The 22nd annual Rice Business Plan Competition named its winners across life science, clean energy, software, and more. Photo via Rice University/Twitter

Rice University brought back its international student startup competition to its in-person format in a big way, giving out nearly $2 million in investment plus thousands more in-kind prizes to over a dozen winning teams.

The 2022 Rice Business Plan Competition took place April 7-9 on campus, ending in a banquet and awards presentation at the Marriott Marquis on Saturday. Earlier this year, Rice announced the 42 student teams competing for the awards. The student competitors represent 31 universities — including three from European universities. The 42 teams were narrowed down from over 400 applicants and divided into five categories: energy, cleantech and sustainability; life sciences and health care solutions; consumer products and services; hard tech; and digital enterprise.

Over 250 judges, mentors, and investors were involved in the competition, naming seven finalists — each receiving thousands of dollars in investment funding.

Here were this year's finalists — and what they walked away with:

  • LIDROTEC from RWTH Aachen University, a cutting-edge machine that can better cut microchips for the semiconductor industry, is the big winner this year, taking home the $350,000 GOOSE Capital Investment Grand Prize. The team also won: the Softeq Venture Studio Prize ($50,000 cash, $75,000 in-kind), the TiE Houston Angels Investment Prize ($100,000), RBPC Alumnus, Thomas Healy, Investment Prize ($50,000), the Eagle Investors Prise ($5,000), Best Elevator Pitch - Hard Tech ($500), and RG Advisors CFO Consulting In-Kind Prize. The company also received a $6,700 in-kind prize from BakerBotts and an in-kind $25,000 from RG Advisory. The company's prize totaled over $682,200 in investment and in-kind awards.
  • The second place winner was Hoth Intelligence of University of Pittsburgh, an artificial intelligence platform for health care providers, securing a $100,000 investment prize. The company also won the Owl Investment Prize ($155,000), the HAN Investment Prize ($100,000), and the Pearland EDC Spirit of Entrepreneurship Prize ($25,000). The company also received a a $6,700 in-kind prize from BakerBotts. The company's prize totaled $386,700 in investment awards.
  • Invitris from the Technical University of Munich — a synthetic biology startup targeting antibiotic-resistant bacteria — won third place, which came with a $50,000 award. The team also won the nCourage Courageous Women Entrepreneur Investment Prize ($40,000), the Best Elevator Pitch - Life Science award ($500), and a $6,700 in-kind prize from BakerBotts. bringing its total earnings to $97,200.
  • Winning fourth place and a $5,000 prize was LymphaSense of Johns Hopkins, a medical device startup that's created a wearable lymphedema detection device for at-risk patients. The company also won the TMC Innovation Healthcare Investment Prize ($250,000 and entry into the TMC accelerator) and the Nixon Institute Prize ($3,000). The company's total winnings was $258,000.
  • INIA Biosciences from Boston University — a health tech startup that's created a bioelectric wearable device for kidney donor recipients — won fifth place and $5,000 in prize money.
  • The sixth place winner was Bold Move Beverages, a canned coffee cocktail company from the University of Texas at Austin, which won $5,000 for placing sixth and $10,000 from the RBPC Alumnus, Thomas Healy, Investment Prize. The company won a total of $15,000.
  • Lastly for the finalists, Anise Health of Harvard University, a digital health startups with an inclusive, data-driven platform for culturally-adapted mental health treatment, won seventh place and the $5,000 prize. The company also won first place in the wildcard round, which came with a $2,000 Edward H. Molter Memorial Prize. Anise walked away with $7,000 total.
Several companies won monetary prizes outside of the seven finalists. Here's what other student-founded companies in the competition won:
  • Mallard Bay Outdoors from Louisiana State University, an online marketplace for securely booking outdoor activities, won $216,500 in cash and in-kind prizes. The company won the Owl Investment Prize ($65,000), the Softeq Venture Studio Prize ($50,000 cash, $75,000 in-kind), the RBPC Alumnus, Thomas Healy, Investment Prize ($25,000), the Anbarci Family Company Showcase Prize ($1,000), and the Best Elevator Pitch - Consumer ($500).
  • TransCrypts from the University of Toronto and Harvard University, a secure blockchain platform for sharing employee documents, won two awards — the Owl Investment Prize ($50,000) and the Best Elevator Pitch - Digital ($500) — for a total of $50,500 in prizes.
  • Advanced Optronics of Carnegie Mellon University, a health tech company that develops smart sensors to improve patient outcomes, won two awards — the Pediatric Device Prize ($25,000) and the OFW Law FDA Regulatory Strategy In-Kind Prize — for a total of more than $25,000 in cash and in-kind prizes.
  • EpiSLS — a novel medical device startup that's automating in-vivo allergy testing — of the University of Michigan won the $25,000 Pediatric Device Prize.
  • Farm-to-closet women's apparel brand Pareto of Stanford University won the $10,000 nCourage Courageous Women Entrepreneur Investment Prize.
  • EpiFresh of Rice University, which developed a protective produce coating material that reduces food waste, won three awards for a total of $27,000. The company won the Energy, Cleantech & Sustainability Prize ($25,000), the Anbarci Family Company Showcase Prize ($1,000), and the Overall Best Elevator Pitch ($1,000).
  • Mantel of MIT, which is developing a high temperature liquid phase carbon capture material, won two awards for a total of $28,000 in prizes. The company won the New Climate Ventures Investment Prize ($25,000) and the DK Innovation Prize ($3,000).
  • Invictus BCI — a health tech startup building a noninvasive brain computer interface tools — from MIT won the the RBPC Alumni Network NABACO Prize for a total of $10,000 in winnings.
  • Health care fintech solution Woobie of Brigham Young University won the $25,000 Urban Capital Network Investment Prize.
  • KLAW Industries of Binghamton University, which has designed a way to recycle glass into concrete, won the Anbarci Family Company Showcase Prize ($1,000) and the Best Elevator Pitch - Energy ($500) prizes for a total of $1,500 in awards.
  • Acorn Genetics of Northwestern University, which is better optimizing genetic data for patients, won second place for the wildcard round, which came with the Edward H. Molter Memorial Prize ($1,750).
  • AI-powered stroke prevention platform PLAKK from McGill University won third place for the wildcard round, which came with the Edward H. Molter Memorial Prize ($1,500).
These startups join the ranks of 269 successful RBPC alumni companies — with 50 exits, five IPOs, and over $4.6 billion raised. RBPC was established in 2001.
The Rice Business Plan Competition is back in person this year, and these are the 42 teams that will go head to head for investments and prizes. Photo courtesy of Rice University

