3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Tim Crain of Intuitive Machines, Chelsea Williams of Northwestern Mutual, and Nicolaus Radford of Nauticus Robotics. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from space tech to robotics — recently making headlines in Houston innovation.

Tim Crain, co-founder and CTO of Intuitive Machines

Tim Crain joins the Houston Innovators Podcast. Photo via intuitivemachines.com

It might surprise many to learn that publicly traded, NASA-backed Intuitive Machines, which has emerged as a commercial leader within lunar access technology development, had several pivots before finding its niche within space innovation.

In fact, as Co-Founder and CTO Tim Crain explains on this week's episode of the Houston Innovators Podcast, the company was founded as a space-focused think tank. Crain, along with his co-founders CEO Steve Altemus and Chairman Kamal Ghaffarian, came together in 2013 to start Intuitive Machines, which recently moved into a $40 million headquarters in the Houston Spaceport.

"At the time, our thought was, 'let's take the best of human space flight engineering processes, disciplines, and know how, and look at how we might commercially deploy that for biomedical, energy, big data, and aerospace,'" Crain says on the show. "We wanted to look at how we use great engineering for some of the hard problems outside of NASA's aerospace sphere." Read more.

Chelsea Williams, financial adviser at Northwestern Mutual

Houston-based financial adviser Chelsea Williams helps clients overcome their unique generational financial uncertainties by equipping them with tips and resources to get them on the path to financial wellness. Photo courtesy

In a guest column for InnovationMap, Chelsea Williams, financial adviser at Northwestern Mutual, shared tips on overcoming financial uncertainty across different generations.

"While the types of financial stressors might vary across generations and cities, the most important step to managing financial uncertainty is initiating a conversation with an adviser," she writes in her column. "Just like going to the doctor regularly, routine financial check-ups are incredibly important to catch financial headaches early on and stay ahead of long-term financial health." Read more.

Nicolaus Radford, founder and CEO of Nauticus Robotics

Houston-based Nauticus Robotics founder, Nicolaus Radford, celebrated an acquisition for his company. Image via LinkedIn

A Houston company that harnesses the power of robotics hardware and programing for underwater use has made an acquisition.

Nauticus Robotics Inc. (NASDAQ: KITT) announced it has acquired 3D at Depth Inc., a Colorado-based company with a subsea light detection and range, LiDAR, technology for inspection and data services. The deal closed for approximately $34 million in stock, before certain purchase price adjustments and the assumption of debt, per the news release.

“The future of subsea services lies in autonomy, data gathering, and analytics,” Nicolaus Radford, Nauticus’ founder and CEO, says in the release. “LiDAR has long since been core to terrestrial autonomy and by adding 3D’s capabilities to the Nauticus Fleet, we enhance autonomous vehicles in the offshore market. This acquisition increases the value of Nauticus’ fleet services and positions the Company to capitalize on data acquisition and analytics for subsea operations.” Read more.

Houstonians in particular expressed more stress than other communities in terms of household finances and physical and mental health. Photo via Getty Images

Houston expert on tips on overcoming financial uncertainty across different generations

guest column

Whether you’re a millennial or baby boomer, financial uncertainty is not limited by age, with new data from Northwestern Mutual’s 2023 Planning & Progress Study revealing that most Americans are losing sleep at night because of it. Houstonians in particular expressed more stress than other communities in terms of household finances and physical and mental health, according to a recent survey.

While the types of financial stressors might vary across generations and cities, the most important step to managing financial uncertainty is initiating a conversation with an adviser. Just like going to the doctor regularly, routine financial check-ups are incredibly important to catch financial headaches early on and stay ahead of long-term financial health.

As a Houston-based financial adviser, I help my clients overcome their unique generational financial uncertainties by equipping them with tips and resources to get them on the path to financial wellness.

