Houston biomedical startup granted $1.5M, Chevron taps into Plug and Play, and more innovation news

Short stories

Money moves, big deals, and more lead this roundup of innovation news. Pexels

Hitting headlines this month are innovation news stories from battling the opioid crisis and funding to TMCx companies and Houston as a whole earning recognition.

In this innovation news roundup, two Houston startups pocket some cash, Chevron links up with Plug and Play, and more.

BreviTest receives grant to combat opioid crisis

Houston-based BreviTest can rapidly and accurately test for opioid use. Photo via brevitest.com

National Institute on Drug Abuseof the National Institutes of Health — through a Small Business Innovation Research Phase II grant — has granted $1.5 million to Houston-based BreviTest Technologies to take its opioid testing technology to the next level. With 47,600 opioid overdose deaths reported in 2017 in the United States, the startup's analyzer has a lot of potential to aid in the crisis.

"Because of the delay in receiving laboratory results, many physicians use urine drug testing sparingly. The BreviTest analyzer will allow any doctor to measure opioid urine levels in-office, which will help them identify individuals who are misusing the drugs," says BreviTest's Michael J. Heffernan, Ph.D., principal investigator on the project, in a news release.

BreviTest is a Fannin Innovation Studio company. The early-stage biomedical commercialization firm that's based in Houston is proud to see the startup's success and the difference the technology is making.

"Our BreviTest team is excited to receive this support from NIDA to advance our point-of-care diagnostics technology into the clinic," said Fannin executive chairman, Leo Linbeck III, in the release. "Putting a convenient, accurate opioid test in the hands of physicians will be an important step in combating the opioid overdose epidemic facing our country."

Houston's Plug and Play operation names Chevron as founding partner

Chevron has linked up with Plug and Play in Houston. Courtesy of CTV

Plug and Play Tech Center, which just announced the participating companies in its inaugural energy and sustainability cohort in Houston, has named Chevron as a founding partner.

"We are incredibly excited to announce Chevron as a Founding Partner of Plug and Play in Houston," saysWade Bitaraf, founder of Plug and Play's Energy & Sustainability program, in a news release. "Their commitment to invest in digital transformation and reduce the environmental impact of the industry is directly aligned with our Energy & Sustainability program in Houston, Silicon Valley, and around the world."

Barbara Burger, president of Chevron Technology Ventures, the company's venture and innovation arm, is responsible for identifying pathways to innovation for the company.

"Chevron is a proud supporter of the Houston innovation community, and our support of Plug and Play's Energy & Sustainability platform demonstrates our commitment to growing the Houston innovation ecosystem," Burger says in the release. "Innovation will play a critical role in the future of energy, and our partnership with Plug and Play reinforces our commitment to invest in breakthrough technologies to enable the ongoing energy transition."

Houston recognized as a top 10 city for female founder success

According to Inc. 5000, Houston's great for female founders. Getty Images

Texas cities are great for fostering female founder success, according to a new ranking from Inc. 5000. Houston ranked at No. 10 of the top 10 list that factored in the women-led businesses among the magazine's 5,000 fastest-growing private U.S. companies.

"The Houston metropolitan area is home to 15 women-owned Inc. 5000 companies, including online marketing startup Decode Digital Marketing (No. 973) and health care staffing firm Restore Rehab Services (No. 2,645)," reads the ranking. "Together the 15 firms grew their collective revenue 142 percent between 2015 and 2018."

Dallas and Austin both appeared on the ranking, at No. 4 and No. 6, respectively.

Alice closes series A of funding

Alice founders, Elizabeth Gore (left) and Carolyn Rodz, closed their series A of funding. Getty Images

Though the company did not disclose an amount raised, Alice, an artificial intelligence-powered platform for business advice, closed a series A funding round led by SVB Financial Group, the parent company to Silicon Valley Bank.

Per a news release, the company will use the funding to "build its predictive technology, using data analytics to guide each entrepreneur through every stage of their business."

Alice, which has operations in Houston and San Francisco, reached a deal with Austin-based Bumble for funding earlier this year.

TMCx companies win big

Three TMCx alumni companies earned some recognition at the UCSF Digital Health Awards last month. Courtesy of TMCx

Three health tech companies coming out of the Texas Medical Center's accelerator program have won big at the UCSF Digital Health Awards last month.

