Rice Alliance names 15 startups to its cleantech accelerator

ready to grow

Fifteen startups — with clean energy solutions involving everything from solar energy to hydrogen — are joining Rice Alliance's Clean Energy Accelerator later this summer. Photo via Getty Images

A clean energy program has announced its third cohort and named the 15 startups that were accepted into to the accelerator.

The Rice Alliance's Clean Energy Accelerator revealed its 2023 cohort that will be in the 10-week program that kicks of July 25. CEA, a hybrid program based out of the Ion, will wrap up with a Demo Day alongside the 20th Annual Rice Alliance Energy Tech Venture Forum on September 21.

The accelerator, led by Kerri Smith and Matt Peña, provides the cohort with programming, networking, and mentorship from six executives in residence — Nathan Ball, Fatimah Bello, Michael Egan, Michael Evans, Stephen Sims, and Deanna Zhang.

Since the Clean Energy Accelerator launched in 2021, the program has supported 29 ventures that have gone on to raise over $75 million in funding, identified and launched pilots, and created jobs, According to Rice, many of these companies relocated to Houston.

Class 3, which has already raised $23.3 million in funding, hails from four countries and seven states and are addressing a range of energy solutions — from advanced materials, carbon management/capture, energy storage, hydrogen, solar energy, wind energy, and more. They were selected by a screening committee consisting of more than 50 industry experts, investors, energy leaders, and entrepreneurs.

The third class, as announced by Rice Alliance, is as follows:

  • Ayrton Energy, based in Alberta, Canada, provides hydrogen storage technology that improves hydrogen transport logistics for distributed energy applications.
  • Headquartered in Massachusetts, Carbix transforms atmospheric carbon dioxide emissions into building materials using proprietary reactor technology.
  • Houston-based CryoDesalination lowers the carbon footprint and cost of removing salts and heavy metals from water and industrial effluents.
  • Digital Carbon Bank, based in Alberta, Canada, provides a carbon solution tailored for the energy industry.
  • Chandler, Arizona-based EarthEn provides compressed carbon dioxide-based energy storage and artificial intelligence solutions allowing grid owners/operators to be completely renewable.
  • H Quest Vanguard, from Pittsburgh, provides green hydrogen at a five to 10 times lower cost to users of natural gas to decarbonize industrial heat.
  • Calgary, Alberta-based Highwood Emissions Management's SaaS platform allows oil and gas companies to understand their emissions and develop robust plans to reduce them.
  • Icarus RT, from San Diego, California, improves photovoltaic efficiency while enabling useful heat energy storage.
  • Los Altos, California-based Khepra has developed a chemical manufacturing platform for the low-cost, sustainable production of agrochemicals.
  • Binghamton, New York-based Natrion’s electrolyte is a drop-in solid-state battery component that can be rapidly implemented into existing batteries.
  • Oceanways, based in London, provides low-cost, flexible and scalable zero-emission underwater "virtual pipelines" to energy producers.
  • Relyion Energy, from Santa Clara, California, is developing battery usage and intelligence solutions with deeper data and insights for retired electric vehicle batteries.
  • Massachusetts-based Triton Anchor provides a more cost-effective anchoring solution for offshore clean energy with minimal environmental impact.
  • TROES, from Markham, Ontario, provides a 4-in-1 microgrid solution with integrated hardware and software for a streamlined energy storage experience.
  • Mexico City-based Tycho Solutions supports clean energy project developers by saving time and money during the critical project-siting process.
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A panel of Houston innovators explained how impact investment isn't charity. It provides both financial and societal returns. Photo courtesy of SWAN

Houston experts shine spotlight on impact investing following angel network expansion

calling for impact

Houston innovators called for existing and potential investors to focus on impact investing — for the improvement of both society and your bottom line.

SWAN Impact Network, which announced its expansion into Houston earlier last month, is an investment organization that prioritizes funding mission driven startups and educating angels on how to analyze impact investment companies. The organization hosted a launch event and panel at the Ion last week to discuss the process and goals of impact investing and highlighted their own success stories as angel investors. The panelists included Bob Bridge, Kerri Smith, and Emily Reiser, who were moderated by Grace Rodriguez, executive director of Impact Hub Houston.

Emily Reiser, associate director of the Texas Medical Center’s innovation team, said impact investing, though focused on improving people’s lives through innovations, should still rely on typical business models and return profiles.

