The Ion named three corporate partners ahead of its annual innovation-focused festival. Photo courtesy of the Ion

Houston’s Ion innovation hub has recruited three heavyweight corporate partners, the hub announced earlier this week.

The new partners are:

  • Houston-based energy company Occidental (known as Oxy).
  • United Airlines Ventures, the sustainability-focused VC arm of Chicago-based United Airlines. United operates a major hub in Houston.
  • Australia-based Woodside Energy, which maintains an office in Houston.

Oxy, United Airlines Ventures, and Woodside will share their expertise in support of Ion’s mission to transform Houston into a global innovation ecosystem, according to an Ion news release. In addition, they will participate in Ion programming and network with Ion affiliates. Executives from all three of the new partners will serve on the Ion Leadership Advisory Roundtable.

“Welcoming our newest partners into Ion’s ecosystem is a further testament to our momentum in the aerospace and energy transition,” says Jan Odegard, who became executive director of the Ion in 2021 after a year of holding the interim position. “Each organization brings their own culture of innovation that aligns with what we are doing at the Ion.”

Michael Leskinen, president of United Airlines Ventures, says the VC firm believes “the Ion will be the epicenter for Houston’s rapidly growing innovation community — a one-stop shop to share ideas, foster startups, and to develop relationships with Houston’s brightest companies and academia.”

Oxy, United Airlines Ventures, and Woodside join Ion corporate partners such as:

  • Aramco Americas
  • Baker Botts
  • BP
  • Chevron
  • ExxonMobil
  • Global Custom Commerce
  • Intel
  • Microsoft
  • Transocean

The Ion announced the new corporate partners in advance of the second annual Ion Activation Festival, set for May 17-19. The Ion and Rice Management Co. host the festival, which shines a spotlight on entrepreneurship and innovation in Houston.

Activities will take place primarily at the Ion’s 16-acre campus. To register for the festival, visit the Ion’s website.

The inaugural festival, held in 2022, drew more than 2,500 attendees.

The Ion has announced its latest startup-focused program. MediaTech Venture's Houston startup incubator is launching next month. Photo courtesy of the Ion

New Houston incubator launches to support media tech innovation

ready to grow

Houston has a new incoming incubator program for innovators within the media technology space.

The Ion announced a new partnership with MediaTech Ventures, an Austin-based global media industry venture development company, that will bring the MediaTech incubator program to Houston. Applications are open now, and the first cohort will kick off the program in January.

“Modern media has to continually evolve and adapt to new market channels, and with each platform comes the opportunity for innovation to leverage what is possible. It’s why Houston continues to build its market and resources for media technology entrepreneurs and startups looking to make an impact in this constantly evolving space,” says Jan E. Odegard, executive director of the Ion, in a news release.

“We’re thrilled to partner with MediaTech Ventures to further bolster the startups that are an integral part of our innovation community," he continues.

The 12-week program will help early-stage companies tackle marketing, development, and production with education and mentorship with MediaTech Ventures' startup curriculum and platform. The Ion will house the initiative and startups will have access to the hub for programming and networking.

“Ion is the perfect home for our incubator program,” says Josh Sutton, Houston Program Manager at MediaTech Ventures, in the release. “Our goal is to not only tap into the Ion’s valuable innovation ecosystem both within its four walls and beyond it, but to catalyze the development of media technologies and offer more resources for entrepreneurs looking to advance modern media.”

Founded in 2016 to advance the media technology economy, MediaTech Ventures focuses on "unifying innovation with capital, and validating and scaling technology-enabled media startups," per the news release. The program's startups have raised over $10 million following the completion of the curriculum.

An info session is taking place on December 5 at Second Draught in the Ion, and interested applicants can meet, ask questions, and learn more about the program.

The Ion will house a new innovation hub focused on the future of medicine. Image courtesy of The Ion

Houston Methodist to open health innovation center in the Ion

coming soon

The Houston Methodist healthcare system has teamed up with the Ion innovation hub to open a health care innovation center.

The 1,200-square-foot tech hub is expected to open later this year. It initially will be geared toward activities like entrepreneurial programming, networking, mentoring, and pitching.

The space will be modeled after Houston Methodist’s Center for Innovation Technology Hub, which opened in 2020. In fact, the new hub will be a smaller “twin” of the existing hub, according to a news release.