Understanding where financial uncertainty comes from generationally

  • Gen Z: Studies have shown that even while Gen Z is the most confident that they’ll be prepared for retirement when the time comes, they still struggle with feelings of uncertainty on how to achieve their specific financial goals. In my experience, I have found that uncertainty among this age group often stems from a lack of financial literacy surrounding their finances. A recent financial literacy study revealed that Gen Z respondents averaged the lowest at 43 percent in answering finance-related questions correctly.
  • Millennials: Millennials equally suffer from feelings of anxiety about money, with 54 percent of millennial respondents in the P&P study indicating that financial anxiety causes them to feel depressed compared to just 20 percent of baby boomers. Millennials have lived through a pandemic, The Great Recession and slow economic growth, making their mental health and financial wellness a top priority.
  • Gen X: Even while financial uncertainty typically starts to recede later in life at this age, Gen X is facing a turning point as they get closer and closer to retirement. Studies have shown that most Americans believe they will need about $1.27 million to retire comfortably and yet, I see many individuals only recognizing the importance of retirement planning between the ages of 40 and 50. With Gen X holding about six times more debt than their parents did at that age, it’s important for this age group to consider some proactive debt and retirement strategies.
  • Baby boomers: This group has the lowest amount of financial uncertainty, but that doesn’t mean it is nonexistent. I hear a lot of baby boomers state that they wish they had started investing sooner or they wish they had conversations about their finances sooner. As such, this group is typically the most concerned about managing their existing assets and living comfortably for the rest of their lives.

Overcoming financial uncertainty

  • Increase financial literacy: Both millennials and Gen Z grew up in the digital age and expect their financial experiences to be reflective of that. For employers with Gen Z employees, working with a Northwestern Mutual financial adviser on resources to increase financial literacy can be a helpful first step. This could include on-demand webinars, digital toolkits and interactive online portals to access and view their finances.
  • Ensure every dollar has a job: Across all generations, it’s important to ensure no dollar is wasted. In other words, understanding how much of your income should be allocated toward expenses, retirement, savings, etc. is crucial. I typically recommend a budgeting rule that no more than half of an individual’s income goes toward expenses.
  • Initiate financial planning discussions early on: While it may seem daunting, results from the P&P study show that an average of 76 percent of individuals who work with a financial adviser have an overall boost to confidence. With Gen Z often heavily relying on family members for money management, it is important that family members from older generations encourage them to start saving or to consult with a financial adviser at a young age.
  • Take proactive steps toward your finances: No matter what age you are, there are always active steps you can be taking with your finances. Consider increasing the contribution amount to your 401(k) savings plan or working with a financial adviser to diversify your existing investments – or talk to your financial adviser about refinancing opportunities or debt strategies that tackle higher interest loans you may have.

Whether you’re in your 20s or your 50s, financial advisers are uniquely prepared to help you at any stage of your life – and overcome whatever uncertainties you may be facing.


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Chelsea Williams is a financial adviser at Northwestern Mutual. She's based in Houston and has clients across the country.

Small businesses need to factor in employee benefit options from day one — and this Houston expert has some tips. Photo via Getty Images

Houston wealth management adviser weighs in on benefit options as key for small business success

guest column

While Small Business Appreciation month has come to an end, my work in aiding small businesses achieve financial success is continuous.

In 2009, I began my career as a financial adviser recently co-founded Volante Integrated Planning, a Houston-based office of Northwestern Mutual focused on comprehensive financial planning and helping clients achieve financial freedom.

After years of working with business owners, and as a small business owner myself, I have learned the importance of offering benefits that help attract and retain talent, foster improved work habits and provide a foundation for growth. According to the annual SHRM employee benefit survey, health-related benefits and retirement plans were ranked the two most important benefits for employees. Whether you are a new small business owner or an established one, it is important to be aware of the benefit options available to you and the considerations that go into mapping out a benefits strategy.

1. Retirement plan options

The most common retirement plans available to small business owners are 401(k), simplified employee pension (SEP) IRA and savings incentive match plan for employees (SIMPLE) IRA. The SEP IRA and SIMPLE IRA provide employers the ability to save on a pre-tax basis. While there are some required contributions on behalf of any full-time employees, the SEP and SIMPLE IRA’s are often recommended for the self-employed or businesses with part-time or contract employees. The 401(k) also provides employers with a pre-tax savings opportunity and the ability to save on a Roth basis. Because a 401(k) requires additional administration and ongoing requirements, it is often a valuable tool for business owners who have more full-time employees.

2. Health care benefit options

According to the Affordable Care Act, companies with fewer than 50 employees are not required to provide health insurance. However, offering a competitive health insurance benefits package is an increasingly important strategy to help boost both new employee acquisition and retention. Following the global pandemic, health benefits have become increasingly important. According to a study by McKinsey & Company, 51 percent of employers now offer health care benefits to attract new employees with dental, vision, and short-term disability as the most important for job-seekers.

