Work has begun on a crucial part of the Land Bridge. Rendering courtesy of Nelson Byrd Woltz

Few things get local greenspace lovers more hyped than the upcoming improvements and beautification of our beloved Memorial Park — which is currently undergoing a major transformation. While many of the updates and facelifts are years off, one of the most innovative ventures has reached a new milestone in the much-anticipated Land Bridge and Prairie project.

Installation of the first tunnel arches has started as of December 9, according to the Memorial Park Conservancy. Marked by two separate, 35-foot tall mounds, the Land Bridge will serve as a major connector for park users and wildlife between the north and south sides of the park, Additionally, it will offer new gathering spaces with scenic views of Houston and the project's expansive prairie network.

Once the project is completed, vehicular traffic will traverse a new alignment of Memorial Drive via tunnels through the Land Bridge — two tunnels below each of the mounds (one for each direction of travel), according to a press release. The arch segments now being erected south of existing Memorial Drive are for the two tunnels through the eastern-most mound.

Next up will be erection of the west mound arches; all tunnels are slated for completion and open to traffic by fall of 2021.

These tunnels boast an innovative edge. While most are built through existing hillsides or below ground, the Land Bridge tunnels will be set at the same grade as the existing roadway, prior to installation of the earthwork for the mounds, per a release. The tunnels through the east and west mound measure 400 feet and 560 feet long respectively and are made up of some 620 separate panels, each of which weighs just under 50,000 pounds.

While excitement is looming, traffic on Memorial Drive is no doubt a concern. Sources at Memorial Park Conservancy assure that Memorial will remain open throughout the duration of Land Bridge and Prairie construction. Within the project area, traffic has been reduced from three lanes to two each way.

All lanes will reopen in fall 2021 once the new Memorial Drive alignment through tunnels is complete. The new road alignment with three lanes restored each way will be complete in September 2021, while the Land Bridge is slated for substantial completion by October 2022.

Meanwhile, trees removed from the Land Bridge and Prairie project area (a major concern for locals) will be relocated in areas of the park designated for reforestation, or repurposed as either compost or toewood for streambank stabilization, in keeping with the Master Plan provisions.

The new arches are being installed on Memorial Drive. Photo courtesy of Memorial Park Conservancy

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This article originally ran on CultureMap.

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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

money moves

Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.