Hines, which opened its Texas Tower in 2021, is hoping to reach net-zero operational carbon by 2040. Image via Hines

Houston-based real estate giant Hines is on a mission to make its entire global portfolio free of carbon emissions.

Hines recently set a target of its 1,530 properties in 28 countries being net-zero operational carbon by 2040, including the 27.7 million square feet of space it owns or manages in the Houston area. Operational carbon refers to greenhouse gases produced by building operations.

The company says it will accomplish the net-zero goal by reducing emissions through renewable technology, and not by purchasing carbon offset credits.

Peter Epping, global head of ESG (environmental, social, and governance) at Hines, says that because the company has made its carbon-neutral plan public, “investors, developers, engineers, and building managers across our industry can use it to guide their own carbon-reduction efforts.”

Hines notes that the real estate sector emits nearly 40 percent of global carbon emissions related to energy. The World Building Council’s Net Zero Carbon Buildings Commitment calls for decarbonizing half of buildings by 2030 and all buildings by 2050.

“As the impact of climate change is becoming increasingly integrated into our lives every day, the real estate industry has a responsibility to acknowledge this growing problem and take meaningful action to reduce our collective carbon emissions,” Jeff Hines, chairman and co-CEO of Hines, says in a news release. “By seeking to achieve net-zero operational carbon without relying on offsets, Hines wants to raise the bar for sustainability and invest in a plan designed to achieve significant and tangible results.”

To achieve those results, Hines plans to:

  • Halting the use fossil fuels to power buildings in its $90.3 billion portfolio.
  • Reducing energy demand by improving building efficiencies.
  • Boosting reliance on renewable energy.
  • Using “circular systems” to reduce energy waste and enhance efficiency.
  • Promoting carbon capture.

A recent report from Houston-based law firm Vinson & Elkins underscores the economic benefits that the net-zero movement presents to commercial real estate players like Hines.

“Real estate increasingly attracts attention from sustainability-minded investors amid a wider push for ESG considerations in bond and loan markets. … Decarbonizing the real estate industry will likely require trillions of dollars of capital, but there is vast opportunity for environmentally friendly projects to access additional financing sources, often on favorable terms,” Caitlin Snelson, sustainable finance senior associate in the Houston office of Vinson & Elkins, says in a news release.

Beyond real estate, Hines’ net-zero campaign aligns with efforts to transform Houston into a net-zero industrial hub. A whitepaper published by Columbia University’s Center on Global Energy Policy declares that Houston is well-positioned to become a “best in class” net-zero hub.

According to the whitepaper, the hub “could serve as a magnet for new and emerging industries, innovators and entrepreneurs and investment in energy transition companies and resources. Failure to develop a hub could lead to loss of these benefits and opportunities.”

Consulting giant McKinsey & Co. points out that clean hydrogen is emerging as a vehicle to achieve net-zero status and says Houston could evolve into a global hub for clean hydrogen. A Houston hub that’s in place by 2050 could generate 180,000 jobs and an economic impact of $100 billion, according to McKinsey.

“With the right supportive policy frameworks, Texas could become the global leader in clean-hydrogen production, application, development, and exports with Houston at its core; the resulting thriving hydrogen community could push innovation and develop the necessary talent to conceive and deliver hydrogen projects,” McKinsey says.

Laura Hines-Pierce, 38, is the new co-CEO with her father Jeff Hines. Photo courtesy of Hines

Gerald D. Hines' granddaughter named new co-CEO of global real estate powerhouse

boss up

A global real estate juggernaut now has a new — and familiar — face in the executive office. Hines announced that Laura Hines-Pierce has been promoted to co-CEO, joining Jeff Hines, her father.

This move makes Hines-Pierce, 38, one of the youngest CEOs of a major real estate organization and one of only a few women in an often male-dominated industry.

Hines-Pierce was most recently Hines’ senior managing director in the office of the CEO since 2020, and before that, served as the firm’s transformation officer. She is credited with building the investment management platform that launched three flagship funds across the U.S. and Asia with a total current investment capacity of $4.8 billion in equity, translating to $10.8 billion in purchasing power.

Other work included integrated innovation into all areas of the business and further defined the firm’s ESG commitments, per press materials.

While serving as the firm’s transformation officer, Hines-Pierce worked with the co-heads of investment management, the global chief investment officer, and the CEO of capital markets, to refine investment strategy and acquisition efforts.

On-the-ground and grassroots work also included serving as project manager for River Point, a one-million-square-foot development in Chicago. She was also part of the OneHines Women’s Network, which focused on the company’s diversity and inclusion.

Before her Hines tenure, Hines-Pierce worked for Sotheby’s in New York. She graduated from Duke University with a BA in Economics and Art History and received her MBA from Harvard University, per her bio.

As far as next steps, Hines is keeping it in the family: plans include Hines-Pierce’s two brothers, Adam and Matthew Hines, who are expected to join her and Jeff in the office of the CEO.

“I’m proud to become co-CEO and continue the momentum we’re experiencing across the board at Hines,” said Hines-Pierce in a statement. “My father has been the catalyst for our global expansion and growth over the past three decades and I’m excited to partner with him at this pivotal moment for the firm. The pace of innovation in real estate is finally catching up with other industries; my primary focus has always been – and continues to be – positioning Hines at the forefront of those changes.”

Hines is the brainchild of real estate icon Gerald D. Hines, who passed away in 2020 at the age of 95. Gerald Hines engineered his fledgling firm from an entrepreneurial startup in Houston in 1957 into an international powerhouse that has developed, owned, and managed some of the world’s most recognizable architectural landmarks across five continents. The firm boasts nearly 1,500 buildings in 255 cities in 27 countries and some $84 billion in assets.

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This article originally ran on CultureMap.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”