Sana Health, member of TMCx07 in 2018, won in the best behavioral health digital therapeutic category for its light-based neuromodulation pain treatment technology.
Meru Health, member of TMCx08 in 2019, won in the best mental health digital health therapeutic category for its mental health platform.
Luma Health, member of TMCx08 in 2019, won in the best EHR-integrated platform for patient engagement category for its patient communication technology.

At TMCx's Demo Day, the cohort's companies boasted of local deals and accomplishments. Courtesy of TMC

TMCx companies plant Houston roots with pilots, partnerships, and more

Lasting impact

At the conclusion of TMCx's recent Digital Health cohort — the most international group to date — there was only one Houston company among the 19. However, most of that group have developed a presence in Houston throughout the program.

Besides just being based here in Houston for four months, TMCx associate director, Lance Black, says the city has a lot to offer these startups.

"Why Houston? Why are these companies coming from everywhere to be here? Three big reasons," he says to the crowd at Demo Day. "The size and scale of the Texas Medical Center, the diversity of Houston, and the willingness and hunger of Houstonians wanting to be involved in innovation."

From pilots and partnerships to funding and mentorship, these TMCx08 companies announced the impact they've made on Houston at the Demo Day on Thursday, June 6. Meanwhile, TMCx had its own announcement that it would create early stage programming for professionals connected to the Texas Medical Center.

"It is the TMC's mission to advance health care, research, and education. It's our mission at the Innovation Institute to bring value back to the med center through health care technology," Black says. "And, through TMCx, we do that through startup companies."

Here are some examples of TMCx companies setting foundations in the Houston ecosystem.

Virti

Photo via virti.com

California-based Virti has developed an extended reality simulation technology for training medical staff. It's a cheaper, more effective way to train personnel, says Alex Young, CEO of the company.

Virti was selected to be in England's National Health Service accelerator — the only evidence-based AR/VR training company ever to be picked for the program, says Young.

With a presence in California and England, Young says he's also planted roots in Texas too, with sales representation based in the TMCx offices.

"In the time that we've been here, we've closed deals in Texas and back in California," Young adds.

Optellum

Photo via optellum.com

Optellum is changing the way lung cancer is being detected. With the startup's artificial intelligence-enabled detection software, oncologists can better identify at-risk patients, which translates into more treatment for those in need, and less for those who don't.

The company, which is based in the United Kingdom, has raised funds abroad while networking locally.

"TMCx has been amazing for a small British company like us. We have started pilots and trials at four TMC member institutions," says Vaclav Potesil, CEO.

Oncora Medical

Photo via oncoramedical.com

Angela Holmes, the director of product and customer solutions of Oncora Medical, sets the stage at her company's Demo Day pitch by telling a story of her friend's daughter who was diagnosed with cancer. She was forced to pick between two treatment options. She had no data or insights to help.

Oncora Medical's mission is to help fight cancer using data. Though based in Philadelphia, Oncora has Houston ties, since it formed a partnership with MD Anderson Cancer Center in April of 2017.

"We are so honored and gratified to be in a strategic, multi-year collaboration with MD Anderson to build this software system to save the world," Holmes says.

PreOp MD

Cody Duty/TMC

Within health care, the projected annual aggregate surgical expenditure by 2025 is expected to be $912 billion, says Christiana Obi, founder and CEO of PreOp MD, and a Houston-based anesthesiologist. She sees lack of information causing wasted surgical resources regularly.

PreOp MD — the only Houston-based TMCx company this cohort — has an app that allows for pre-procedure education, communication, and more that aims to prevent surgical delays.

While based here, PreOp is truly rooted in Houston, and even more so with their latest news.

"We are happy and excited to say that we have landed our first medical pilot at an medical right here in town," Obi says.

RoundTrip

Cody Duty/TMC

RoundTrip has a solution to 3.6 million missed or postponed medical visits that happen annually that are inconvenient to hospitals and a major health risk to the population: Ride sharing.

The Philadelphia-based company enables all forms of transportation and puts the power in the hands of the medical institution. From ambulances to other medical vehicles, the company can optimize utilization of all vehicles to get patients to their appointments and even has a partnership with Lyft.

