Rice University medical device spinout secures nearly $19M series A

fresh funding

Motif Neurotech, which develops minimally invasive bioelectronics for mental health treatment, closed its series A round with an oversubscribed $18.75 million. Photo via Rice.edu

A health tech startup based out of a newly formed accelerator program at Rice University has raised venture funding.

Motif Neurotech closed its series A round with an oversubscribed $18.75 million. The company, which develops minimally invasive bioelectronics for mental health treatment, was formed out of the Rice Biotech Launch Pad that launched last fall.

The round was led by Arboretum Ventures, with participation from new investors KdT Ventures, Satori Neuro, Dolby Family Ventures, re.Mind Capital and existing investors Divergent Capital, TMC Venture Fund, PsyMed Ventures, Empath Ventures and Capital Factory, according to a news release from Rice.

“Minimally invasive bioelectronics are the future of mental health treatment,” Jacob Robinson, CEO and founder of Motif Neurotech, says in the release. “Thirty percent of patients with depression don’t respond to two or more medications, and there is a significant need for additional treatment options that are effective and easily accessible."

The fresh funding will go toward developing the inaugural product, the DOT microstimulator, a wireless, battery-free device that can provide at-home therapy for treatment-resistant depression, or TRD, a major depressive disorder.

“This is a pivotal moment for the company as it closes its Series A in addition to the recent successful completion of the proof-of-concept first-in-human implant of the DOT stimulator device," Tom Shehab, managing partner of Arboretum Ventures, says in the release. "We believe Motif’s device will greatly improve the quality of life for patients who have been diagnosed with difficult to treat mental health disorders, including TRD."

Shehab, along with Amy Kruse, chief investment officer of Satori Neuro, will reportedly join Motif Neurotech's board of directors alongside Anthony Arnold, president and CEO of Sensydia Corporation, and Jacob Robinson, professor of electrical and computer engineering and bioengineering at Rice.

The Rice Biotech Launch Pad was established to take biotech innovations from concept to clinical trials in five years or less. It occupies 15,000 square feet of space on campus and is funded through federal grants and donations.

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Through a $4 million grant, the city of Houston will be able to provide mental health treatment to at-risk students. Educational First Steps/Facebook

City of Houston and local health care organizations receive $4M to treat mental health in students

Help granted

The city of Houston just received a major opportunity to help grow access to mental health treatment in children.

Thanks to a four-year $4 million grant from the United States Substance Abuse and Mental Health Services Administration, the city and its partner, Baylor College of Medicine, are launching the Be-Well Be-Connected program that provides at-risk students age six to 17 years old with mental health treatment.

The program will be led by Dr. Laurel Williams, associate professor of psychiatry at Baylor, division head for child and adolescent psychiatry and chief of psychiatry at Texas Children's Hospital. The treatment will include cognitive behavioral intervention for students with bipolar disorder and first episode psychosis, according to the release. The services will be provided in the child's home, which will ensure compliance.

"We do not have many places in Houston that have this capability to provide this level of intensity of services," Williams says in the release. "Having in-home therapy can allow the young person to stay engaged in their community and in their schools, which can promote wellness and reduction in symptoms burden more quickly."

Other Houston health centers, including Texas Children's Hospital, Harris Health System, Menninger Clinic, Harris Center, Veteran's Mental Health Care Line, Legacy Community Health Services, and DePelchin's Children's Center, will be involved with the program and the Mayor's Office of Education is the program manager of the grant.

"I created the Office of Education to support school districts in Houston because they are doing the essential work of guaranteeing that our next generation of adults is educated and ready for the future," says Mayor Sylvester Turner in the release. "The grant validates our efforts and more importantly will provide care on the frontlines of a key health issue involving young people."

Five independent school districts will also receive first level screening services and telemedical care. Families of the students receiving care will also receive support from the newly developed Texas State Child Mental Health Consortium.

"Houston and our surrounding area is primed to really take children's mental health care to the next needed level," says Williams in the release. "This SAMHSA grant opportunity coupled with the State Consortium will allow better coordination amongst services and an overall increase in available services — services that are desperately needed."

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Houston startup unveils its innovative leather alternative at the rodeo

sustainable fashion

Last month’s Houston Livestock Show and Rodeo stirred up another rootin’ tootin’ time for Houstonians and beyond.

But before the annual event galloped into the sunset, there were quite a few memorable innovations on display, with one notably coming from Rheom Materials.

The Houston-based pioneer of next-generation materials presented its scalable, bio-based alternative known as Shorai, a 93 percent bio-based leather, through two custom, western-inspired outfits that showed off cowboy flair through a sustainable lens.

“I'm a Houstonian, I love the rodeo,” Megan Beck, Rheom’s business development manager, recalls. “We're sitting there talking about it one day and we're like, ‘Okay, we've got to do something with this leather to show people how good it can look in apparel, how easy it is to wear.’”

Buoyed by the idea that their materials are meant to “change your impact, not your life,” Rheom captured the real-life energy of their bio-leather outfits under the rodeo’s neon lights in a short commercial video and photo shoot with models donning the samples, while dancing and enjoying the festivities. Rheom created a skirt, a leather jacket, and then a leather top for the look.

