New initiative to bring protective equipment to underserved parts of Houston

PPE for the people

PPE For The People will donate personal protective equipment to workers in communities disproportionately affected by COVID-19. Photos via houston.impacthub.net/ppeforthepeople

Through a collaboration between a 3D printing company and a nonprofit organization, small businesses in underserved parts of town are able to apply to receive personal protective equipment donations.

Impact Hub Houston and re:3D have teamed up for an initiative called PPE For The People that will create and donate PPE to small businesses disproportionately affected by the coronavirus outbreak.

"All of the emerging data indicates that, while a coronavirus may not discriminate, disparities that already exist in society are putting communities of color at a disproportionately higher risk of infection, serious illness, and death from COVID-19," says Grace Rodriguez, CEO and executive director of Impact Hub Houston.

According to a news release, the initiative will support workers across industries — from restaurants employees and bus and delivery drivers to small businesses that seek to reopen safely, like barbershops and nail salons.

Impact Hub Houston works to prioritize inclusion in Houston, which has been recognized as the most diverse city in the nation.

"There a number of societal factors that are leading to disproportionately higher COVID-19 cases and deaths among minority communities," says Rodriguez, specifying that these factors include lack of access to health care, overrepresentation of people of color in jobs considered essential, and more.

To start, the initiative has identified the southeast, south, and southwest parts of Houston to deliver four types of 3D-printed PPE: face shields, ear savers, hands-free door opener, and splash guards.

"re:3D has extensively researched PPE production for COVID-19 throughout the crisis as well as collaborated with healthcare workers, first responders, and local businesses to identify where there are gaps in their ability to protect themselves and their customers," says re:3D's community liaison, Charlotte Craff. "We have started with these items because we are confident they fill those needs."

The campaign, which is raising money and seeking volunteers online, began Wednesday, May 6, and expects to deliver its first PPE next week. The organizations are looking into expanding the PPE offered, as well as their reach, but it depends on fundraising.

"We would like to expand the project to serve communities in the northeast and other high-risk areas of Houston, but that all depends on how much funding we can raise to keep producing and delivering PPE," Rodriguez explains.

According to the release, Impact Hub Houston is financially supporting the initiative through its Fiscal Sponsorship Program, which re:3D applied to. The H-Force network, a crisis collaboration, is also lending its support to this initiative.

"We are honored to help those who are most vulnerable," says Craff in the release. "Data from the CDC has shown minority communities are at greater risk of critical illness from COVID-19, and we want to help local small businesses protect their employees as best as possible without it being an added financial burden on already strained industries."

Boeing has started making plastic face shields at its San Antonio factory. Photo courtesy of Boeing

Aerospace giant taps Texas site to make face shields for health care workers battling the coronavirus

in need of PPE

Chicago-based Boeing, which is a major employer in Texas, began producing face shields for front-line healthcare workers at several of its facilities across the country. The company's San Antonio location is among the sites selected.

On April 10, Boeing delivered its first 2,300 face shields to the Kay Bailey Hutchison Convention Center in Dallas, which is an alternate treatment site for COVID-19 patients. The U.S. Department of Health and Human Services accepted the shipment.

In collaboration with the Federal Emergency Management Agency, Boeing is donating face shields to health care providers around the country. The company plans to make thousands of these face shields each week in San Antonio; St. Louis; Southern California; the Seattle area; Mesa, Arizona; Huntsville, Alabama; Philadelphia; Charleston, South Carolina; Salt Lake City; and Portland, Oregon.

"Boeing is proud to stand alongside many other great American companies in the fight against COVID-19, and we are dedicated to supporting our local communities, especially our front-line health care professionals, during this unprecedented time," David Calhoun, president and CEO of Boeing, says in a release.

At Port San Antonio, Boeing operates one of the world's largest military aircraft maintenance, repair, and overhaul facilities. In August 2019, Boeing said it was adding 500 jobs in San Antonio, on top of the 900 people already employed there.

Solvay, a longtime Boeing supplier, has provided clear film for the face shields. Another supplier, Trelleborg Sealing Solutions, has donated elastic for the adjustable headbands.

To date, Boeing says it has donated tens of thousands of pieces of personal protective equipment — including face masks, goggles, gloves, safety glasses, and protective bodysuits — to support U.S. health care workers fighting the pandemic.

"History has proven that Boeing is a company that rises to the toughest challenges with people who are second to none," Calhoun adds. "Today, we continue that tradition, and we stand ready to assist the federal government's response to this global pandemic."

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This article originally ran on CultureMap.

A startup and a nonprofit makerspace have rallied to create PPE, or personal protective equipment, for local hospitals. Getty Images

Houston tech community answers the call for medical equipment amid coronavirus-caused shortages

in need of PPE

In the span of one day, the founders of Houston-based Lazarus 3D received calls from emergency room directors and physicians and vice presidents of hospitals explaining a dire need for personal protective equipment — like surgical masks and face shields — for medical professionals in the front lines of the battle against COVID-19.

"We stopped everything we were doing," says Jacques Zaneveld, co-founder of Lazarus, which makes 3D-printed human organs for surgeons to practice on. "We've moved 100 percent of our focus on developing PPE."

Now, Zaneveld with his co-founder, Smriti Agrawal Zaneveld, have manufacturing orders in for 700,000 surgical masks weekly and have designed a non-FDA approved face shield, which they have ordered a few million of. The duo has taken out a short-term loan to front the cost of the medical equipment and are now looking for the right customers to buy these new PPE products. All hospitals and medical professionals in need of supplies can head to Lazarus' website to request more info.

"Our personal feeling has been to do whatever we can do to build as many as possible," Jacques tells InnovationMap. "It's very stressful because I'm borrowing money that we don't have in order to set up these production lines."

On the other side of town, 3D printing nonprofit TXRX has reprogramed 30 of its 3D printers to make PPE. The nonprofit is working Memorial Hermann to quickly prototype and test items made with materials they can get their hands on.

The Center for Disease Control has relaxed some of the requirements for PPE in light of the crisis and shortage, and Roland von Kurnatowski, president at TX/RX Labs, says that has helped speed up their efforts. But, the biggest challenge, he says, has been to quickly get together a design and prototype for Memorial Hermann to give them feedback so that they can then produce the products.

"I think there are a lot of people out there producing devices, but I think the problem is there's not a lot of clarity around materials, quality, and acceptance. People are doing what they can with what they've got," says von Kurnatowski. "Our hope working with Memorial Hermann was to make sure we are devising and testing devices that are functional and appropriate.

TXRX is also relying on Memorial Hermann and others in the medical community to indicate which PPE devices are most needed. Currently, the nonprofit is printing 10,000 face shields for Memorial Hermann, but also has designs for N95 respirators, surgical masks, a positive air pressure respirator (or PAPR), Tyvek suit, and even a portable shield for the intubation process.

Von Kurnatowski says the Houston community can get involved by donating to TXRX's GoFundMe campaign. The 3D printing process is quick and local, but expensive and out of budget for hospitals, so TXRX is taking a loss on its products it is creating. The organization is also looking for people who might have 3D printing materials or experience to volunteer — TXRX has about 20 people working on this but hopes that number ramps up to 60 to 80 people helping out.

Crisis also brings the community together in their time of need — that's what Zaneveld says he sees happening.

"Everyone who is at all involved in the medical space in engineering in Houston is trying to put stuff out," Zaneveld says. "We're sharing information and trying to work together to support each other."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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