While completing the TMCx program, RoundTrip closed its Series A round of $5.14 million led by Virginia-based Motley Fool Ventures in April. The funds will be used for expansion.

"Now we have all this new money to expand really rapidly. Texas, we're coming for you, whether you're ready or not," says Jackson Steeger, account supervisor.

Meru Health

Photos via meruhealth.com

Meru Health is also one of the 2019 TMCx Digital Health companies that has raised money while in the program. Palo Alto, California-based Meru completed a $4.2M raise in April 2019. The round was led by San Francisco-based Freestyle Capital.

Access to mental health professionals is increasingly more difficult, so Meru Health has created a low-cost digital clinic that offers an app-based treatment program from licensed therapists. Kristian Ranta, CEO and founder, while not yet providing specifics, that they aren't done in Texas.

"I'm happy to say there's some good stuff brewing here in Texas for us. More to follow," says Ranta.

Cloud 9

Photo via cloud9psych.com

Mental health is a key contributing factor in the legal system cycle, but it doesn't have to be Liz Truong, co-founder of Cloud 9. Better educating officers and providing them with mental health resources is the best way to get them out of the hospitals and court rooms and back out in the field to protect the city.

While some police departments have instituted ride-along programs with mental health professionals that have showed success, it's expensive for the police department and risky for those professionals. Cloud 9 has created a digital solution.

"We proved this works in the Harris County Sheriff's office right here in Houston," says Truong. "Officers reported that 97 percent of Cloud 9 care was superior or equal to their current program and showed an immediate 632 percent return on investment for our customers in the same budget cycle compared to what they were already spending."

Truong also says they have other local customers they are working with, including the Harris County Health Department.

Axem Neurotechnology

Photos via axemneuro.com

Recovering stroke patients need rehabilitation to get back to 100 percent, but getting patients into the facility is challenging and at-home compliance is hard to track.

Canadian company Axem Neurotechnology has a solution. With their external device and mobile application, physical therapists can track progress and communicate with patients remotely.

"When we talk to rehab professionals, they are excited about what we're doing," says Tony Ingram, CEO and co-founder. "That's why we have leading institutions in both Canada and the U.S. onboard for clinical trials — this includes TMC's own TIRR, which is consistently ranked in the top five rehab centers in the U.S. We're collecting core baseline data in the most diverse city in the country."

Correction: A previous version of this article said Oncora's partnership with MD Anderson was formed during the TMCx program, when the partnership began in 2017.

Three companies in TMCx's current cohort are leaving the program with new funds. Courtesy of TMCx

3 TMCx companies have raised funds while completing the Houston accelerator

Extracurriculars

The Texas Medical Center's accelerator program is wrapping up its Digital Health cohort this week with the culmination of its TMCx Demo Day, and, while all of the companies have something to celebrate, three have announced that they are leaving the program with fresh funds.

Meru, Roundtrip, and Sani Nudge have raised over $10 million between the three companies. All three will be presenting at the TMCx Digital Health Demo Day on June 6 with the 16 other companies in the cohort. Click here to RSVP.

Three more TMCx companies have raised funds throughout the program but have let to formally announce their raises. Axem Neurotechnology, Optellum, and Dosentrx have collectively raised over $5 million this spring, according to TMCx.

Here's what you need to know about the three companies that have freshly padded pockets to grow their presence within the digital health industry.

Meru

Meru allows patients mental health treatment at their fingertips.Photos via meruhealth.com

Having access to health care has been an increasing issue and more and more startups are hoping they can provide solutions. Palo Alto, California-based Meru has created a low-cost digital clinic that offers an app-based treatment program from licensed therapists. The company completed a $4.2M raise in April 2019. The round was led by San Francisco-based Freestyle Capital.

Roundtrip

Philadelphia-based RoundTrip, which is in TMCx's current cohort, closed a hefty Series A round. Photo via roundtriphealth.com

An estimated 3.6 million patients miss or postpone their medical appointments annually, which leads to bigger medical issues that could have been prevented or treated earlier. Philadelphia-based RoundTrip created a platform where patients can book transportation to and from appointments. The startup closed its Series A round of $5.14 million led by Virginia-based Motley Fool Ventures in April.

