A new deal will give tech giant Intel the option to evaluate specific Rice-patented technologies. Photo via Rice University.

Rice University’s Office of Technology Transfer has signed a subscription agreement with California-based Intel Corp., giving the global company access to Rice’s research portfolio and the opportunity to license select patented innovations.

“By partnering with Intel, we are creating opportunities for our research to make a tangible impact in the technology sector,” Patricia Stepp, assistant vice president for technology transfer, said in a news release.

Intel will pay Rice an annual subscription fee to secure the option to evaluate specified Rice-patented technologies, according to the agreement. If Intel chooses to exercise its option rights, it can obtain a license for each selected technology at a fee.

Rice has been a hub for innovation and technology with initiatives like the Rice Biotech Launch Pad, an accelerator focused on expediting the translation of the university’s health and medical technology; RBL LLC, a biotech venture studio in the Texas Medical Center’s Helix Park dedicated to commercializing lifesaving medical technologies from the Launch Pad; and Rice Nexus, an AI-focused "innovation factory" at the Ion.

The university has also inked partnerships with other tech giants in recent months. Rice's OpenStax, a provider of affordable instructional technologies and one of the world’s largest publishers of open educational resources, partnered with Microsoft this summer. Google Public Sector has also teamed up with Rice to launch the Rice AI Venture Accelerator, or RAVA.

“This agreement exemplifies Rice University’s dedication to fostering innovation and accelerating the commercialization of groundbreaking research,” Stepp added in the news release.

Microsoft Learning Zone will incorporate OpenStax's trustworthy, peer-reviewed content. Photo courtesy Rice University

Microsoft partners with Rice University's OpenStax on AI teaching tool

group project

Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”

This week's roundup of Houston innovators includes Mitra Miller of Houston Angel Network, Richard Baraniuk of OpenStax, and Carlos Estrada of BioWell. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: Every week, I introduce you to three Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a podcast with an angel investment evangelist, an academic-turned-startup-founder celebrating a big win, and a leader of a brand new accelerator.

Mitra Miller, vice president and board member of the Houston Angel Network

Mitra Miller, vice president and board member of the Houston Angel Network, joins the Houston Innovators Podcast to share her passion for growing angel investors in Houston. Photo via LinkedIn

One of the biggest components of a well-functioning startup ecosystem is inarguably access to capital, and Mitra Miller is dedicated to enhancing education around investment and growing Houston's investor base.

As vice president and board member of the Houston Angel Network, the oldest angel network in Texas and one of the most active angel networks in the country, Miller strives to provide guidance to new and emerging angel investors as well as founders seeking to raise money from them.

"Most founders have no idea or understanding of how investors think — we are not an ATM," Miller says on the Houston Innovators Podcast. "We are really partners you are getting married to for the next 5, 8, 10 years — sometimes longer. We need to bring your allies in every sense of the word." Continue reading.

Richard Baraniuk, Rice University professor and founder of OpenStax

At an event at the Ion, OpenStax and Rice University announced a $90 million NSF-backed initiative. Photo by Jeff Fitlow/Rice

An educational technology company based out of Rice University has received $90 million to create and lead a research and development hub for inclusive learning and education research. It's the largest research award in the history of the university.

OpenStax received the grant funding from the U.S. National Science Foundation for a five-year project create the R&D hub called SafeInsights. Richard Baraniuk, who founded OpenStax and is a Rice professor, will lead SafeInsights. He says he hopes the initiative will allow progress to be made for students learning in various contexts.

“Learning is complex," Baraniuk says in the release. "Research can tackle this complexity and help get the right tools into the hands of educators and students, but to do so, we need reliable information on how students learn. Just as progress in health care research sparked stunning advances in personalized medicine, we need similar precision in education to support all students, particularly those from underrepresented and low-income backgrounds.” Continue reading.

Carlos Estrada, head of venture acceleration at BioWell

Calling all biotechnology startups. Photo via LinkedIn

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release. Continue reading.

At an event at the Ion, OpenStax and Rice University announced a $90 million NSF-backed initiative. Photo by Jeff Fitlow/Rice

Rice University's edtech company receives $90M to lead NSF research hub

major collaboration

An educational technology company based out of Rice University has received $90 million to create and lead a research and development hub for inclusive learning and education research. It's the largest research award in the history of the university.

