Hines, which opened its Texas Tower in 2021, is hoping to reach net-zero operational carbon by 2040. Image via Hines

Houston-based real estate giant Hines is on a mission to make its entire global portfolio free of carbon emissions.

Hines recently set a target of its 1,530 properties in 28 countries being net-zero operational carbon by 2040, including the 27.7 million square feet of space it owns or manages in the Houston area. Operational carbon refers to greenhouse gases produced by building operations.

The company says it will accomplish the net-zero goal by reducing emissions through renewable technology, and not by purchasing carbon offset credits.

Peter Epping, global head of ESG (environmental, social, and governance) at Hines, says that because the company has made its carbon-neutral plan public, “investors, developers, engineers, and building managers across our industry can use it to guide their own carbon-reduction efforts.”

Hines notes that the real estate sector emits nearly 40 percent of global carbon emissions related to energy. The World Building Council’s Net Zero Carbon Buildings Commitment calls for decarbonizing half of buildings by 2030 and all buildings by 2050.

“As the impact of climate change is becoming increasingly integrated into our lives every day, the real estate industry has a responsibility to acknowledge this growing problem and take meaningful action to reduce our collective carbon emissions,” Jeff Hines, chairman and co-CEO of Hines, says in a news release. “By seeking to achieve net-zero operational carbon without relying on offsets, Hines wants to raise the bar for sustainability and invest in a plan designed to achieve significant and tangible results.”

To achieve those results, Hines plans to:

  • Halting the use fossil fuels to power buildings in its $90.3 billion portfolio.
  • Reducing energy demand by improving building efficiencies.
  • Boosting reliance on renewable energy.
  • Using “circular systems” to reduce energy waste and enhance efficiency.
  • Promoting carbon capture.

A recent report from Houston-based law firm Vinson & Elkins underscores the economic benefits that the net-zero movement presents to commercial real estate players like Hines.

“Real estate increasingly attracts attention from sustainability-minded investors amid a wider push for ESG considerations in bond and loan markets. … Decarbonizing the real estate industry will likely require trillions of dollars of capital, but there is vast opportunity for environmentally friendly projects to access additional financing sources, often on favorable terms,” Caitlin Snelson, sustainable finance senior associate in the Houston office of Vinson & Elkins, says in a news release.

Beyond real estate, Hines’ net-zero campaign aligns with efforts to transform Houston into a net-zero industrial hub. A whitepaper published by Columbia University’s Center on Global Energy Policy declares that Houston is well-positioned to become a “best in class” net-zero hub.

According to the whitepaper, the hub “could serve as a magnet for new and emerging industries, innovators and entrepreneurs and investment in energy transition companies and resources. Failure to develop a hub could lead to loss of these benefits and opportunities.”

Consulting giant McKinsey & Co. points out that clean hydrogen is emerging as a vehicle to achieve net-zero status and says Houston could evolve into a global hub for clean hydrogen. A Houston hub that’s in place by 2050 could generate 180,000 jobs and an economic impact of $100 billion, according to McKinsey.

“With the right supportive policy frameworks, Texas could become the global leader in clean-hydrogen production, application, development, and exports with Houston at its core; the resulting thriving hydrogen community could push innovation and develop the necessary talent to conceive and deliver hydrogen projects,” McKinsey says.

Laura Hines-Pierce, 38, is the new co-CEO with her father Jeff Hines. Photo courtesy of Hines

Gerald D. Hines' granddaughter named new co-CEO of global real estate powerhouse

boss up

A global real estate juggernaut now has a new — and familiar — face in the executive office. Hines announced that Laura Hines-Pierce has been promoted to co-CEO, joining Jeff Hines, her father.

This move makes Hines-Pierce, 38, one of the youngest CEOs of a major real estate organization and one of only a few women in an often male-dominated industry.

Hines-Pierce was most recently Hines’ senior managing director in the office of the CEO since 2020, and before that, served as the firm’s transformation officer. She is credited with building the investment management platform that launched three flagship funds across the U.S. and Asia with a total current investment capacity of $4.8 billion in equity, translating to $10.8 billion in purchasing power.

Other work included integrated innovation into all areas of the business and further defined the firm’s ESG commitments, per press materials.

While serving as the firm’s transformation officer, Hines-Pierce worked with the co-heads of investment management, the global chief investment officer, and the CEO of capital markets, to refine investment strategy and acquisition efforts.

On-the-ground and grassroots work also included serving as project manager for River Point, a one-million-square-foot development in Chicago. She was also part of the OneHines Women’s Network, which focused on the company’s diversity and inclusion.

Before her Hines tenure, Hines-Pierce worked for Sotheby’s in New York. She graduated from Duke University with a BA in Economics and Art History and received her MBA from Harvard University, per her bio.

As far as next steps, Hines is keeping it in the family: plans include Hines-Pierce’s two brothers, Adam and Matthew Hines, who are expected to join her and Jeff in the office of the CEO.

“I’m proud to become co-CEO and continue the momentum we’re experiencing across the board at Hines,” said Hines-Pierce in a statement. “My father has been the catalyst for our global expansion and growth over the past three decades and I’m excited to partner with him at this pivotal moment for the firm. The pace of innovation in real estate is finally catching up with other industries; my primary focus has always been – and continues to be – positioning Hines at the forefront of those changes.”

Hines is the brainchild of real estate icon Gerald D. Hines, who passed away in 2020 at the age of 95. Gerald Hines engineered his fledgling firm from an entrepreneurial startup in Houston in 1957 into an international powerhouse that has developed, owned, and managed some of the world’s most recognizable architectural landmarks across five continents. The firm boasts nearly 1,500 buildings in 255 cities in 27 countries and some $84 billion in assets.

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This article originally ran on CultureMap.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”