NASA doled out funding to 12 startups — and one from Houston makes the cut. Photo courtesy of re:3D

Houston-based re:3D Inc was recently one of 12 innovative companies from around the country to be granted Phase II awards from a NASA small business initiative, the space giant announced earlier this week.

The grants of up to $850,000 are awarded to early-stage, high-risk technology concepts that could be commercialized for use in space and on Earth as part of NASA's SBIR Ignite pilot, which is part of NASA’s Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs.

The program was launched to support emerging companies "whose end customers may not be only NASA but are still creating technology that NASA cares about,” Jason L. Kessler, program executive for the NASA SBIR/STTR program, says in a previous statement. And it aims to attract companies that have not yet worked with NASA.

The concepts from the cohort have applications in climate resilience, low-cost solar cells and active debris remediation. Re:3D Inc.'s project looks to develop a recycling system that uses a 3D printer to turn thermoplastic waste generated in orbit into functional and useful objects, according to the project's proposal.

SBIR Ignite made its inaugural Phase I awards in 2022, granting about $2 million in total to the 12 companies, including re:3D Inc. The Phase II grants are intended to help the companies create their prototypes.

“We are proud that all 12 of the small businesses are continuing with our program and persevering through the tough realities of early-stage research and development,” Kessler said in a statement made this month. "These awards foster a unique range of technologies that we hope will have positive impacts on the lives of everyday Americans in the future."

Re3D Inc. is the only company from Texas in the cohort. The other 11 awarded companies and their projects include:

  • Ampaire Inc.: High Efficiency Powertrain for Hybrid Aircraft
  • Canopy Aerospace Inc.: Reusable Heatshields through Additive Manufacturing
  • Cecilia Energy: Catalytic Conversion of Waste Plastic to Hydrogen
  • Crystal Sonic Inc.: Reducing Cost of Space Photovoltaics via Sound-Assisted Substrate Reuse
  • H3X Technologies Inc.: HPDM-30 – A 10 kW/kg Integrated Motor Drive for UAV and Aircraft Electric Propulsion
  • Outpost Technologies Corporation: Outpost Cargo Ferry: A Rapid Cargo Downmass Vehicle
  • Solestial, Inc.: Next Generation Silicon Based Solar Arrays for Space Stations and Other Permanent Space Infrastructure
  • StormImpact Inc.: Optimizing vegetation management to improve the resilience of the electrical power system to extreme weather
  • Terrafuse, Inc.: Wildfire Mitigation through Explainable Risk Predictions
  • Trans Astronautica Corporation: Mini Bee Capture Bag for Active Debris Remediation
  • Turion Space Corp.: Low-Cost CubeSat for Active Removal of Sizable Space Debris Utilizing a Mothership Architecture

Re:3D Inc. was founded in 2013 by NASA contractors Samantha Snabes and Matthew Fiedler and is based in Clear Lake. It's known for its GigaBot 3D printer, which uses recycled materials to create larger devices.

Since its founding it's been named to numerous accelerators and has earned national recognition, like the Tibbetts Award from the U.S. Small Business Administration, which honors small businesses that are at the forefront of technology. It was selected by the SBA to participate in its inaugural America’s Seed Fund Startup Expo last year.

Co-founder Snabes spoke on the Houston Innovators Podcast in 2020. Click here to listen to the full, in-depth interview.

Houston-area Ad Astra Rocket Company, which is working on a technology that could increase the speed of space travel, received fresh funding from NASA. Photo via NASA.gov

NASA doles out $98M in funding to small business innovators, including 6 Texas firms

grants lifting off

Almost 100 small businesses with aerospace technology received the greenlight from NASA on their proposals for grant funding.

NASA approved 112 proposals from 92 small businesses in April. These businesses will receive a slice of the $98 million Phase II funding from the Small Business Innovation Research program. The early-stage $850,000 SBIR grants allow awardees to build on their success from the program's first phase. The firms will have 24 months to execute on their proposals with the fresh funding.

“These Phase II awards support a breadth of technologies that have the potential to be transformational for so many different projects and missions across NASA,” says Jenn Gustetic, director of early stage innovation and partnerships for NASA's Space Technology Mission Directorate, in a news release. “In addition, it’s important that we’re including the innovative potential of all of America’s small businesses and entrepreneurs, so we’re proud that 28% of these awards are to underrepresented small businesses and 31% are to first time SBIR Phase II awardees."

Six of the award recipients are based in Texas. Here are the companies and their proposal technology:

  • Ad Astra Rocket Company, headquartered in Webster: Improved Thermo-Mechanical Design of the VASIMR RF Coupler
  • Lunar Resources Inc., headquartered in Houston: Ultra-Electrical-Efficient Process to Perform Regolith Additive Manufacturing of Complex Structures
  • Lynntech Inc., headquartered in College Station: Miniaturized Reagent Regenerative Ion Analyzer for Elemental Analysis
  • QED Secure Solutions, headquartered in Coppell: Avionics Intrusion Detection and Attack Identification
  • Stone Aerospace Inc., headquartered in Del Valle: Sediment Sequestration for Hot Water Drilling Cryobots
  • Texas Research Institute Austin Inc., headquartered in Austin: Accelerated Creep Test Methodologies for Space Habitat Softgood Structural Materials

The Ad Astra Rocket Company's technology, the Variable Specific Impulse Magnetoplasma Rocket, or VASIMR, is an electrothermal thruster that, once developed using the grant, would allow for faster space travel.

“Our program has the responsibility of supporting ideas and technologies that will have impact on NASA’s work and have strong commercial potential,” says Jason L. Kessler, program executive for NASA's SBIR and Small Business Technology Transfer program, in the release. “We're always excited when we can find technologies that help our agency's missions while also having direct benefits for all."

NASA's SBIR program, which takes no equity, offers up to $1 million to selected business during the first three years. Post Phase II opportunities include up to nearly $3 million in funding. The program is a part of NASA's Space Technology Mission Directorate and managed by NASA’s Ames Research Center in California's Silicon Valley.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”