This week's roundup of Houston innovators includes Aaron Knape of sEATz, Ivery Boston III of Houston Exponential, and Jesse Martinez of the LatinX Startup Alliance. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from sportstech to startup-focused nonprofit work — recently making headlines in Houston innovation.

Aaron Knape, CEO and co-founder of sEATz

Aaron Knape joins the Houston Innovators Podcast to share how he's taking the sEATz platform into a new vertical. Photo courtesy of sEATz

Although sEATz was founded in 2018, Aaron Knape, CEO and co-founder, says it's only now that the company is really coming into its own as a startup ready to scale in a big way.

"I tell the team that we're kind of coming out of stealth mode — I know we're not in a true stealth mode, but we haven't spent a lot of money on sales and marketing," Knape says on this week's episode of the Houston Innovators Podcast. "Now it's time to start putting that emphasis on who we are, that we're here, and we're ready to take over."

Knape joins the show to discuss sEATz's expansion into health care and what's next for the growing company. Click here to read more and stream the podcast.

Ivery Boston III, director of inclusive innovation at Houston Exponential

Ivery Boston III joins HX to lead inclusive efforts. Photo via LinkedIn

Houston Exponential made a new hire to reflect on the city's diversity. Ivery Boston III is one week into his role as HX's director of inclusive innovation. He will be tasked with leading prototyping and testing new inclusive ideas and ways of operating, according to a news release from HX. He will also be responsible for creating opportunities for underrepresented founders to succeed in Houston.

Boston joins HX from Miami, where he led research, strategy, recruitment of high-growth startups, and impact reporting for the Miami Downtown Development Authority.

"I am excited to serve the Houston community as the director of inclusive innovation at Houston Exponential," says Boston in the release. "I'm a massive fan of HX's work advocating for, connecting, and raising the profile of the Houston innovation ecosystem while linking local founders to funding. It is a privilege to join this exemplary team and provide additional attention to underrepresented and under-encouraged founders within the city." Click here to read more.

Jesse Martinez, founder of the LatinX Startup Alliance

Jesse Martinez, founder of the LatinX Startup Alliance, joins InnovationMap for a Q&A on why he's relocating his nonprofit to Houston. Photo courtesy of LSA

Wheen Jesse Martinez was looking for startup support as a Latino founder, he couldn't find it. So, he took the initiative to make it himself and launched the LatinX Startup Alliance. The Houston native announced his plans to relocate his Silicon Valley nonprofit to The Ion next year.

He tells InnovationMap why he thinks Houston is the right market for LSA.

"We're on the ground floor. We're helping to build that foundation. It's not an afterthought. It's not something that now we're trying to go back and think of diversity," Martinez tells InnovationMap. "I think that's the beautiful thing about Houston and everyone that I've met is that it's been so diverse and inclusive. That spirit is already there. So, how do we just maximize that?" Click here to read the full Q&A.

Ivery Boston III joins HX to lead inclusive efforts. Photo via LinkedIn

Houston Exponential hires new exec to promote inclusive innovation

new to hou

Houston's considered one of the most diverse cities in the country, and Houston Exponential is focused on building an innovation ecosystem that's reflective of that.

The nonprofit organization announced a new hire that will lead this initiative. Ivery Boston III started this week as HX's director of inclusive innovation. He will be tasked with leading prototyping and testing new inclusive ideas and ways of operating, according to a news release from HX. He will also be responsible for creating opportunities for underrepresented founders to succeed in Houston.

"Other cities, in their dogged pursuit of being the next 'Silicon Valley,' followed the coastal playbook and weren't deliberate to support underserved entrepreneurs," says Serafina Lalany, executive director of Houston Exponential, in the release. "There is still much work to be done to address subtle and persistent forms of bias in the ways underrepresented founders access the resources, capital, and talent needed to thrive here in Houston. This move, for Houston Exponential and for the City of Houston, is part of an intentional strategy to foster a more inclusive, accessible ecosystem."

Boston joins HX from Miami, where he led research, strategy, recruitment of high-growth startups, and impact reporting for the Miami Downtown Development Authority.

"I am excited to serve the Houston community as the director of inclusive innovation at Houston Exponential," says Boston in the release. "I'm a massive fan of HX's work advocating for, connecting, and raising the profile of the Houston innovation ecosystem while linking local founders to funding. It is a privilege to join this exemplary team and provide additional attention to underrepresented and under-encouraged founders within the city."

