This week's innovators to know are focused on using artificial intelligence in data management, banking for startups, and 5G awareness in Houston. Courtesy photos

This year, Houston's innovation ecosystem is set to change tenfold — from the rise of 5G to burgeoning startup and entrepreneurial hubs emerging across town.

Today's featured innovators know a bit about these movements — from an entrepreneur using artificial intelligence in data management for his clients to a banking exec who went all-in on startups.

Tony Nash, founder and CEO of Complete Intelligence

tony nash

Courtesy of Complete Intelligence

Every company wishes they have a crystal ball when it comes to making business decisions, and while a physical iteration of that wish isn't possible, Tony Nash has developed the next best thing for his clients at his startup, Complete Intelligence.

Founded in 2015, Complete Intelligence is an AI platform that forecasts assets and allows evaluation of currencies, commodities, equity indices and economics. The Woodlands-based company also does advanced procurement and revenue for corporate clients.

"We've spent a couple years building this," says Nash in a recent InnovationMap interview. "We have a platform that is helping clients with planning, finance, procurement and sales and a host of other things. ... We built a model of the global economy and transactions across the global economy, so it's a very large, very detailed artificial intelligence platform." Read more.

Brian Richards, Houston innovation hub director at Accenture and board member at Houston Exponential

brian richards

Courtesy of Accenture

The rise of 5G in Houston feels familiar to Brian Richards. He writes in a recent guest column that the development of the technology is similar to the moment in Houston's history when NASA landed a man on the moon.

There are a few similarities Richards expresses in his article, as well as providing more information about 5G itself, but the undeniable fact is 5G will create a lasting impact in Houston.

"Above all, as Houston continues to race toward building a world-class innovation ecosystem and a sustainable, thriving economy, we simply can't take our foot off the gas in the 5G race — much like the moon race," he writes. "It's an imperative that the region continue to lead in 5G network adoption and that our local industries and businesses envision, plan and develop new ways of working." Read more.

Jimmy Allen, executive vice president and chief operating officer of Texas Citizens Bank

jimmy allen

Courtesy of Texas Citizens Bank

It's become a bit of a trend to see banks taking a bet on startups — Capital One, for instance, has even entered the coworking industry itself. And one Houston-area bank has become an early adopter of this trend locally.

Jimmy Allen, executive vice president and chief operating officer of Texas Citizens Bank, says the bank's new 3,900-square-foot location — its seventh branch in the Houston area — fits perfectly within The Cannon's 120,000-square-foot building in West Houston, which Texas Citizens helped build. The branch opened in December 2019; the grand opening is planned for January 2020.

"Owner-operated businesses are both the genesis of our business model and [a] key customer segment served," says Allen, who was named to his position in November. "A subset of that group certainly includes young, relatively new companies, which favor the current trend in coworking or live-work-play communities." Read more.

As a part of a national trend, a Houston bank has moved into a space in Houston's largest coworking hub. Texas Citizens Bank/Facebook

Local bank commits to Houston startup scene by setting up shop in The Cannon

Moving in

Pasadena-based Texas Citizens Bank is getting cozy with current and potential customers at its new branch within The Cannon coworking campus.

Jimmy Allen, executive vice president and chief operating officer of Texas Citizens Bank, says the bank's new 3,900-square-foot location — its seventh branch in the Houston area — fits perfectly within The Cannon's 120,000-square-foot building, which Texas Citizens helped build. The branch opened in December 2019; the grand opening is planned for February 2020.

"Owner-operated businesses are both the genesis of our business model and [a] key customer segment served," says Allen, who was named to his position in September. "A subset of that group certainly includes young, relatively new companies, which favor the current trend in coworking or live-work-play communities."

Aside from offering traditional banking products like loans and checking accounts, Texas Citizens serves as a financial consultant to startups that are occupants of The Cannon, according to Allen. Texas Citizens is now the official bank for The Cannon and Cannon Ventures, an angel investment network housed at the coworking space.

The Cannon is at 1334 Brittmoore Rd. in the Energy Corridor. It operates two other entrepreneurial hubs in Houston — one downtown and the other in the Post Oak area. Allen says branches could pop up in other locations of The Cannon.

"When we first opened the bank in 2006, our goal was to advise and assist owner-operated businesses … in the greater Houston area," Duncan Stewart, chairman and CEO of Texas Citizens, says in a release. "Our new location helps further that goal. This unique placement allows us to tap into new markets and assist more entrepreneurs in their financial and operational development."

Stewart plans to spend time at his bank's new branch at The Cannon, according to Texas Citizens. Irene Duque, senior vice president, manages the branch.

Texas Citizens' other branches are in the West University area of Houston as well as Pasadena, Baytown, Clear Lake, Nassau Bay, and Rosenberg. Its assets exceeded $540 million as of June 30, 2019.

Texas Citizens' outpost at The Cannon is part of a growing relationship between coworking spaces and banks. In some cases, banks are leasing vacant space to coworking tenants or are creating flexible office space within empty square footage, according to American Banker. In other cases, banks are tenants in coworking spaces, as is the situation with Texas Citizens at The Cannon.

One banking giant, Capital One, has entered the coworking sector in a significant way. The bank has established free-to-use coworking cafés that offer traditional financial services but also furnish access to Wi-Fi, charging stations, workspaces, community rooms, coffee, and pastries.

Across the country, Capital One operates roughly 40 cafés. None of the them are in the Houston area.

"The space feels WeWork-y, with marble tables, brand new chairs, spotless concrete floors, and private study rooms. The aesthetic is 'venture capital,'" a writer for Los Angeles magazine observed in November 2019 after visiting a Capital One Café.

The first Capital One Café opened in 2015 in Boston.

"In modeling the cafés, Capital One responded to what it heard from consumers: Bank branches were intimidating and stressful," the Wall Street Journal reported in November 2019. "At the cafés and branches, the employee dress code is relaxed, and customers can open accounts on iPads. The cafés also host community groups and hold workshops such as 'Talking Money With Your Honey,' which focuses on finances in relationships."
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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.