Vanessa Wyche is the first Black woman to lead a NASA center. Photo courtesy of NASA

NASA's Johnson Space Center in Houston has witnessed a universe of history-making moments. There's now another milestone to add to the list.

On June 30, Vanessa Wyche was named director of Johnson Space Center, becoming the first Black woman to lead a NASA center. Wyche had been acting director since May 3.

"Vanessa is a tenacious leader who has broken down barriers throughout her career," Pam Melroy, deputy administrator of NASA, says in a news release. "Vanessa's more than three decades at NASA and program experience in almost all of the human spaceflight programs at Johnson is an incredible asset to the agency. In the years to come, I'm confident that Houston will continue to lead the way in human spaceflight."

As director of Johnson Space Center, Wyche now leads more than 10,000 NASA employees and contractors.

"As the home to America's astronaut corps, International Space Station mission operations, the Orion and Gateway programs, and a host of future space developments, Johnson is a world leader in human space exploration and is playing a key role in the next giant leaps in American excellence in space," Wyche says. "I look forward to working with everyone as we push forward to the moon and inspire a new generation of explorers to reach for the stars."

Before being named acting director of Johnson Space Center, Wyche had been deputy director since August 2018. Wyche, a 31-year NASA veteran, also has served as assistant director of the center and director of the center's Exploration Integration and Science Directorate, worked in the executive office of the NASA administrator, served as a flight manager for several space shuttle missions, and has led other center-level technical organizations and programs. The South Carolina native holds bachelor's and master's degrees from Clemson University.

Wyche succeeds Mark Geyer as director of Johnson Space Center. Geyer stepped down in May to focus on his cancer treatment. He had led the center since 2018 as its 12th director. In a video released in May, Geyer said he had been coping with an unidentified form of cancer for about 12 months.

Geyer remains with NASA as a senior adviser to the agency's associate administrator.

NASA Administrator Bill Nelson simultaneously announced Wyche's appointment and Janet Petro's appointment as director of Kennedy Space Center in Florida.

"Both Vanessa and Janet are exceptional leaders who will help propel NASA forward as we venture farther out into the cosmos than ever before," Nelson says. "It's an incredible time at NASA, and with Vanessa and Janet leading the Johnson and Kennedy space centers, NASA will embark on a new era of space exploration — starting with the Artemis I launch to the moon later this year."

Nelson, a former U.S. senator from Florida, became NASA administrator in May following his nomination by President Biden. During his congressional tenure, Nelson was one of NASA's staunchest advocates and even flew aboard the Columbia space shuttle. He succeeds acting NASA Administrator Steve Jurczyk. Jurczyk ran the agency after the departure of Bridenstine in January, at the end of the Trump presidency.

In 2019, Texas Comptroller Glenn Hegar reported the nearly 1,700-acre Johnson Space Center generates an economic impact of $4.7 billion in Texas and supports more than 52,000 jobs.

"NASA's history is intertwined with Texas' history, grit, and can-do spirit, and NASA's future in Texas will be crucial in building tomorrow's Texas economy," Hegar said at the time.

NASA Administrator Jim Bridenstine joined the Greater Houston Partnership for the State of Space online event this week. Photo via NASA.gov

Overheard: NASA administrator shares Houston's potential as a commercial space hub

eavesdropping online

The Greater Houston Partnership hosted its inaugural State of Space event featuring a keynote address by Jim Bridenstine, NASA administrator, that touched on the many ongoing projects at Houston's Johnson Space Center.

The online event, which also featured speeches from GHP President Bob Harvey and JSC Mark Geyer, took place Tuesday, December 15, for GHP members and nonmembers alike.

In his address, Bridenstine discussed the commercialization of space, how politics have affected the agency's history, and the exciting projects underway — including returning man to the moon. Missed the discussion? Here are some significant overheard moments from the virtual event.

"Houston is a city that chooses to take on humankind's boldest challenges head-on, and through that work we have built Houston as a technology-oriented city."

— Bob Harvey, president and CEO of the Greater Houston Partnership. Harvey called out, specifically, the Johnson Space Center and its history as the mecca for human space flight, as well as the emerging Houston Spaceport, which hopes to combine innovation across industries, from space to energy and life sciences.

"In fiscal year '21, NASA will see the first two lunar landings of the agency's Commercial Lunar Payload Services — this is an initiative led in Houston where American companies will serve science and technology payloads to the surface of the moon to prepare for human missions."

