This week's Houston innovators to know roundup includes Harvin Moore, James Lancaster, and Joshua Baer. Courtesy photos

Today starts the Houston Tech Rodeo — a week full of innovation-focused events — and its sure to corral entrepreneurs and investors across the city spur discussions of innovation and technology.

This week's Houston innovators to know includes the man at the helm of the organization behind the Tech Rodeo, plus two investors that are making moves in Houston as well as statewide.

Harvin Moore, president of Houston Exponential

Courtesy of HX

Houston Exponential has helped to coordinate over 30 innovation-focused events for the inaugural Houston Tech Rodeo, which will take place March 2 to 6 — in coordination with the start of the Houston Livestock Show And Rodeo — and will feature panels about diversity, reverse pitch events with startups and accelerators, on-stage office hours, and more.

"Really one of the things that makes a tech ecosystem like Houston really work and purr is when people get together, and people are able to bump into each other and bounce ideas off each other. Businesses do well, ideas thrive, and things happen," Harvin Moore, president of HX, says on the Houston Innovators Podcast. "We basically saw this as an opportunity to let the startup development organizations in town schedule their events around a particular week that really look good on a calendar."

Click here to read more and stream the episode.

James Y. Lancaster, Texas branch manager for Arkansas-based VIC Technology Venture Development

Courtesy of VIC

James Lancaster, Texas branch manager for Arkansas-based VIC Technology Venture Development, knows most startups fail for one of three reasons — no market need, running out of money, and not having a strong team. In his most recent guest article for InnovationMap, Lancaster dives into this third reason with key things founders must think about to give their startup the best shot at success.

"Like market need, evaluating the management team is on virtually every venture capitalist's list of what they look for in their target investments and you need to get it right," Lancaster says.

Click here to read more.

Joshua Baer, founder and CEO of Capital Factory

Courtesy of Capital Factory

While not technically a Houstonian, this Austinite gets an honorary title for his work here. Austin-based accelerator and investment organization Capital Factory recently merged with Station Houston, and CEO and Founder Joshua Baer says it's just the beginning of his focus on Houston startups.

"In total right now, we have 40 companies ever that have joined our accelerator from Houston, which is still a pretty significant number," he tells InnovationMap. "This year, we expect more than 40 companies to join the accelerator from Houston."

Click here to read more.Click here to read more.

Capital Factory has doubled down on Houston, and Founder and CEO Josh Baer shares how it's all part of his Texas Manifesto. Photo courtesy of Capital Factory

Capital Factory founder plans to double portfolio companies in Houston this year

Q&A

A statewide accelerator program has doubled down on Houston, and it's just the beginning.

Austin-based Capital Factory, which also has a presence in Dallas, recently merged with Station Houston in an effort to expand their mentor network and grow its startup portfolio with the addition of Houston companies.

As of today, Capital Factory has 40 startups from Houston in its portfolio, says Josh Baer, founder and CEO of Capital Factory, and Baer says he expects to add an additional 40 in 2020. The Station merger will help spur that growth and also play into Capital Factory's greater Texas Manifesto mission to advance innovation statewide.

"This is not just about adding one more city," Baer says. "It's really about how there's a lot of unique things that Houston brings that are going to make the whole picture a lot stronger."

Baer sat down with InnovationMap to discuss the details of the merger, how Capital Factory will be tuned into The Ion, and how Houston startups can tap into Capital Factory — both locally and at this year's SXSW.

InnovationMap: Capital Factory has been active in Houston for a few years and announced a partnership with The Cannon last year. How has that activation been going?

Josh Baer: We've been in Houston for quite a while now. We started off with our Texas Manifesto almost three years ago and the first thing we did was a listening tour of all the different cities, and we spent a bunch of time in Houston.

Part of the growth we've seen in part is from our partnership with The Cannon as they've opened. They've been a great partner allowing us to reach all of Houston because Houston is really big. It's not like Austin where you can primarily service from one place. We're not builders, that's not our role. We want to be wherever everybody else is doing great things. And that's The Cannon, The Ion, and the Texas Medical Center and all the other places too. There's lots of room for different flavors and focuses and groups, and we need to be at all those places.

IM: What's Capital Factory's presence in Houston and how do you see it growing?

