3 Houston innovators to know this week

Who's Who

These three movers and shakers in innovation are ones to know going into this week. Courtesy photos

This week's Houston innovators to know covers all the bases, from a freshly started startup to one that closed a multimillion-dollar raise. Here's who in Houston innovation that you need to know.

Joe Alapat, CEO of Liongard

Houston-based Liongard has fresh funds thanks to a $4.5 million round. Courtesy of Liongard

Joe Alapat has something to celebrate. His Houston-based startup, Liongard — an Information Technology automation and management company — closed its Series A round of funding with an oversubscribed $4.5 million.

"This investment will help us accelerate development and integrations to create additional visibility across the varied technology stacks that MSPs [or, managed service provider] support," says Alapat in a release. "Our true goal is to support MSPs across the entire client journey — automating onboarding, documentation, and insight that speeds up issue resolution — unleashing teams to operate at 10X." Read the full story here.

Marissa Limsiaco, CEO of Tenavox

This month, InnovationMap is profiling the faces of Pride within innovation. Marissa Limsiaco, CEO of Tenavox, discusses her career and the company's expansion plans. Courtesy of Tenavox

Though Marissa Limsiaco actually resides down Highway 290 in Austin, her company, Tenavox, has some of its operations here. The commercial real estate-finding tech tool is growing, and Limsiaco is among the ones to credit for Tenavox's success. She discussed the growth plans — including the plan to enter the Dallas market by the end of the year — in a special Pride Month series. Read the Q&A here.

Ryan Schwartz, CEO and founder of Mental Health Match

Ryan Schwartz realized online dating was easier than finding a therapist. He created a tool to change that. Courtesy of Mental Health Match

When you're in great need for a therapist, the worst thing you have to do go through the process to actually find someone you can count on. It's a tiring process to discover a new therapist who meshes well with you and has the capabilities for what you need. Ryan Schwartz created Mental Health Match to pair up patient to professional — and it's designed to be free for those who need it most: The patient. Check out the story here.


This month, InnovationMap is profiling the faces of Pride within innovation. Marissa Limsiaco, CEO of Tenavox, discusses her career and the company's expansion plans. Courtesy of Tenavox

Tenavox leader on expanding in Texas and LGBTQ representation within innovation

Featured innovator

After founding her second startup, Marissa Limsiaco thought that would be her last.

But years later, Limsiaco, a U.S. Army veteran with three degrees under her belt, was pulled back into the entrepreneurship world by Tenavox, a commercial real estate leasing company that gives tenants negotiating power through an online platform that shares space requirements, location and an expected price for the unit.

This month, InnovationMap is profiling the faces of Pride within Houston innovation. Limsiaco spoke with InnovationMap about her career, Tenavox, and the importance of the LGBTQ community in entrepreneurship.

InnovationMap: What has happened with Tenavox in the last eight months since InnovationMap has spoken with you?

Marissa Limsiaco: Oh gosh, it has felt like years. In the startup world, eight months is like two years and three months is like a year it feels. (Back in November), we were just launching our sales efforts.

Since last year going into this year, our (monthly recurring revenue) has grown over 100 percent. We've now connected tenants to agents and generated over $3.5 million in deals. So that's been really exciting that we're making those connections. And now most recently, we've closed a round this month. We are kind of focusing on a new offering called Tour Ready that we're selling to customers are on the project leasing side. Ultimately, it allows people who are looking for space to see and book a tour in a matter of minutes if it feeds their needs.

IM: I know that you took your service in the military and used that experience with leadership and management to become a successful entrepreneur. You have been a part of different startups in addition to Tenavox. Could you have imagined yourself at this point in your career 5 to 10 years ago?

ML: Absolutely not. I would not have even thought this was an option 5 or 6 years ago. Even though I was out of the Army, I was still learning business and going through that transition. After that second business that I started I told myself "I'm never going to do this again," and now I'm on my fourth.

IM: What compelled you to keep going in the startup world?

ML: It was this opportunity and the impact that we can have on everybody that we're helping on this platform, from business owners all the way to commercial agents and ownership groups. As a business owner myself, I experience the struggle firsthand of finding space and how frustrating that was. And it's sad that in 2019, one of the most effective ways to find spaces is driving around, calling signs with little to no information. When I saw how big the problem was and how antiquated the industry is where nothing has changed as far as making it any better for people to search for space to lease, I was just super determined to solve this problem.

IM: The last time InnovationMap spoke to you, Tenavox had just received funding from RealCo, an accelerator program funded by Geekdom fund. What has that funding been used for?

ML: Oh, yeah, we've raised more funding since then. And we have enough money now to go to the rest of Texas, which is exciting.

IM: When are the expansions?

ML: Well right now, we're in Houston and Austin and then we're going to go to Dallas towards the end of this year. We are also going to raise a round to go out of Texas. Josh [Feinberg, my co-founder,] and I have a larger vision vision for Tenavox and we really want to take it national. So we're going to prepare toward the end of this year, and next year we're going to open up on a bigger round of fundraising to be able to go to other states.

IM: What are some of the ways the tech and innovation community support their LGBTQ colleagues throughout the month of June?

ML: Expanding to other industries and awareness of minorities in other industries, whether it be LGBTQ or women, I think highlighting folks that are in those groups that are in the industry helps a lot. Two years ago when I became CEO and we started this company, it was daunting and scary. There's not a lot of women doing what I do, right? Something that keeps me going is that I have to show another girl or whoever that it's possible to be in my position.

IM: What advice would you have for a young gay or lesbian entrepreneur heading into the military or tech and real estate industries?

ML: Don't be scared to do things that you're scared of. I know everybody's different but the times I found myself in positions like I am today was because I was scared of it. I was scared of what happened, but I knew that I had to do it to overcome it or to see what would happen. The last industry in this whole entire world ever that I would have thought about five years ago would be commercial real estate. And yet when the opportunity presented itself, I just went for it. I just knew that I was going to grow and because I challenged myself and whenever I've faced that, I've come out totally another person, especially just me personally in this role. I tell a lot of the young people that I mentor that if an opportunity presents itself and it may not interest you, you should still look into because you just never know.

IM: What does Pride Month mean to you?

ML: It means empowering the LGBTQ community. The importance of having a whole month in this year that is dedicated to reminding everybody — and it even extends beyond LGBTQ — that you should just be who you are. Be proud of who you are. And I think that means a lot.

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Portions of this interview have been edited.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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