These are the Houston companies headed to MassChallenge Texas in Austin

Texas road trip

A handful of Houston startups will be bouncing back and forth to Austin for the second annual MassChallenge Texas accelerator. Getty Images

It's the second cohort for Boston-based MassChallenge Texas in Austin, and this year's 74 selected finalists are well represented by Houston.

"Coming from an extremely competitive application pool, the startups in our second Austin-based cohort represent an incredibly high bar of creativity and talent, all of who are poised to make an impact," says Mike Millard, managing director of MassChallenge Texas, in a release. "This year's program will offer the finalists innovation at scale with direct access to resources through our programs in Houston and Austin, and our community around the state. Through these channels, startups will have more opportunities to test and validate their ideas with partners while creating meaningful engagements to help them get to pilot or pivot as fast as possible."

While there is the upcoming MassChallenge Texas inaugural Houston cohort, these seven companies opted for a spot in the Austin-based cohort where the stakes are higher and cash prizes are on the line — $500,000, the largest equity-free cash prize in Texas, to be precise. (Houston's inaugural set of prizes reportedly don't included money.)

These are seven of the Houston-related companies that will be trekking back and forth to Austin from June until October.

crewcollar

Getty Images

It's crewcollar's mission to optimize hiring for industrial and blue-collar jobs, simplifying the entire process from curated job posts to paperwork filing. The company is based just outside of Houston in Missouri City.

"We are super excited to be joining MassChallenge Texas, and know that this experience will help us take it to the next level," says M. Siler, CEO and founder, in a release.

GotSpot Inc.

Courtesy of GotSpot

Houston-based GotSpot is Reda Hicks solution to finding temporary space quickly and easily — in a way that benefits all sides of the transaction. The model is like AirBnb, but for retail, meeting, and even emergency space. The corporate lawyer has grown the platform over the past few years and the MassChallenge opportunity is another move in the right direction. Click here to read more about Hicks and GotSpot.

Grant Source

Photo via grantsourceapp.com

Grant Source is like the magic genie to help organizations find funding through grants and opportunities. The Houston startup has a database of opportunities and can help match businesses with appropriate grants to apply to — all within the Grant Source mobile app.

Guzo

Getty Images

Guzo is the tool every traveler has dreamed up. The Houston-based app connects travelers — not just in the planning phase — but throughout the travel process. The company was created by two brothers — Joshua and Gordon Taylor — and is the recreation of Croozen, formerly a long-distance carpool app.

"One of the things that got Gordan and I excited in the beginning of Croozen was just the idea of someone else in the car with you and that shared experience," Joshua Taylor tells InnovationMap in a previous interview about revamping Croozen as Guzo. "Looking past that, just being focused on the car was hindering us. Let's divorce the car and focus on travel as a whole."

Lazarus 3D

Photo via laz3d.com

Practice makes perfect, and surgeons should be as close to perfect as possible, right? Lazarus 3D uses 3D printing to make realistic body parts and organs so that surgeons can rehearse their surgeries before ever slicing into a patient. The company is conveniently located in the Texas Medical Center.

Pilot Plus

Photo via pilotplus.com

The trucking industry needs a rebrand. It's a tireless job that's go-go-go, and the unappealing nature of the career isn't ideal. Pilot Plus puts the humanity back in the process that benefits the driver and makes for bragging rights for the company employing the trucker. The logistics company allows for a system of drivers that work together for the long haul so that drivers can actually spend time resting in their own homes.

Topl

Courtesy of Topl

Topl's MassChallenge bio lists their HQ in the Netherlands, but the blockchain startup founded by three Rice University alumni has some of its operations right here in town. Topl has a goal of using blockchain technology to connect the dots and enhance transparency in various applications from retail to even being able to track the success of investments or scholarships.

"We are a generation that wants a story," Kim Raath, president at Topl, tells InnovationMap in a previous interview. "We want an origin, and don't want to be fooled. And, because you might be able to reduce the cost by having this transparency, you might be able to bring down the cost on both sides."


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Houston's Ion District to expand with new research and tech space, The Arc

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Houston's Ion District is set to expand with the addition of a nearly 200,000-square-foot research and technology facility, The Arc at the Ion District.

Rice Real Estate Company and Lincoln Property Company are expected to break ground on the state-of-the-art facility in Q2 2026 with a completion target set for Q1 2028, according to a news release.

Rice University, the new facility's lead tenant, will occupy almost 30,000 square feet of office and lab space in The Arc, which will share a plaza with the Ion and is intended to "extend the district’s success as a hub for innovative ideas and collaboration." Rice research at The Arc will focus on energy, artificial intelligence, data science, robotics and computational engineering, according to the release.