Sani Nudge

Sani Nudge has optimized tech for sanitation compliance in hospitals. Photo via saninudge.com

Denmark-based Sani Nudge is one of the cohort's international members. The company's founders created a few devices that fit onto existing hospital gadgets — ID cards and hand sanitizing stations, for instance — that are able to track and monitor sanitization practices within hospitals.

According to the CDC, there are an estimated 680,000 health care-related infections in the U.S annually with a mortality rate of 10 percent.With the company's devices, hospitals can track compliance and hand sanitizing data within the hospital — but the health care professionals remain anonymous.

Sani Nudge raised $1.2 million in a round led by InQvation. The company will use the funds to grow its presence in the United States, specifically in Houston's medical center.

"Being part of the TMCx accelerator program has been game-changing," says CEO Theis Jensen in a release. "By attending a variety of workshops and hands-on events as well as receiving guidance from many experts and advisors have helped us to fully understand the US market, refine our strategies and connected us with hospitals so we can conduct studies in the TMC Medical Center".

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10+ can't-miss Houston business and innovation events for April

WHERE TO BE

From pitching competitions to expert speaker summits, April is filled with opportunities for Houston innovators.

Here's a roundup of events you won't want to miss out on so mark your calendars and register accordingly.

Note: This post may be updated to add more events.

April 4 — Mission Control: Texas’ Leadership in Space, Technology, and Innovation

Since its inception, the space industry has expanded across Texas and grown beyond scientific exploration into a tableau on which the terrestrial set have placed bets related to tourism, mining, communications, healthcare, food science, national security, technical innovations across all industries, and even human habitation beyond earth. The Texas Lyceum’s 2024 Public Conference (PubCon) will explore these opportunities and the journey to realize the promise of space and beyond for Texas and the nation.

Throughout the event, an expected 300 industry leaders and Texas legislators and staffers will participate in thought provoking discussions to inform our stakeholders and state leaders on the trajectory, challenges and opportunities in the Space Economy.

This event starts Thursday, April 4, from 2:30 to 9:30 pm at the Thompson Hotel. Click here to register.

April 4-6 — 2024 Rice Business Plan Competition

Hosted and organized by the Rice Alliance for Technology and Entrepreneurship, which is Rice University's internationally-recognized initiative devoted to the support of entrepreneurship, and Rice Business, the Rice Business Plan Competition offers an educational program mirroring real-world experience through this multi-day event for student startups from across the world.

In total, more than $1 million in investment and cash prizes are expected to be awarded at the 2024 Rice Business Plan Competition. Every single startup will walk away with at least $950 in cash prizes, no matter where they place in the competition.

The Elevator Pitch event is open to the public and on Thursday, April 4, from 6 to 9 pm at Jones Graduate School of Business. Click here to register.

April 6 — 12th Annual Houston Global Health Collaborative Conference

This meeting is an annual gathering of interdisciplinary professionals and students with a passion for global health innovation and advancement. This year's Conference Theme is Global Health Diplomacy: Shaping Policies for Health Impact and will feature subthemes of vaccine diplomacy, global surgery, the prevalence of non-communicable diseases, and the global nutrition crisis. Clinicians, researchers, healthcare workers, policymakers, and students across any field who are interested in global health are especially encouraged to attend.

This event is Saturday, April 6, from 7:45 am to 7 pm at the University of Houston College of Medicine. Click here to register.

April 10 — Bayou City Bio Pulse

Check out a showcase of life sciences in The Woodlands. This event will feature a vendor exhibition, presentations from business, academic and community development leaders, and a panel discussion on The Woodlands’ life sciences ecosystem. Spanning across five sites totaling over 80 acres, The Woodlands Innovation District is positioned to meet the needs of companies focused on in-house manufacturing (from biopharma to industrial biology), as well as contract development manufacturing organizations (CDMOs).

This event is Wednesday, April 10, from 8 am to 12 pm at the Woodlands Towers. Click here to register.

April 18 — Energy Underground: All Things Hydrogen

The Energy Underground is a group of professionals in the Greater Houston area that are accelerating the Energy Transition. Come together to learn and support each other's work in advancing the Energy Transition: make industry contacts, secure financing, share deals, recommend talent looking to enter the energy workforce, and anything else that leads to bigger, better energy companies.