OpenStax received the grant funding from the U.S. National Science Foundation for a five-year project create the R&D hub called SafeInsights, which "will enable extensive, long-term research on the predictors of effective learning while protecting student privacy," reads a news release from Rice. It's the NSF's largest single investment commitment to national sale education R&D infrastructure.

“We are thrilled to announce an investment of $90 million in SafeInsights, marking a significant step forward in our commitment to advancing scientific research in STEM education,” NSF Director Sethuraman Panchanathan says in the release. “There is an urgent need for research-informed strategies capable of transforming educational systems, empowering our nation’s workforce and propelling discoveries in the science of learning.

"By investing in cutting-edge infrastructure and fostering collaboration among researchers and educators, we are paving the way for transformative discoveries and equitable opportunities for learners across the nation.”

SafeInsights is funded through NSF’s Mid-scale Research Infrastructure-2 (Mid-scale RI-2) program and will act as a central hub for 80 partners and collaborating institutions.

“SafeInsights represents a pivotal moment for Rice University and a testament to our nation’s commitment to educational research,” Rice President Reginald DesRoches adds. “It will accelerate student learning through studies that result in more innovative, evidence-based tools and practices.”

Richard Baraniuk, who founded OpenStax and is a Rice professor, will lead SafeInsights. He says he hopes the initiative will allow progress to be made for students learning in various contexts.

“Learning is complex," Baraniuk says in the release. "Research can tackle this complexity and help get the right tools into the hands of educators and students, but to do so, we need reliable information on how students learn. Just as progress in health care research sparked stunning advances in personalized medicine, we need similar precision in education to support all students, particularly those from underrepresented and low-income backgrounds.”

OpenStax awarded $90M to lead NSF research hub for transformational learning and education researchwww.youtube.com

This week's roundup of Houston innovators includes Pedro Silva of Milkify, Anthony Palmiotto of OpenStax, and Brad Deutser of Deutser. Photos courtesy

3 Houston innovators to know this week

hou to know

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from femtech to edtech — recently making headlines in Houston innovation.

Pedro Silva, CEO and co-founder of Milkify

Pedro Silva of Milkify join the Houston Innovators Podcast to discuss the impact of their successful Shark Tank experience. Photo courtesy of Milkify

While Milkify's founders — husband and wife team Pedro Silva and Berkley Luck — secured partners on a popular business pitch and investment show, the entire experience almost didn't happen.

Silva and Luck, who got her PhD in molecular and biomedical s at Baylor College of Medicine, founded the company to provide breast milk freeze drying as a service to Houston-area families. Now, Milkify has customers across the country, but the duo didn't know if going through the process would be worth the investment and publicity, or if it would just be a distraction.

"The competitor in me wanted to be the first breast milk company to go on the show and to tell our story to the world — to show the world what my wife came up with that we thought was so great," Silva says on the Houston Innovators Podcast. "It was probably the scariest 45 minutes of my life." Read more.

Anthony Palmiotto, director of higher education at OpenStax

OpenStax, founded out of Rice University, has continued its growth, adding new partners and textbooks. Photo via openstax.org

In an effort to combat the hefty price tag of assigned texts, OpenStax, a nonprofit education startup out of Rice University, which is on a mission to increase educational access for all, seeks to democratize high-quality education by offering free, peer-reviewed, openly licensed textbooks for students and knowledge seekers across the globe.

This month, OpenStax will add to its 57 open education resources, or OER, titles with a full version of John McMurry's popular pre-med textbook, Organic Chemistry, under an open license to honor his late son, Peter, who passed away in 2019 after losing his battle with cystic fibrosis.

“Before the nursing books, we were doing business books,” Anthony Palmiotto, director of higher education at OpenStax, tells InnovationMap. “Murry’s book builds out our science offerings, so we're thinking about the different areas that students take that can be barriers for them to move up in education and succeed. From there, we’ll continue to think about how a free textbook can help students through that process.” Read more.