JB: Last year, we hired our first two employees in Houston — that was Kendrick and Brittany, our mentor coordinator and venture associate — so that we could build our mentor network and connect them into the rest of Texas and source the best companies and connect them to the rest of Texas. Last year with those two employees, we brought in 14 Houston companies into our accelerator.

In total right now, we have 40 companies ever that have joined our accelerator from Houston, which is still a pretty significant number. This year, we expect more than 40 companies to join the accelerator from Houston.

IM: How will Capital Factory be involved in The Ion?

JB: Well we are so happy that we have exactly the role we would want to have at The Ion. And that is having some prime space right in the middle of it, and we're located not in the coworking space but in the event space because that's really, we want to be — we want to be where everyone is meeting and activating.

One of the things that we'll focus on is building out the mentor network at The Ion and connecting it into the rest of our mentor network. We're not going to be the only accelerator there. There's going to be a bunch of accelerators there. There's gonna be a bunch of mentor networks. And we're excited to partner with all of those and many more probably bring great people into our networks. I'm pretty confident we'll be the biggest mentor network there and we'll be the default one. We'll be the main one that everybody's part of, and particularly because it connects into everything else. But we'll do that in a really collaborative way.

IM: You kind of dove headfirst into the Dallas innovation ecosystem with a real estate play. Why did making these partnerships make more sense for Houston?

JB: Well, Capital Factory isn't backed by a big university or a billionaire, or a pension fund or something. It's really backed by entrepreneurs. And so while we're fortunate that we do have capital to invest in these startups, our value is not really like the capital like that builds buildings. It takes a lot of money and a lot of capital and that comes from universities and different types of investors and from communities right from the city and others that are part of that.

And so in Dallas, when we looked at that market, there was a real need — nobody was building a place like this, so we had to. We needed a center of gravity. Dallas is big too — other people will build more and we're going to need to be at those places too, just like in Houston.

But in Houston, not only did we are Texas Medical Center, and then we already had The Cannon and there's going to be The Ion, which are hundreds of thousands of square feet of prime real estate that's going to be amazing. We don't want to recreate that or compete with that. We want to be part of that.

So, if somebody else is already putting up tens or a hundreds of millions of dollars to build the building, I don't need to do that. I want to be part of that. My value is not capital. It's bringing the people into the building. It's activating the building and bringing programming into it, and that's where Capital Factory really adds the most value.

IM: How exactly did the merger with Station Houston come about?

JB: You know, it goes all the way back to the very beginning. I'm pretty sure that I was one of the first people that the founders of Station talked to when they were getting started when Emily and Blair and others were working on it. You know, Capital Factory was the place they came to look at. And, I was friends with all of them, and we were very open book about it, and said, "Hey, you know, here's how we work. We should see how we can work together." Because of that, we've always had a good relationship — Station was the first place that we ever went on a bus trip to Houston. We've had lots of overlap between our mentor networks and startups that we work with and others.

And Station has gone through some different changes over the years — leadership and their model evolved from for profit to nonprofit and onward. And through those changes, we just kept moving closer and closer together. It became really clear, especially with the launch of The Ion, that it was really the perfect opportunity for us to align ourselves even more closely and really connected fully into the rest of what's happening in the rest of the state.

IM: I’ve spoken to Gabriella Rowe, former CEO of Station, about it and she really sees it as a return to Station’s roots as an organization. How do you see the merger for Capital Factory?

JB: Well for us, you know, I really like the analogy of a stool. Everybody knows that to have a good foundation, a stool needs to have three legs. And, our mission in connecting Texas together through our Texas Manifesto. [Austin and Dallas were] working and working well, but it still wasn't a strong foundation. Ramping this up across Dallas and Houston, it completes the foundation and gives it a really strong footing and a really powerful footing to make it a Texas wide play.

We don't see this as a cookie cutter kind of thing. Each city is different. Each city has different needs and brings different things [to the table]. And we see that for sure from Houston. The type of entrepreneurs and companies that we've worked with are different. They're working on big, messy problems — robots and dangerous things. And that is exciting and attracts other partners — the big companies and the army and others that want tap into that too. And so, this is not just about adding one more city. It's really about how there's a lot of unique things that Houston brings that that's going to make the whole picture a lot stronger.

IM: What’s the status of the merger at this point?