Not only are these benefits of importance to employees, they provide protection for business owners by ensuring good health and protection from illness-related lost productivity. Some health care benefits available to small business owners include health reimbursement accounts, where you make contributions to an account that can be used by employees to pay for individual health insurance policies acquired on their own. Consider hiring a broker, benefits consultant or financial adviser to help compare your options.

3. Life and disability insurance options

As a small business owner, you have a duty to your family, employees and business partners. It is often the unexpected that can derail the success of a business. To that extent, taking the steps to ensure you and your business are protected if you are unable to work is important. Disability insurance is a versatile product that can be used to protect you, as the owner, and your employees against loss of income due to the inability to work. Additionally, disability overhead coverage and disability buy-out insurance can protect the business and any business partners from an owner’s disability, ensuring that the business can still run smoothly. Life insurance is also important, and often required if seeking a business-related loan, to provide income replacement for your family and any business partners in the event of an owner’s death.

4. Get creative with your benefit options

The small business world is ever changing, which is why it is essential — and sometimes difficult — to keep up with benefit options. I encourage small business owners to get creative with their benefit options by exploring a professional employer organization (PEO) and a multiple employer welfare arrangement (MEWA). PEO is designed to help small businesses manage their administrative overhead, benefits and compliance duties. Through MEWA, small businesses are able to collaborate on group insurance benefits for a low cost. Lastly, if your family members contribute to your small business, make sure they are on the payroll and eligible for various benefits. This may allow you to increase the benefits your household takes home.

While creating a small business employee benefits plan can be tedious, it will take your small business to the next level. Consult in a CPA, business attorney, and financial adviser to help navigate what benefits are a good fit for you and your small business.

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Jennifer Steil is principal and wealth management adviser at Volante Integrated Planning, a private client group at Northwestern Mutual.

This week's roundup of Houston innovators includes Stuart Corr of Pumps & Pipes, Trevor Best of Syzygy, and Jennifer Steil of Northwestern Mutual. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from clean energy technology to financial planning — recently making headlines in Houston innovation.

Stuart Corr, executive director of Pumps & Pipes

What do Houston's three key industries — aerospace, medicine, and energy — have in common? Pumps and pipes, Stuart Corr explains. Photo via pumpsandpipes.org

Stuart Corr, executive director of Pumps & Pipes, and his team are gearing up for the organization's big annual event — which is returning to its in-person capacity. Though most people would not connect the dots on what all the health care, energy, and aerospace industries have in common, but for Stuart Corr, the connection is clear. It's all a bunch of pumps and pipes.

The Houston organization was founded in 2007 to strengthen the collaboration across Houston's three key industries. The city has NASA down the street, the world's largest medical center, and is regarded as the "energy capital of the world." Through the Pumps & Pipes network, innovators across these entities can share resources and collaborate.

"Pumps & Pipes is all about our network — about innovation on demand. It's the idea that we understand what's in other people's toolkits and innovation and technology portfolios," Corr says on this week's episode of the Houston Innovator Podcast. "Ideally, we want to use these new technologies to solve our own problems."

The event is on December 5 at the Ion. Tickets are on sale now. Read more.Read more.

Trevor Best, co-founder and CEO of Syzygy Plasmonics

Syzygy Plasmonics has raised a series C round of funding. Photo courtesy of Syzygy

Houston-based Syzygy Plasmonics closed a $76 million series C financing round led by New York-based Carbon Direct Capital.

The investment funding raised will help the company to "further development and delivery of all-electric reactor systems that eliminate fossil-based combustion from chemical manufacturing and reduce the carbon intensity of hydrogen, methanol, and fuel," per a news release.

"Closing this fundraising round with such strong support from financial and strategic investors and with commercial agreements in hand is a signal to the market," Syzygy Plasmonics CEO and Co-Founder Trevor Best says in the release. "Forward-thinking companies have moved beyond setting decarbonization goals to executing on them. Syzygy is unique in that we are developing low-cost, low-carbon solutions to offer across multiple industries." Read more.