Rice University's student startup competition names 42 teams to compete for over $1 million in prizes

ready to pitch

The Rice Alliance for Technology and Entrepreneurship and the Jones Graduate School of Business have announced the 42 student teams that will compete in the 2022 Rice Business Plan Competition, which returns to an in-person format on the Rice University campus in April.

Of the teams competing for more than $1 million in prizes and funding in this year's competition, six hail from Texas — two teams each from Rice University, University of Texas at Austin, and Texas A&M University. The student competitors represent 31 universities — including three from European universities. The 42 teams were narrowed down from over 400 applicants and divided into five categories: energy, cleantech and sustainability; life sciences and health care solutions; consumer products and services; hard tech; and digital enterprise.

This is the first in-person RBPC since 2019, and the university is ready to bring together the entrepreneurs and a community of over 250 judges, mentors, and investors to the competition.

“As we come out on the other side of a long and challenging two years, we're feeling a sense of renewal and energy as we look to the future and finding inspiration from the next generation of entrepreneurs who are building a better world,” says Catherine Santamaria, director of the RBPC, in a news release.

“This year's competition celebrates student founders with a strong sense of determination — founders who are ready to adapt, build and grow companies that can change the future,” she continues. “We hope their participation will provide guidance and inspiration for our community.”

According to a news release, this year's RBPC Qualifier Competition, which narrowed down Rice's student teams that will compete in the official competition, saw the largest number of applicants, judges, and participants in the competition’s history. The Rice Alliance awarded a total of $5,000 in cash prizes to the top three teams from the internal qualifier: EpiFresh, Green Room and Anvil Diagnostics. From those three, Rice teams EpiFresh and Green Room received invitations to compete in the 2022 RBPC..

The full list of student teams that will be competing April 7 to 9 this year include:

