3 Houston innovators to know this week

Who's Who

These three movers and shakers in innovation are ones to know going into this week. Courtesy photos

This week's Houston innovators to know covers all the bases, from a freshly started startup to one that closed a multimillion-dollar raise. Here's who in Houston innovation that you need to know.

Joe Alapat, CEO of Liongard

Houston-based Liongard has fresh funds thanks to a $4.5 million round. Courtesy of Liongard

Joe Alapat has something to celebrate. His Houston-based startup, Liongard — an Information Technology automation and management company — closed its Series A round of funding with an oversubscribed $4.5 million.

"This investment will help us accelerate development and integrations to create additional visibility across the varied technology stacks that MSPs [or, managed service provider] support," says Alapat in a release. "Our true goal is to support MSPs across the entire client journey — automating onboarding, documentation, and insight that speeds up issue resolution — unleashing teams to operate at 10X." Read the full story here.

Marissa Limsiaco, CEO of Tenavox

This month, InnovationMap is profiling the faces of Pride within innovation. Marissa Limsiaco, CEO of Tenavox, discusses her career and the company's expansion plans. Courtesy of Tenavox

Though Marissa Limsiaco actually resides down Highway 290 in Austin, her company, Tenavox, has some of its operations here. The commercial real estate-finding tech tool is growing, and Limsiaco is among the ones to credit for Tenavox's success. She discussed the growth plans — including the plan to enter the Dallas market by the end of the year — in a special Pride Month series. Read the Q&A here.

Ryan Schwartz, CEO and founder of Mental Health Match

Ryan Schwartz realized online dating was easier than finding a therapist. He created a tool to change that. Courtesy of Mental Health Match

When you're in great need for a therapist, the worst thing you have to do go through the process to actually find someone you can count on. It's a tiring process to discover a new therapist who meshes well with you and has the capabilities for what you need. Ryan Schwartz created Mental Health Match to pair up patient to professional — and it's designed to be free for those who need it most: The patient. Check out the story here.


This month, InnovationMap is profiling the faces of Pride within innovation. Marissa Limsiaco, CEO of Tenavox, discusses her career and the company's expansion plans. Courtesy of Tenavox

Tenavox leader on expanding in Texas and LGBTQ representation within innovation

Featured innovator

After founding her second startup, Marissa Limsiaco thought that would be her last.

But years later, Limsiaco, a U.S. Army veteran with three degrees under her belt, was pulled back into the entrepreneurship world by Tenavox, a commercial real estate leasing company that gives tenants negotiating power through an online platform that shares space requirements, location and an expected price for the unit.

This month, InnovationMap is profiling the faces of Pride within Houston innovation. Limsiaco spoke with InnovationMap about her career, Tenavox, and the importance of the LGBTQ community in entrepreneurship.

InnovationMap: What has happened with Tenavox in the last eight months since InnovationMap has spoken with you?

Marissa Limsiaco: Oh gosh, it has felt like years. In the startup world, eight months is like two years and three months is like a year it feels. (Back in November), we were just launching our sales efforts.

Since last year going into this year, our (monthly recurring revenue) has grown over 100 percent. We've now connected tenants to agents and generated over $3.5 million in deals. So that's been really exciting that we're making those connections. And now most recently, we've closed a round this month. We are kind of focusing on a new offering called Tour Ready that we're selling to customers are on the project leasing side. Ultimately, it allows people who are looking for space to see and book a tour in a matter of minutes if it feeds their needs.

IM: I know that you took your service in the military and used that experience with leadership and management to become a successful entrepreneur. You have been a part of different startups in addition to Tenavox. Could you have imagined yourself at this point in your career 5 to 10 years ago?

ML: Absolutely not. I would not have even thought this was an option 5 or 6 years ago. Even though I was out of the Army, I was still learning business and going through that transition. After that second business that I started I told myself "I'm never going to do this again," and now I'm on my fourth.

IM: What compelled you to keep going in the startup world?

