Grace Rodriguez, CEO and executive director of Impact Hub Houston, has a few weeks ahead of her. Courtesy of Grace Rodriguez

Impact Hub Houston — the local chapter of a nonprofit focused on supporting startups in the social impact space — has a lot on its plate this month.

Not only is next week The Houston Innovation Summit — the fourth annual week of entrepreneurship programming — as well as the second annual Climathon, but the organization has also just launched a new business incubator program.

Accelerate is a program that Impact Hub has offered across 17 international markets. Houston's new chapter already has a few Houston startups involved — including Potentia Workforce and McMac CX. Structured as an ongoing accelerator with mentorship, education, and support, the program is currently accepting new members.

"We actually sit down with each new Accelerate member and then go through a diagnostic interview to help them understand what stage they're at," says Grace Rodriquez, CEO and executive director of Houston Impact Hub. "And then we create a development strategy with them."

Whether the Accelerate member needs one-on-one mentorship, specialized education, or more, the program match makes each member's needs. EY is a network partner and — since everything is virtual — member companies have access to international experts through Impact Hub and its partners' networks.

"The ideal entrepreneur for the Accelerate membership is somebody who has already developed a solution — at least an MVP — for their social venture, whether it's a product or a service," Rodriguez says.

She cites Potentia as an example. The startup helps find jobs for adults with special needs, as well as educate corporations on how to work with and collaborate with these individuals. The company already has data and momentum, and the Accelerate program is helping the company to get to it's next stage.

"The idea is that we help people ladder up — no matter what stage you're at," Rodriguez says.

While growing the new program's membership — Rodriguez says it's her goal to get to 10 member companies my early next year — she's also focused on The Houston Innovation Summit and Impact Hub's Climathon.

The second annual Climathon, which begins Friday, November 13, has evolved since last year in a number of ways. First of all, it's completely virtual — which poses its own set of challenges and opportunities. Additionally, the event has several new partners — most of which didn't even exist in Houston last year, like Greentown Houston and Evolve Houston.

One of the biggest, most exciting changes for Rodriguez is the structure. While last year's event functioned as a hackathon, this year attendees can expect thought-provoking programming and collaboration.

"Last year, [Climathon] was directed at people who were more tech savvy," Rodriguez says. "What we found is people who are interested in climate action are a lot of times policy oriented or community activists and they don't know how they can plug into the tech space. It's more of an idea-a-thon. You don't have to develop a tech solution, but we can think about how we can activate more people for climate change."

Last year's Climathon took place during October. WIth it moving to November this year, it coincides with THIS, adding even more events to the week-long, impact-focused summit. THIS, which was designed to run alongside Global Entrepreneurship Week, also considers that week's themes, which are: education, ecosystems, inclusion, and policy.

"The focus on education and policy is really interesting to me — it's not just about tech and business anymore," Rodriguez says. "It's really about how we are supporting businesses in the face of the pandemic, climate change crises — floods, fires, hurricanes — the entire world is being affected by these crises. ... [We need to focus on] how we are making sure that people are aware of everything that's happening and how we can innovate solutions."

This week's episode of the Houston Innovators Podcast highlights 11 different entrepreneurs at a live recording at The Cannon Houston's grand opening event. Courtesy of Quy Tran/The Cannon

Meet the innovators working out of The Cannon Houston's brand new space

Houston innovators podcast episode 5

Last week, The Cannon Houston premiered its new digs in West Houston with a grand opening event attended by an incredible group of innovators, entrepreneurs, friends, family, and even puppies.

InnovationMap and the Houston Innovators Podcast had a presence at the festivities as well, which has allowed us to put together a special edition of the podcast. Rather than recording an interview with one entrepreneur in studio, this week's episode features 11 interviews with over a dozen innovators.

