New initiative to bring protective equipment to underserved parts of Houston

PPE for the people

PPE For The People will donate personal protective equipment to workers in communities disproportionately affected by COVID-19. Photos via houston.impacthub.net/ppeforthepeople

Through a collaboration between a 3D printing company and a nonprofit organization, small businesses in underserved parts of town are able to apply to receive personal protective equipment donations.

Impact Hub Houston and re:3D have teamed up for an initiative called PPE For The People that will create and donate PPE to small businesses disproportionately affected by the coronavirus outbreak.

"All of the emerging data indicates that, while a coronavirus may not discriminate, disparities that already exist in society are putting communities of color at a disproportionately higher risk of infection, serious illness, and death from COVID-19," says Grace Rodriguez, CEO and executive director of Impact Hub Houston.

According to a news release, the initiative will support workers across industries — from restaurants employees and bus and delivery drivers to small businesses that seek to reopen safely, like barbershops and nail salons.

Impact Hub Houston works to prioritize inclusion in Houston, which has been recognized as the most diverse city in the nation.

"There a number of societal factors that are leading to disproportionately higher COVID-19 cases and deaths among minority communities," says Rodriguez, specifying that these factors include lack of access to health care, overrepresentation of people of color in jobs considered essential, and more.

To start, the initiative has identified the southeast, south, and southwest parts of Houston to deliver four types of 3D-printed PPE: face shields, ear savers, hands-free door opener, and splash guards.

"re:3D has extensively researched PPE production for COVID-19 throughout the crisis as well as collaborated with healthcare workers, first responders, and local businesses to identify where there are gaps in their ability to protect themselves and their customers," says re:3D's community liaison, Charlotte Craff. "We have started with these items because we are confident they fill those needs."

The campaign, which is raising money and seeking volunteers online, began Wednesday, May 6, and expects to deliver its first PPE next week. The organizations are looking into expanding the PPE offered, as well as their reach, but it depends on fundraising.

"We would like to expand the project to serve communities in the northeast and other high-risk areas of Houston, but that all depends on how much funding we can raise to keep producing and delivering PPE," Rodriguez explains.

According to the release, Impact Hub Houston is financially supporting the initiative through its Fiscal Sponsorship Program, which re:3D applied to. The H-Force network, a crisis collaboration, is also lending its support to this initiative.

"We are honored to help those who are most vulnerable," says Craff in the release. "Data from the CDC has shown minority communities are at greater risk of critical illness from COVID-19, and we want to help local small businesses protect their employees as best as possible without it being an added financial burden on already strained industries."

Boeing has started making plastic face shields at its San Antonio factory. Photo courtesy of Boeing

Aerospace giant taps Texas site to make face shields for health care workers battling the coronavirus

in need of PPE

Chicago-based Boeing, which is a major employer in Texas, began producing face shields for front-line healthcare workers at several of its facilities across the country. The company's San Antonio location is among the sites selected.

On April 10, Boeing delivered its first 2,300 face shields to the Kay Bailey Hutchison Convention Center in Dallas, which is an alternate treatment site for COVID-19 patients. The U.S. Department of Health and Human Services accepted the shipment.

In collaboration with the Federal Emergency Management Agency, Boeing is donating face shields to health care providers around the country. The company plans to make thousands of these face shields each week in San Antonio; St. Louis; Southern California; the Seattle area; Mesa, Arizona; Huntsville, Alabama; Philadelphia; Charleston, South Carolina; Salt Lake City; and Portland, Oregon.

"Boeing is proud to stand alongside many other great American companies in the fight against COVID-19, and we are dedicated to supporting our local communities, especially our front-line health care professionals, during this unprecedented time," David Calhoun, president and CEO of Boeing, says in a release.

At Port San Antonio, Boeing operates one of the world's largest military aircraft maintenance, repair, and overhaul facilities. In August 2019, Boeing said it was adding 500 jobs in San Antonio, on top of the 900 people already employed there.

Solvay, a longtime Boeing supplier, has provided clear film for the face shields. Another supplier, Trelleborg Sealing Solutions, has donated elastic for the adjustable headbands.

To date, Boeing says it has donated tens of thousands of pieces of personal protective equipment — including face masks, goggles, gloves, safety glasses, and protective bodysuits — to support U.S. health care workers fighting the pandemic.

"History has proven that Boeing is a company that rises to the toughest challenges with people who are second to none," Calhoun adds. "Today, we continue that tradition, and we stand ready to assist the federal government's response to this global pandemic."

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This article originally ran on CultureMap.

A startup and a nonprofit makerspace have rallied to create PPE, or personal protective equipment, for local hospitals. Getty Images

Houston tech community answers the call for medical equipment amid coronavirus-caused shortages

in need of PPE

In the span of one day, the founders of Houston-based Lazarus 3D received calls from emergency room directors and physicians and vice presidents of hospitals explaining a dire need for personal protective equipment — like surgical masks and face shields — for medical professionals in the front lines of the battle against COVID-19.

"We stopped everything we were doing," says Jacques Zaneveld, co-founder of Lazarus, which makes 3D-printed human organs for surgeons to practice on. "We've moved 100 percent of our focus on developing PPE."

Now, Zaneveld with his co-founder, Smriti Agrawal Zaneveld, have manufacturing orders in for 700,000 surgical masks weekly and have designed a non-FDA approved face shield, which they have ordered a few million of. The duo has taken out a short-term loan to front the cost of the medical equipment and are now looking for the right customers to buy these new PPE products. All hospitals and medical professionals in need of supplies can head to Lazarus' website to request more info.

"Our personal feeling has been to do whatever we can do to build as many as possible," Jacques tells InnovationMap. "It's very stressful because I'm borrowing money that we don't have in order to set up these production lines."

On the other side of town, 3D printing nonprofit TXRX has reprogramed 30 of its 3D printers to make PPE. The nonprofit is working Memorial Hermann to quickly prototype and test items made with materials they can get their hands on.

The Center for Disease Control has relaxed some of the requirements for PPE in light of the crisis and shortage, and Roland von Kurnatowski, president at TX/RX Labs, says that has helped speed up their efforts. But, the biggest challenge, he says, has been to quickly get together a design and prototype for Memorial Hermann to give them feedback so that they can then produce the products.

"I think there are a lot of people out there producing devices, but I think the problem is there's not a lot of clarity around materials, quality, and acceptance. People are doing what they can with what they've got," says von Kurnatowski. "Our hope working with Memorial Hermann was to make sure we are devising and testing devices that are functional and appropriate.

TXRX is also relying on Memorial Hermann and others in the medical community to indicate which PPE devices are most needed. Currently, the nonprofit is printing 10,000 face shields for Memorial Hermann, but also has designs for N95 respirators, surgical masks, a positive air pressure respirator (or PAPR), Tyvek suit, and even a portable shield for the intubation process.

Von Kurnatowski says the Houston community can get involved by donating to TXRX's GoFundMe campaign. The 3D printing process is quick and local, but expensive and out of budget for hospitals, so TXRX is taking a loss on its products it is creating. The organization is also looking for people who might have 3D printing materials or experience to volunteer — TXRX has about 20 people working on this but hopes that number ramps up to 60 to 80 people helping out.

Crisis also brings the community together in their time of need — that's what Zaneveld says he sees happening.

"Everyone who is at all involved in the medical space in engineering in Houston is trying to put stuff out," Zaneveld says. "We're sharing information and trying to work together to support each other."

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

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