ML: It was this opportunity and the impact that we can have on everybody that we're helping on this platform, from business owners all the way to commercial agents and ownership groups. As a business owner myself, I experience the struggle firsthand of finding space and how frustrating that was. And it's sad that in 2019, one of the most effective ways to find spaces is driving around, calling signs with little to no information. When I saw how big the problem was and how antiquated the industry is where nothing has changed as far as making it any better for people to search for space to lease, I was just super determined to solve this problem.

IM: The last time InnovationMap spoke to you, Tenavox had just received funding from RealCo, an accelerator program funded by Geekdom fund. What has that funding been used for?

ML: Oh, yeah, we've raised more funding since then. And we have enough money now to go to the rest of Texas, which is exciting.

IM: When are the expansions?

ML: Well right now, we're in Houston and Austin and then we're going to go to Dallas towards the end of this year. We are also going to raise a round to go out of Texas. Josh [Feinberg, my co-founder,] and I have a larger vision vision for Tenavox and we really want to take it national. So we're going to prepare toward the end of this year, and next year we're going to open up on a bigger round of fundraising to be able to go to other states.

IM: What are some of the ways the tech and innovation community support their LGBTQ colleagues throughout the month of June?

ML: Expanding to other industries and awareness of minorities in other industries, whether it be LGBTQ or women, I think highlighting folks that are in those groups that are in the industry helps a lot. Two years ago when I became CEO and we started this company, it was daunting and scary. There's not a lot of women doing what I do, right? Something that keeps me going is that I have to show another girl or whoever that it's possible to be in my position.

IM: What advice would you have for a young gay or lesbian entrepreneur heading into the military or tech and real estate industries?

ML: Don't be scared to do things that you're scared of. I know everybody's different but the times I found myself in positions like I am today was because I was scared of it. I was scared of what happened, but I knew that I had to do it to overcome it or to see what would happen. The last industry in this whole entire world ever that I would have thought about five years ago would be commercial real estate. And yet when the opportunity presented itself, I just went for it. I just knew that I was going to grow and because I challenged myself and whenever I've faced that, I've come out totally another person, especially just me personally in this role. I tell a lot of the young people that I mentor that if an opportunity presents itself and it may not interest you, you should still look into because you just never know.

IM: What does Pride Month mean to you?

ML: It means empowering the LGBTQ community. The importance of having a whole month in this year that is dedicated to reminding everybody — and it even extends beyond LGBTQ — that you should just be who you are. Be proud of who you are. And I think that means a lot.

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Portions of this interview have been edited.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

5 must-read innovation headlines: Pharma giant considers Houston hub + more

Trending news

Editor's note: With May coming to a close, it's time to look back at the biggest innovation headlines for the second half of the month. Major moves were made in May, with NuScale Power entering the market, Persona AI inking a deal with Under Armour, and a pharma giant considering Houston for its next manufacturing hub. Here are the most-read InnovationMap stories published May 15-29, 2026:

1. Pharma giant considers Houston for $1 billion manufacturing campus

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub. According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

2. Modular nuclear reactor co. NuScale Power moves into Houston market

The nuclear energy renaissance continues in Texas with an announcement by NuScale Power. The Oregon-based provider of proprietary and innovative advanced small modular reactor (SMR) nuclear technology announced in April it would be opening office space in Houston’s CityCentre.

3. Persona AI teams with Under Armour to protect next-gen robots

Houston-based Persona AI has cemented a partnership with sportswear manufacturer Under Armour to provide materials to protect future robots operating in dangerous conditions. Through the partnership, Persona AI and Under Armour will launch a research initiative to explore whether advanced performance textiles can improve the durability and resilience of humanoid robots operating in harsh industrial environments.

4. Houston quantum energy chip startup emerges from stealth with $12M round

Houston-based Casimir has emerged from stealth with a $12 million seed round to commercialize its quantum energy chip. The round was led by Austin-based Scout Ventures. Lavrock Ventures, Cottonwood Technology, Capital Factory, American Deep Tech, and Tim Draper of Draper Associates also participated in the round. The oversubscribed round exceeded the company’s original $8 million target.

5. Global summit spotlights Houston's growing role in brain health, innovation

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. The summit, held June 9-10 at the Texas Medical Center's Helix Park, will bring together more than 500 executives, researchers, policymakers and innovators from around the world to discuss the global brain economy.

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”

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