This event is Thursday, April 18, from 12 to 1:30 pm at the Cannon West Houston. Click here to register.

April 19 — Build Day x Tour: Houston Hackathon

A partnership between ACT House, a human analytics leader, and Tech Equity Collective, a Google Initiative driving black innovation in tech formed an exciting new accelerator. Participants will build their own startup team, collaborate on ideas, and sprint on real work. The first place winning team will receive $10,000, the second place team will recieve $5,000 and the third place team will get $2,500.

This event is Friday, April 19, at 4 pm until April 20 at 4 pm. Click here to register.

April 21 — The Energy Corridor District's Earth Day Celebration

Come out for a day of fun and environmental awareness. Get hands-on and contribute to a communal art piece that symbolizes a collective commitment to Mother Earth. Pick up a brush or a marker and add your creativity to the canvas.

Take a moment to learn how the world's top energy companies are contributing to a more sustainable future. Get inspired and pick up some tips for your own eco-journey

This event is Sunday, April 21, from 1 to 4 pm at Terry Hershey Park. Click here to register.

April 22 — EO4Energy Workshop

The Geological Remote Sensing Group (GRSG) Americas, in partnership with the University of Houston, invites you to a workshop focusing on the role of Earth Observation (EO) and remote sensing in the Energy Industry.

As the industry moves towards sustainability, driven by Environmental, Social, and Governance (ESG) considerations, the significance of EO and remote sensing continues to grow. This workshop will encompass insightful case studies, introduce emerging technologies, and present advanced methodologies. Participants will engage with a diverse group of professionals from the energy, space, academic, and government sectors.

This event begins Monday, April 22, at 8 am at Hilton University of Houston. Click here to register.

April 25 — 2024 PIDX International US Spring Conference

In this industry event, explore the intersection of AI and Digital Standards. All experienced speakers across industries are invited to contribute articles, share use cases and theories, and connect with attendees from the Energy Industry.

The accumulated knowledge shared at the event will guide the forthcoming phase of PIDX Standards Development tailored for the Energy Industry.

This event begins Thursday, April 25, at 8 am at 501 Westlake Park. Click here to register.

April 26 — StartupLaunch USA: Ignite Your Entrepreneurial Journey

This is an immersive online learning experience tailored for aspiring entrepreneurs looking to kickstart their startup ventures in the United States. This event provides participants with the essential knowledge, skills, and resources needed to navigate the complexities of launching and scaling a successful business.

Through a series of interactive workshops, expert-led seminars, and practical case studies. Participants will learn how to develop innovative business ideas, validate market opportunities, and create viable business models that resonate with target audiences.

This event is Friday, April 26, from 1 to 6 pm at Museum of Natural Science. Click here to register.

April 27 — World Youth Foundation: STEAM Innovation Incubator

WYF's STEAM Innovation Industry Pathways, or SIIP, is a youth out-of-school-time monthly program designed to bridge the gap between academic learning, industry, and digital skilling.

Open to youth ages 6 to 24, SIIP is not your typical program—it's a gateway to a world of metaskilling, offering a dynamic range of skills from design thinking, strategic project management, soft skills development, digital skills development, and industry application.

This event is Saturday, April 27, from 10 am to 1:30 pm at Sunnyside Health and Multi-Service Center. Click here to register.

Report: Here's how Houston ranks in terms of its gender pay gap

by the numbers

It's 2024 and women are still making less money than men, thus keeping the unfortunate reality of the wage gap alive. But at least in Houston, the wage gap isn't as bad as other Texas cities, according to a new earnings study by Chamber of Commerce.

Houston ranked No. 142 on the list, which examined earnings for full-time workers in 170 of the most populous cities in the United States.

The study found that, in 2024, men in Houston are currently making $4,474 more than women — a figure that's significantly lower than the national wage gap, which is a little over $11,000.

The U.S. city with the worst gender pay gap is none other than Frisco, a Dallas suburb. Men in Frisco are currently making a staggering $52,216 more than women, which is more than $12,000 more than the gap in 2023.

