When examining how you can better prepare and respond to ongoing climate-related challenges, the CRE community needs to prioritize marginalized communities that are already experiencing most of the negative impacts. Photography by Peter Molick

Houston is no stranger to hurricanes, and in recent years winter storms have become an increasing concern. Following the winter freeze in 2021, more than 4 million Texans were left without power, water, or heat. The state’s infrastructure system was adversely impacted concurrently — including workplaces, hospitals, transportation, homes, drinking water distribution, electric power generation, agriculture, and grocery stores. Now, a new potential disaster is on the horizon. Recent research shows Houston is most likely to be affected by wildfires, a climate-related challenge that our city has not previously faced.

According to the Gensler Research Institute’s 2022 U.S. Climate Action Survey, since 2019, only 18 percent of Americans believe their communities are built to withstand climate change. The good news is Americans overwhelmingly agree that addressing climate change is urgent. The question many are asking is — “How can we take action to better prepare buildings and cities to weather the climate challenge?” The solution is simple. In order to understand where we need to go, we must understand how we got here.

With a population that has more than doubled in the past 50 years, it is challenging for most Houstonians to imagine a time when The Bayou City was nothing more than agricultural lands and oil fields. Today, Houston is known for being the fourth-most populous city in the United States. It is a sprawling concrete jungle home to the world’s largest concentration of healthcare and research institutions. When reflecting on the past 50 years, one can’t help but evaluate the city’s successes and shortcomings. While Houston has succeeded in becoming a diverse, international city, we have sacrificed the very ecology that once made up one of the country’s most productive agricultural areas. By 1980, Houston possessed the least amount of green space per person in the country.

As new developments popped up across the city, it became difficult to convince developers to pursue third-party certifications such as LEED, a globally recognized symbol of sustainability that provides the framework for designing healthy, efficient, carbon saving buildings. We can credit Hines with being one of the few developers in Houston to prioritize green design during the early-2000s. City leaders also began advocating for resilient strategies and more green space to attract and retain international talent and businesses. In recent years, we have seen an increase in buildings that are achieving LEED certification, and soon it will become the baseline.

The Houston Advanced Research Center, Photography by Shau Lin Hon, Slyworks Photography

An example of a project leading the way for resilient design is The Houston Advanced Research Center (HARC). In 2017 the organization completed work on its LEED Platinum Certified headquarters which was designed to meet the ENERGY STAR certification rate of 99 (out of 100). This means that the building is more efficient than 99 percent of all office buildings in the United States. Skanska is another construction and development company bringing a sustainable mindset to downtown Houston with its work on Bank of America Tower. In 2019, the 775,000 square foot building became the largest LEED v4 Platinum Core and Shell certified project in the world to date and was developed with harvesting technology that will significantly reduce energy usage.

It’s also important to understand the impact that the climate crisis is having on people. 91 percent of U.S. Gen Z/Millennials have been affected by extreme weather events since 2019, the most of any generation. These experiences have resulted in two generations preparing to react and combat climate change and has encouraged a spirit of transparency among companies who choose to share their environmental goals and strategies.

For architects and designers, addressing building and energy codes is proving to be the next big design consideration. As codes progress in the coming years, the result will be more unique and unexpected building designs.

When reimagining the use of buildings, Architects Paulina Abella and Tayler Trojcak propose an experimental process for repurposing vacant buildings called High Hackers. The concept provides an opportunity for developers to offer prime downtown real estate to people with diverse skill sets, whom they call “hackers,” to pursue projects shaped by their individual ideas. These hackers—makers, artists, and academics—will work alongside one another in spaces that encourage them to coexist with creatives from other fields and disciplines. More importantly, it fosters a collaborative, organic, and innovative workflow.

When examining how you can better prepare and respond to ongoing climate-related challenges, we encourage prioritizing marginalized communities that are already experiencing most of the negative impacts. Promoting awareness and optimism in our communities is another simple yet effective way to make a difference. For businesses, creating a sense of continuity in the face of climate events, investing in energy and resource efficiency and adaptation, and addressing insurability and the long-term value of real estate will ultimately help lead Houston and its community members toward a place of preparedness and resiliency.

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Rives Taylor directs Gensler’s Global Design Resilience teams and initiatives and has been a faculty member of both Rice University and the University of Houston for 30 years. Maria Perez is a design resilience leader for Gensler’s South Central region and director of sustainable design based in Gensler’s Houston office.

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CultureMap Emails are Awesome

7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”