The spacecraft reached an altitude of nearly 130 miles before landing in the Indian Ocean as planned. Photo via spacex.com

SpaceX’s mega Starship rocket completed its first full test flight Thursday, returning to Earth without exploding after blasting off from Texas.

It was the fourth launch of the world’s biggest and most powerful rocket, standing nearly 400 feet (121 meters) tall. The three previous flight demos ended in explosions. This time, the rocket and the spacecraft managed to splash down in a controlled fashion, making the hourlong flight the longest and most successful yet.

“Despite loss of many tiles and a damaged flap, Starship made it all the way to a soft landing in the ocean!” SpaceX CEO Elon Musk said via X.

Starship was empty as it soared above the Gulf of Mexico and headed east on a flight to the Indian Ocean. Within minutes, the first-stage booster separated from the spacecraft and splashed into the gulf precisely as planned, after firing its engines.

The spacecraft reached an altitude of nearly 130 miles (211 kilometers), traveling at more 16,000 mph (26,000 kph), before beginning its descent. Live views showed parts of the spacecraft breaking away during the intense heat of reentry, but a cracked camera lens obscured the images.

The spacecraft remained intact enough to transmit data all the way to its targeted splashdown site in the Indian Ocean.

It was a critical milestone in the company’s plan to eventually reuse the rocket that NASA and Musk are counting on to get humanity to the moon and then Mars.

“What a show it has been,” SpaceX launch commentator Kate Tice said from Mission Control at company headquarters in California.

SpaceX came close to avoiding explosions in March, but lost contact with the spacecraft as it careened out of space and blew up short of its goal. The booster also ruptured in flight, a quarter-mile above the gulf.

Last year’s two test flights ended in explosions shortly after blasting off from the southern tip of Texas near the Mexican border. The first one cratered the pad at Boca Chica Beach and hurled debris for thousands of feet (meters).

SpaceX upgraded the software and made some rocket-flyback changes to improve the odds. The Federal Aviation Administration signed off Tuesday on this fourth demo, saying all safety requirements had been met.

Starship is designed to be fully reusable. That’s why SpaceX wants to control the booster’s entry into the gulf and the spacecraft’s descent into the Indian Ocean — it’s intended as practice for planned future landings. Nothing is being recovered from Thursday’s flight.

NASA has ordered a pair of Starships for two moon-landing missions by astronauts, on tap for later this decade. Each moon crew will rely on NASA’s own rocket and capsule to leave Earth, but meet up with Starship in lunar orbit for the ride down to the surface.

SpaceX already is selling tourist trips around the moon. The first private lunar customer, a Japanese tycoon, pulled out of the trip with his entourage last week, citing the oft-delayed schedule.

SpaceX’s founder and CEO has grander plans: Musk envisions fleets of Starships launching people and the infrastructure necessary to build a city on Mars.

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

Launched from South Texas, SpaceX's Starship survived for around 50 minutes before losing contact and landing in the Indian Ocean. Photo via SpaceX/Twitter

SpaceX's mega rocket launch from Texas base provides mixed results

50-minute flight

SpaceX came close to completing an hourlong test flight of its mega rocket on its third try Thursday, but the spacecraft was lost as it descended back to Earth.

The company said it lost contact with Starship as it neared its goal, a splashdown in the Indian Ocean. The first-stage booster also ended up in pieces, breaking apart much earlier in the flight over the Gulf of Mexico after launching from the southern tip of Texas near the Mexican border.

“The ship has been lost. So no splashdown today,” said SpaceX’s Dan Huot. “But again, it’s incredible to see how much further we got this time around.”

Two test flights last year both ended in explosions minutes after liftoff. By surviving for close to 50 minutes this time, Thursday's effort was considered a win by not only SpaceX's Elon Musk, but NASA as well as Starship soared higher and farther than ever before. The space agency is counting on Starship to land its astronauts on the moon in another few years.

The nearly 400-foot (121-meter) Starship, the biggest and most powerful rocket ever built, headed out over the Gulf of Mexico after liftoff Thursday morning, flying east. Spectators crowded the nearby beaches in South Padre Island and Mexico.

A few minutes later, the booster separated seamlessly from the spaceship, but broke apart 1,500 feet (462 meters) above the gulf, instead of plummeting into the water intact. By then, the spacecraft was well to the east and continuing upward, with no people or satellites on board.

Starship reached an altitude of about 145 miles (233 kilometers) as it coasted across the Atlantic and South Africa, before approaching the Indian Ocean. But 49 minutes into the flight — with just 15 minutes remaining — all contact was lost and the spacecraft presumably broke apart.

At that point, it was 40 miles (65 kilometers) high and traveling around 16,000 mph (25,700 kph).

SpaceX's Elon Musk had just congratulated his team a little earlier. “SpaceX has come a long way,” he said via X, formerly called Twitter. The rocket company was founded exactly 22 years ago Thursday.

NASA watched with keen interest: The space agency needs Starship to succeed in order to land astronauts on the moon in the next two or so years. This new crop of moonwalkers — the first since last century’s Apollo program — will descend to the lunar surface in a Starship after transferring from NASA's Orion capsule in lunar orbit.

NASA Administrator Bill Nelson quickly congratulated SpaceX on what he called a successful test flight as part of the space agency's Artemis moon-landing program.

The stainless steel, bullet-shaped spacecraft launched atop a first-stage booster known as the Super Heavy. Both the booster and the spacecraft are designed to be reusable, although they were never meant to be salvaged Thursday.

On Starship’s inaugural launch last April, several of the booster’s 33 methane-fueled engines failed and the booster did not separate from the spacecraft, causing the entire vehicle to explode and crash into the gulf four minutes after liftoff.

SpaceX managed to double the length of the flight during November’s trial run. While all 33 engines fired and the booster peeled away as planned, the flight ended in a pair of explosions, first the booster and then the spacecraft.

The Federal Aviation Administration reviewed all the corrections made to Starship, before signing off on Thursday’s launch. The FAA said after the flight that it would again investigate what happened. As during the second flight, all 33 booster engines performed well during ascent, according to SpaceX.

Initially, SpaceX plans to use the mammoth rockets to launch the company’s Starlink internet satellites, as well as other spacecraft. Test pilots would follow to orbit, before the company flies wealthy clients around the moon and back. Musk considers the moon a stepping stone to Mars, his ultimate quest.

NASA is insisting that an empty Starship land successfully on the moon, before future moonwalkers climb aboard. The space agency is targeting the end of 2026 for the first moon landing crew under the Artemis program, named after the mythological twin sister of Apollo.

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CultureMap Emails are Awesome

7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”