Jennifer Steil, wealth management adviser for Northwestern Mutual

In observance of Women’s Entrepreneurship Day on November 19, a Houstonian shares her four key considerations for women who want to start their own businesses. Photo courtesy

Saturday was Women’s Entrepreneurship Day, and one Houston-based financial planner shared some tips and considerations for aspiring female founders.

In her guest column for InnovationMap, Jennifer Steil, financial planner for Northwestern Mutual, explained the importance of authenticity and advice on building the right team and support network.

"Being a female business owner has its challenges, but it is also extremely rewarding. If you’re considering starting your own business, it’s important to remember to stay true to yourself and do your due diligence to prepare for whatever unique challenges may be thrown your way," she writes. Read more.

In observance of Women’s Entrepreneurship Day on November 19, here are four key considerations for women who want to start their own businesses. Photo via Getty Images

Houston expert: 4 things female founders should know before starting a business

guest column

Almost four years ago my business partner and I started Volante Integrated Planning, a Houston-based office of Northwestern Mutual focused on comprehensive financial planning. I always aspired to run a business; however, I knew there were many factors to consider before making that leap.

According to the 2022 Northwestern Mutual Great Realization survey, 24 percent of respondents say they want to start a new business in the next two years. While starting your own business sounds appealing, leaving your current job and becoming an entrepreneur can be a difficult transition — and it’s no secret that women have to approach our career paths differently than men.

As I recognize there is no one-size-fits-all approach to starting and managing your own business, I wanted to share a few valuable lessons and key takeaways that I learned from my own experience:

1. Seek advice and counsel

When it comes to starting your own business, it’s important to go through the proper financial and legal steps. In order to do this, there are three people you should consider developing a relationship with. The first is a financial planner who can assist you in growing your business by creating a budget and finding ways to leverage your current assets to set you up for long-term success. The second is a Certified Public Accountant who has experience in your industry to help you navigate the unique intricacies of being a business owner. Lastly, an attorney who can help you draw up the necessary documents and think through what needs to be included to protect you and your family.

2. Build your team

You will always need a support system and business team to lean on no matter how much experience you have in your industry or in running a business. I knew early on that I wanted to partner with someone to make it more fun and add higher value to our clients. Before launching our business partnership, we went through varying business cycles together to ensure we would mesh well, from a value standpoint, both financially and personally. This business “courtship” is critical to ensure you build the kind of trust needed. It is also important to develop the culture and values you want for your business first and choose partners or team members that align with those values.

3. Don’t be afraid to be authentic

People are drawn to authenticity rather than if you try to fit into a box, which is why it’s important to stay true to yourself in all aspects of your business. By being your true, authentic self, you can put a plan in place to start a business that is a reflection of your values and morals. If being a working mom is a part of your identity, don’t be afraid to make that known to the team. There is nothing that says you have to start a business a certain way, so make it yours and own it.

4. Give yourself grace

As women, we have a tendency to want to do it all, but it’s important to give yourself grace and be intentional with how you prioritize your time. There are certain life factors and considerations that ultimately influence how women prepare for their financial futures, especially when it comes to running a business. If starting or managing your business is the priority at the time, it’s OK to let your social life or fitness routine, for example, take the back burner for a period of time.

Being a female business owner has its challenges, but it is also extremely rewarding. If you’re considering starting your own business, it’s important to remember to stay true to yourself and do your due diligence to prepare for whatever unique challenges may be thrown your way.

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Jennifer Steil is a Houston-based Northwestern Mutual wealth management adviser.

One in two Houstonians say they have a great business idea — and two-thirds have gotten the ball rolling on making their idea a reality. Getty Images

New data shows over half of Houston has an idea for a business

City of innovation

If you're sitting on a game-changing business idea, you're not alone. According to data from Northwestern Mutual, over half of Houstonians surveyed said they they've got something up their sleeves for a startup — and a third of that group said their idea has the capability to change the industry.

Of the respondents who said they had a business idea, almost 60 percent have already taken first steps to making their idea a reality. But for those yet to take a plunge, the factors holding these aspiring entrepreneurs back were primarily financial. More than 60 percent said not having enough finances were what's stopped them from taking the next step, while over a third indicated that they weren't sure what their next step would be. About 30 percent identified the fear of failure as what's held them back.

Similarly, when asked what the biggest hurdle in starting a company for their business idea, almost half of those surveyed said financial support, followed by "making money" with 17 percent. Of course, that's what Carrie Neumann, director of Multicultural Market Strategy at Northwestern Mutual, expected. Enter: Northwestern Mutual's financial advising services.