Here's who all you'll hear from — in order — in this episode:

  • Werner Winterboer of SapMok, a South African sustainable shoe making company that's looking to expand in Houston.
  • Brad Greer of DrySee, a liquid bandage company that's created a wetness indicator that allows for a patient to know if their bandage has been compromised thus preventing infection risks.
  • Chris Bayardo of Bayardo Safety LLC, a small compliance company that uses tech to optimize the oil and gas industry's compliance issues.
  • Dirk Van Slyke of Statistical Vision, a marketing consultancy that taps into data and metrics to help organizations take their company to the next level.
  • Aaron Knape of sEATz, an app that has perfected the mobile food and drink ordering process in stadiums.
  • Matt and Adam Woods of Skippermyboat, a tourism startup that helps travelers easily connect with boating adventures all over the world.
  • Mike T. Brown of Win-Win, a sports tech company that gamifies the donation process for causes supported by professional athletes.
  • Alex Taghi, Aimee Robert, and Jeffery Abel of Co-Counsel, the coworking concept for lawyers and attorneys.
  • Jeff Miller of Potentia, an education and staffing platform that helps place autistic employees with their right employer.
  • Drew Wadley with MiTyket, which has created a software that can prevent price gouging in the live entertainment industry.
  • Bret Bloch with Four Tower LLC, which provides integrated solutions for projects and operations.

Check out the episode below and subscribe wherever you get your podcasts.


The Cannon hosted a B2B pitch night, and all three companies have a mission to change the world. Courtesy of The Cannon

3 Houston entrepreneurs changing the world with their B2B startups

On purpose

I think it's safe to say that most B2B startups don't have sustainability or a mission-driven purpose at the core of their business model. In fact, it's probably safe to say that about any for-profit company of any size.

Three Houston entrepreneurs pitched their companies at The Cannon's recent B2B pitch night, and they all have something in common: They're not normal B2B startups. Each company has a mission to change the way we're doing something — from hiring to construction — in a way that's better for the world.

Natalie Goodman, founder and CEO IncentiFind

Courtesy of IncentiFind

Natalie Goodman realized there was a disconnect between builders and green incentives the government provides.

"The government is strapped — they have all this money that they want to give away, but not the (marketing) money to get the word out," Goodman told InnovationMap last month. "That's where IncentiFind stepped in."

IncentiFind is a portal for green incentives and works in three steps. First, you do a search for green incentives in your area — this part is completely free to the commercial developer or home owner. Next, the user might opt to pay IncentiFind to find the exact incentives for the project and submits the applications for the project. The final step is a promise of a 10 times return on investment.

A million green projects are completed in the United States each year, and IncentiFind is getting in front of that by forming partnerships with lenders, commercial developers, architects, etc., Goodman says to the crowd. Read more about IncentiFind here.

Jeff Miller, CEO of Potentia

Courtesy of The Cannon

The facts and figures are pretty startling. One-in-40 school-age children are on the autism spectrum and one-in-five college-educated autistic individuals don't have a job when they graduate, Jeff Miller says during his pitch at The Cannon. Miller, who has a long career in staffing around the world, founded his company Potentia to help correct this growing employment problem.

"We're seeking to help employers build their 21st century workforce at the intersection of technology, leadership, and, most specifically, the autism spectrum," he says.

Potentia is a technology-focused recruitment firm with resources and opportunities for applicants on the Autism spectrum. For Miller, it's personal. His 16-year-old son has autism, and Miller wants a world where his son can have access to employment opportunities around the world.

"I think we're in a position to improve this model here in Houston, and take it to other cities," Miller says. "The reality is this is a challenge that exists in every major city."

Kim Raath, co-founder of Topl

Courtesy of Topl

Sure, blockchain is a major buzzword nowadays, but for Topl co-founder Kim Raath it means having the ability to track the sustainability of a purchase. Topl's technology is able to tell you if your diamond ring came from a war-torn country or if your coffee's farmer was paid fairly.

Raath says she's seen an increased need for sustainable and transparent businesses that can prove their impact, but it's expensive to do that.

"These businesses are spending so much money on trying to prove this impact," Raath says in her pitch at The Cannon. "We have customers spending close to 15 percent in operational expenses just to be able to trace their growth."

The company, founded by three Rice University students, is growing. In May, Raath says they have four new ventures being developed, and by 2020, they want to have 24 live ventures with a monthly revenue of over $30,000.

"At Topl, we are really going to change the world," Raath tells the crowd. "But I can prove it to you." Read more about Topl here.

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Houston biotech company tests hard-to-fight cancer therapeutics

fighting cancer

A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.

Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

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This story originally appeared on our sister site, EnergyCapitalHTX.