clean energy innovators.

Greentown Labs, based in Boston and Houston, announced its new Texas Entrepreneurship Exchange for Energy (TEX-E) this week. The collaborative initiative aims to strengthen the student-driven entrepreneurship ecosystem in Houston, according to a news release, to focus on energy innovation. Greentown Labs, MIT’s Martin Trust Center for Entrepreneurship, and universities across Texas — including The founding institutions of TEX-E are Rice University, Texas A&M University, Prairie View A&M University, University of Houston, and The University of Texas at Austin — are collaborating on the project.

“Houston has long been known as the energy capital of the world, but to lead the world’s energy transition, the city must create a strong, vibrant innovation ecosystem to support the next generation of entrepreneurs and energy companies,” says Lara Cottingham, chief of staff at Greentown Labs, in the news release. “TEX-E will build upon Texas universities’ deep and long-standing connections to the energy industry by helping to attract and retain the world-class talent needed to supercharge Houston’s innovation ecosystem.”

The program, though based in Texas, will integrate both Greentown Labs locations, providing students with access to mentorship with incubator startups, networking events, career opportunities, and cross-learning with MIT.

“Boston and Houston might seem like an odd pairing, but they complement one another beautifully,” says Ben Soltoff, ecosystem builder and entrepreneur in residence at the Martin Trust Center for MIT Entrepreneurship, in the release. “The Boston area has a strong community-driven ecosystem around climate innovation, including MIT’s pioneering Climate and Energy Ventures Course in Cambridge, which has spawned over 30 companies. But often when MIT startups need to scale up, they look towards Texas, where they can find talent, space, and industry knowhow in spades.

"Together, these two regions are unstoppable,” he adds.

The five schools are just the beginning for the program, which plans to expand the collaboration over time. Locally, Houston area schools have collaborated with Greentown Houston since its opening over a year ago.

“The TEX-E collaboration will provide valuable opportunities to our students, and Houston is a natural location to create such an ecosystem,” says Ramanan Krishnamoorti, vice president for energy and innovation at the University of Houston, in the release. “Training new talent and supporting their pursuit of innovative ideas are vital in addressing the growing global need for affordable, reliable, and environmentally sustainable energy.”

For more information, students and educators should sign up for the TEX-E newsletter and attend an upcoming event at Greentown Houston. The next event at the incubator is the Climatetech Summit on November 2.

In addition to the $5 million partnership, Shell also pledged another $1 million to create a career pipeline for PVAMU students. Photo via Wikipedia Commons

Shell forms $5M carbon capture research partnership with Houston-area university

struck a deal

Houston-based Shell Global Solutions and Prairie View A&M University signed a $5 million partnership this week that aims to foster innovative and effective carbon dioxide utilization and carbon capture methods.

The five-year research agreement will be headquartered out of the Historically Black University's College of Agriculture and Human Sciences. A portion of the $5 million will go toward building new infrastructure and state-of-the-art greenhouses on the university's nearly 700 acres of land devoted to farm research.

Shell staff members are also slated to collaborate on research projects developed at the site.

In addition to the $5 million partnership, Shell also pledged another $1 million to create a career pipeline for PVAMU students. The funds will go toward university infrastructure, retention programs, and work experience opportunities.

"[Shell's] comprehensive approach — involving infrastructure, research collaboration, internships and ongoing staff involvement — is especially welcome," Ruth J. Simmons, president of PVAMU, said in a statement.

The new research program is funded through Shell's Projects & Technology organization, which "helps to ensure that neither people nor nature are harmed during the construction and operation of Shell’s facilities, and it supports Shell’s carbon-management activities," according to the company's website.

Shell has launched more than 220 research and development projects through this branch of the organization over the years.

In 2019, the energy giant committed to a $10 million arrangement to launch the Carbon Hub at Rice University, a research initiative aimed at developing zero-emissions technologies. The hub made its first seven seed grants in August.

Shell is also an industry partner on the University of Houston's Data Science for Energy Transition project.

The partnership also marks a milestone for PVAMU as the first significant partnership under the university's new classification as a Research 2 Institution, according to PVAMU's website. The university attained its R2 Carnegie Classification, the second-highest ranking for research and higher education institutions in the country, earlier this month.

Charles Butt has provided funding for a permanent scholarship fund. Photo courtesy of Texas State History Museum Foundation

H-E-B leader gifts $5 million to historic Houston-area university for future students

HEB and PVAMU

The leader of the Lone Star State’s beloved H-E-B has bestowed a monumental gift upon a historic Houston-area university.

On November 17, Prairie View A&M University announced that H-E-B chairman Charles Butt — one of America’s favorite CEOs and member of one of Texas’ richest families — has donated $5 million to create Founders Scholarships for incoming PVAMU students.

