3 Houston innovators to know this week

Who's who

This week's Houston innovators to know includes Juliana Garaizar of Greentown Labs, Derek Armstrong of Armstrong Innovations, and Megan Siliainoff of Med Meg Creative Services. Courtesy photos

It's a new month and Houston's innovation ecosystem is continuing to grow amid the coronavirus pandemic. This week's Houston innovators to know roundup reflects that growth with a new-to-town incubator's newly names leader — plus an entrepreneur creating an virtual reality app to escape and a communications expert's advice on navigating COVID-19.

Juliana Garaizar, launch director of Greentown Houston

Juliana Garaizar is working to help set up Houston's Greentown Labs incubator with diversity and inclusion in mind. Courtesy photo

Juliana Garaizar has had to keep a huge secret for a while. The launch director of new-to-Houston Greentown Labs has known about the cleantech incubator's plan to expand to the Bayou City for a while, and now the news is out. Of course, launching amid a pandemic isn't ideal, but Garaizar says its allowed a strong relationship with the original group based in Boston to form.

"I think the silver lining of this COVID-19 experience is that we are much more integrated with the Boston team, and we're learning at a much faster rate," she says. "That's why we decided to also open Houston for virtual memberships before we open our building in Q1 of 2021."

Garaizar joined the Houston Innovators Podcast last week to share her experience with the organization and how she'll be setting up Houston operations with diversity and inclusion in mind. Read more and stream the episode.

Derek Armstrong, CEO and founder of Armstrong Innovations

Derek Armstrong, a Houston native, founded his design company, Armstrong Innovations. Photo courtesy of Oculus Go

Derek Armstrong had been working on a new virtual reality app for relaxation and meditation that users can enter into for an opportunity to escape reality for a bit — little did he know that was something more people than ever would want to do.

His company, a Houston-area industrial design startup, Armstrong Innovations, just launched two Oculus Go app games, aptly named 'Escape'. The VR app was designed with relaxation and meditation in mind but has doubled as a new way to relax and sightsee without leaving your home during the COVID-19 pandemic.

"The sights and sounds of our new app assist with mindfulness and meditation," says CEO and founder Derek Armstrong. "It's about focusing on the sights and sounds, especially with the virus growing. It's a quick getaway without having to physically go anywhere." Read more.

Megan Silianoff, founder and creative director of Mad Meg Creative Services

Megan Silianoff has been helping clients navigate communications during a pandemic. Courtesy photo

The worst part of contracting COVID-19 — aside from suffering from the disease itself — is diligently communicating the risk of exposure to people you've been around especially to coworkers, employees, clients, etc. In a guest article for InnovationMap, Megan Silianoff of Mad Meg Creative Services, sets the scene for you to be prepared should you find yourself in this situation,

"We understand as communication experts, informing a client, boss, or anyone that you've potentially exposed them is scary messaging to share," she writes. "Guilt is the number one emotion people report experiencing when they realize they've potentially exposed someone or a group of people, even though the respective exposure was inadvertent. Nevertheless it's crucial to communicate the exposure quickly and effectively as that's how Houston can hinder the spread of this disease through our city." Read more.

It's important to craft an informative and considerate message when sharing news of a COVID-19 exposure. Getty Images

4 COVID-19 messaging tips from Houston communications expert

guest column

Houston is undoubtedly hitting critical mass with COVID-19. The common sentiment has transitioned from "knowing someone who knows someone that has COVID-19" to more frequent first-hand, anecdotal experiences. When a potential exposure happens in the workplace it's vital that employees and companies alike quickly, professionally, and responsibly inform any parties that could have been indirectly exposed including vendors, clients, or meeting participants of any kind.

We understand as communication experts, informing a client, boss, or anyone that you've potentially exposed them is scary messaging to share. Guilt is the number one emotion people report experiencing when they realize they've potentially exposed someone or a group of people, even though the respective exposure was inadvertent. Nevertheless it's crucial to communicate the exposure quickly and effectively as that's how Houston can hinder the spread of this disease through our city.

So, how have we been counseling our clients as these potential exposures arise? Here are some notes and even an email template that Houstonians can use to help get them started.

Respond quickly

This is not a time to wait for certainty. Do not wait for tangible test results or any type of certitude (such as you experiencing symptoms first-hand) before notifying a person or company that you've potentially exposed them. Remember: you aren't telling someone you gave them COVID-19, you are simply telling them that you have been exposed and therefore inadvertently exposed them.

Be honest and forthcoming with information

This is not a time to offload or dwell on your feelings of guilt, albeit that's a natural emotion. A simple apology for the situation you collectively find yourself is appropriate but a deep into your own feelings and context for the situation is neither necessary nor helpful. Remember, during times of crisis, people don't remember what you said, but that you said something at all when it would have been easier not to and that you're someone of high morals and character.

Be detailed, but not too detailed

Again, you want to share concrete information versus your own personal emotions and feelings surrounding the incident. Pertinent information includes the following;

  • When and where you were exposed
  • When and where you exposed others
  • If you're currently experiencing any COVID-19 symptoms
  • Pertinent test results (if any) in regards to how you were exposed

Work from a template

Salutation:


It has come to my attention on date that I was exposed to COVID-19 through home, work, office, etc.

Because of this, it's a possibility that I unknowingly exposed you at date and place of interaction.

Though I am not currently not experiencing any symptoms and feel healthy, I wanted to let you know about this and err on the side of caution.*OR*I currently am experiencing symptoms of Covid-19 including X,Y, Z. I plan to get tested and can let you know the results when I receive them.

I apologize for this situation and am here to answer any further questions that might help you determine how to proceed accordingly.

Sincerely,
Name

------

Megan Silianoff is the founder and creative director of Mad Meg Creative Services, a Houston-based firm specializing in public relations, social media management, web design, and branding.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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