Jan Odegard, executive director of the Ion, says the collaboration with Houston Methodist “will advance the Ion’s ability to support entrepreneurs and innovators that are already at the Ion as we embark on a new focus in health care innovation.”

Amid the rise of artificial intelligence and other tech advancements, along with the health care sector’s continuing drive to cut costs, one forecast indicates the value of the global market for digital health care will jump from $216.4 billion in 2022 to $441 billion by 2026. That would represent an increase of 104 percent.

Houston Methodist is the Ion’s first health care partner. The Ion already has partnerships in the aerospace and energy sectors.

“We are advancing the evolution of the hospital’s role in health care through digital transformation,” said Michelle Stansbury, vice president of innovation and IT applications at Houston Methodist. “Having a footprint at the Ion will not only provide the Ion’s network and Houston community with a window into what we are doing for patients, consumers and providers, but also gives The Ion community and rising innovators an opportunity to bring its own ingenuity and ideas to life with ours.”

Houston Methodist operates eight hospitals in the Houston area.

The 266,000-square-foot Ion anchors a 16-acre innovation district in Midtown. Rice Management Co. developed the district on behalf of Rice University.

“By enhancing opportunities for our network of academics, businesses, entrepreneurs, and innovators to collaborate across the Ion District and globally, we’re creating a more resilient future economy for our region,” says Bryson Grover, investment manager of real estate at Rice Management.

The space will be modeled after Houston Methodist’s Center for Innovation Technology Hub, which opened in 2020. Natalie Harms/InnovationMap

The Ion, NASA, and Rice University have teamed up to create new programming and collaboration within space innovation in Houston. Photo courtesy of The Ion

New strategic partnership sets out to bolster Houston's space economy

rocket fueled collaboration

The Ion innovation district and NASA’s Johnson Space Center are setting up a pipeline for Houston-area entrepreneurs to share ideas and intellectual property with the space agency.

The Ion and NASA are collaborating with Rice University on the new project, which is aimed at creating events, programming, and initiatives to promote the aerospace sector and the use of NASA technologies in the broader economy.

Vanessa Wyche, director of Johnson Space Center, says in a news release that the alliance will “help NASA solve challenges, develop spinoff technologies, grow minority entrepreneurs, and accelerate innovative and tech-forward solutions in Houston.”

Innovations developed through the new project will propel commercialization of space, Wyche says.

Much of the focus of the new alliance will be on minority-owned businesses, as well as aerospace and tech entrepreneurs. The Ion’s Aerospace Innovation Accelerator for Minority Business Enterprises will play a part in this strategy.

As part of the new collaboration, NASA and the Ion will open an application process for interested startups and entrepreneurs in the fall of 2022. The selected applicants will participate in programming through mid-2023.

“NASA’s Johnson Space Center has led the U.S. and the world on an ongoing journey of human exploration, and the Ion is here to accelerate tomorrow’s space endeavors. … Together we will safeguard Houston’s title as ‘Space City’ and advance the global space industry for future missions,” says Jan Odegard, executive director of the Ion.

Houston stands to grab a sizable share of the continuously growing space economy.

A Space Foundation report shows the value of the global space economy rose to $447 billion in 2020, up 4.4 percent from $428 billion in 2019. Morgan Stanley estimates the global space economy could generate revenue of $1 trillion or more by 2040, with satellite broadband representing nearly 40 percent of the sector.

Meanwhile, a report from the U.S. Bureau of Economic Analysis indicates the U.S. space economy accounted for $125.9 billion of price-adjusted GDP in 2019.

In Texas, the annual GDP of the space economy is estimated at $11.7 billion. The Perryman Group, a Waco-based economic analysis firm, forecasts this figure could soar to more than $27.3 billion in 2030 and nearly $57.6 billion in 2040.

The Perryman Group says the Texas space economy is expected to expand about 120 percent faster than the U.S. space economy, with the state’s portion of this economy potentially approaching 15 percent by 2040.

“Texas already plays an important role in space exploration and related industries,” the firm says in a report. “With a major public-sector presence, large and growing private-sector initiatives, and aggressive development efforts, the state is likely to significantly increase its share of the [space economy].”

The Ion Prototyping Lab is now open and will be powered by TXRX. Photo by Natalie Harms/InnovationMap

Ion Houston opens unique prototyping lab, names TXRX as partner

new to hou

Midtown Houston's innovation hub has unveiled its latest building feature and named its operation partner for the space.