“The $5 million gift will provide a permanent endowment to support students today and in the coming years,” a release notes. “Initially generating approximately $200,000 a year for scholarships, the fund will grow significantly in coming years, making even more available to support students.”

The scholarships will be available to students from public high schools in Texas graduating in the top quartile of their class, the release says. They must be incoming first-year students, enrolled in a full-time course load, and as scholarship recipients, they will benefit from “enrichment opportunities unique to their [Founders Scholarships] cohort.”

Scholarship disbursements will begin in fall 2022, a spokesperson confirms; the number of initial scholarships available has not been revealed.

“Charles Butt has been amazingly generous to our university. He has shown time and time again that he genuinely cares about the opportunities afforded to students at PV. We are indebted to him for his grace and his humanity,” says Ruth Simmons, president of PVAMU, in the release.

Prairie View A&M University is the second-oldest public institution of higher learning in the state and is one of Texas’ historically Black universities. It is located approximately 50 miles northwest of Houston and has a current enrollment of more than 8,000 undergraduate and graduate students.

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This article originally ran on CultureMap.

Mackenzie Scott has gifted tens of millions to Houston-area organizations and institutions, and her latest gift is to Prairie View A&M University. Photo courtesy of Prairie View A&M

Philanthropist gifts historic $50 million to Houston-area university

major gift

Historically Black universities have traditionally been overshadowed and underfunded compared to their non-Black collegiate counterparts. But now, a major public figure's game-changing gift has helped level the playing field for a beloved Houston-area school.

Noted author and philanthropist MacKenzie Scott (many know her as the former wife of Amazon CEO and billionaire Jeff Bezos) has donated a massive $50 million to Prairie View A&M University, the institution announced on December 15. The gift is the largest one-time endowment in the school's 144-year history.

Under terms of the donation, the funds can be used at the discretion of the president to support the needs of the university, per a press release. Administrators have chosen to designate $10 million of the total to create the Panther Success Grant Program, an effort to assist juniors and seniors with unpaid balances created by the financial challenges posed by COVID, the school announced.

"This is a historic gift for Prairie View, coming at a time when the university had already decided and begun to invest heavily in key areas to strengthen its academic programs and improve student success," said Ruth J. Simmons, president of Prairie View, in a statement. "The timing of this gift could therefore not be better."

Simmons adds in a statement that she had been in contact with Scott "about a matter not involving Prairie View," and thus was "stunned and, for a time speechless" when Scott's assistant phoned and revealed the donation.

Another whopping gift from Scott includes $18 million to the Greater Houston YMCA.

In a post on Medium, Scott notes that she and her advisers have disbursed over $4 billion in gifts to 384 organizations across all 50 states, Puerto Rico, and Washington D.C. over the last four months. This is in effort to "accelerate my 2020 giving through immediate support to people suffering the economic effects of the crisis," Scott writes.

Scott's generosity includes myriad Texas organizations and groups, including:

Easterseals of Greater Houston
Easterseals Rehabilitation Center, San Antonio
East Texas Food Bank
El Pasoans Fighting Hunger
Feeding the Gulf Coast
South Texas Food Bank
Southeast Texas Food Bank
Goodwill Houston
Goodwill Industries of Dallas
Goodwill Industries of East Texas
Goodwill Industries of Fort Worth
Goodwill Industries of San Antonio
Heart of Texas Goodwill Industries
Meals on Wheels Central Texas
Meals on Wheels Montgomery County
Meals on Wheels North Central Texas
Texas A&M International University
United Way of El Paso County
United Way of San Antonio and Bexar County
YMCA of Greater Houston
YMCA of Metropolitan Dallas
YWCA El Paso del Norte Region
YWCA Greater Austin
YWCA of Lubbock
YWCA San Antonio

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This article originally ran on CultureMap.

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Generation Park lands new facility to scale xeno-organ production

Organ innovation

Maryland-based United Therapeutics Corp. has opened a new 77,448-square-foot facility to manufacture xeno-organs in Northeast Houston’s growing biotech hub, Generation Park.

The new Houston location is United Therapeutics’ third Designated Pathogen-Free (DPF) site, named for transplant pioneers Dr. Bartley P. Griffith and Dr. Robert A. Montgomery. The company says the new facility will enable it to scale commercial production of its xeno-organs once they receive regulatory approval.

An existing DPF facility in Virginia is supporting clinical trials for the xeno-organs, and a third site in Minnesota will also focus on commercialization with the Houston site, according to the company.

Xeno-organs are organs taken from a non-human animal source and transplanted, implanted or infused into a human recipient.