Also in North Texas, McKinney remained in the No. 5 spot for the second consecutive year. McKinney men make $24,568 more than women, which is a $4,400 decrease year-over-year. Plano's gender wage gap has worsened since 2023: The Dallas suburb is now listed among the top 10 worst pay gaps in the U.S., climbing to No. 6. The study says the Plano's wage gap is now $23,415, or nearly $2,300 more than last year.

Statewide gender pay gap

Chamber of Commerce found that Texas' gender pay gap has increased since last year; The 2023 study found that women made nearly $11,000 less than men, and that discrepancy has widened in 2024 to nearly $12,000.

However, Texas' ranking has improved 10 spots from No. 29 last year to No. 19 this year.

For added context, New Hampshire has the No. 1 worst pay gap in the nation, with men making over $18,000 more than women.

Other Texas cities that earned spots in the report are:

No. 20 – Amarillo
No. 22 – Laredo
No. 24 – Austin
No. 30 – Corpus Christi
No. 31 – Pasadena
No. 33 – Irving
No. 52 – Lubbock
No. 59 – El Paso
No. 65 – Grand Prairie
No. 81 – Fort Worth
No. 118 – Dallas
No. 121 – San Antonio
No. 125 – Arlington
No. 167 – Brownsville
No. 168 – Garland

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This article originally ran on CultureMap.

3 Houston innovators to know this week

who's who

Editor's note: Welcome to another Monday edition of Innovators to Know. Today I'm introducing you to three Houstonians to read up about — three individuals behind recent innovation and startup news stories in Houston as reported by InnovationMap. Learn more about them and their recent news below by clicking on each article.

Sean Kelly, CEO and co-founder of Amperon

Amperon CEO Sean Kelly joins the Houston Innovators Podcast to share his company's growth and expansion plans. Photo via LinkedIn

The technology that Amperon provides its customers — a comprehensive, AI-backed data analytics platform — is majorly key to the energy industry and the transition of the sector. But CEO Sean Kelly says he doesn't run his business like an energy company.

Kelly explains on the Houston Innovators Podcast that he chooses to run Amperon as a tech company when it comes to hiring and scaling.

"There are a lot of energy companies that do tech — they'll hire a large IT department, they'll outsource a bunch of things, and they'll try to undergo a product themselves because they think it should be IP," he says on the show. "A tech company means that at your core, you're trying to build the best and brightest technology." Continue reading.

Amanda Burkhardt, CEO of Phiogen

Spun out of Baylor College of Medicine, Phiogen was selected out of 670 companies to pitch at SXSW earlier this month. Photo via LinkedIn

A new Houston biotech company won a special award at the 16th Annual SXSW Pitch Award Ceremony earlier this month.

Phiogen, one of 45 companies that competed in nine categories, was the winner for best inclusivity, much to the surprise of the company’s CEO, Amanda Burkhardt.

Burkhardt tells InnovationMap that while she wanted to represent the heavily female patient population that Phiogen seeks to treat, really she just hires the most skilled scientists.

“The best talent was the folks that we have and it ends up being we have three green card holders on our team. As far as ethnicities, we have on our team we have Indian, African-American, Korean, Chinese Pakistani, Moroccan and Hispanic people and that just kind of just makes up the people who helped us on a day-to-day basis,” she explains. Continue reading.

Mielad Ziaee, 2023-2024 All of Us Research Scholar

Mielad Ziaee, a 20-year-old student at the University of Houston, was tapped for a unique National Institutes of Health program. Photo via UH.edu

A Houston-area undergraduate student has been tapped for a prestigious national program that pairs early-career investigators with health research professionals.

Mielad Ziaee was selected for the National Institutes of Health’s 2023-2024 All of Us Research Scholar Program, which connects young innovators with experts "working to advance the field of precision medicine," according to a statement from UH. Ziaee – a 20-year-old majoring in psychology and minoring in biology, medicine and society who plans to graduate in 2025 — plans to research how genomics, or the studying of a person's DNA, can be used to impact health.

“I’ll be one of the ones that define what this field of personalized, precision medicine will look like in the future,” Ziaee said in a statement. “It’s exciting and it’s a big responsibility that will involve engaging diverse populations and stakeholders from different systems – from researchers to health care providers to policymakers.” Continue reading.

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