The Ion opened its The Ion Prototyping Lab with the announcement that Houston nonprofit TXRX Labs will be the operator of the lab. The IPL’s 6,500 square-foot space will include access to tools — such as laser cutters, CNC mills and lathes, electronics assembly equipment, and 3D printers — as well as programming, training, and support.

“The Houston community’s growing need for these services has led to our growth from a small community organization to a partnership with Houston’s leading center for innovation, The Ion,” says Roland von Kurnatowski, president of TXRX Labs, in a news release. “With our presence at The Ion and in its Prototyping Lab, we are able to join together innovative ideas and technology to create a social and collaborative space to support tomorrow’s entrepreneurs' needs and challenges.”

Founded in 2008 and based in the East End Maker Hub, TXRX Labs provides community-focused engineering and fabrication services and job training programs. The nonprofit's goal is to make Houston a major 21st-century manufacturing hub.

The new space within the 266,000 square-foot innovation hub was designed by Gensler and is "the largest open corporate and startup-aligned prototyping space in Houston," according to the release.

“As part of Gensler’s contributions to the development of The Ion, we strategically designed the Prototyping Lab to function as a dedicated space for innovators and entrepreneurs to collaborate,” says Vincent Flickinger, senior associate and design director of Gensler Houston. “The Ion Prototyping Lab is equipped with tools for prototyping robotics and other energy focused innovations and cultivates an entirely new way of doing business in a reimagined, historic building and with one of Houston’s fastest-growing innovators, TXRX. We look forward to introducing the IPL’s offerings to the public.”

The IPL is the latest opening for The Ion. Last summer, the hub, which is opened and managed by Rice Management Company, opened its coworking space. The next openings to expect are an investor studio and several restaurant concepts, including Late August, The Lymbar, and more. Common Bond On-The-Go, located on the main floor of the Ion, opened this week too.

“With its close proximity to Houston’s Central Business District and The Texas Medical Center, The Ion is thrilled to provide the Houston tech community the Prototyping Lab operated by TXRX as an essential resource for businesses,” says Jan E. Odegard, executive director of The Ion, in the release. “The Ion serves as a driver and convener of activity, while TXRX's successful model of hands-on training and technological innovation is being leveraged to jumpstart the activity of entrepreneurs, corporations, and researchers. You think it, we make it.”

Members will have daily access to the IPL from 9 am to 5 pm. The cost of the membership has not been announced, but IPL will offer grant opportunities, per the release. All members must first complete a safety and skills training course.

The Ion has officially opened its coworking space on the second floor of the Midtown building. Rendering courtesy of Common Desk

The Ion Houston announces opening of its coworking space

calling all coworkers

The Ion Houston's coworking space — roughly four times the size of a typical Walgreens drugstore — opened this week ready to welcome its pre-leased tenants and potential coworkers alike.

The coworking space, Common Desk, occupies 58,400 square feet on the second floor of The Ion. That represents about one-fifth of the 266,000-square-foot Ion complex.

Amenities at Common Desk include craft coffee from local purveyors, unlimited conference room bookings, access to all shared areas on the second floor, private chat booths, full kitchens, and break areas.

Other tenants at The Ion include Chevron Technology Ventures and Microsoft. The Ion opened earlier this year, occupying the former Sears store in Midtown following a $100 million conversion. It's part of the 16-acre Innovation District, being developed by Rice University and the City of Houston.

"We can't wait for our new Common Desk tenants and members across their network to experience the magic that's being made here," Jan Odegard, executive director of The Ion, says in a news release. "Just as The Ion, alongside developer Rice Management Company, set out to build an innovation community and hub different from anything the nation has ever seen, Common Desk set out to build its biggest and most innovative space yet."

Dallas-based Common Desk specializes in flexible office space. Its location at The Ion is the company's largest flex office space to date.

"Common Desk has joined the ranks of some of the nation's top companies to cultivate an authentic, game-changing community destined to transform Houston's innovation ecoscape," says Dawson Williams, head of growth and partnerships at Common Desk.

Members of the Common Desk location at The Ion also can use the company's three other coworking spaces in Houston, as well as it locations in Austin, Dallas-Fort Worth, and North Carolina.

Common Desk's coworking space has several options for leasing. Photos courtesy of Common Desk

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Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.