3 Houston innovators to know this week

Who's who

In honor of Labor Day, here are three Houston innovators who probably aren't taking the day off. Courtesy photos

It may be Labor Day, but some of the hardest working Houston innovators are probably still checking their email on their phones from the pool.

Here are this week's innovators to know around town.

Marie Myers, CFO of UiPath

Marie Myers is the CFO of UiPath. Courtesy of UiPath

Marie Myers is a self-proclaimed Houstonian, avid bike rider, and robotics nerd — for lack of a better word. She's had a 20-year career in tech — most roles based right here in town — and throughout her whole experience, robotics process automation has been the most exciting technology she's gotten to work with.

UiPath just opened an office in Houston earlier this year, and Myers serves the company as CFO. She first worked with UiPath on the client side of things, and the technology awed her. She says she jumped at the opportunity to join the organization.

"When I think about RPA, the world lights up for me," she says. "It's truly transformative."

Click here to read more about the company.

Marco Bo Hansen, chief customer officer at Sani nudge and his executive team

Marco Bo Hansen, right, the chief customer officer at Sani nudge. Courtesy of TMCx

The Sani nudge executives may not be from Houston, but we give the Denmark-based company a pass for all its success coming out of the Texas Medical Center's accelerator program earlier this year. Sani nudge is a medical device company that can better track and encourage hand sanitation. The company is headed to California after being selected for a prestigious program with the Mistletoe Foundation.

Dr. Marco Bo Hansen is the chief customer officer and says that he'll be vigilantly advocating that his Sani nudge colleagues and the Mistletoe researchers keep hospital patients and staff in mind as Sani nudge moves forward with its innovations.

"We have to make sure that our solutions always generate value to the end users and can easily be used by the clinicians, infection preventionists, and hospital managers," he says.

Click here to read more about the company.

Ashley Gilmore, CEO and co-founder of Tracts.co

When Ashley Gilmore was studying law — specifically for the purposes of going into oil and gas — it amazed him how non-digitized the industry was, especially the mineral buying process. Gilmore figured out a way how to use tech to make the process way easier — and cheaper.

Now, his company, Tracts, has a new land group that's growing at a revenue rate of 30 percent month to month. With more and more clients, Tracts engages more data. And, with more and more data, the product increases in value for his customers.

"For some of our clients, Tracts is now existential for their business," Gilmore says. "In other words, they wouldn't be able to operate on their current business model without Tracts."

Click here to read more about the company.

Marie Myers is the CFO of UiPath and is based in the company's new Houston office. Courtesy of UiPath

Robotics exec talks plans for new Houston office and the future of automation

robot revolution

It's safe to say that Marie Myers — CFO of UiPath, which opened its 71-person office in Houston earlier this year — loves her job.

The robotics process automation company, which was founded in Romania before moving its headquarters to New York City last year, is in major growth mode. At the helm of the financial side of things is Myers, who has over 20 years of experience in technology.

When Myers was working on a spinoff project for HP, she started seeing the difference software automation makes on a company's bottom line.

"I realized RPA was the fastest way to drive efficiencies, so I started building bots," she tells InnovationMap. "During that time, I came across UiPath and I saw how impressive their technology was. In my more than two-decade career, I hadn't really come across a technology that I felt that had such an impressive impact in such a short time."

She drank the UiPath Kool-Aid, and when the company came to her adopted hometown of Houston to open an office to be its central, Midwestern location, she leapt at the opportunity to join the team. Now, with several months under her belt in the position and a growing office, Myers speaks with InnovationMap about the company's growth and the revolution that RPA is having in business.

InnovationMap: You've been in your role since January, but you've been in tech for a while now. How has the transition been for you?

Marie Myers: This has been one of the most exciting times for my career. I've been in tech for about two decades. I started with Compaq — quite an incredible company that started right here in Texas. It was a very famous startup in its own time, and I had a chance to be a part of that wave, which was really incredible. Then, it got bought out by HP, and then I pivoted and spent a lot of time in Silicon Valley for a couple decades.

I got involved in robotics process automation quite by happenstance about four years ago when HP decided to split. I was involved in setting up a company from the finance and legal perspective. I got challenged to drive some cost efficiency, so I turned to RPA as a means to drive some of that impact within my own organization of a couple thousand folks.