— Mark Geyer, director of JSC. Geyer mentions this initiative specifically, as well as 2020's collaboration with SpaceX to have the first American launch since 2011. Geyer also calls out NASA's new Commercial Crew Program. "All of these things position Houston to be a leader and a focal point for this new commercial space ecosystem, which is national and global in nature," Geyer says.

"We are very fortunate to have a center like Johnson in a city like Houston — a city that produces talent, that has an amazing workforce, a dedication to education and to the STEM fields."

— Jim Bridenstine, NASA administrator. Bridenstine, a Rice University alumnus, adds that the JSC currently has more programs and projects under development at any point in history.

"Johnson is focused like a laser on Mission Control. ... The No. 1 project NASA has, which we celebrated last month, is 20 years of humans working and living in space continuously."

— Bridenstine says, noting some of the continued missions like Artemis, which will return humans to the surface of the moon, and Gateway, an outpost orbiting the moon to support continued human space exploration.

"Our goal is to put an American flag on Mars — the moon is the proving ground, and Mars is the destination."

— Bridenstine says regarding NASA's focus on returning to the moon.

"I am judging my time as NASA administrator based on whether or not — when my children are my age — we are still on the moon and on Mars."

— Bridenstine says. He notes that part of moving forward is looking back and learning about programs got canceled and why, and which ones were sustainable and why. In some cases, says Bridenstine, who served in U.S. Congress for five years, it was due to divisive politics.

"The Johnson Space Center is quite well positioned for attracting a lot of commercial industry and international partners."

— Bridenstine says when asked about Houston's potential for attracting space business. He mentions how crucial Houston-based Mission Control is and always has been, as well as the emerging focus on Gateway, which will be open for other countries to be supported by. "I think Houston is in great shape — between Mission Control and the Gateway."

Mario Diaz, CEO of the Houston Airport System addresses the crowd gathered to celebrate the Apollo 11 anniversary this weekend. Natalie Harms/InnovationMap

Overheard: Aerospace and airport VIPs commemorate Space City Month at IAH

Out of this world

Houston, we have liftoff of a space-filled weekend. Saturday, July 20, marks the 50th anniversary of Apollo 11 touching down on the moon, and that calls for a celebration, as well as a commemoration.

Houston First, Space Center Houston, NASA, and United Airlines teamed up to host an international delegation at George Bush Intercontinental Airport in Terminal C on July 17. Various space or Space City VIPs took the stage to discuss their memories of the lunar landing and the role Houston played in the monumental event.

“Our hope is to be an airport system that reflects Houston’s role as a leader on the global stage and to have our city standing as truly international business and cultural center. With both Bush and Hobby airports having earned four-star ratings, we are built to meet those expectations.”

— Mario Diaz, executive director at Houston Airport System. Bush Intercontinental Airport is also celebrating its 50th anniversary since opening in 1969.

“It is the innovative spirit of the people of this city that help give the world our new perspective. We are all neighbors, and we must all face the future as one. How wonderful that understanding is now with Houston having become the nation’s most diverse city in the country with one in four Houstonians being foreign born.”

— Houston Mayor Sylvester Turner, referencing a ranking released earlier this year.

“This week, we are celebrating this anniversary and time when we did so much more than we thought we could. … [the Apollo mission] was an inspiration to us then, and I think continues to be an inspiration to all of us even now.”

— Peggy Whitson, former NASA astronaut who holds the record for the United States for her 665 days in space.

“Houston is the Space City, because the Johnson Space Center is the home of human space flight. As you know, ‘Houston’ was the very first word spoken from the surface of the moon. And, it wasn’t a fluke. They knew who they needed to talk to, and it was Houston.”

— Mark Geyer, director of NASA's Johnson Space Center.

“In roughly three years, we will have astronauts back in the region of the moon — this time women and men. And soon after that, back onto the surface of the moon again in our mission called Artemis.”

— Geyer continues to say of NASA's lunar exploration plans.

“Just a few weeks ago, [Space Center Houston] inaugurated the completely restored mission control operations room from the Apollo era. We’ve done a restoration and taken it back to the 1960s, and it appears as if the flight controllers just got up to take a break.”

— William Harris, CEO of Space Center Houston. The organization is NASA's official tourism arm and houses 250,000 square feet of indoor and outdoor exhibition space.

