Houston and Austin rideshare riders might soon walk away with some earnings — or at least some entertainment. Photo via playoctopus.com

Your next Lyft or Uber ride might win you some money. An interactive advertising and entertainment platform that works in rideshares has announced it will expand to the Houston and Austin markets — just in time for SXSW.

Maryland-based Play Octopus has already received thousands of applications from rideshare drivers wanting the device in their vehicles, according to a press release. And expanding to Houston was an obvious move.

"As the leading rideshare advertising company in the country, expanding into Texas' ride-sharing scene is a necessary first step as we expand outside of the Northeast. Austin and Houston are both tech-driven cities that rely on rideshare for convenient transportation," says Cherian Thomas, the co-founder and CEO of Play Octopus. "Digital video consumption and rideshare are both at all-time highs, and for brands, Octopus provides the ability to reach millions of rideshare passengers on a monthly basis."

The company has recently seen success from partnerships with the likes of Disney, Red Bull, Tiffany & Co., Sprint, National Geographic, and Weight Watchers in major Northeastern cities. Houston and Austin are just the start of Octopus' 2019 growth plans.

The way it works is the company provides free tablets to qualified drivers. Tablets come with a monthly data plan, a mount, the cables required, and up to $100 a month — not to mention the perks — like tips and ratings — that come with providing riders a new option for ride entertainment. On the other side of the table, advertisers have access to millions of monthly riders and can use branding and geo-targeting ads.

The company launched the platform on the East Coast about a year ago and is already in over 7,000 vehicles generating almost 10 million engagements a month. Currently, Octopus is in New York; Boston; Philadelphia; Washington, D.C.; Baltimore; and Richmond, Virginia.

"Our national expansion is being fueled by our brand and agency partners, and further solidifies the Octopus platform as a key component to media plans," says Dillon Tedesco, the chief revenue officer of Play Octopus. "As we surpass the 10,000,000 monthly engagement milestone and introduce exciting new ways to interact with our tablets, we're looking forward to providing our clients with a deeper impact in more cities across the country."

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Houston biotech company tests hard-to-fight cancer therapeutics

fighting cancer

A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.

Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

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This story originally appeared on our sister site, EnergyCapitalHTX.