When it comes to 5G, Houston is setting itself up as a leader within the United States. Getty Images

Last year, Houstonians Clayton and Emily Harris became the first commercial 5G customers. Now, a full year later, the Houston has a major seat at the table that's discussing the advancement of 5G technology.

At a forum on Tuesday, October 1, hosted by CTIA and the Center for Houston's Future, experts discussed Houston's role in the conversation about 5G. Here are some overheards from the morning event.

“We cannot take our leadership in 4G for granted as we transition to 5G.”

— Senator Ted Cruz. Cruz's keynote address warns of the United States resting on its laurels in the race to 5G. While the country had the edge on foreign competition for 4G, that doesn't mean 5G will have the same result, he says. In fact, Cruz cites multiple studies that show China and South Korea lead the race in 5G. Deloitte's research found that China has outspent the U.S. by $24 billion and has built 350,000 new sites, while the U.S. has built fewer than 30,000. The study also showed China is prepared to invest $400 billion. This information aside, Cruz tells the crowd that America has the ability to win the race to 5G.

“I think it’s a wonderful story to see how Texas has been leading the way.” 

— Brendan Carr, FCC commissioner. Carr references the Harris family, as well as other Texas cities he's visited that have been working hard to advance 5G. For Carr, expanding and implementing 5G is a huge opportunity for job creation. "The U.S. isn't the only country in the world that wants these jobs," he says to the crowd. "They're not the only country that wants to see the half a trillion dollars in economic growth that's going to come from this next-generation technology."

“I’ll admit, I’m an optimist, but there are significant challenges to making this 5G future a reality.”

— Jesse Bounds, director of innovation for the city of Houston. Bounds cited a few obstacles to overcome. There's a need for massive investment in infrastructure to blanket cities in 5G, and telecom companies are expected to spend $8 billion over the next five years to build this infrastructure, and cities too will need to invest in smart city technology. Consumers will need to pay more for data, and US consumers pay some of the highest rates in the world already. Not to mention the fact that a third of Americans don't have access to home internet. "As we build the infrastructure of the future, we must do so in a way that closes the digital divide so that those Americans can enjoy the same level of opportunity and prosperity that we do," Bounds says.

"Houston’s 5G network performance is 17 times better than the 4G. That’s today, in the very early days of 5G.”

— Paul Challoner, vice president of network product solutions at Ericsson. Challoner tells the crowd that of course this affects speed of data transferring and that is a huge pro for the technology, but there are other important perks for 5G advancement. The tech also affects device density, meaning that, a very large city like Houston, might have issues in dense areas. 5G also improves connectivity in crucial situations, like in the case of a surgeon using a device during surgery. Lastly, Challoner mentioned 5G is the most advanced technology when it comes to cybersecurity.

"One area that I’m most excited about is all the things that we don't talk about. All the applications that haven't yet been imagined, that are being dreamt up by software developers in their dorm rooms."

— Mishka Dehghan, vice president of 5G development at Sprint. Dehghan points out that 10 years ago, no one could have imagined ride sharing, now that is a huge industry with developing technology thanks to mobile data usage. With with the onset of 5G, she says she can't wait to see what technology is created in the next 10 years.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

---

This article first appeared on EnergyCapitalHTX.com.