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3 Houston incubators and accelerators fueling the growth of local startups

Meet the finalists

It takes a village to launch a business. That's where Houston's network of incubators and accelerators can step in, providing the resources, mentorship and community needed to push a fledgling company forward.

As part of our 2026 Houston Innovation Awards, the Incubator/Accelerator of the Year category honors a local organization that is championing and fueling the growth of Houston startups.

Three incubators and accelerators have been named finalists for the 2026 award. They support startups ranging from hard-tech companies to food and youth concepts.

Read more about these organizations below. The 2026 winners will be announced on InnovationMap.com in mid-November.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced in 2024, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its third Houston cohort this summer.

The two-year program graduated its first class of Houston fellows in 2026 and saw its first alumni IPO from Houston-based Fervo Energy, which previously participated in a Berkley cohort. Nationally, it has supported 346 fellows and 276 companies since 2015. Those companies have raised more than $6 billion in follow-on funding, according to Activate. In Houston, it has supported Houston startups like Solidec, FlowCellutions and Orbital Arc. Activate Houston is led by managing director Jeremy Pitts, who co-founded Greentown Labs in Boston. It is based out of the Ion.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with members spanning 72 countries. Launched in 2018, Impact Hub Houston says its membership tripled by the beginning of 2026. This year brought major milestones for the community, including the launch of its Ideas to Impact Accelerator, which supported 11 founders across the health, education, food systems, civic technology and workforce development sectors. It also received funding from more than 20 international Impact Hubs to develop SYNC, a collaboration platform that 25 Impact Hubs across five continents have committed to pilot. The organization has worked with local startups including Myoviva Health, The Change Lab and INNERVERSE Inc.

MarMo Innovation

Galveston-based business incubator MarMo Innovation is focused on removing barriers to entrepreneurship. It aims to provide affordable space, education, mentorship, market access, connections and real-world opportunities that help entrepreneurs move from idea to launch to sustainable growth. The "industry-agnostic" incubator was founded in 2022 and is led by Executive Director Erica Delgadillo.

This year, the organization moved from primarily serving as a coworking and community space into a more comprehensive entrepreneurial incubator by expanding its MarMo Market, MarMo Market Jr. and Lunch LineUp programs. A major focus for MarMo is food entrepreneurship. It is developing an Incubator Kitchen, which MarMo says will support programs like its Cottage to Commercial Bootcamp and Food Biz 101. The organization also expanded its board this year and says it is diversifying its revenue through memberships, events, markets, equipment and space rentals, sponsorships, grants and new entrepreneurial programming.

Baylor College of Medicine launches VC fund to invest in biotech startups

fresh funding

Houston’s Baylor College of Medicine just unveiled a new venture capital fund that backs early-stage biotech startups—and it’s already made its first investment.

BCM Legacy Fund I, funded by philanthropies, invested an undisclosed amount in Houston biotech startup Nemea Therapeutics. Nemea, a spinout of the Baylor College of Medicine and Germany’s Lead Discovery Center, is developing an oral drug to treat metastatic triple-negative breast cancer that no longer responds to currently available therapies.

This type of aggressive cancer spreads from the breast to other areas of the body, such as the bones, liver, lungs or brain. Roughly 38,000 to 57,000 Americans are diagnosed each year with metastatic triple-negative breast cancer. One study showed about half of patients survive past the one-year mark following diagnosis and about one-third survive two years.

“Baylor College of Medicine’s laboratories produce discoveries with the potential to change patients’ lives, and too many of them stall where academic funding ends and private investment has not yet begun,” Dr. Jakub Tolar, president, CEO and executive dean of the Baylor College of Medicine, said in a press release. “The BCM Legacy Fund fills that gap, giving our scientists a path to advance their discoveries to patients.”

The National Institutes of Health awards more than $36 billion per year for biomedical research in the U.S., Baylor said. But some biomedical discoveries “never leave the starting line because they don’t yet fit the economics of venture capital,” the college said.

“The forefront of a new model”

The BCM Legacy Fund aggregates philanthropic capital from private foundations and donor-advised funds. It then invests in startups so they can move beyond that starting line and into later-stage investment rounds. The Greater Houston Community Foundation is the fund’s philanthropic partner.

“It’s exciting to be on the forefront of a new model for philanthropic capital,” said Houston entrepreneur and investor Burton Hanson, managing partner of the fund.

“Not only do we hope to solve a real problem by advancing these therapies to the patients who need them most, but we also hope this model will inspire others in the city and beyond toward philanthropic creativity and a posture of ‘I sacrifice; we win.’”