"A personalized, holistic plan sets business owners on track to achieve their goals, and it also puts protections — for the business, the owner and current or future employees — in place for the expected and unexpected," says Neumann in a release.

"For entrepreneurs, a trusted financial adviser is not only a great resource for the many questions that come up when starting a business, but an adviser can also help plan for the longterm."

Northwestern Mutual conducted a survey in partnership with OnePoll with a sample of 8,000 individuals in the United States. Houston was one of the 12 major metros included in the survey — and the lone Texas city. The other cities included in the survey were Chicago; Cincinnati; Denver; Miami; New York; Los Angeles; Omaha, Nebraska; Raleigh, North Carolina; Richmond, Virginia; San Francisco, and Washington D.C.

Houston skewed a tad more ambitious than the other metros surveyed. Across the sample, 41 percent of survey respondents said they have an idea for a business compared to Houston's 51.4 percent. Miami, New York City, and Los Angeles all had a higher percentage of respondents that said they had a great business idea. Los Angeles had over 60 percent of its surveyed participants respond affirmatively to that question.

The city of Houston has its advantages for entrepreneurs. A recent study shows that salaries stretch further in Houston, with the Bayou City ranking as No. 7 nationally. The study conducted by BusinessStudent.com factored in average pay of common jobs and the cost of living.

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Intuitive Machines to buy satellite maker Lanteris for $800M

space deal

Houston-based aerospace company Intuitive Machines has agreed to buy satellite manufacturer Lanteris Space Systems for $800 million from private equity firm Advent International.

Intuitive Machines co-founder, president and CEO Steve Altemus said the combined revenue of his company and Palo Alto, California-based Lanteris exceeded $850 million as of Sept. 30, and their backlog of orders totaled $920 million.

Until recently, Lanteris operated as Maxar Space Systems. Its origins date back to 1957.

The deal—comprising $450 million in cash and $350 million in Class A shares of Intuitive Machines stock—is expected to close in the first quarter of 2026.

The acquisition “marks the moment Intuitive Machines transitions from a lunar company to a multi-domain space [company], setting the pace for how the industry’s next generation will operate,” Altemus said.

Altemus said the acquisition would enable Intuitive Machines to better compete for Earth orbit, lunar, Mars and deep space projects. Among the opportunities that would open up thanks to the Lanteris deal are the proposed Golden Dome missile defense system and a large lunar lander capable of carrying astronauts, he said.

“The new Intuitive Machines will combine rapid innovation and precision spacecraft production to meet the growing demand for responsive, high-reliability space infrastructure and services,” Altemus said.

Intuitive Machines, founded in 2013, develops lunar landers and provides aerospace services. In 2024, it became the first U.S. company to land a spacecraft on the moon in half a century.

Altemus said Intuitive Machines is already building three satellites for NASA’s near-space network, and it might upsize two more satellites now that it plans to buy Lanteris.

Aside from satellites, Lanteris is developing the power and propulsion element for NASA’s Gateway, a lunar orbiting command module that will support Artemis missions and deep space exploration.


Lanteris was a division of Maxar Technologies, which Advent and minority investor British Columbia Investment Management took private in a 2023 deal valued at $6.4 billion

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Meet 6 mentors who are helping the Houston startup scene flourish

meet the finalists

Few founders launch successful startups alone — experienced and insightful mentors often play an integral role in helping the business and its founders thrive.

The Houston startup community is home to many mentors who are willing to lend an ear and share advice to help entrepreneurs meet their goals.

The Mentor of the Year category in our 2025 Houston Innovation Awards will honor an individual like this, who dedicates their time and expertise to guide and support budding entrepreneurs. The award is presented by Houston City College Northwest.

Below, meet the six finalists for the 2025 award. They support promising startups in the medical tech, digital health, clean energy and hardware sectors.

Then, join us at the Houston Innovation Awards this Thursday, Nov. 13 at Greentown Labs, when the winner will be unveiled. The event is just days away, so secure your seats now.