Currently, United Therapeutics is advancing clinical trials to support a Biologics License Application with the U.S. Food and Drug Administration for its investigational-stage xenotransplantation, UKidney, UThymoKidney and UHeart products. The products all involve working with the genes from humans and pigs.

In 2025, Chron.com reported the company was working to construct an estimated $96 million facility to breed genetically engineered animals. Head of investor relations at United Therapeutics Dewey Steadman told the Houston Business Journal in 2025 that the pigs’ DNA will be edited. In November 2024, a 53-year-old woman in Alabama received a transplanted kidney from UKidney that had 10 gene edits. She had the transplant removed in April 2025, after her body rejected it.

The Dr. Bartley P. Griffith and Dr. Robert A. Montgomery Xenograft Production Facility requires a “strictly controlled, biosecure barrier environment, including air filtration, filtered water, filtered feed supplies, and state-of-the-art decontamination entryways,” according to the company. Being pathogen-free means it includes calibrated air and water conduits to support the transplantability of xenograft products and to prevent contamination. For energy considerations, the building also features solar arrays.

“With our third xenograft production facility now open and clinical trials underway, United Therapeutics is moving closer to its goal of providing transplantable organs to the people who need them,” Martine Rothblatt, chairperson and CEO of United Therapeutics, said in a news release. “It is fitting that this facility is named for Dr. Griffith and Dr. Montgomery, whose first-in-human surgeries turned xenotransplantation from a theoretical possibility into a clinical reality.”

The facility, which wrapped construction in August, is located at 11848 Common Dock Dr. in Generation Park, which will house manufacturing sites for pharmaceutical heavyweights Bristol Myers Squibb and Eli Lilly. Last fall, Eli Lilly tapped Generation Park for its $6.5 billion manufacturing plant, and Bristol Myers Squibb made a $2.3 billion investment in August to bring its state-of-the-art site to the master-planned commercial district.

Elon Musk's SpaceX reports profit as AI and satellite businesses booms

Booming Business

SpaceX reported a bigger quarterly profit than expected on Tuesday, October 20, as its satellite communications and artificial intelligence businesses boomed.

The company, run by Elon Musk, posted a profit for the three months through September 2026 of $4.4 billion, or 35 cents per share, reversing a year-ago loss and easily topping Wall Street's expectations. Revenue soared to $14.6 billion, up 161%.

On a conference call with analysts, Musk suggested a merger with his electric car company Tesla might be in the works, something that has been rumored for months. He said both companies formed “special committees” of independent directors to discuss the issue, though he played down the chances of an imminent deal.

“Some people out there assume that a SpaceX and Tesla merger is a certainty,” he said. “I think that would be overstating it.”

The AI business became SpaceX's largest by revenue in the third quarter, although the Starlink satellite service remains the biggest profit generator.

“They beat across all metrics and the Starlink business looks to be accelerating,” said Dan Ives, an analyst at Yorkville Ives. “This is just what (Wall) Street wanted.”

The stock rose 7.5% in after-hours trading.

Musk also told analysts that for next month's launch of its Starship rocket, SpaceX will attempt to grab both the booster and ship with mechanical arms upon return to base, a key step toward demonstrating it can reuse the massive spacecraft.

“The only way that we can extend consciousness beyond Earth on a sustained basis is with a fully reusable orbital launch vehicle,” Musk said, calling the attempt, if successful, “a massive technology milestone.”

SpaceX hopes to get Starship on a regular launch pattern in preparation for NASA's upcoming lunar missions.

The company already has huge contracts with the federal government, and House Democrats have called for investigations into those contracts and Musk’s work with the Department of Government Efficiency. Musk has spent $276 million since July in support of Republican candidates.

In a filing for its initial public offering in June, SpaceX warned that a change in control of Congress could have a “material and adverse impact on our growth and competitive position.”

Musk recently drew criticism from politicians in Washington after speeds for a military version of SpaceX's satellite communications service were slowed for Ukraine following President Donald Trump's deal to get more diesel oil from Russia amid a push to end the war. The Wall Street Journal reported Tuesday that it was Musk who ordered the slowdown, impeding Ukraine’s use of drones along the front. SpaceX did not immediately respond to an Associated Press request for comment on the Journal story.

Both Trump and Musk have denied responsibility for the slowdown.

As midterm elections near, Musk on Monday promised to give one share of SpaceX to “every kid in America” next year, though he provided no details on how the distribution would be carried out. With communities nationwide protesting the construction of large data centers and concerns about AI safety, AI companies are trying to build goodwill. Anthropic pledged to commit 5% of its shares to a new “public benefit” fund.

SpaceX shares have been under pressure over concerns that the company was spending too much on major projects to compete with rivals such as Anthropic. The company said capital expenditures totaled $19.6 billion last quarter, nearly triple the figure from a year earlier, and it forecast spending would grow to $35 billion to $40 billion in the current quarter.

