Overheard: 2024 Houston Innovation Awards finalists share top advice for fellow founders

weighing in

Clockwise from top: Lori-Lee Elliot, Anwar Sadek, Mimi Healy, Ram Prasad, Tatiana Fofanova, Prabhdeep Sekhon, Raisha Smith, and Mitra Miller.

There's a great deal of advice swirling around the world today about how to find success business. Why not take it from mentors and founders with a proven track record, like the finalists for this year's Houston Innovation Awards?

From how to grow your customer base to tips on combating funding gaps and making room for yourself at the table, they shared priceless tokens of advice in their applications for the 2024 awards.

Here's what some of the leading founders and supporters in Houston's Innovation community had to say.

"Just because you don't look like everyone else in there room, or aren't offered a seat at the table, doesn't mean you don't deserve to be there. If anything, it means the world needs you there more."

–Lori-Lee Elliott, Co-Founder and CEO of Dauntless XR, female-founded business finalist

"Don’t shy away from seeking non-traditional forms of funding like grants and non-dilutive capital, especially if VC funding seems out of reach. Surround yourself with mentors who understand your challenges, and be intentional about expanding your network to build strategic connections. Above all, stay confident in your vision, use every opportunity to learn, and never hesitate to give back by helping othersalong the way. Your success not only opens doors for you but for future generations of minority founders."

-Anwar Sadek, CORROLYTICS CEO and co-founder, minority-founded business finalist

"Being an entrepreneur is fun and hard and exhilarating and frustrating and simple and complicated and joyful and exhausting and worth it. Make a plan so you can change your plan because the market changed, because the competition grew, because your data showed something different than what you expected, because you hired or lost a team member, because you raised more money, because you didn't raise enough money. Take the time to make the plan and think about all the ways it could change, so that whenit does, it is not the first time you thought about what to do because it will be too late."

–Mimi Healy, CEO of StimulusBio, mentor of the Year finalist

"My go-to advice for entrepreneurs is to prioritize their health while building their business. It’s easy to get caught up in the hustle, but long-term success comes from sustaining your physical and mental well-being. Entrepreneurs need to be at their best to make good decisions, lead effectively, and navigate challenges, so focusing on health isn’t just a luxury—it’s essential.Another key habit I always recommend is setting aside at least one hour a day to actively find new customers. Customer acquisition is the lifeblood of any business, and dedicating this time daily can help you build momentum, create relationships, and discover new opportunities that may have been overlooked."

–Ram Prasad, CEO of Delence, minority-owned business finalist

"Learn to sit on the other side of the table and think about things from the other person's perspective. When seeking funding, this means thinking about the investor's point of view. When selling, it means thinking about the customer's POV. How are you—the founder—helping them win?"

--Mitra Miller, Vice President of Houston Angel Network, mentor of the Year finalist

"Leverage the strength of your community. And as a founder, you are the secret sauce, not the imposter. Building a network of supportive peers and mentors who understand your unique challenges can be a game-changer. At EveryDopeGirl, we've seen how powerful it is when minority founders come together to share resources, insights, and encouragement. Don't hesitate to seek out and participate in events that foster these connections. Remember, your journey is not just about overcoming obstacles, but also about celebrating your successes and the unique perspectives you bring to the table."

-Raisha Smith, founder of EveryDopeGirl, female-founded business finalist

""Focus on your strengths rather than getting caught up in perceived gaps or doubts. Embrace the diversity in your team, just as we’ve done at Gold H2, where 50 percent of our team is female and 80 percent are visible minorities. Diversity brings strength ... Trust yourself, and don’t be afraid to shape your journey in both your career and personal life."

–Prabhdeep Sekhon, CEO of Gold H2, minority-owned business finalist

"Surround yourself with two types of people: the lovers and the fighters. First, surround yourself with people that love you and believe in your vision–they'll be the ones who pick you up when your spirit takes a beating and you feel like giving up. Second, surround yourself with those who you can categorically trust to fight to the bitter end-when life happens, they'll be the ones running the ship andkeeping the dream alive while you sort things out. These will almost never be the same people, so you have to find both."

-Tatiana Fofanova, CEO of Koda Health, female-founded business finalist

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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