When the opportunity came up to be CFO for UiPath, I really jumped at it because it filled two important things for me. I wanted to be a leader of a finance organization and team. Secondly, I wanted to do something where I was really passionate about the technology. When I think about RPA, the world lights up for me. It's truly transformative.

IM: How did UiPath decide to open a Houston office? What made the city a key market?

MM: Houston — particularly Texas — are both important for us, from a customer perspective. We have some of our larger companies in the country here in Texas, so it was a natural place to look to build capability. Secondly, we're impressed with the overall quality of the market and the availability of different skills here as we build out our company.

IM: What are some goals UiPath has for its new Houston office?

MM: Overall, one of the key goals is to establish a strong Midwest presence for the company. Texas is an ideal location if you think about it for customers that range from the East to the West. Being in the middle is a good, central location. Also, as we grow and expand in Latin America, it's another interesting spot for us. So, one, to ensure that we are able to support the growth needs of the company throughout the United States and leverage the strategic location that Texas has.

I think the other goal is to build some of the core skills we need for the overall organization as we grow in the United States. UiPath is a relatively new player in the U.S., only been here a couple of years.

Finally, we've got terrific customers here, so what's important is to continue to support and nurture those customers. We have a big presence in oil and gas and the support companies within energy.

IM: Tell me about the Academic Alliance and how the company engages with students.

MM: Basically, we offer free training to the universities so that students can get first-hand experience for robotics process automation, which is part of our broader commitment we've made to ensure RBA is available in an open, democratized way.

We are big proponents of supporting students, and we had a great intern program this last summer. We had a double-digit number of interns — I think the largest population in the U.S. We love the fact that we have this access to universities that we can easily tap into.

Just a couple weeks ago we ran UiPath's first-ever hackathon for students in the United States. We had over 50 participants.

We're really excited about building out the ecosystem with the universities and the students here in Houston.

IM: What sort of misconceptions do you encounter within automation?

MM: First and foremost, a lot of it is misconceptions about RPA replacing jobs. I'd say it's a shift in the workforce — I witness this first hand because I had a team where we implemented and built bots. What happens is you create capacity and end up creating new jobs. You have roles of managing bots, bot controllers, bot librarians — these are roles that fundamentally didn't exist five years ago.

IM: What advice do you have for women in tech?

MM: I think it's so critical for women to be in the driving seat and in the forefront of technology. I have two daughters and I'm adamant about how they are exposed to robotics. I did a coffee talk in Houston not too long ago, and I really challenged the women to get out there and get digitally literate. It's really important as women that we don't let ourselves fall behind on technology and how they are impacting both our work and our families. So, staying informed, no matter how you do that — reading, podcasts, news. Another way is to join and network with associations. Myself and another woman important in this space are looking to create a network for women in automation. We want to build a group that will allow women to look for jobs, board roles, mentors, etc. in this industry.

IM: What role do you see Houston playing in the greater innovation conversation and where does the city have room to improve?

MM: I'm a big fan of Houston. I'm Australian, but I feel like a Texas implant now. It's an incredibly diverse city, and I think that's one of its greatest strengths. You've got people from all walks of life from all parts of the world and a great education system. That creates a really unique backdrop for the technology-led era we're in. The historical strengths of the city have been predicated on the healthy oil and gas sector and medical sector — both are important industries going through major technology transformations. I think for Houston being able to capitalize on all that is a very unique opportunity. It will position Houston very well for the future. You've got the right ingredients here.

Where the city is going to have to continue to build is specifically around some of these skills for the future. Artificial intelligence and having that depth of experience is an area the city struggles in. Certainly other cities like Seattle and San Francisco have tens of years of experience from companies like Google, Facebook, and Amazon that have been able to build deep AI. In Houston, that skillset is going to come more from oil and gas, where they've been building some of those skills, just not in the same breath and not in the same depth as those other cities. I think the real opportunity is to nourish and nurture this in the academic institutions and then take that talent out of the academic institutions and integrate them into the corporations.

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Portions of this interview have been edited.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

$1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
$922 million for the University of Houston System
$167 million for Texas Southern University
$10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
Created the Lake Houston Dredging and Maintenance District
Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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