  • Acorn Genetics from Northwestern University
  • Advanced Optronics from Carnegie Mellon University
  • Aethero Space from University of Missouri
  • AImirr from University of Chicago
  • AiroSolve from UCLA
  • Algeon Materials from UC San Diego
  • Anise Health from Harvard University
  • Beyond Silicon from Arizona State University
  • Bold Move Beverages from University of Texas at Austin
  • Diamante from University of Verona
  • EarthEn from Arizona State University
  • Empower Sleep from University of Pennsylvania
  • EpiFresh from Rice University
  • EpiSLS from University of Michigan
  • Green Room from Rice University
  • Horizon Health Solutions from University of Arkansas
  • Hoth Intelligence from Thomas Jefferson University
  • INIA Biosciences from Boston University
  • Invictus BCI from MIT
  • Invitris from Technical University of Munich (TUM)
  • KLAW Industries from Binghamton University
  • LIDROTEC from RWTH Aachen
  • Locus Lock from University of Texas at Austin
  • LymphaSense from Johns Hopkins University
  • Mallard Bay Outdoors from Louisiana State University
  • Mantel from MIT
  • Olera from Texas A&M University
  • OpenCell AI from Weill Cornell Medicine
  • OraFay from UCLA
  • Pareto from Stanford University
  • Photonect Interconnect Solutions from University of Rochester
  • PLAKK from McGill University
  • PneuTech from Johns Hopkins University
  • Rola from UC San Diego
  • RotorX from Georgia Tech
  • SimulatED from Carnegie Mellon University
  • SuChef from University of Pennsylvania
  • Symetric Finance from Fairfield University
  • Teale from Texas A&M University
  • Team Real Talk from University at Buffalo
  • TransCrypts from Harvard University
  • Woobie from Brigham Young University
Last year's awards had 54 student teams competing virtually, with over $1.4 million in cash and prizes awarded. Throughout RBPC's history, competitors have gone onto raise more than $3.57 billion in capital and more than 259 RBPC alumni have successfully launched their ventures. Forty RBPC startups that have had successful exits through acquisitions or trading on a public market, per the news release.
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CultureMap Emails are Awesome

Houston startup recognized for inclusivity on journey to commercialize next-gen therapeutics

future of medicine

A new Houston biotech company won a special award at the 16th Annual SXSW Pitch Award Ceremony earlier this month.

Phiogen, one of 45 companies that competed in nine categories, was the winner for best inclusivity, much to the surprise of the company’s CEO, Amanda Burkhardt.

Burkhardt tells InnovationMap that while she wanted to represent the heavily female patient population that Phiogen seeks to treat, really she just hires the most skilled scientists.

“The best talent was the folks that we have and it ends up being we have three green card holders on our team. As far as ethnicities, we have on our team we have Indian, African-American, Korean, Chinese Pakistani, Moroccan and Hispanic people and that just kind of just makes up the people who helped us on a day-to-day basis,” she explains.

Phiogen was selected out of 670 companies to be in the health and nutrition category at SXSW.

“We did really well, but there was another company that also did really well. And so we were not selected for the pitch competition, which we were a little bummed about because I killed the pitch,” Burkhardt recalls.

But Phiogen is worthy of note, pitch competition or not. The new company spun off from research at Dr. Anthony Maresso’s TAILOR Labs, a personalized phage therapy center at Baylor College of Medicine, last June.

“Our whole goal is to create the next generation of anti-infectives,” says Burkhardt.

That means that the company is making alternatives to antibiotics, but as Burkhardt says, “We’re hoping to be better than antibiotics.”

How does it work? Bacteriophages are viruses that infect bacteria.

“You can imagine them as the predators in the bacteria world, but they don't infect humans. They don't affect animals. They only infect bacteria,” Burkhardt explains.

Phiogen utilizes carefully honed bacteriophages to attack bacteria that include the baddies behind urinary tract infection (UTI), bacteremia (bacteria in the blood), and skin wounds.

The team’s primary focus is on treatment-resistant UTI. One example was a male patient who received Phiogen’s treatment thanks to an emergency-use authorization from the FDA. The gentleman had been suffering from an infection for 20 years. He was treated with Phiogen’s bacteriophage therapy for two weeks and completely cleared his infection with no recurrence.

Amanda Burkhardt is the CEO of Phiogen. Photo via LinkedIn

But Phiogen has its sights set well beyond the first maladies it’s treated. An oft-quoted 2016 report projected that by 2050, 10 million people a year will be dying from drug-resistant infections.

“A lot of scientists call it the silent pandemic because it's happening now, we're living in it, but there's just not as much being said about it because it normally happens to people who are already in the hospital for something else, or it's a comorbidity, but that's not always the case, especially when we're talking about urinary tract infections,” says Burkhardt.

Bacteriophages are important because they can be quickly trained to fight against resistant strains, whereas it takes years and millions of dollars to develop new antibiotics. There are 13 clinical trials that are currently taking place for bacteriophage therapy. Burkhardt estimates that the treatment method will likely gain FDA approval in the next five years.

“The FDA actually has been super flexible on progressing forward. Because they are naturally occurring, there's not really a safety risk with these products,” she says.

And Burkhardt, whose background is in life-science commercialization, says there’s no better place to build Phiogen than in Houston.

“You have Boston, you have the Bay [Area], and you have the Gulf Coast,” she says. “And Houston is cheaper, the people are friendlier, and it’s not a bad place to be in the winter.”

She also mentions the impressive shadow that Helix Park will cast over the ecosystem. Phiogen will move later this year to the new campus — one of the labs selected to join Baylor College of Medicine.

And as for that prize, chances are, it won’t be Phiogen’s last.