“Houston is such a vibrant city,” Beck says. “There's so much innovation here. I think the rodeo is just a really, really great example of that. And so we wanted to take this opportunity to take some of these garments out there and go on the slide, go on some of the rides, go into the wine garden and go dancing, because if you've ever felt some of the materials in the market in this space, they're very stiff, you can't really move in them, they're a little fragile, they kind of fall apart.”

Not only do the models in the video look fashionable, but they also look comfortable, and the leather looks natural and supple. And to the naked eye, Shorai appears to be like the leather most wearers are accustomed to.

“What we really wanted to showcase in this is the energy and the movement of the leather, and to show people how good it can look in apparel, and how easy it is to wear, which I think we were able to accomplish,” Beck says.

Next up, Beck says Rheom wants to scale production of Shorai, the Japanese word for “future,” at a competitive price point, while also reducing its carbon footprint by 80 percent when compared to synthetic leather. According to Beck, Rheom plans to see Shorai products come to market sometime this year.

“We have companies globally right now that are testing materials, that are prototyping, that are making garments, making handbags and footwear, and making eyewear because we have a plastic, as well,” Beck says. “So, this year, I do believe we'll start seeing those products actually come to market, which is very, very exciting for us.”

And with their large-scale production partner already set up for Shorai, Rheom plans to start its first production run of the product soon.

“In April, we'll actually be starting our first production run,” Beck says. “We'll be doing it at full scale, full width, and a full run of materials. So over the next five years, we're only going to just try to increase that capacity.”

Texas is home to second largest population of millionaires in the U.S.

The Millionaires Club

Tilman Fertitta, Elon Musk, Alice Walton, and Jerry Jones are members of the billionaires club in Texas. But just how many millionaires does the Lone Star State boast?

Altogether, 73,930 Texans were classified as millionaire tax filers in 2022, according to an analysis of IRS data by digital marketing firm Hennessey Digital. (For context, that millionaire count is just a few thousand shy of the entire population of Missouri City.) This figure puts Texas in the No. 2 spot for the country’s biggest population of millionaire taxpayers, behind first-place California.

However, if you crunch the figures a different way, Texas’ millionaire status isn’t quite as impressive, demonstrating that not everything is bigger in Texas. Texas ranks 10th among the states with the highest proportions of millionaire taxpayers, the study indicates. According to Hennessey Digital’s calculations, 27.1 of every 10,000 Texas tax filers reported adjusted gross income of at least $1 million for the 2022 tax year.

“The state’s booming economy, driven by energy, technology, and business-friendly policies, contributes to its wealthy population,” says Hennessey Digital.

Forbes ranked 43 Texans among the 400 wealthiest Americans last year, with Elon Musk topping the list. Houston hospitality king, Rockets owner, and newly appointed ambassador to Italy Tilman Fertitta was the 12th richest Texan and the 99th richest person in the United States, according to Forbes.

Which state comes out on top for the largest share of millionaire taxpayers? Connecticut, with 44.76 millionaire tax filers for every 10,000 filers, the Hennessey study shows. A number of well-to-do Connecticut suburbs are situated just a commuter train ride away from New York City, where bankers, brokers, and others pull in the big bucks. (Connecticut sits two spots above New York state in the millionaire ranking.)

The numbers in the study “highlight the diverse economic landscapes across our nation. States with favorable tax policies and thriving industries tend to attract more high-income earners,” says Jason Hennessey, CEO of Hennessey Digital. “Understanding these patterns can provide valuable insights for businesses and individuals making decisions about where to live, work, or invest.”

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This story originally appeared on our sister site, CultureMap.com.

Remote workers in Houston earn far more than commuters, data shows

by the numbers

In the Houston metro area, it pays to work from home.

Data published recently by the U.S. Census Bureau shows remote workers in the Houston metro earn 40 percent more than their commuting counterparts. For remote workers in the Houston area, median earnings stood at $67,500 in 2023, compared with $48,200 for other workers.

Federal data cited by Visual Capitalist indicates 11.8 percent of the Houston area’s labor pool, or nearly 460,000 people, were remote workers in 2023.

In the Dallas metro area, the difference in median earnings between remote workers and non-remote workers is even more stark. According to Census Bureau data, remote workers there earned $77,000 in 2023 — 50.7 percent more than the $51,100 for traditional workers.

Why the wide gap in pay? The Census Bureau says remote workers are more likely to be older, more likely to be white and less likely to live below the poverty line. All of these traits contribute to higher income.

Among home-based workers in the country’s five biggest metros, median earnings for remote workers were highest in the New York and Chicago areas (over $80,000) and lowest in the Houston area (under $70,000), according to the Census Bureau.

The five-metro comparison also reveals that the Houston area had the highest share (6.8 percent) of all workers, both remote and non-remote, living below the federal poverty level.

In a recent Substack post, urban planner Bill Fulton notes that remote workers in major cities typically earn 50 percent to 80 percent more than other workers do. He declares that “remote workers are far more affluent than everybody else. They are, of course, office workers, not blue-collar or service workers, and they tend to be more highly educated.”
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