The fund expects to invest in about 15 early-stage startups over a five-year span. Baylor declined to divulge the amount of money in the fund and the size of the investment in Nemea.

Nemea’s “world-class chemistry”

Hanson oversees the Baylor fund alongside Chicago investor Steve Lehmann, who led the University of Chicago’s Innovation Fund.

Lehmann said Nemea, the fund’s first portfolio company, “has world-class chemistry, Baylor biology, and patients with no good options. Our job is to fund the experiments that carry it to the next handoff, so that industry and later-stage investors can take it from there.”

Based at Houston’s massive Texas Medical Center, Nemea plans to start clinical trials next year in collaboration with Baylor’s Lester and Sue Smith Breast Center.

Nemea previously received $9 million from the Lead Discovery Center and a $1.6 million grant from Baylor. Last year, the startup said it was seeking $25 million to $30 million in seed and Series A funding.

Debra McCoy of Houston, a former managing director at BlackRock and former partner at Bain & Co., and Paul Thomas, co-founder and CEO of Spring-based benefits manager Luscinia Health, sit on the Baylor fund’s governing board. Dr. Paul Klotman, former president, CEO and executive dean of Baylor, is a senior strategic adviser.

How does the fund find investment targets?

The Baylor Legacy Fund relies on two tools to help unearth early-stage biotech startups:

  • High-resolution “innovation maps” of research institutions. These maps surface hidden clusters of innovation, identify rising-star researchers and tie pockets of “innovation supply” at Baylor to areas of “innovation demand” in biotech.
  • AI-enhanced due diligence. AI agents assist with due diligence of early-stage biotech startups. The fund says the platform “distills the frameworks we’ve developed over a decade of teaching and investing into a flexible … diligence environment.”

MD Anderson unveils $3.4B expansion with two new Houston cancer care facilities

major expansion

The cutting edge of cancer-fighting technology and science is getting even sharper after MD Anderson announced last week that it will open two new facilities in the Texas Medical Center within the next five years. Inspiration Tower and Prism will expand MD Anderson’s annual patient load in the TMC to 250,000 annually and will incorporate a variety of new techniques.

The $3.4 billion project will add 2 million square feet to MD Anderson's TMC footprint, bringing its total campus size to 22 million square feet by 2032. Located at the corner of Fannin Street and Holcombe Boulevard, the cancer center says the two new facilities will serve as its new "front door" to the TMC.

“Every detail of these buildings, from the technology to the treatment rooms, was designed around our patients who will receive their care in them and our employees who will work in them. The facilities will serve as a physical representation of hope for the patients and their families who will walk through the doors,” Dr. Jeffrey E. Lee, president ad interim of UT MD Anderson, said in a news release. “Inspiration Tower and Prism are the future of cancer care, and we are grateful for the longstanding support and guidance we’ve received from the UT System Board of Regents to bring these projects to life. These facilities are part of the most impactful capital expansion in UT MD Anderson’s history.”

Prism is especially exciting as it will represent fully half of the linear accelerator treatment in the TMC. Linear accelerator is a radiation treatment that uses magnetically charged fields to deliver targeted external radiation therapy, like shooting cancer with a rail gun. The treatment is safer and has fewer side effects than older radiation treatments.

In addition, Prism will contain 12 MRI machines, four CT scanners, two PET-CT units, 18 radiation vaults and seven radiation simulators. Patient comfort has also been put at a premium with multiple gardens and roof overlooks.

“Every patient we treat deserves an environment that reflects the excellence of the care they receive at UT MD Anderson,” Chris McKee, executive vice president and chief strategy officer at UT MD Anderson, added in the release. “Our new facilities will be innovative, agile, adaptable and beautiful, and they will allow us to care for more patients, more effectively – in an environment that enhances healing and well-being. We are building for our future and for every patient who will be counting on us.”

Prism is slated to open in 2030.

Inspiration Tower will have 25 floors of surgical, diagnostic, and treatment services. At 1.4 million square feet, it’s currently expected to be the largest cancer-specific treatment facility in the United States. The tower will be divided into units for specific types of cancer, making it easy to integrate the advancing research being done all over Houston.

Like Prism, Inspiration Tower is specifically designed to offer comfort and reassurance, with more garden space, terraces, and beautiful scenery to ease patient distress. It is expected to open in 2032.