Brad Deutser, founder and CEO of Deutser

In his new book, Houstonian Brad Deutser explores how increasingly important a sense of belonging is in the workplace. Photo courtesy

Last week, Houstonian and business consultant Brad Deutser published his book, BELONGING RULES: Five Crucial Actions that Build Unity and Foster Performance. In a guest column for InnovationMap, Deutser writes of the importance of belonging in the workplace with his colleague Isabel Bilotta, managing consultant and head of learning and innovation at Deutser's learning initiative.

"Although there are many definitions out there, we define belonging as where we hold space for something of shared importance," the article reads. "It is where we come together on values, purpose, and identity; a space of acceptance where agreement is not required but a shared framework is understood; where there is an invitation into the space; an intentional choice to take part in; something vital to a sense of connection, security, and acceptance." Read more.

OpenStax, founded out of Rice University, has continued its growth, adding new partners and textbooks. Photo via openstax.org

Growing Houston tech nonprofit expands access to textbooks for college students

openstax updates

If everyone that attended a college or university were polled, they’d all likely agree that one of the worst parts of the experience was the rising costs of textbooks.

In an effort to combat the hefty price tag of assigned texts, OpenStax, a nonprofit education startup out of Rice University, which is on a mission to increase educational access for all, seeks to democratize high-quality education by offering free, peer-reviewed, openly licensed textbooks for students and knowledge seekers across the globe.

This month, OpenStax will add to its 57 open education resources, or OER, titles with a full version of John McMurry's popular pre-med textbook, Organic Chemistry, under an open license to honor his late son, Peter, who passed away in 2019 after losing his battle with cystic fibrosis.

“The author, John McMurry, granted us the ability to publish the 10th edition openly,” Anthony Palmiotto, director of higher education at OpenStax, tells InnovationMap. “So, the most widely used organic chemistry textbook went from being one of the most expensive undergraduate texts on the market (almost $100), to a free and open text, making this a watershed moment for OER.”

This school year, OpenStax is adding 16 academic institutions onto its platform, including Georgia State University, Southwest Texas Junior College, Texas A&M University-Commerce, University of San Diego, and more. It's the largest batch of new schools OpenStax has onboarded in a year, Palmiotto says in a news release.

Founded to increase access

Richard Baraniuk, a professor of Electrical and Computer Engineering at Rice University, founded OpenStax. Photo via rice.edu

OpenStax founder and director Richard Baraniuk, a professor of Electrical and Computer Engineering at Rice University, started the OER publisher in 1999 to remove financial barriers and make educational resources more widely available. Much like increasing access to McMurry’s Organic Chemistry, the goal is to continue to support both learners and educators by providing easily accessible and well-developed materials.

“Our mission is to support all learners in their educational pursuits by providing access to high-quality education,” Palmiotto says. “Richard Baraniuk founded it initially as a way for faculty and others to get their material and their knowledge in the form of textbooks and other learning materials to students.

“And then born out of that, we started this robust textbook development and course material development program where we put out the highest-quality materials we can in a way that fits the way courses are taught. Meaning convenience and scope and sequence and other needs that instructors must use textbooks. So really the access was really the start of it, increasing that and lowering barriers to education, and then a lot flowed from that.”

OpenStax’s library of OER titles, which are published under a Creative Commons Attribution license, are free and easily accessible on the go and usable on any device in multiple formats, including digital and PDF.

Funded by philanthropic supporters, OpenStax normally works to openly access five or six books per year, working mostly on introductory courses. Most recently, the Texas Higher Education Coordinating Board funded the publisher to do a series of nursing books, eight in total.

“Before the nursing books, we were doing business books,” Palmiotto says. “Murry’s book builds out our science offerings, so we're thinking about the different areas that students take that can be barriers for them to move up in education and succeed. From there, we’ll continue to think about how a free textbook can help students through that process.”

Tapping into tech

Currently, OpenStax has over 7.5 million users in the formal education space, primarily in higher education introductory courses, as well as grades K–12. Photo via openstax.org

In addition to nursing, OpenStax is working towards releasing books in data science and computer science, including programming, workplace software and, eventually, artificial intelligence.