Houston student selected for prestigious health care research program

bright future

A Houston-area undergraduate student has been tapped for a prestigious national program that pairs early-career investigators with health research professionals.

Mielad Ziaee was selected for the National Institutes of Health’s 2023-2024 All of Us Research Scholar Program, which connects young innovators with experts "working to advance the field of precision medicine," according to a statement from UH. Ziaee – a 20-year-old majoring in psychology and minoring in biology, medicine and society who plans to graduate in 2025 — plans to research how genomics, or the studying of a person's DNA, can be used to impact health.

“I’ll be one of the ones that define what this field of personalized, precision medicine will look like in the future,” Ziaee said in a statement. “It’s exciting and it’s a big responsibility that will involve engaging diverse populations and stakeholders from different systems – from researchers to health care providers to policymakers.”

Ziaee aims to become a physician who can use an understanding of social health conditions to guide his clinical practice. At a young age, he was inspired to go into the field by his family's own experience.

According to UH, Ziaee is the oldest child of Iranian American immigrants. He saw firsthand the challenges of how language and cultural barriers can impact patients' access to and level of care.

“I think a lot of people define health as purely biological, but a lot of other factors influence our well-being, such as mental health, financial health, and even access to good food, medical care and the internet,” he said in a statement. “I am interested in seeing the relationship among all these things and how they impact our health. So far, a lot of health policies and systems have not really looked beyond biology.”

"I want everyone to have an equal chance to access health care and take charge of their well-being. We need to have the systems in place that let people do that,” he added.

Ziaee is already on his way to helping Houston-based and national health systems and organizations make headway in this area.

He was named as a student regent on the UH System Board of Regents last year, sits on the board of the Houston chapter of the American Red Cross, and is an Albert Schweitzer Fellow.

Last year he was a Centers for Disease Control and Prevention John R. Lewis scholar, for which he presented his research project about predicting food insecurity in pediatric clinical settings and recommendations to improve the assessment based off his summer research with the Johns Hopkins University School of Medicine and the Kennedy Krieger Institute.

Prior to this, he completed a 10-week guided research experience using data visualization and predictive modeling techniques to assess food insecurity in the Third Ward.

“I just took every opportunity that came to me,” Ziaee said. “All my experiences connect with my central desire to increase health access and improve health care. I am very intentional about connecting the dots to my passion.”

Earlier this year, three UH student researchers were named among 16 other early-stage research projects at U.S. colleges and universities to receive a total of $17.4 million from the DOE's Office of Fossil Energy and Carbon Management (FECM). The projects were each awarded between about $750,000 to up to $1.5 million.

Houston tech entrepreneur expands energy data co. in Europe, continues to scale

houston innovators podcast episode 229

The technology that Amperon provides its customers — a comprehensive, AI-backed data analytics platform — is majorly key to the energy industry and the transition of the sector. But CEO Sean Kelly says he doesn't run his business like an energy company.

Kelly explains on the Houston Innovators Podcast that he chooses to run Amperon as a tech company when it comes to hiring and scaling.

"There are a lot of energy companies that do tech — they'll hire a large IT department, they'll outsource a bunch of things, and they'll try to undergo a product themselves because they think it should be IP," he says on the show. "A tech company means that at your core, you're trying to build the best and brightest technology."

To Kelly, Amperon should be hiring in the same field as Google and other big tech companies that sit at the top of the market. And Kelly has done a lot of hiring recently. Recently closing the company's $20 million series B round last fall led by Energize Capital, Amperon has tripled its team in the past 14 months.

With his growing team, Kelly also speaks to the importance of partnerships as the company scales. Earlier this month, Amperon announced that it is replatforming its AI-powered energy analytics technology onto Microsoft Azure. The partnership with the tech giant allows Amperon's energy sector clients to use Microsoft's analytics stack with Amperon data.

And there are more collaborations where that comes from.

"For Amperon, 2024 is the year of partnerships," Kelly says on the podcast. "I think you'll see partnership announcements here in the next couple of quarters."

Along with more partners, Amperon is entering an era of expansion, specifically in Europe, which Kelly says has taken place at a fast pace.

"Amperon will be live in a month in 25 countries," he says.

While Amperon's technology isn't energy transition specific, Kelly shares how it's been surprising how many clean tech and climate tech lists Amperon has made it on.

"We don't brand ourselves as a clean tech company," Kelly says, "but we have four of the top six or eight wind providers who have all invested in Amperon. So, there's something there."

Amperon, which originally founded in 2018 before relocating to Houston a couple of years ago, is providing technology that helps customers move toward a lower carbon future.

"If you look at our customer base, Amperon is the heart of the energy transition. And Houston is the heart of the energy transition," he says.