These 10 companies are ones to look out for. Getty Images

From fast-charging batteries and hydrogen fuel alternatives to metals recycling and artificial intelligence-driven data tools, energy tech startups have a lot to offer the industry.

After nearly 60 pitches, the Rice Alliance for for Technology and Entrepreneurship named 10 startups to look out for in the energy industry. The announcement was made at the conclusion of the annual Energy and Clean Technology Venture Forum hosted at Rice University on September 11.

Of the 10, five hail from Houston. Check out this year's energy tech startups to look out for.

Sensytec

Fresh off a win from Houston's inaugural MassChallenge Texas cohort, Houston-based Sensytec again scored big. Sesnsytec's technology is known as the "smart concrete" because they've created a device that can be embedded into concrete and monitor its structure in real time. The company was founded out of the University of Houston in 2016 by Ody de la Paz.

Rheidiant

Another Houston-based company, Rheidiant uses industrial Internet of Things to optimize data from the pipelines. As a result, Rheidiant's technology can increase productivity, reduce leaks, quickly respond in emergency situations, and enhance visibility in the field. Rheidiant was founded in 2014 by CEO Murat Ocalan.

Nesh

Houston-based Nesh has created a smart assistant for oil and gas. Using artificial intelligence, Nesh can answer any question from an oil and gas employee to improve their decision-making process and cut down on the time it takes to find solutions. Nesh was founded in 2018 by Sidd Gupta and the company closed its seed round in April.

GBatteries

GBatteries, based in Ottawa, Canada, is changing the lithium battery charging game. With a mission of revolutionizing the electric car industry, GBatteries has created an artificial intelligence-backed technology that can charge a lithium battery to half full in 5 minutes. The company has 10 patents granted and 28 pending and has pilot programs in the works with automotive companies.

HARBO Technologies

Tel Aviv, Israel-based HARBO Technologies bills itself as the fastest and most effective oil spill response system in the world.The company's T-Fence system can be deployed quickly and by a team of as little as two people. HARBO was founded in 2013 by CEO Boaz Ur and has raised three rounds of funding, according to Crunchbase.

Sensorfield

It's not the first time Houston-based Sensorfield has been deemed most promising by the Rice Alliance. The company has created easy to install, wireless devices for monitoring throughout the industrial process. In May, the startup was selected for Chevron Technology Ventures' Catalyst Program.

MolyWorks Materials Corp.

California startup, MolyWorks Materials Corp., is improving the way industrial materials are recycled by building by creating a network of distributed recycling and additive manufacturing. Old metals materials go in, and metallic powder for manufacturing new products come out.

Lilac Solutions

Oakland, California-based Lilac Solutions exists to enhance lithium production as the demand rises with the growth of the electronic vehicles industry. Lilac has created a unique ion exchange technology that can lower the cost of lithium production while increasing the speed. The company is currently operating pilot programs.

Mission Secure

Mission Secure Inc. has created an industrial control system that can protect energy companies from potential cybersecurity threats as well as educate on the process. Based in Charlottesville, Virginia, MSI is venture backed and serving clients in Houston.

Syzygy Plasmonics

Houston-based Syzygy Plasmonics is fresh off a $5.8 million series A funding round it closed in August. The company is creating a hydrogen fuel cell technology that produces a cheaper source of energy that releases fewer carbon emissions. The hydrogen-fueled technology originated out of research done over two decades by two Rice University professors, Naomi Halas and Peter Nordlander. Earlier this summer, the Rice Alliance named Syzygy a most promising startup at the Offshore Technology Conference.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”