“It’s not charity investment, it’s investing with an eye towards how that investment is going to also return to the greater society as well as back to your pockets,” Reiser says.

As there was a mix of prospective angel investors and entrepreneurs in attendance at the event, Reiser encouraged the founders to have formal business plans in place before meeting with investors, from setting up customer feedback systems to budgeting estimates.

“In the impact space you’ll get some great enthusiasm from people who want to join your mission to save lives, or change the world, or save the planet but make sure you do all the rest of the work behind that to build out the rest of your business model, figure out how you’re going to sell, get it optioned, and on the market,” Reiser says.

Bob Bridge, the founder and executive director of SWAN, stressed the importance of examining long term consequences of impact-driven startups. Bridge illustrated the importance of doing research into how these startups could unintentionally harm communities before investing in them by discussing the well known shoe manufacturer TOMS, whose business model revolved around matching each pair of purchased shoes by donating a pair to people in developing countries, putting local manufacturers out of business.

“These companies are often just now entering the market place so they can’t measure their actual impact results yet because they’re not delivering services or products yet,” Bridge says. “We look for them to have some sort of data to give us a clue if what they’re doing is going to work … convince us there is efficacy to what you are doing and that your impact solution is competitive.”

Bridge also adds there is no concrete definition of impact investing because every society has different needs to be met through creative solutions, from developing more robust technology to encouraging the hiring of underrepresented minority groups. When making decisions over which companies to invest in, Bridge says he also prioritizes startup teams that are collaborative and transparent.

“We don’t invest in Steve Jobs' kind of personalities … We want people who are always learning from their customers, competitors, and employees,” he explains.

Kerri Smith, executive director of the Rice Alliance Clean Energy Accelerator program, says her team readies their emerging startups to tackle meetings with investors by asking them to quantify the impact of their technology on users.

“We’re seeing a lot of investors as well as boards of directors requiring companies to be more responsive to those kinds of things,” Smith says. “We try to prepare the startups in ways that will make them more ready to answer questions about the impact that they’re having societally as well as financially.”

Rice University is one of the founding partners of the science foundation’s Southwest I-Corps Node. Photo via Rice University/Twitter

Houston university granted $1.2M to expand STEM-focused initiative

science support

Rice University is receiving a five-year $1.2 million grant from the National Science Foundation to expand a program that helps faculty members, researchers, and doctoral students commercialize STEM-oriented technology.

Rice is one of the founding partners of the science foundation’s Southwest I-Corps Node. Rice and the two other founding partners are sharing a $15 million grant to help add five universities to the program.

Rice, Texas A&M University, and the University of Texas established the Southwest node in 2014. The five schools forming a new hub within the node are the University of Texas at San Antonio, the University of Texas at El Paso, Oklahoma State University, New Mexico State University, and Louisiana State University.

The foundation’s I-Corp program not only boosts STEM-related technologies developed at universities, but it also provides $50,000 grants for STEM-based faculty members and doctoral students to participate in a six-week training program to help researchers bring technologies from the lab to the marketplace. Over 1,000 startups have been formed after completing the I-Corps program; they have raised more than $750 million in funding.

Kerri Smith, associate managing director of the Rice Alliance, leads the university’s I-Corps program, along with Kaz Karwowski, executive director of the Rice Center for Engineering Leadership, and Jessica Fleenor, a Rice Alliance I-Corps teaching assistant and I-Corps program manager.

“Thanks to the Rice Alliance’s more than two decades of leadership, Rice has built an entrepreneurial culture on campus, served as a founding member of the I-Corps program, and provided entrepreneurial education to hundreds of faculty and students,” says Reginald DesRoches, president of Rice.

Rice has received more than $3.1 million in National Science Foundation grants for the I-Corps program, plus about $1.3 million as part of the I-Corps node. Rice faculty members and researchers have received more than $600,000 in I-Corps grants.

Previous I-Corps participants at Rice include:

  • Volumetric Biotechnologies, a startup founded by Jordan Miller, an assistant professor of bioengineering assistant professor, and based on Miller’s 3D organ-printing technology. Volumetric was acquired last year by 3D Systems for up to $400 million.
  • SPLAY (formerly Arovia), which completed the I-Corps program in 2015. Through two Kickstarter campaigns, the company has successfully raised money for its high-definition, portable, large-scale computer display technology.
This week's roundup of Houston innovators includes Kerri Smith of the Rice Alliance, Trevor Best of Syzygy Plasmonics, and Muriel Foster of gBETA Houston. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from cleantech to startup acceleration — recently making headlines in Houston innovation.