Anil Shetty, InformAI

Anil Shetty serves as president and chief medical officer for biotech company Ferronova and chief innovation officer for InformAI. He's mentored numerous medical device and digital health companies at seed or Series A, including Pathex, Neurostasis, Vivifi Medical and many others. He mentors through organizations like Capital Factory, TMC Biodesign, UT Venture Mentoring, UTMB Innovation and Rice's Global Medical Innovation program.

"Being a mentor means empowering early-stage innovators to shape, test, and refine their ideas with clarity and purpose," Shetty says. "I’m driven by the opportunity to help them think strategically and pivot early before resources are wasted. At this critical stage, most founders lack the financial means to bring on seasoned experts and often haven’t yet gained real-world exposure. Mentorship allows me to fill that gap, offering guidance that accelerates their learning curve and increases the chances of meaningful, sustainable impact."

Jason Ethier, EnergyTech Nexus

Jason Ethier is the founding partner of EnergyTech Nexus, through which he has mentored numerous startups and Innovation Awards finalists, including Geokiln, Energy AI Solutions, Capwell Services and Corrolytics. He founded Dynamo Micropower in 2011 and served as its president and CEO. He later co-founded Greentown Labs in Massachusetts and helped bring the accelerator to Houston.

"Being a mentor means using my experience to help founders see a clearer path to success. I’ve spent years navigating the ups and downs of building companies, struggling with cash flow, and making all the mistakes; mentoring gives me the chance to share those lessons and show entrepreneurs the shortcuts I wish I’d known earlier," Ethier says. "At Energytech Nexus, that role goes beyond just helping individual founders — it’s about creating a flywheel effect for Houston’s entire innovation ecosystem."

Jeremy Pitts, Activate Houston

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston last year. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Being a mentor to me is very much about supporting the person in whatever they need. Oftentimes that means supporting the business—providing guidance and advice, feedback, introductions, etc," But just as important is recognizing the person and helping them with whatever challenges they are going through ... Sometimes they need a hype man to tell them how awesome they are and that they can go do whatever hard thing they need to do. Sometimes they just need an empathetic listener who can relate to how hard these things are. Being there for the person and supporting them on their journey is key to my mentorship style."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard and chief information officer at Empact IT, which he also owns. He mentors through Founder Fridays Houston Group, Software Day by Mercury Fund, SUPERGirls SHINE Foundation, Cup of Joey and at the Ion. He's worked with founders of FlowCare, STEAM OnDemand, Lokum and many other early stage startups.

"Being a mentor to me means unleashing an individual’s 10x—their purpose, their ikigai (a Japanese concept that speaks to a person’s reason for being)," Alapat says. "Mentoring founders in the Houston community of early stage, high-growth startups is an honor for me. I get to live vicariously through a founder’s vision of the future. Once they show me that compelling vision, I’m drawn to bring the future forward with them so the vision becomes reality with a sense of urgency."

Neal Dikeman, Energy Transition Ventures

Neal Dikeman serves as partner at early stage venture fund Energy Transition Ventures, executive in residence at Greentown Labs, and offices in and supports Rice Nexus at the Ion. He mentors startups, like Geokiln, personally. He also mentored Helix Earth through Greentown Labs. The company went on to win in the Smart Cities, Transportation & Sustainability contest at SXSW earlier this year. Dikeman has helped launch several successful startups himself, most recently serving on the board of directors for Resilient Power Systems, which was acquired by Eaton Corp for $150 million.

"Founders have to find their own path, and most founders need a safe space where they can discuss hard truths outside of being 'on' in sales mode with their team or board or investors, to let them be able to work on their business, not just in it," Dikeman says.

Nisha Desai, Intention

Nisha Desai serves as CEO of investment firm Intention and mentors through Greentown Labs, TEX-E, Open Minds, the Rice Alliance Clean Energy Accelerator, Avatar Innovations and The Greenhouse. She currently works with founders from Solidec, Deep Anchor Solutions, CLS Wind and several other local startups, several of which have been nominated for Innovation Awards this year. She's served a board member for Greentown Labs since 2021.

"When I first started mentoring, I viewed my role as someone who was supposed to prevent the founder from making bad decisions. Now, I see my role as a mentor as enabling the founder to develop their own decision-making capability," Desai says. "Sometimes that means giving them the space to make decisions that might be good, that might be bad, but that they can be accountable for. At the end of the day, being a mentor is like being granted a place on the founder's leadership development journey, and it's a privilege I'm grateful for."

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”
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