California energy storage startup doubles down on Houston with larger space, growing team

betting on HOU

Plus Power, which recently relocated its HQ to Houston, has moved into a larger office space. Image via cushmanwakefield.com

A Northern California-born energy storage startup has established its headquarters in The Woodlands.

Plus Power, which develops battery systems designed to store backup power for electric grids, recently signed a lease for nearly 7,000 square feet at Three Hughes Landing in The Woodlands. The company previously was based in coworking space at the Rayford Office Park in Spring.

The company, founded in 2018, shifted its headquarters from San Francisco to the Houston area last year.

“We chose The Woodlands for its beauty, and walkable access to great nearby hotels, restaurants, and healthy groceries,” says Brandon Keefe, CEO of Plus Power. “A Houston base reflects our deep focus on the Texas market, as we are investing nearly $1 billion in several projects here that will be online by the first quarter of 2024, with more in [the works] behind that.”

About 40 employees work from Plus Power’s new office in The Woodlands. Across North America, the company employs about 130 people, including several in Austin. As of July 10, the startup listed nine job openings.

Plus Power develops, owns, and operates utility-scale systems that store energy in huge lithium-ion batteries during low-demand periods. In times of peak demand, power providers can tap into this stored energy.

“Standalone energy storage is rapidly transforming the U.S. energy markets, because it is cheaper than new natural gas plants, faster to build than fossil peakers or transmission, and able to perform diverse energy services,” the company explains in its job postings.

Peakers are backup power plants that run on fossil fuels.

One of Plus Power’s storage facilities is the 100-megawatt Gambit project, which opened two years ago in Angleton. The nearly eight-acre facility supports power supplies for the Electric Reliability Council of Texas (ERCOT), which runs the power grid for 90 percent of Texas.

The company says the Angleton facility has fed backup energy to ERCOT during this year’s and last year’s heatwaves, as well as last December’s winter freeze.

The Gambit facility might ring a bell with some folks in the Houston area. In January 2022, Austin-based automaker Tesla unveiled a backup power storage facility in Angleton. Plus Power bought the project from Tesla in June 2022.

Plus Power’s development pipeline contains 10 gigawatts’ worth of energy storage projects in 28 states and Canada. That includes massive projects on tap for Hawaii and Arizona.

Last November, Plus Power announced it had secured $219 million in debt financing for construction of the 185-megawatt Kapolei project on a roughly eight-acre site in Oahu, Hawaii. The facility will be tied to Hawaiian Electric’s power grid. Mizuho Securities USA and KeyBank led the financing.

This April, Plus Power held a groundbreaking ceremony for the Sierra Estrella project in Tolleson, a Phoenix suburb. The 250-megawatt system will serve Salt River Project (SRP), a utility provider in the Phoenix area. The roughly 11-acre Tolleson facility is set to open next year, as is another Plus Power project for SRP — the 90-megawatt Superstition facility in Gilbert, another Phoenix suburb.

As its development pipeline demonstrates, Plus Power is firmly plugged into the fast-growing energy storage market.

According to the Houston-based energy research and consulting firm Wood Mackenzie and the American Clean Power Association, the U.S. energy storage market installed a record-breaking 4.8 gigawatts of capacity in 2022. This year, that number is projected to approach 75 gigawatts.

In a March 2023 news release, John Hensley, the clean power group’s vice president of research and analytics, says the U.S. market “is on a rapid growth curve and is already a key component of building a resilient grid that supports abundant clean energy.”

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This article originally ran on EnergyCapital.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

New accelerator joins the Ion and more Houston innovation news to know

Trending News

Editor's note: The Houston innovation scene is buzzing with big news this month, from a new accelerator joining the fold at the Ion to pre-IPO funding and national expansion plans. Below are the five most-read InnovationMap stories from Feb. 1-15, 2026:

New accelerator for AI startups to launch at Houston's Ion this spring

The new AI Native Dual-Use Sports, Health & Wellness Accelerator is expected to launch in March. Photo courtesy of the Ion

The Collectiv Foundation and Rice University have established a sports, health and wellness startup accelerator at the Ion District’s Collectiv, a sports-focused venture capital platform. The AI Native Dual-Use Sports, Health & Wellness Accelerator is scheduled to formally launch in March. Continue reading.

10+ can't-miss Houston business and innovation events in February

From recurring monthly favorites to the return of annual celebrations and summits, here's what not to miss in February. Photo courtesy the Ion.

February may be a short month, but its event calendar isn’t. From recurring monthly favorites to the return of annual celebrations and summits, here are the Houston business and innovation events not to miss — and how to register. Continue reading.

Houston lab-test startup seeks $1M for nationwide expansion

Jim Gebhart, founder and CEO of TheLabCafe.com. Courtesy photo.

Health care industry veteran Jim Gebhart knew there had to be a better way for patients to access lab services, especially those with high health insurance deductibles or no insurance at all. Continue reading.

Houston wearable biosensing company closes $13M pre-IPO round

Wellysis is known for its continuous ECG/EKG monitor with AI reporting, known as the S-Patch. Photo via wellysis.com.

Wellysis, a Seoul, South Korea-headquartered wearable biosensing company with its U.S. subsidiary based in Houston, has closed a $13.5 million pre-IPO funding round and plans to expand its Texas operations. Continue reading. Continue reading.

Texas booms as No. 3 best state to start a business right now

Texas is rebounding in a report of the best states to start a business. Photo via Getty Images

High employment growth and advantageous entrepreneurship rates have led Texas into a triumphant No. 3 spot in WalletHub's ranking of "Best and Worst States to Start a Business" for 2026. Continue reading.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

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