JB: The paperwork's done, and we're taking a very intentionally slow process with [the execution of the merger]. We told everybody, "you shouldn't expect to see a lot to change fast." We want to be careful and thoughtful. So, we're going to listen a lot, and we're going to make changes slowly. And our goal is that for all the Station members, this is just a value add. They get everything they had before, plus now they get more. Now they get access to the Capital Factory network now, and they get access over time to more at the ion.

[But bigger picture,] it's not done at all. We barely started. We're still really listening and learning, so I don't feel like much has happened yet. The beginning part is, right now, every station Houston member has access to the rest of the Capital Factory network — both physically and virtually. They can go to Austin or Dallas. They can go to The Cannon. And more importantly than that, they can use our online network of union.vc, which is a website where they can log in, create a profile, and they can see all the other startups and mentors across the state and they can be seen by them. And that's what we can do to help connect them all together.

IM: Capital Factory kept Station’s remaining staff, right? Will Capital Factory be hiring more staff in Houston? 

JB: Right, we now have five Houston employees, three of them used to be Station's. We do expect to hire, but we don't have any specific roles to announce, but we have over a dozen people on the team in Dallas now two years into it.

IM: How can Houston startups make the most of SXSW this year?

JB: Honestly, our goal is to be the easy button. The first thing is come to Capital Factory. Capital Factory is an official South by Southwest house. This year, it's all official programming. And of course, the type of programming that you're going to see is focused on startups and government and defense.

We'll have Fast Company, Deloitte, Booz Allen, the army, and the air force — all kinds of other people there. And so that's an easy place to plug in. And for entrepreneurs who are part of our network, they don't have to have South badge to do that. They can be part of what's going on at Capital Factory as members.

IM: For startups wanting to get involved with Capital Factory, what's step one?

JB: The first step is to come to The Cannon or Station and meet us possible. And the person that first person they want to meet is Brittany Barreto, who's our venture associate. That's her job is to scout startups and meet them and help kind of bring them into the funnel.

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Pharma giant considers Houston for $1B manufacturing campus

in the works

Another pharmaceutical giant is considering Houston’s Generation Park for a manufacturing hub.

According to a recent filing with the Texas Jobs, Energy, Technology and Innovation (JETI) program, Bristol Myers Squibb Co. is considering the northeast Houston management district for a new $1 billion multi-modal pharmaceutical manufacturing campus.

If approved, the campus, known as Project Argonaut, could create 489 jobs in Texas by 2031. Jobs would include operations technicians, engineering roles, administrative and management roles, production specialists, maintenance support, and quality control/assurance. The company predicts annual average wages for these positions to be around $96,000, according to the filing.

The project currently includes the 600,000-square-foot facility, but according to the filing, Bristol Myers Squibb “envisions this site growing in scale and capability well beyond its opening configuration."

The Texas JETI program offers companies temporary school property tax limitations in exchange for major capital investment and job creation. E.R. Squibb & Sons LLC applied for a 10-year tax abatement agreement in the Sheldon Independent School District.

The agreement promises a $ 1 billion investment. Construction would begin in 2027 and wrap in 2029.

“The proposed project reflects [Bristol Myers Squibb Co.’s] enduring commitment to bringing innovative medicines to patients and ensuring the long-term supply reliability they depend on,” the filing says. “The proposed project is purpose-built to support and manufacture medicines spanning multiple therapeutic areas and modalities, positioning the site as a long-term launch and commercial campus for decades to come. These medicines will provide therapies to the [Bristol Myers Squibb Co.’s] patients located in markets both nationally and internationally.”

The Fortune 100 company is considering 16 other cities for the new manufacturing facility in the Central and Eastern markets in the U.S. According to the Houston Chronicle, Bristol Myers Squibb Co is still in the “evaluation process” for its potential manufacturing site.

Last fall, Eli Lilly and Co. selected Generation Park for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

Houston health tech co. lands NIH grant for AI cancer prediction tool

fresh funding

Houston-based CellChorus and Stanford Medicine were recently awarded a Phase I Small Business Innovation Research grant for the company's AI platform to test how certain cancer patients will respond to therapies.

The funding comes from the National Cancer Institute of the National Institutes of Health. According to a filing, the grant totaled just under $400,000.

