Houston innovation hub adds Oxy, United, and Woodside as partners

onboarding

The Ion named three corporate partners ahead of its annual innovation-focused festival. Photo courtesy of the Ion

Houston’s Ion innovation hub has recruited three heavyweight corporate partners, the hub announced earlier this week.

The new partners are:

  • Houston-based energy company Occidental (known as Oxy).
  • United Airlines Ventures, the sustainability-focused VC arm of Chicago-based United Airlines. United operates a major hub in Houston.
  • Australia-based Woodside Energy, which maintains an office in Houston.

Oxy, United Airlines Ventures, and Woodside will share their expertise in support of Ion’s mission to transform Houston into a global innovation ecosystem, according to an Ion news release. In addition, they will participate in Ion programming and network with Ion affiliates. Executives from all three of the new partners will serve on the Ion Leadership Advisory Roundtable.

“Welcoming our newest partners into Ion’s ecosystem is a further testament to our momentum in the aerospace and energy transition,” says Jan Odegard, who became executive director of the Ion in 2021 after a year of holding the interim position. “Each organization brings their own culture of innovation that aligns with what we are doing at the Ion.”

Michael Leskinen, president of United Airlines Ventures, says the VC firm believes “the Ion will be the epicenter for Houston’s rapidly growing innovation community — a one-stop shop to share ideas, foster startups, and to develop relationships with Houston’s brightest companies and academia.”

Oxy, United Airlines Ventures, and Woodside join Ion corporate partners such as:

  • Aramco Americas
  • Baker Botts
  • BP
  • Chevron
  • ExxonMobil
  • Global Custom Commerce
  • Intel
  • Microsoft
  • Transocean

The Ion announced the new corporate partners in advance of the second annual Ion Activation Festival, set for May 17-19. The Ion and Rice Management Co. host the festival, which shines a spotlight on entrepreneurship and innovation in Houston.

Activities will take place primarily at the Ion’s 16-acre campus. To register for the festival, visit the Ion’s website.

The inaugural festival, held in 2022, drew more than 2,500 attendees.

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The Ion has announced its latest startup-focused program. MediaTech Venture's Houston startup incubator is launching next month. Photo courtesy of the Ion

New Houston incubator launches to support media tech innovation

ready to grow

Houston has a new incoming incubator program for innovators within the media technology space.

The Ion announced a new partnership with MediaTech Ventures, an Austin-based global media industry venture development company, that will bring the MediaTech incubator program to Houston. Applications are open now, and the first cohort will kick off the program in January.

“Modern media has to continually evolve and adapt to new market channels, and with each platform comes the opportunity for innovation to leverage what is possible. It’s why Houston continues to build its market and resources for media technology entrepreneurs and startups looking to make an impact in this constantly evolving space,” says Jan E. Odegard, executive director of the Ion, in a news release.

“We’re thrilled to partner with MediaTech Ventures to further bolster the startups that are an integral part of our innovation community," he continues.

The 12-week program will help early-stage companies tackle marketing, development, and production with education and mentorship with MediaTech Ventures' startup curriculum and platform. The Ion will house the initiative and startups will have access to the hub for programming and networking.

“Ion is the perfect home for our incubator program,” says Josh Sutton, Houston Program Manager at MediaTech Ventures, in the release. “Our goal is to not only tap into the Ion’s valuable innovation ecosystem both within its four walls and beyond it, but to catalyze the development of media technologies and offer more resources for entrepreneurs looking to advance modern media.”

Founded in 2016 to advance the media technology economy, MediaTech Ventures focuses on "unifying innovation with capital, and validating and scaling technology-enabled media startups," per the news release. The program's startups have raised over $10 million following the completion of the curriculum.

An info session is taking place on December 5 at Second Draught in the Ion, and interested applicants can meet, ask questions, and learn more about the program.

The Ion will house a new innovation hub focused on the future of medicine. Image courtesy of The Ion

Houston Methodist to open health innovation center in the Ion

coming soon

The Houston Methodist healthcare system has teamed up with the Ion innovation hub to open a health care innovation center.

The 1,200-square-foot tech hub is expected to open later this year. It initially will be geared toward activities like entrepreneurial programming, networking, mentoring, and pitching.

The space will be modeled after Houston Methodist’s Center for Innovation Technology Hub, which opened in 2020. In fact, the new hub will be a smaller “twin” of the existing hub, according to a news release.

