A handful of Houston startups will be bouncing back and forth to Austin for the second annual MassChallenge Texas accelerator. Getty Images

It's the second cohort for Boston-based MassChallenge Texas in Austin, and this year's 74 selected finalists are well represented by Houston.

"Coming from an extremely competitive application pool, the startups in our second Austin-based cohort represent an incredibly high bar of creativity and talent, all of who are poised to make an impact," says Mike Millard, managing director of MassChallenge Texas, in a release. "This year's program will offer the finalists innovation at scale with direct access to resources through our programs in Houston and Austin, and our community around the state. Through these channels, startups will have more opportunities to test and validate their ideas with partners while creating meaningful engagements to help them get to pilot or pivot as fast as possible."

While there is the upcoming MassChallenge Texas inaugural Houston cohort, these seven companies opted for a spot in the Austin-based cohort where the stakes are higher and cash prizes are on the line — $500,000, the largest equity-free cash prize in Texas, to be precise. (Houston's inaugural set of prizes reportedly don't included money.)

These are seven of the Houston-related companies that will be trekking back and forth to Austin from June until October.

crewcollar

Getty Images

It's crewcollar's mission to optimize hiring for industrial and blue-collar jobs, simplifying the entire process from curated job posts to paperwork filing. The company is based just outside of Houston in Missouri City.

"We are super excited to be joining MassChallenge Texas, and know that this experience will help us take it to the next level," says M. Siler, CEO and founder, in a release.

GotSpot Inc.

Courtesy of GotSpot

Houston-based GotSpot is Reda Hicks solution to finding temporary space quickly and easily — in a way that benefits all sides of the transaction. The model is like AirBnb, but for retail, meeting, and even emergency space. The corporate lawyer has grown the platform over the past few years and the MassChallenge opportunity is another move in the right direction. Click here to read more about Hicks and GotSpot.

Grant Source

Photo via grantsourceapp.com

Grant Source is like the magic genie to help organizations find funding through grants and opportunities. The Houston startup has a database of opportunities and can help match businesses with appropriate grants to apply to — all within the Grant Source mobile app.

Guzo

Getty Images

Guzo is the tool every traveler has dreamed up. The Houston-based app connects travelers — not just in the planning phase — but throughout the travel process. The company was created by two brothers — Joshua and Gordon Taylor — and is the recreation of Croozen, formerly a long-distance carpool app.

"One of the things that got Gordan and I excited in the beginning of Croozen was just the idea of someone else in the car with you and that shared experience," Joshua Taylor tells InnovationMap in a previous interview about revamping Croozen as Guzo. "Looking past that, just being focused on the car was hindering us. Let's divorce the car and focus on travel as a whole."

Lazarus 3D

Photo via laz3d.com

Practice makes perfect, and surgeons should be as close to perfect as possible, right? Lazarus 3D uses 3D printing to make realistic body parts and organs so that surgeons can rehearse their surgeries before ever slicing into a patient. The company is conveniently located in the Texas Medical Center.

Pilot Plus

Photo via pilotplus.com

The trucking industry needs a rebrand. It's a tireless job that's go-go-go, and the unappealing nature of the career isn't ideal. Pilot Plus puts the humanity back in the process that benefits the driver and makes for bragging rights for the company employing the trucker. The logistics company allows for a system of drivers that work together for the long haul so that drivers can actually spend time resting in their own homes.

Topl

Courtesy of Topl

Topl's MassChallenge bio lists their HQ in the Netherlands, but the blockchain startup founded by three Rice University alumni has some of its operations right here in town. Topl has a goal of using blockchain technology to connect the dots and enhance transparency in various applications from retail to even being able to track the success of investments or scholarships.

"We are a generation that wants a story," Kim Raath, president at Topl, tells InnovationMap in a previous interview. "We want an origin, and don't want to be fooled. And, because you might be able to reduce the cost by having this transparency, you might be able to bring down the cost on both sides."


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Texas universities develop innovative open-source platform for cell analysis

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What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe.

That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston.

SPACe, or Swift Phenotypic Analysis of Cells, was created to be used on standard computers that even small labs can access, meaning cellular analysis using images produced through cell painting has a lower barrier to entry than ever before.

“The pharmaceutical industry has been accustomed to simplifying complex data into single metrics. This platform allows us to shift away from that approach and instead capture the full diversity of cellular responses, providing richer, more informative data that can reveal new avenues for drug development,” Michael Mancini, professor of molecular and cellular biology and director of the Gulf Coast Consortium Center for Advanced Microscopy and Image Informatics co-located at Baylor College of Medicine and TAMU Institute for Bioscience and Technology.

SPACe is not only accessible because of its less substantial computational needs. Because the platform is open-source, it’s available to anyone who needs it. And it can be used by academic and pharmaceutical researchers alike.

“The platform allows for the identification of non-toxic effects of drugs, such as alterations in cell shape or effects on specific organelles, which are often overlooked by traditional assays that focus largely on cell viability,” says Fabio Stossi, currently a senior scientist with St. Jude Children’s Research Hospital, the lead author who was at Baylor during the development of SPACe.

The platform is a better means than ever of analyzing thousands of individual cells through automated imaging platforms, thereby better capturing the variability of biological processes. Through that, SPACe allows scientists an enhanced understanding of the interactions between drugs and cells, and does it on standard computers, translating to scientists performing large-scale drug screenings with greater ease.

"This tool could be a game-changer in how we understand cellular biology and discover new drugs. By capturing the full complexity of cellular responses, we are opening new doors for drug discovery that go beyond toxicity,” says Stossi.

And the fact that it’s open-source allows scientists to access SPACe for free right now. Researchers interested in using the platform can access it through Github at github.com/dlabate/SPACe. This early version could already make waves in research, but the team also plans to continually improve their product with the help of collaborations with other institutions.

The Ion names new coworking partner for Houston innovation hub

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Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role.

The Ion, owned by Rice Real Estate and located at 4201 Main St., is a 266,000-square-foot office building and innovation hub in the 16-acre Ion District.

Features of the coworking space include private suites and offices, dedicated desks, phone booths and conference rooms. In 2022, Common Desk said it was expanding the space by 28,000 square feet, bringing it to the current size.

“(Industrious’) unparalleled expertise in delivering quality, hospitality-driven workspaces complements our vision of creating a world-class ecosystem where entrepreneurs, corporations, and academia converge to drive innovation forward,” Ken Jett, president of Rice Real Estate, said in a statement.

Natalie Levine, senior manager of real estate at Industrious, says her company will work with Rice Real Estate “to continue to position the Ion as an invaluable contributor to the growth of Houston’s innovation community.”

Dallas-based commercial real estate services company CBRE said Jan. 14 that it had agreed to acquire Industrious in a deal valued at $400 million.

The Ion is Industrious’ second location in Houston. The company’s other local coworking space is at 1301 McKinney St.

Office tenants at the Ion include Occidental Petroleum, Fathom Fund, Activate, Carbon Clean, Microsoft and Chevron Technology Ventures.