Across industries, these three founders found a new way of doing things. Images courtesy

This week's innovators to know truly represent the spirit of innovation. All three looked at a traditional way of doing something, and reimagined it — from design to smart technology.

Andre Norman, founder of Jellifin

Andre Norman founded Jellifin, an options trading platform, flipping the script on the traditional investment process. Courtesy Jellfin

When it comes to investing in stock options, you might go the traditional route and seek out a brokerage that focuses on options trading. There's a major catch, though: most brokerages tack on a fee of anywhere between $7 and $20 per trade, says Andre Norman, founder of Jellifin, an online options trading platform, is disrupting that norm.

The company works with individuals and brokers to provide an options trading platform at a flat monthly fee. This allows investors to trade as frequently or infrequently as they please, and to not factor in the cost of a trade fee when considering what's best for their portfolio.

"A lot of people don't invest because of the high costs associated with trading," Norman said. "We allow them to get into investing without having to pay huge amounts of money."

Read more about Jellifin and its founder here.

Lisa Pope Westerman, founder and CEO of LUCID

Lisa Pope Westerman has created LUCID, a network of architects that's flipping the script on how architecture projects go. Courtesy of LUCID

When it comes to the traditional method of design integration, Lisa Pope Westerman saw a disconnect. She created LUCID, a collective of architects and boutique architecture firms, to help connect the dots within the industry. When clients retain LUCID as their designer or architect, they're given access to the firms and individual architects who are best suited for the job.

"People have referred to us as 'the WeWork of architecture,' or 'the Uber of design,'" Pope Westerman says. "We think that in 10 years, this is how the world will just be working."

Read more about LUCID and its founder here.

Marci Corry, owner of SAFE 2 SAVE

Marci Corry had the idea for SAFE 2 SAVE in 2016 when she met with a college student she was mentoring to discuss how to help the student's peers detach from their phones. They agreed that incentives, particularly food, were the key, and not just for college kids. Now, the Houston-based app has blown up to include a fan base of more than 148,000 users, 20 employees, and a partnership with Memorial Hermann.

"They said, 'We want this to stop happening. We don't want these people being pushed through our door on a stretcher and this is epidemic in Houston,'" Corry says.

Read more about SAFE 2 SAVE and its founder here.

Lisa Pope Westerman has created LUCID, a network of architects that's flipping the script on how architecture projects go. Courtesy of LUCID

Meet the Houston entrepreneur behind the 'Uber of design'

Featured Innovator

What if retaining one architecture company gave you access to dozens more? That's the idea behind LUCID, an architecture and design collective that Lisa Pope Westerman, formerly of San Francisco-based Gensler and New York City-based rockwell group, launched in Houston this year.

LUCID is a collective of architects and boutique architecture firms that specialize in at least one of the following property types: hospitality, retail, mixed-use developments, high-rise residential, and wellness developments. When clients retain LUCID as their designer or architect, they're given access to the firms and individual architects who are best suited for the job. Currently, LUCID is composed of roughly 40 total architects coming from several architecture and design firms, including Chicago-based PinPoint Collective, Houston-based gin design group, and New York-based Glen & Co. architecture.

"People have referred to us as 'the WeWork of architecture,' or 'the Uber of design,'" Pope Westerman says. "We think that in 10 years, this is how the world will just be working."

Pope Westerman spoke with InnovationMap about launching LUCID, Houston's unique design community and how the architecture industry continues to innovate.

InnovationMap: When did you start planning LUCID?

Lisa Pope Westerman: I really started thinking about it in beginning of 2018, and working on it middle of 2018, and making sure the initial groups we started with are a good fit. It's been nothing but wonderful. Everyone's smarter than me, and brings such a unique perspective to the group for various reasons. Not everyone is an architect or an interior designer ­– the intent is to be really nimble and flexible. We're bringing a lot of unique specialists. We have branding, graphic design, and a strategy group that is just amazing.

We're looking to, as a group, not just be innovative, but have innovation in all the different types of things [we offer], including our process. We believe that the world of design is going to be much more than visual, and that we really need to be thinking about all the senses, like touch and smell and [hearing]. Just typically, everything's visual, and [the other senses] have been secondary.

IM: How did LUCID find the architects and architecture firms that compose the collective?

LPW: The original of roughly 40 people are people I've worked with over the past 20 years. That's how we got things started. I've basically been involved in every size company imaginable: from a one-man show, to the largest design firm in the world, Gensler. The intent of the model is to create something where there's a parent brand that feels like a very large company, and we're essentially an umbrella, and within us are all the other wonderful boutique specialty brands.

IM: What kinds of architecture firms does LUCID work with?

LPW: Most of the firms affiliated with us are around a dozen people. We find that's the right size of people that are highly specialized, super talented, and able to maintain the [high] quality level.

IM: Tell me a bit about LUCID's business model.

LPW: So, we facilitate everything, and that's how [LUCID] is compensated. So, we essentially facilitate in bringing the companies to the client, which is the business development aspect of things. We collaborate on the client management side, so we're still very involved with the clients and the projects. We carry everybody. We help manage all of it, and all of the companies' [projects]. It's a true collaboration.

People truly believe that by being associated with LUCID, they're going to be able to elevate what they've been doing even more. It's important that the companies that want to be affiliated with LUCID are really interested in that.

IM: Can the architecture firms that are a part of LUCID still do work outside of the LUCID collective?

LPW: All the firms connected to LUCID still do their own business. They haven't folded into LUCID and then given up their brand. The intent is that we're celebrating the brands. We like the diversity.

IM: LUCID is currently working on its first project. What information can you share?

LPW: It's in the hospitality industry, and it is a restaurant, bar, event space, and it's for a private club outside of Houston. We started at the beginning of [2019], and we'll be done at the end of the year.

IM: Did LUCID launch with a fund raise? Are you planning a fund raise?

LPW: The front end is really just a shared passion among the companies and individuals that are connected. Longer term, we are interested in even partnering with investors in creating new and different kinds of projects. There are some other firms out there, but not many, that are starting to do that sort of thing … where [the design firm] collaborates with investors and projects, rather than just being hired on as the designer for a project.

IM: How is the Houston design scene different from design scenes around the world?

LPW: Well, I think it's an exciting time for Houston. Especially in our world of lifestyle design, it's the overarching [theme]. We do everything for lifestyle. In Houston, we're really starting to be at the height of this renaissance of bringing just a higher level of appreciation for design. From a lifestyle standpoint, things have been percolating for a while now.

IM: What's a foundational project you've worked on that taught you an essential lesson about design?

LPW: In terms of my Houston project base, certainly the ExxonMobil project was really impactful, because of the scale of the project and all the different participants in it. We collaborated with several other design firms, both in Houston and out of Houston, and not only design firms, but also globally acclaimed artisans. Just at a worldwide level, the caliber of the clients was amazing. It was an incredible experience because of the scale and the success of it. … It was building a city.

------

Portions of this interview have been edited.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”