“AI is a big deal to us,” says Palmiotto. “We're thinking about it a lot, and in the books themselves, we're incorporating as best we can how AI plays into Data Science, Computer Science and Python Programming those. We’re thinking about how AI could be used and will impact programming, for example. But the AI landscape is changing as we go, and that's another reason we don't just put out the books, we maintain them.

“So, we can continually update them. Once we publish, six months later, we can publish updates or additions to reflect what's happening in courses or in professions or in the workforce to reflect how AI is being used as new software is released and so on.”

As OpenStax continues to build on its OER title database, they are using multiple methods of outreach to reach as many people as possible. Currently, they have over 7.5 million users in the formal education space, primarily in higher education introductory courses, as well as grades K–12.

“Over 140 countries are using our material,” says Palmiotto. “We're not as easily able to track how many students have used our material in all those other countries. But that's not the point, we want to put it out there. We know it's being used. We want to help as much as possible. But it is being used in all those countries and in different ways. Some people are translating it. Some people are using it in English. Some people are breaking it up. It just depends on what they need.”

Evolving the industry

OpenStax repeatedly receives feedback from users worldwide that appreciate the openness and availability of their books. Photo via openstax.org

As much as OpenStax is a disrupter to conventional textbook publishers, they would rather work in partnership with publishers like Murry’s former house Cengage rather than outright replacing them.

“What we've tried to do with those publishers is actually partner with them and say, we know that textbook prices were too high,” says Palmiotto. “Some of them partnered with us, Cengage, Riley, some of the other publishers, like Macmillan, incorporate our textbooks into their platforms so that instructors and students have that flexibility even with those publishers.

“Not every publisher wants to do that. That's their choice. But what we've tried to do is say ‘let's make an ecosystem.’ That's what we call it and let them participate in this movement that open education has become.”

With their textbooks on an open forum, it might seem that OpenStax texts would be susceptible to hacking or other unauthorized changes. But, according to Palmiotto, there’s a safeguard to that.

“We keep the standard version,” he says. “That's why a lot of people keep using it because they know that the version that we provide will be the most up-to-date version. But it is openly licensed. So, if we see that a school wants to teach the course in a slightly different way or if they want to recombine two different books to make a different course, take biology and make human biology, or take philosophy and make ethics or something, they can do that.

“But we still retain the standardized version that we redistribute and make sure that that's the high-quality one that people can look to. So nobody is getting back to our version and changing it, but they do have the opportunity to change their own.”

After more than a decade in the space, OpenStax repeatedly receives feedback from users worldwide that appreciate the openness and availability of their books.

“We have some great stories of different learners from all over the world that are non-traditional students facing barriers,” says Palmiotto. “And having a free textbook and not having to choose between food and their book or courseware makes a huge difference in their lives. If they have this flexibility in what they have to purchase, most people appreciate that choice.”

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CPRIT hires MD Anderson official as chief cancer prevention officer

new hire

The Austin-based Cancer Prevention and Research Institute of Texas, which provides funding for cancer research across the state, has hired Ruth Rechis as its chief prevention officer. She comes to CPRIT from Houston’s University of Texas MD Anderson Cancer Center, where she led the Cancer Prevention and Control Platform.

Before joining MD Anderson, Rechis was a member of the executive leadership team at the Livestrong Foundation, an Austin-based nonprofit that supports people affected by cancer.

“Ruth has widespread connections throughout the cancer prevention community, both in Texas and across the nation,” CPRIT CEO Kristen Doyle said in a news release. “She is a long-term passionate supporter of CPRIT, and she is very familiar with our process, programs, and commitment to transparency. Ruth is a terrific addition to the team here at CPRIT.”

Rechis said that by collaborating with researchers, policymakers, public health leaders and community partners, CPRIT “can continue to drive forward proven prevention strategies that improve health outcomes, lower long-term costs, and create healthier futures for all.”

At MD Anderson, Rechis and her team worked with more than 100 organizations in Texas to bolster cancer prevention initiatives at clinics and community-based organizations.

Rechis is a longtime survivor of Hodgkin lymphoma, a type of cancer that affects the lymph nodes, which are part of a person’s immune system.

6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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