Jan Odegard, executive director of the Ion, says the collaboration with Houston Methodist “will advance the Ion’s ability to support entrepreneurs and innovators that are already at the Ion as we embark on a new focus in health care innovation.”

Amid the rise of artificial intelligence and other tech advancements, along with the health care sector’s continuing drive to cut costs, one forecast indicates the value of the global market for digital health care will jump from $216.4 billion in 2022 to $441 billion by 2026. That would represent an increase of 104 percent.

Houston Methodist is the Ion’s first health care partner. The Ion already has partnerships in the aerospace and energy sectors.

“We are advancing the evolution of the hospital’s role in health care through digital transformation,” said Michelle Stansbury, vice president of innovation and IT applications at Houston Methodist. “Having a footprint at the Ion will not only provide the Ion’s network and Houston community with a window into what we are doing for patients, consumers and providers, but also gives The Ion community and rising innovators an opportunity to bring its own ingenuity and ideas to life with ours.”

Houston Methodist operates eight hospitals in the Houston area.

The 266,000-square-foot Ion anchors a 16-acre innovation district in Midtown. Rice Management Co. developed the district on behalf of Rice University.

“By enhancing opportunities for our network of academics, businesses, entrepreneurs, and innovators to collaborate across the Ion District and globally, we’re creating a more resilient future economy for our region,” says Bryson Grover, investment manager of real estate at Rice Management.

The space will be modeled after Houston Methodist’s Center for Innovation Technology Hub, which opened in 2020. Natalie Harms/InnovationMap

The Ion, NASA, and Rice University have teamed up to create new programming and collaboration within space innovation in Houston. Photo courtesy of The Ion

New strategic partnership sets out to bolster Houston's space economy

rocket fueled collaboration

The Ion innovation district and NASA’s Johnson Space Center are setting up a pipeline for Houston-area entrepreneurs to share ideas and intellectual property with the space agency.

The Ion and NASA are collaborating with Rice University on the new project, which is aimed at creating events, programming, and initiatives to promote the aerospace sector and the use of NASA technologies in the broader economy.

Vanessa Wyche, director of Johnson Space Center, says in a news release that the alliance will “help NASA solve challenges, develop spinoff technologies, grow minority entrepreneurs, and accelerate innovative and tech-forward solutions in Houston.”

Innovations developed through the new project will propel commercialization of space, Wyche says.

Much of the focus of the new alliance will be on minority-owned businesses, as well as aerospace and tech entrepreneurs. The Ion’s Aerospace Innovation Accelerator for Minority Business Enterprises will play a part in this strategy.

As part of the new collaboration, NASA and the Ion will open an application process for interested startups and entrepreneurs in the fall of 2022. The selected applicants will participate in programming through mid-2023.

“NASA’s Johnson Space Center has led the U.S. and the world on an ongoing journey of human exploration, and the Ion is here to accelerate tomorrow’s space endeavors. … Together we will safeguard Houston’s title as ‘Space City’ and advance the global space industry for future missions,” says Jan Odegard, executive director of the Ion.

Houston stands to grab a sizable share of the continuously growing space economy.

A Space Foundation report shows the value of the global space economy rose to $447 billion in 2020, up 4.4 percent from $428 billion in 2019. Morgan Stanley estimates the global space economy could generate revenue of $1 trillion or more by 2040, with satellite broadband representing nearly 40 percent of the sector.

Meanwhile, a report from the U.S. Bureau of Economic Analysis indicates the U.S. space economy accounted for $125.9 billion of price-adjusted GDP in 2019.

In Texas, the annual GDP of the space economy is estimated at $11.7 billion. The Perryman Group, a Waco-based economic analysis firm, forecasts this figure could soar to more than $27.3 billion in 2030 and nearly $57.6 billion in 2040.

The Perryman Group says the Texas space economy is expected to expand about 120 percent faster than the U.S. space economy, with the state’s portion of this economy potentially approaching 15 percent by 2040.

“Texas already plays an important role in space exploration and related industries,” the firm says in a report. “With a major public-sector presence, large and growing private-sector initiatives, and aggressive development efforts, the state is likely to significantly increase its share of the [space economy].”

The Ion Prototyping Lab is now open and will be powered by TXRX. Photo by Natalie Harms/InnovationMap

Ion Houston opens unique prototyping lab, names TXRX as partner

new to hou

Midtown Houston's innovation hub has unveiled its latest building feature and named its operation partner for the space.