Shares of SpaceX closed Tuesday at $147.79, down from a peak near $201 after its IPO, which made Musk the world’s first trillionaire at the time. But the share prices for SpaceX and Tesla have since dropped, reducing his net worth to $925 billion, according to Forbes magazine.

Tesla reports third-quarter financial results Wednesday. Last week, Tesla unveiled a new Roadster sports car that in some versions may include thrusters allowing it to briefly fly using SpaceX technology — though experts say anything usable for drivers is a long shot.

These 5 trailblazing Houston startups are leading the energy transition

meet the finalists

Houston is home to a growing number of startups reshaping what it means to be called the "Energy Capital of the World."

As part of the 2026 Houston Innovation Awards, our Energy Transition Business category honors those innovative startups that are providing solutions within renewables, climatetech, clean energy, alternative materials, circular economy and more.

Five clean energy startups have been named finalists for the 2026 award. The finalists, selected by our esteemed panel of judges, range from a lower-emission steel producer to a diagnostics platform developer working to support batteries used in data centers.

Read more about these innovative businesses, their initiatives, and their inspirational founders below. The 2026 winners will be announced on InnovationMap.com in mid-November.

Capwell Services

Methane capture company Capwell Services works to eliminate vented oil and gas emissions economically for operators. According to the company, methane emissions are vented from most oil and gas facilities due to safety protocols, and operators are not able to capture the gas cost-effectively, leading operators to emit more than 14 million metric tons of methane per year in the U.S. and Canada. Founded in 2022, Capwell specializes in low and intermittent flow vents for methane capture.

The company began as a University of Pennsylvania senior design project led by CEO Andrew Lane. It has since participated in programs with Greentown Labs, the Rice Clean Energy Accelerator and the Creative Destruction Lab Energy Cohort at Texas A&M University. The company moved to Houston in 2023 and raised a pre-seed round. It deployed two commercial units this year, according to its application.

FlowCellutions

Energytech startup FlowCellutions is developing a chemistry-agnostic diagnostics platform for flow and metal-air batteries supporting data centers and critical infrastructure. The platform is designed to help reduce operating costs, prevent failures and costly downtime, and extend battery lifetime from approximately seven years to more than 30 years. It has deployed four paid pilots and plans to take insights from the programs to develop its next-gen sensor platform technology.

CEO Becca Segel founded the company in 2022. It is a member of Greentown Labs, and Segel was a 2025 Activate Fellow. The company has raised over $2 million in non-dilutive funding and received a $1.5 million NSF SBIR Fast-Track award earlier this year.

Hertha Metals

Hertha Metals produces lower-cost, lower-emission steel and high-purity iron. The company has developed a single-step process that uses natural gas as a direct reductant instead of metallurgical coal, which cuts production costs by more than 25 percent and emissions by up to 50 percent, according to the company. The same process produces high-purity iron needed for high-purity steels and rare earth magnets. The company says it aims to "re-industrialize America’s production of critical materials."

Hertha Metals was founded by CEO Laureen Meroueh in 2022 and emerged from stealth last year with more than $17 million in venture capital funding. The company closed a $133.65 million Series A this month and also broke ground on its $100M high-purity iron factory known as Chalyx in Conroe.

Mars Materials

Clean chemical manufacturing business Mars Materials is working to convert captured carbon into resources, such as carbon fiber and wastewater treatment chemicals. The company develops and produces its drop-in chemical products in Houston and uses an in-licensed process for the National Renewable Energy Lab to produce acrylonitrile, which is used to produce plastics, synthetic fibers, and rubbers.

Founded in 2019 by CEO Aaron Fitzgerald, CTO Kristian Gubsch, and vice president of operations Trey Sheridan, the company has secured over $7.2M in financing and is backed by Bill Gates’ Breakthrough Energy, Shell, Black & Veatch, and other organizations. It won in the Minority-founded Business Category in last year's Houston Innovation Awards.

Solidec

Chemical manufacturing company Solidec has developed autonomous generators that extract molecules from water and air and convert them into pure chemicals and fuels that are free of carbon emissions on-site, eliminating the need for transport, storage, and permitting. The company was founded around innovations developed by Rice University associate professor Haotian Wang.

The company was selected for the Chevron Technology Ventures’ Catalyst Program, Greentown Labs, NSF I-Corps and was part of the first cohort of the Activate Houston program. It won first place at the 2024 startup pitch competition at CERAWeek. Solidec was founded in 2023 by Wang, who serves as an advisor, CEO Ryan DuChanois, and CTO Yang Xia. It closed a $2.5 million seed round in 2025.

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