Kerri Smith, managing director of the Rice Alliance's Clean Energy Accelerator

Kerri Smith of the Rice Alliance joins the Houston Innovators Podcast to discuss Rice's Clean Energy Accelerator. Photo courtesy of Rice

As the managing director for the Rice Alliance for Entrepreneurship and Technology's Clean Energy Accelerator, Kerri Smith is focused not only on the program's cohorts but on supporting the Houston cleantech ecosystem as a whole. CEA works with Greentown Houston, which is just next door to the program's home at The Ion, and the Greater Houston Partnership's Houston Energy Transition Initiative.

"Rice Alliance has a strong history of demonstrating collaboration with a number of organizations," Smith says. "I think one of the primary benefits that we have in these collaborative opportunities is to ensure that we are collectively building a capable and diverse pipeline of talent to solve for these problems and provide them with access to experiencing all of the benefits of our ecosystem."

Smith shares more about what she's looking for in the second cohort of CEA on a recent Houston Innovators Podcast episode, as well as what she sees as Houston's role in the energy transition. Click here to read more and stream the episode.

Trevor Best, co-founder and CEO of Syzygy Plasmonics

Trevor Best, CEO of Syzygy Plasmonics, joins the Houston Innovators Podcast to discuss the growth of his cleantech startup. Photo courtesy of Syzygy

Trevor Best is gearing up to fundraise for and scale his cleantech startup, Syzygy Plasmonics. The company has also grown its team to 60 people and is preparing to move into a new 45,000-square-foot manufacturing facility in Pearland this summer.

"What we're seeing is the market's appetite for our kind of technology — deep tech for decarbonization in energy and chemicals — is really high. If we want to meet global demand for our product, we need to get ready to scale," Best says on the Houston Innovators Podcast.

Best is keeping a close eye what the market will be looking for, and the interest seems to be in hydrogen as a clean energy solution, which has positioned Syzygy in a great place. Click here to read more and stream the episode.

Muriel Foster, director of gBETA Houston

Muriel Foster, a native Houstonian, is the new director of gBETA Houston. Image via LinkedIn

A national startup accelerator has announced its fifth local cohort, which includes five Houston companies participating in the spring 2022 class, and the new leader that will oversee the program. Muriel Foster is the newly named director of gBETA Houston, which is designed to help guide early-stage startups find early customer traction, connect with mentors, and more.

“The five companies selected for the Spring 2022 cohort tackle unique problems that have propelled them to create a business that solves the issues they once faced," Foster says in a news release. "From public speaking, apparel comfort, and food delivery from underrepresented restaurant owners, these founders have found their niche and are ready to continue to make an enormous impact on the Houston ecosystem."

A Houston native, she has her master’s in public administration from Texas Southern University and a bachelor’s in marketing from Oklahoma State University. Her background includes work in the nonprofit sector and international business consulting in Cape Town, South Africa, and she's worked within programming at organizations such as MassChallenge, BLCK VC, and now gener8tor. Click here to read more.

Kerri Smith of the Rice Alliance joins the Houston Innovators Podcast to discuss Rice's Clean Energy Accelerator. Photo courtesy of Rice

Cleantech accelerator leader looks forward to new cohort and making an impact on Houston's energy transition

HOUSTON INNOVATORS PODCAST EPISODE 134

Kerri Smith knows accelerators. Through her over 18 years at Rice Alliance, she's been responsible for overseeing several and was on the founding leadership team of Houston's first energy tech startup accelerator, SURGE. After years of focusing you accelerating Rice University's student-focused program, Owl Spark, she's transitioned back into the energy tech space.

"I've worked with many types of founders. There's not one unique characteristic that everyone has," Smith says on the Houston Innovators Podcast. "Our goal is to help move them along and help them move the needle. At the end of the day, we want them to have a good experience and to meet their goals and objectives."

The Rice Alliance's Clean Energy Accelerator launched last summer with its inaugural cohort of 12 cleantech startups, which represented energy sectors from solar and wind innovations to hydrogen, geothermal, and more. Smith says the startups represented a wide range of stages and were from all over — only two companies were from Houston originally. The out-of-town companies were able to make critical partnerships in town and set up a presence and a home here.