CellChorus, which spun out from the University of Houston’s Technology Bridge, has developed TIMING (Time-lapse Imaging Microscopy In Nanowell Grids), which analyzes the behavior of thousands of individual immune cells over time and can identify early indicators of treatment success or failure.

The company will work with Stanford's Dr. David Miklos and Dr. Saurabh Dahiya, who have built the Bone Marrow Transplantation and Cell Therapy Biobank. The biobank manages and stores biological samples from patients treated at their clinic and in clinical trials.

"Predicting which patients will achieve durable responses after CAR-T therapy remains one of the most important challenges in the field,” Miklos said in a news release. “We aim to uncover functional cellular signatures that can guide treatment decisions and improve patient outcomes.”

The project will specifically profile cells from patients with relapsed/refractory large B-cell lymphoma (r/rLBCL). According to CellChorus, only about half of r/rLBCL patients who receive CAR-T therapy "achieve a durable, long-term remission." Others do not respond to therapy or experience relapse.

“The sooner we know whether a cancer therapy is working, the better. To maximize patient benefit, we need technology that can provide a robust and early prediction of response to therapy. The technology needs to be scalable, cost-efficient, and capable of rapid turnaround times,” Rebecca Berdeaux, chief scientific officer of CellChorus, added in the release. “We are excited to work with Drs. David Miklos and Saurabh Dahiya and their colleagues on this very important project.”

CellChorus has previously received SBIR grants from federal agencies, including a $2.5 million award in 2024 from its National Center for Advancing Translational Sciences (NCATS) and a $2.3 million SBIR Fast-Track award from the National Institute of General Medical Sciences in 2023.

Houston museum showcases America's founding documents in rare exhibit

Experience History

As the United States prepares to celebrate its 250th birthday, Houstonians have a chance to see rare documents from the founding of the nation. Freedom Plane National Tour: Documents That Forged a Nation, presented by the National Archives Foundation, will be on display at the Houston Museum of Natural Science through Monday, May 25.

The collection includes a rare engraving of the original Declaration of Independence; official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton; a draft of the Bill of Rights; the Treaty of Paris, the documented that recognized America's independence from Great Britain; and the tally of votes approving the Constitution.

The National Archives specifically chose Houston as one of only eight cities in the country to host the exhibit as a means to help the documents reach a wider audience outside of the main hub of semiquincentennial events in New England and the Washington, D.C. area.

"One of the things we decided when we put the tour together because we wanted to be off the East Coast," said Patrick Madden, CEO of the National Archives Foundation, who was onsite for the exhibit's opening in Houston. "There's a lot of 250th celebration stuff happening in the original 13 colonies. How do we get it to major markets where larger numbers of people can see it? So in the case of Houston, obviously, [is a] major market in this part of the country, but also we've partnered with the museum twice before with National Archives exhibits, so we knew that they would be up to the task of handling the exhibit and the crowds."

The star of the collection is a rare engraving of the original Declaration of Independence. Secretary of State and future president John Quincy Adams commissioned 200 exact replicas of the document from engraver William J. Stone in 1823. Less than 50 now remain. Madden joyfully pointed out that there are errors in this document, a potent reminder that the men who forged a nation made mistakes.

"There's a couple of typos in it where they had to make corrections," said Madden. "So even the founders, you know, they're all human. That resonates because here these people are making this move against the most powerful nation in the world and putting their lives on the line for a country based on ideas."

Other impressive parts of the collection include official Oaths of Allegiance signed by George Washington, Aaron Burr, and Alexander Hamilton, as well as one of the drafts of the Bill of Rights. Many states would not ratify the Constitution until certain rights were included in the document, leading to Washington going on a national tour assuring state leaders enshrining protections was first on the list. The draft copy on display specifically shows the First Amendment in progress.

Houston is the fourth stop on the exhibition's tour, which will take the documents to Denver, Miami, Dearborn, and Seattle through the summer. Freedom Plane is just one part of a larger patriotic celebration at the HMNS, which includes a film series celebrating American science and culture and general Americana decoration throughout the main hall.

Admission to Freedom Plane is free to the public, but separate from general admission to the museum. Space is limited, and passes are available on a first-come, first-serve basis. Non-members should expect long waits or the possibility that the day's passes are sold out. Only museum members can reserve passes for specific times. Flash photography is prohibited due to the fragile nature of the documents.

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This article originally appeared on CultureMap.com.