The UTHealth Behavioral Sciences Center, set to open next year, will be unlike anything in Houston. Rendering courtesy of Perkins and Will

Film and TV portrayals of psychiatric hospitals have driven a narrative based in cold, clinical rooms and unwelcoming corridors. That picture couldn't be more inaccurate when it comes to Houston's first public mental health hospital in more than three decades. Breaking stigmas and setting a new bar for design, the UTHealth Behavioral Sciences Center is set to open its doors in late 2021.

UTHealth has brought on architecture firm Perkins and Will to design the upcoming mental health facility. The behavioral health campus will be the largest facility of its kind in the United States, becoming a place to train future physicians and specialists. Located near Texas Medical Center, the space will consist of two buildings connected by a glazed bridge, surrounded by a tranquil green space.

The 220,000-square-foot facility includes 264 new inpatient beds and will provide access to mental healthcare, substance use intervention and treatment, and medical care via integrated treatment programs.

"Knowing that behavioral and mental health is a critical aspect of one's holistic well-being, our team was thoughtful in approaching each design decision through research and with the interest of promoting health," says Diana Davis, principal and managing director of the Houston studio of Perkins and Will.

Creating the calm

Rendering courtesy of Perkins and Will

Each element in the space was created with the intention of creating a peaceful environment for patients and staff. From a warm color palette to scenic views, the architecture will play a role in soothing patients and offering a relaxing space.

"We were working directly with a researcher who had done a lot of work on the impact of lighting environments for helping to establish a stronger sense of circadian rhythm in the behavioral health environment," explains Davis.

Tunable lighting fixtures that can shift to warmer hues at certain times of day were one of the intentional designs featured throughout the space.

Insomnia can arise in various mental health disorders and can even be a side effect of certain medications. According to the National Alliance on Mental Illness, approximately 50 percent of insomnia cases are related to depression, anxiety or psychological stress.

"If you've ever suffered from a little bit of insomnia, you can imagine that that probably makes the treatment process that much harder. So anything we could do as design professionals to encourage a relaxing, sleeping space was very important," says Sarah Rolfvondenbaumen, a project architect at Perkins and Will.

Like light, sound can be a crucial element in creating an ambiance. The units in the UTHealth Behavioral Sciences Center is built for 24 patients — now imagine 24 patients talking in a room. "It could get very loud," says Rolfvondenbaumen, "We focused a lot on how to reduce that sound."

Rolfvondenbaumen explained how many hospital settings use two different types of acoustics that are "necessary to make a good space to be in." Sound transmission class (STC) is the measurement of how sound travels between two different spaces, and noise reduction coefficient (NRC) is a number value that describes the average sound absorption of material.

"We used a very high in our NRC ceiling tile where applicable. . .that really helps capture the sound that is bouncing around a room and displacing it instead of reflecting it back down," says Rolfvondenbaumen. The design also changes the planes of the space, avoiding the typical square layout and giving rooms non-90 degree angles.

Perkins and Will will also be collaborating with researchers at the UTHealth Science Center to research the impact of noise reduction. By comparing the space patients are in now vs. the new building, Davis hopes to conduct "a study that would show that, hopefully, by reducing the noise that we're also able to reduce adverse events and contribute to that healing environment."

Materials matter

Rendering courtesy of Perkins and Will courtesy of Perkins and Will

Outside of choosing noise-reducing materials, Perkins and Will made a commitment to using sustainable items within the facility.

"We had a very rigorous process of selecting the interior finishes to make sure that they were good for the environment or at least good for the people who are living in the space," says Rolfvondenbaumen.

Material health was a big priority because "in trying to heal people's minds and bodies, we weren't subjecting them to materials that themselves might be carcinogens or involve an excess of pollutants in the process of being created," explains Davis.

A welcoming space

Rendering courtesy of Perkins and Will

"It was really important to us in the design to deinstitutionalize the look of the building," explains Davis, "To try to keep the height down so that it felt a little less intimidating so that it felt more like it was a part of its community."

To help patients transition from the hospital setting into the outside world, the campus includes a therapy mall. Offering opportunities for patients to practice interacting in everyday life, the therapy mall was created to be used in a multitude of ways. It can serve as a salon, boutique, fitness center, movie night spot, or music therapy space.

"One of my favorite features of the building is that the way it is designed is that the shared treatment spaces that are kind of the amenity spaces that serve multiple units are located on the ground floor and all wrap around one of the courtyards," explains Davis.

The common areas like the therapy mall and dining room feature natural light and picturesque views of the tree-filled courtyard. "We were very intentional about making sure that the key locations of therapy all had that direct communication to the outdoors and that ability to see out," says Davis.

Staff perks

Rendering courtesy of Perkins and Will

The healthcare field, especially during a pandemic, can be a stressful environment with high rates of employee burnout. The CDC has even published extensive guides for healthcare workers and first responders to help overcome the stress caused by COVID-19 and the healthcare system.

More than solely a relaxing space for patients, the UTHealth Behavioral Sciences Center is designed to make work comfortable for staff members, too. The facility's Support Pavilion holds an education center as well as break rooms, on-call sleep rooms, and a mother's room for staff.

"The Support Pavilion has its own entrance so that people coming and going are preapproved," explains Rolfvondenbaumen, "They have a badge reader so that they don't have to go through security scrutinization that the public entrance has."

Planning ahead

Rendering courtesy of Perkins and Will

Every Houstonian is, unfortunately, familiar with the city's flooding woes. The UTHealth Behavioral Sciences Center project started post-Hurricane Harvey, so flooding was undoubtedly on the mind of the Perkins and Will team.

Evacuating a healthcare building is unideal, especially a psychiatric facility. Measures were taken to prevent flooding and keep the hospital running on generator power, so patients could stay safe in the building. Just below the hospital, the facility features underground storage tanks that could fill an Olympic-sized swimming pool.

While weather can be planned for, a global pandemic is far less predictable. While the project with UTHealth was started prior to the coronavirus, the space is intentionally designed to allow patients to have flexibility throughout. Patients can choose to be in larger group settings or separate themselves into a breakout room, lending itself to social distancing guidelines.

While it's unclear whether Houston will be dealing with the COVID-19 pandemic at the close of next year, research shows the lasting mental health struggles the virus is creating. Davis foresees this project contributing "in a much more significant way" due to the unfortunate "need for care that we will have following this [pandemic] because of the mental stress and strain."

While mental and behavioral health has long-held stigmas, the UTHealth Behavioral Sciences Center will be both "welcoming and inviting," says Davis.

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Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.