"We were able to build a family-like culture among our group, and that was something that was wildly appreciative," Smith, who serves as executive director of the program, says.

Applications for Class 2 of CEA are open until May 31. While the program will offer the same access to mentorship and opportunities, the program will change slightly. CEA will focus on seed and series A-stage companies and will be a hybrid program. Throughout the 10 weeks, which begins in the fall instead of the summer this year, founders will visit Houston three times at the beginning, middle, and the end of the accelerator. Each startup will receive a grant to cover the expenses of the equity-free program.

CEA is just one part of a greater ecosystem of innovation under the umbrella of Rice University, which includes the Rice Alliance for Technology and Entrepreneurship, the Liu Idea Lab for Innovation and Entrepreneurship, The Ion Houston, Owl Spark, and more. All these entities also play into the greater Houston area's innovation ecosystem.

"Rice Alliance has a strong history of demonstrating collaboration with a number of organizations," Smith says. "I think one of the primary benefits that we have in these collaborative opportunities is to ensure that we are collectively building a capable and diverse pipeline of talent to solve for these problems and provide them with access to experiencing all of the benefits of our ecosystem."

With CEA specifically, some of these collaborations include working with Greentown Houston, which is just next door to the program's home at The Ion, and the Greater Houston Partnership's Houston Energy Transition Initiative.

"We're a cog in the wheel. We do really well with that. We play well with others – in ways that the founder has a good experience and can benefit," Smith says.

Smith shares more about what she's looking for in the second cohort of CEA on the podcast episode, as well as what she sees as Houston's role in the energy transition. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

This week's roundup of Houston innovators includes Juliana Garaizar of Greentown Houston, Misha Govshteyn of MacroFab, and Kerri Smith of the Rice Alliance. Courtesy photos

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to two local innovators, as well as one honorary Houstonian, across industries — energy, manufacturing, and more — recently making headlines in Houston innovation.

Juliana Garaizar, head of Greentown Houston and vice president of Greentown Labs

Juliana Garaizar is transitioning her role at Greentown Houston. Courtesy photo

Juliana Garaizar has a new role within Greentown Labs. She's lead the local team as launch director, and now is taking a new role now that Greentown Houston has opened its doors. Garaizar recently discussed with InnovationMap why now is the perfect time for Greentown to premiere in Houston.

"I think that if Greentown had happened one year before or even one year later, it wouldn't be the right time. I really believe that our main partners are transitioning themselves — Shell, Chevron, and many others are announcing how they are transitioning," she says. "And now they look at Greentown as an execution partner more than anything. Before, it was a nice initiative for them to get involved in. Now, they are really thinking about us much more strategically." Click here to read more.

Misha Govshteyn, CEO of MacroFab

Misha Govshteyn joins the Houston Innovators Podcast to discuss the evolving electronics manufacturing industry. Photo courtesy of MacroFab

Electronics manufacturer and MacroFab, run by CEO Misha Govshteyn, much like the rest of the business world, was not immune to the effects of the pandemic. But as some business returned last summer, Govshteyn says MacroFab bounced back in a big way.

"In a lot of ways, the concepts we've been talking about actually crystalized during the pandemic. For a lot of people, it was theoretically that supply chain resiliency is important," Govshteyn says on this week's episode of the Houston Innovators Podcast. "Single sourcing from a country halfway around the world might not be the best solution. ... When you have all your eggs in one basket, sooner or later you're going to have a break in your supply chain. And we've seen nothing but breaks in supply chains for the last five years." Click here to read more.

Kerri Smith, interim executive director of the Rice Alliance Clean Energy Accelerator

A new clean energy accelerator has announced its first cohort. Photo via rice.edu

The Rice Alliance Clean Energy Accelerator, a 12-week program that will prepare startups to grow their business, connect them with strategic partners and mentors, launch pilots, and fundraise, has named its inaugural cohort.

"We were impressed with the quality, potential and range of clean energy solutions being commercialized by our applicant pool and took great care in assessing their potential as well as our ability to meet their identified needs," says Kerri Smith, the accelerator's interim executive director. "The selection process was very competitive. We had a difficult time paring down the applications but are looking forward to working with our first class of 12." Click here to read more.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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