“The Arc will offer Rice the opportunity to deepen its commitment to fostering world-changing innovation by bringing our leading minds and breakthrough discoveries into direct engagement with Houston’s thriving entrepreneurial ecosystem,” Rice President Reginald DesRoches said in the release. “Working side by side with industry experts and actual end users at the Ion District uniquely positions our faculty and students to form partnerships and collaborations that might not be possible elsewhere.”

Developers of the project are targeting LEED Gold certification by incorporating smart building automation and energy-saving features into The Arc's design. Tenants will have the opportunity to lease flexible floor plans ranging from 28,000 to 31,000 square feet with 15-foot-high ceilings. The property will also feature a gym, an amenity lounge, conference and meeting spaces, outdoor plazas, underground parking and on-site retail and dining.

Preleasing has begun for organizations interested in joining Rice in the building.

“The Arc at the Ion District will be more than a building—it will be a catalyst for the partnerships, innovations and discoveries that will define Houston’s future in science and technology,” Ken Jett, president of Rice Real Estate Company, added in the release. “By expanding our urban innovation ecosystem, The Arc will attract leading organizations and talent to Houston, further strengthening our city’s position as a hub for scientific and entrepreneurial progress.”

Intel Corp. and Rice University sign research access agreement

innovation access

Rice University’s Office of Technology Transfer has signed a subscription agreement with California-based Intel Corp., giving the global company access to Rice’s research portfolio and the opportunity to license select patented innovations.

“By partnering with Intel, we are creating opportunities for our research to make a tangible impact in the technology sector,” Patricia Stepp, assistant vice president for technology transfer, said in a news release.

Intel will pay Rice an annual subscription fee to secure the option to evaluate specified Rice-patented technologies, according to the agreement. If Intel chooses to exercise its option rights, it can obtain a license for each selected technology at a fee.

Rice has been a hub for innovation and technology with initiatives like the Rice Biotech Launch Pad, an accelerator focused on expediting the translation of the university’s health and medical technology; RBL LLC, a biotech venture studio in the Texas Medical Center’s Helix Park dedicated to commercializing lifesaving medical technologies from the Launch Pad; and Rice Nexus, an AI-focused "innovation factory" at the Ion.

The university has also inked partnerships with other tech giants in recent months. Rice's OpenStax, a provider of affordable instructional technologies and one of the world’s largest publishers of open educational resources, partnered with Microsoft this summer. Google Public Sector has also teamed up with Rice to launch the Rice AI Venture Accelerator, or RAVA.

“This agreement exemplifies Rice University’s dedication to fostering innovation and accelerating the commercialization of groundbreaking research,” Stepp added in the news release.

Houston team develops low-cost device to treat infants with life-threatening birth defect

infant innovation

A team of engineers and pediatric surgeons led by Rice University’s Rice360 Institute for Global Health Technologies has developed a cost-effective treatment for infants born with gastroschisis, a congenital condition in which intestines and other organs are developed outside of the body.

The condition can be life-threatening in economically disadvantaged regions without access to equipment.

The Rice-developed device, known as SimpleSilo, is “simple, low-cost and locally manufacturable,” according to the university. It consists of a saline bag, oxygen tubing and a commercially available heat sealer, while mimicking the function of commercial silo bags, which are used in high-income countries to protect exposed organs and gently return them into the abdominal cavity gradually.

Generally, a single-use bag can cost between $200 and $300. The alternatives that exist lack structure and require surgical sewing. This is where the SimpleSilo comes in.

“We focused on keeping the design as simple and functional as possible, while still being affordable,” Vanshika Jhonsa said in a news release. “Our hope is that health care providers around the world can adapt the SimpleSilo to their local supplies and specific needs.”

The study was published in the Journal of Pediatric Surgery, and Jhonsa, its first author, also won the 2023 American Pediatric Surgical Association Innovation Award for the project. She is a recent Rice alumna and is currently a medical student at UTHealth Houston.

Bindi Naik-Mathuria, a pediatric surgeon at UTMB Health, served as the corresponding author of the study. Rice undergraduates Shreya Jindal and Shriya Shah, along with Mary Seifu Tirfie, a current Rice360 Global Health Fellow, also worked on the project.

In laboratory tests, the device demonstrated a fluid leakage rate of just 0.02 milliliters per hour, which is comparable to commercial silo bags, and it withstood repeated disinfection while maintaining its structure. In a simulated in vitro test using cow intestines and a mock abdominal wall, SimpleSilo achieved a 50 percent reduction of the intestines into the simulated cavity over three days, also matching the performance of commercial silo bags. The team plans to conduct a formal clinical trial in East Africa.

“Gastroschisis has one of the biggest survival gaps from high-resource settings to low-resource settings, but it doesn’t have to be this way,” Meaghan Bond, lecturer and senior design engineer at Rice360, added in the news release. “We believe the SimpleSilo can help close the survival gap by making treatment accessible and affordable, even in resource-limited settings.”
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