The UTHealth Behavioral Sciences Center, set to open next year, will be unlike anything in Houston. Rendering courtesy of Perkins and Will

Film and TV portrayals of psychiatric hospitals have driven a narrative based in cold, clinical rooms and unwelcoming corridors. That picture couldn't be more inaccurate when it comes to Houston's first public mental health hospital in more than three decades. Breaking stigmas and setting a new bar for design, the UTHealth Behavioral Sciences Center is set to open its doors in late 2021.

UTHealth has brought on architecture firm Perkins and Will to design the upcoming mental health facility. The behavioral health campus will be the largest facility of its kind in the United States, becoming a place to train future physicians and specialists. Located near Texas Medical Center, the space will consist of two buildings connected by a glazed bridge, surrounded by a tranquil green space.

The 220,000-square-foot facility includes 264 new inpatient beds and will provide access to mental healthcare, substance use intervention and treatment, and medical care via integrated treatment programs.

"Knowing that behavioral and mental health is a critical aspect of one's holistic well-being, our team was thoughtful in approaching each design decision through research and with the interest of promoting health," says Diana Davis, principal and managing director of the Houston studio of Perkins and Will.

Creating the calm

Rendering courtesy of Perkins and Will

Each element in the space was created with the intention of creating a peaceful environment for patients and staff. From a warm color palette to scenic views, the architecture will play a role in soothing patients and offering a relaxing space.

"We were working directly with a researcher who had done a lot of work on the impact of lighting environments for helping to establish a stronger sense of circadian rhythm in the behavioral health environment," explains Davis.

Tunable lighting fixtures that can shift to warmer hues at certain times of day were one of the intentional designs featured throughout the space.

Insomnia can arise in various mental health disorders and can even be a side effect of certain medications. According to the National Alliance on Mental Illness, approximately 50 percent of insomnia cases are related to depression, anxiety or psychological stress.

"If you've ever suffered from a little bit of insomnia, you can imagine that that probably makes the treatment process that much harder. So anything we could do as design professionals to encourage a relaxing, sleeping space was very important," says Sarah Rolfvondenbaumen, a project architect at Perkins and Will.

Like light, sound can be a crucial element in creating an ambiance. The units in the UTHealth Behavioral Sciences Center is built for 24 patients — now imagine 24 patients talking in a room. "It could get very loud," says Rolfvondenbaumen, "We focused a lot on how to reduce that sound."

Rolfvondenbaumen explained how many hospital settings use two different types of acoustics that are "necessary to make a good space to be in." Sound transmission class (STC) is the measurement of how sound travels between two different spaces, and noise reduction coefficient (NRC) is a number value that describes the average sound absorption of material.

"We used a very high in our NRC ceiling tile where applicable. . .that really helps capture the sound that is bouncing around a room and displacing it instead of reflecting it back down," says Rolfvondenbaumen. The design also changes the planes of the space, avoiding the typical square layout and giving rooms non-90 degree angles.

Perkins and Will will also be collaborating with researchers at the UTHealth Science Center to research the impact of noise reduction. By comparing the space patients are in now vs. the new building, Davis hopes to conduct "a study that would show that, hopefully, by reducing the noise that we're also able to reduce adverse events and contribute to that healing environment."

Materials matter

Rendering courtesy of Perkins and Will courtesy of Perkins and Will

Outside of choosing noise-reducing materials, Perkins and Will made a commitment to using sustainable items within the facility.

"We had a very rigorous process of selecting the interior finishes to make sure that they were good for the environment or at least good for the people who are living in the space," says Rolfvondenbaumen.

Material health was a big priority because "in trying to heal people's minds and bodies, we weren't subjecting them to materials that themselves might be carcinogens or involve an excess of pollutants in the process of being created," explains Davis.

A welcoming space

Rendering courtesy of Perkins and Will

"It was really important to us in the design to deinstitutionalize the look of the building," explains Davis, "To try to keep the height down so that it felt a little less intimidating so that it felt more like it was a part of its community."

To help patients transition from the hospital setting into the outside world, the campus includes a therapy mall. Offering opportunities for patients to practice interacting in everyday life, the therapy mall was created to be used in a multitude of ways. It can serve as a salon, boutique, fitness center, movie night spot, or music therapy space.

"One of my favorite features of the building is that the way it is designed is that the shared treatment spaces that are kind of the amenity spaces that serve multiple units are located on the ground floor and all wrap around one of the courtyards," explains Davis.

The common areas like the therapy mall and dining room feature natural light and picturesque views of the tree-filled courtyard. "We were very intentional about making sure that the key locations of therapy all had that direct communication to the outdoors and that ability to see out," says Davis.

Staff perks

Rendering courtesy of Perkins and Will

The healthcare field, especially during a pandemic, can be a stressful environment with high rates of employee burnout. The CDC has even published extensive guides for healthcare workers and first responders to help overcome the stress caused by COVID-19 and the healthcare system.

More than solely a relaxing space for patients, the UTHealth Behavioral Sciences Center is designed to make work comfortable for staff members, too. The facility's Support Pavilion holds an education center as well as break rooms, on-call sleep rooms, and a mother's room for staff.

"The Support Pavilion has its own entrance so that people coming and going are preapproved," explains Rolfvondenbaumen, "They have a badge reader so that they don't have to go through security scrutinization that the public entrance has."

Planning ahead

Rendering courtesy of Perkins and Will

Every Houstonian is, unfortunately, familiar with the city's flooding woes. The UTHealth Behavioral Sciences Center project started post-Hurricane Harvey, so flooding was undoubtedly on the mind of the Perkins and Will team.

Evacuating a healthcare building is unideal, especially a psychiatric facility. Measures were taken to prevent flooding and keep the hospital running on generator power, so patients could stay safe in the building. Just below the hospital, the facility features underground storage tanks that could fill an Olympic-sized swimming pool.

While weather can be planned for, a global pandemic is far less predictable. While the project with UTHealth was started prior to the coronavirus, the space is intentionally designed to allow patients to have flexibility throughout. Patients can choose to be in larger group settings or separate themselves into a breakout room, lending itself to social distancing guidelines.

While it's unclear whether Houston will be dealing with the COVID-19 pandemic at the close of next year, research shows the lasting mental health struggles the virus is creating. Davis foresees this project contributing "in a much more significant way" due to the unfortunate "need for care that we will have following this [pandemic] because of the mental stress and strain."

While mental and behavioral health has long-held stigmas, the UTHealth Behavioral Sciences Center will be both "welcoming and inviting," says Davis.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.