The Ion opened its The Ion Prototyping Lab with the announcement that Houston nonprofit TXRX Labs will be the operator of the lab. The IPL’s 6,500 square-foot space will include access to tools — such as laser cutters, CNC mills and lathes, electronics assembly equipment, and 3D printers — as well as programming, training, and support.

“The Houston community’s growing need for these services has led to our growth from a small community organization to a partnership with Houston’s leading center for innovation, The Ion,” says Roland von Kurnatowski, president of TXRX Labs, in a news release. “With our presence at The Ion and in its Prototyping Lab, we are able to join together innovative ideas and technology to create a social and collaborative space to support tomorrow’s entrepreneurs' needs and challenges.”

Founded in 2008 and based in the East End Maker Hub, TXRX Labs provides community-focused engineering and fabrication services and job training programs. The nonprofit's goal is to make Houston a major 21st-century manufacturing hub.

The new space within the 266,000 square-foot innovation hub was designed by Gensler and is "the largest open corporate and startup-aligned prototyping space in Houston," according to the release.

“As part of Gensler’s contributions to the development of The Ion, we strategically designed the Prototyping Lab to function as a dedicated space for innovators and entrepreneurs to collaborate,” says Vincent Flickinger, senior associate and design director of Gensler Houston. “The Ion Prototyping Lab is equipped with tools for prototyping robotics and other energy focused innovations and cultivates an entirely new way of doing business in a reimagined, historic building and with one of Houston’s fastest-growing innovators, TXRX. We look forward to introducing the IPL’s offerings to the public.”

The IPL is the latest opening for The Ion. Last summer, the hub, which is opened and managed by Rice Management Company, opened its coworking space. The next openings to expect are an investor studio and several restaurant concepts, including Late August, The Lymbar, and more. Common Bond On-The-Go, located on the main floor of the Ion, opened this week too.

“With its close proximity to Houston’s Central Business District and The Texas Medical Center, The Ion is thrilled to provide the Houston tech community the Prototyping Lab operated by TXRX as an essential resource for businesses,” says Jan E. Odegard, executive director of The Ion, in the release. “The Ion serves as a driver and convener of activity, while TXRX's successful model of hands-on training and technological innovation is being leveraged to jumpstart the activity of entrepreneurs, corporations, and researchers. You think it, we make it.”

Members will have daily access to the IPL from 9 am to 5 pm. The cost of the membership has not been announced, but IPL will offer grant opportunities, per the release. All members must first complete a safety and skills training course.

The Ion has officially opened its coworking space on the second floor of the Midtown building. Rendering courtesy of Common Desk

The Ion Houston announces opening of its coworking space

calling all coworkers

The Ion Houston's coworking space — roughly four times the size of a typical Walgreens drugstore — opened this week ready to welcome its pre-leased tenants and potential coworkers alike.

The coworking space, Common Desk, occupies 58,400 square feet on the second floor of The Ion. That represents about one-fifth of the 266,000-square-foot Ion complex.

Amenities at Common Desk include craft coffee from local purveyors, unlimited conference room bookings, access to all shared areas on the second floor, private chat booths, full kitchens, and break areas.

Other tenants at The Ion include Chevron Technology Ventures and Microsoft. The Ion opened earlier this year, occupying the former Sears store in Midtown following a $100 million conversion. It's part of the 16-acre Innovation District, being developed by Rice University and the City of Houston.

"We can't wait for our new Common Desk tenants and members across their network to experience the magic that's being made here," Jan Odegard, executive director of The Ion, says in a news release. "Just as The Ion, alongside developer Rice Management Company, set out to build an innovation community and hub different from anything the nation has ever seen, Common Desk set out to build its biggest and most innovative space yet."

Dallas-based Common Desk specializes in flexible office space. Its location at The Ion is the company's largest flex office space to date.

"Common Desk has joined the ranks of some of the nation's top companies to cultivate an authentic, game-changing community destined to transform Houston's innovation ecoscape," says Dawson Williams, head of growth and partnerships at Common Desk.

Members of the Common Desk location at The Ion also can use the company's three other coworking spaces in Houston, as well as it locations in Austin, Dallas-Fort Worth, and North Carolina.

Common Desk's coworking space has several options for leasing. Photos courtesy of Common Desk

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6 female-founded startups shaping the Houston innovation ecosystem

meet the finalists

Female-founded businesses reached a new milestone last year. According to payroll company Gusto, female founders launched 49 percent of new businesses in 2024, reaching near parity with male-founded businesses for the first time.

And though they still face challenges, with access to VC funding at the top of the list, those women-led companies are driving major impact in the startup and innovation ecosystem.

The fifth-annual Houston Innovation Awards will honor six women-led startups that are shaping Houston innovation in our Female-founded Businesses category.

The finalists for the 2025 award, selected by our esteemed panel of judges, range from a company developing natural carbon-free fuel to another launching at-home sleep apnea technology.

Read more about these innovative startups and the visionary female founders behind them below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled at our live awards ceremony.

Tickets are now on sale for this exclusive event celebrating all things Houston innovation.

Anning Corporation

Clean energy company Anning Corporation is working to develop geologic hydrogen, a natural carbon-free fuel, using its proprietary stimulation approaches and advanced exploration modeling. The company said that geologic hydrogen has the potential to be the lowest-cost source of reliable baseload electricity in the U.S.

The company was founded by CEO Sophie Broun in 2024 and is a member of Greentown Labs. Last month, it also announced that it was chosen to participate in Breakthrough Energy’s prestigious Fellows Program. Anning raised a pre-seed round this year and is currently raising a $6 million seed round.

Bairitone Health

Bairitone Health is bringing anatomy imaging for sleep apnea to the home environment. The company's platform maps users' anatomy during natural sleep using a facial patch to determine the root cause of airway obstruction. It then offers effective therapies for each patient. The system is currently in the research and development phase and is being used in clinical trials and studies.

The company was founded in 2022 in the Texas Medical Center's Biodesign program by CEO Meagan Pitcher, CTO Onur Kilic and chief medical officer Britt Cross. It was a member of Activate Houston's inaugural cohort and has participated in numerous accelerators and incubators. It raised a pre-seed round last year of $435,000.

Brain Haven

Founded at the University of Houston, Brain Haven is developing neuroscience-based, clinically validated protocols that use sensory stimulation through smell and sound to offer a natural and non-invasive way to activate the brain and preserve neuroplasticity. The company aims to deliver an accessible and affordable way for the aging population to preserve memory, delay cognitive decline and improve quality of life.

The company was co-founded by Gail Aflalo, a graduate student in the University of Houston College of Optometry, and Jokūbas Žiburkus, an associate professor in the department of biology and biochemistry at UH. It was selected to participate in the 2024 Innov8 Cohort, where it won the cohort's Startup Pitch Day, and was included in Class 13 of UH RED Labs. Brain Haven was awarded $70,000 in seed funding from UH in June 2025 to support a year-long research initiative in adults aged 50 and above.

FlowCare

Sugar Land-based FlowCare is developing a period health platform that integrates smart dispensers, education and healthcare into one system to make free, high-quality organic period products more accessible.

The company was founded by CEO Tanu Jain, a registered nurse and product management executive, in 2024. It participated in the TiE Women Program and the Houston Community College Business Plan Competition, placing in the top five in both pitch competitions.

March Biosciences

Houston cell therapy company March Biosciences aims to treat unaddressed challenging cancers, with its MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma, currently in Phase 2 clinical trials.

The company was founded in 2021 by CEO Sarah Hein, Max Mamonkin and Malcolm Brenner and was born out of the TMC Accelerator for Cancer Therapeutics. The company completed a $29.6 million series A last year and also raised a $4.2 million seed round.

TrialClinIQ

Houston-based TrialClinIQ is an AI-powered clinical trial recruitment platform that helps identify, qualify and enroll eligible patients in appropriate trials faster and more accurately.

The company was founded in 2025 by CEO Jontel Pierce and Janette Obi.

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The Houston Innovation Awards program is sponsored by Houston Community College, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Former NASA astronaut, official joins Venus Aerospace board

astronaut appointment

Retired Air Force colonel and former NASA astronaut Pamela Melroy, who previously served as deputy administrator of NASA, recently joined the board of directors at Houston-based Venus Aerospace.

Venus Aerospace, a startup founded in 2020, develops rocket engine technology, including rotating rocket detonation engines for hypersonic flights. These engines promise higher power, greater fuel efficiency and lower emissions than conventional rocket engines or jet engines, according to the Interesting Engineering website. The global rocket propulsion market is expected to grow from $9.5 billion in 2025 to $29.9 billion by 2034, according to a forecast by ResearchAndMarkets.com.

“Advanced rocket propulsion has been of interest to me for over a decade, and Venus Aerospace’s recent achievements in demonstrating the stability of rotating detonation rocket engines represent a significant development,” says Melroy, who left NASA earlier this year and is now a self-employed consultant living in Arlington, Virginia.

Melroy, a member of the United States Astronaut Hall of Fame, has built an illustrious career in the aerospace sector. Aside from being a NASA official, she was:

  • One of only two female astronauts to command a space shuttle mission
  • Deputy program manager of Orion space exploration initiatives at aerospace and defense contractor Lockheed Martin
  • Senior technical adviser and director of field operations for the Federal Aviation Administration’s Office of Commercial Space Transportation, where she came up with the first safety guidelines for commercial human spaceflight
  • Deputy director of the Tactical Technology Office at the Defense Advanced Research Projects Agency (DARPA).
  • An adviser for the establishment of the Australian Space Agency

Venus Aerospace said in a news release that as a leader at three federal agencies, “Melroy shaped America’s strategy in space, accelerated commercial space partnerships, and deepened space exploration.”

Sassie Duggleby, co-founder and CEO of Venus Aerospace, called Melroy “a preeminent leader in the world of aerospace.”

In May, Venus Aerospace completed the inaugural test flight of its rotating detonation rocket engine. The startup, whose headquarters is at the Houston Spaceport, says it’s the only company in the world that has manufactured a flight-proven, high-thrust rotating detonation rocket engine.

On the horizon for Venus Aerospace is production of Stargazer M4, a high-speed aircraft capable of two-hour global travel.

Venus Aerospace’s investors include Airbus Ventures, America’s Frontier Fund, Trousdale Ventures, and Prime Movers Lab. The startup also gets support from the Air Force Research Laboratory (AFWERX), the Air Force, NASA and DARPA.

Jordan Blashek, co-founder and managing partner of America’s Frontier Fund, which backs startups creating breakthrough technologies, said his firm’s investment in Venus Aerospace “underscores our focus on supporting American companies that are revolutionizing industries of the future.”

“With recent hypersonic advancements from China and Russia, safeguarding American innovation and securing our industrial base has never been more urgent,” Blashek added. “Venus Aerospace is poised to redefine hypersonic flight and ensure America’s continued leadership in aerospace innovation.”

Since its founding, Venus Aerospace has raised $78.3 million in investments, according to PitchBook data.

Texas-based energy startup raises $1 billion on heels of Houston expansion

Powering Up

Austin-based startup Base Power, which offers battery-supported energy in the Houston area and other regions, has raised $1 billion in series C funding—making it one of the largest venture capital deals this year in the U.S.

VC firm Addition led the $1 billion round. All of Base Power’s existing major investors also participated, including Trust Ventures, Valor Equity Partners, Thrive Capital, Lightspeed Venture Partners, Andreessen Horowitz (a16z), Altimeter, StepStone Group, 137 Ventures, Terrain, Waybury Capital, and entrepreneur Elad Gil. New investors include Ribbit Capital, Google-backed CapitalG, Spark Capital, Bond, Lowercarbon Capital, Avenir Growth Capital, Glade Brook Capital Partners, Positive Sum and 1789 Capital Management.

Coupled with the new $1 billion round, Base Power has hauled in more than $1.27 billion in funding since it was founded in 2023.

Base Power supplies power to homeowners and the electric grid through a distributed storage network.

“The chance to reinvent our power system comes once in a generation,” Zach Dell, co-founder and CEO of Base Power, said in a news release. “The challenge ahead requires the best engineers and operators to solve it, and we’re scaling the team to make our abundant energy future a reality.”

Zach Dell is the son of Austin billionaire and Houston native Michael Dell, chairman and CEO of Round Rock-based Dell Technologies.

In less than two years, Base Power has developed more than 100 megawatt-hours of battery-enabled storage capacity. One megawatt-hour represents one hour of energy use at a rate of one million watts.

Base Power recently expanded its service to the city of Houston. It already was delivering energy to several other communities in the Houston area. To serve the Houston region, the startup has opened an office in Katy.

The startup also serves the Dallas-Fort Worth and Austin markets. At some point, Base Power plans to launch a nationwide expansion.

To meet current and future demand, Base Power is building its first energy storage and power electronics factory at the former downtown Austin site of the Austin American-Statesman’s printing presses.

“We’re building domestic manufacturing capacity for fixing the grid,” Justin Lopas, co-founder and chief operating officer of Base Power, added in the release. “The only way to add capacity to the grid is [by] physically deploying hardware, and we need to make that here in the U.S. ... This factory in Austin is our first, and we’re already planning for our second.”

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This article originally appeared on EnergyCapitalHTX.com.

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