Boston has also worked with Indeed.com, Zipcar, Sodexo, and other companies within market reporting. He attended Temple University.

"I look forward to rolling up my sleeves and ensuring that all Houstonians can see a viable path to entrepreneurship," he continues. "It's time to leverage Houston's diversity to bring in additional funding sources, create jobs, and use the profound local awareness of the world to launch businesses, services, and products that serve the global market."

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Texas universities develop innovative open-source platform for cell analysis

picture this

What do labs do when faced with large amounts of imaging data? Powerful cloud computing systems have long been the answer to that question, but a new riposte comes from SPACe.

That’s the name of a new open-source image analysis platform designed by researchers at Baylor College of Medicine, Texas A&M University and the University of Houston.

SPACe, or Swift Phenotypic Analysis of Cells, was created to be used on standard computers that even small labs can access, meaning cellular analysis using images produced through cell painting has a lower barrier to entry than ever before.

“The pharmaceutical industry has been accustomed to simplifying complex data into single metrics. This platform allows us to shift away from that approach and instead capture the full diversity of cellular responses, providing richer, more informative data that can reveal new avenues for drug development,” Michael Mancini, professor of molecular and cellular biology and director of the Gulf Coast Consortium Center for Advanced Microscopy and Image Informatics co-located at Baylor College of Medicine and TAMU Institute for Bioscience and Technology.

SPACe is not only accessible because of its less substantial computational needs. Because the platform is open-source, it’s available to anyone who needs it. And it can be used by academic and pharmaceutical researchers alike.

“The platform allows for the identification of non-toxic effects of drugs, such as alterations in cell shape or effects on specific organelles, which are often overlooked by traditional assays that focus largely on cell viability,” says Fabio Stossi, currently a senior scientist with St. Jude Children’s Research Hospital, the lead author who was at Baylor during the development of SPACe.

The platform is a better means than ever of analyzing thousands of individual cells through automated imaging platforms, thereby better capturing the variability of biological processes. Through that, SPACe allows scientists an enhanced understanding of the interactions between drugs and cells, and does it on standard computers, translating to scientists performing large-scale drug screenings with greater ease.

"This tool could be a game-changer in how we understand cellular biology and discover new drugs. By capturing the full complexity of cellular responses, we are opening new doors for drug discovery that go beyond toxicity,” says Stossi.

And the fact that it’s open-source allows scientists to access SPACe for free right now. Researchers interested in using the platform can access it through Github at github.com/dlabate/SPACe. This early version could already make waves in research, but the team also plans to continually improve their product with the help of collaborations with other institutions.

The Ion names new coworking partner for Houston innovation hub

Where to Work

Rice University subsidiary Rice Real Estate Co. has tapped coworking company Industrious as the new operator of the Ion’s 86,000-square-foot coworking space in Midtown. Industrious replaces WeWork-owned Common Desk in that role.

The Ion, owned by Rice Real Estate and located at 4201 Main St., is a 266,000-square-foot office building and innovation hub in the 16-acre Ion District.

Features of the coworking space include private suites and offices, dedicated desks, phone booths and conference rooms. In 2022, Common Desk said it was expanding the space by 28,000 square feet, bringing it to the current size.

“(Industrious’) unparalleled expertise in delivering quality, hospitality-driven workspaces complements our vision of creating a world-class ecosystem where entrepreneurs, corporations, and academia converge to drive innovation forward,” Ken Jett, president of Rice Real Estate, said in a statement.

Natalie Levine, senior manager of real estate at Industrious, says her company will work with Rice Real Estate “to continue to position the Ion as an invaluable contributor to the growth of Houston’s innovation community.”

Dallas-based commercial real estate services company CBRE said Jan. 14 that it had agreed to acquire Industrious in a deal valued at $400 million.

The Ion is Industrious’ second location in Houston. The company’s other local coworking space is at 1301 McKinney St.

Office tenants at the Ion include Occidental Petroleum, Fathom Fund, Activate, Carbon Clean, Microsoft and Chevron Technology Ventures.

Texas ranks among the 5 best states to start a business in 2025

Best for Biz

As one of the largest states in the U.S., it's no surprise Texas is big on business and entrepreneurship. Now the state is earning new praise among WalletHub's 2025 list of "Best & Worst States to Start a Business."

The Lone Star State claimed the No. 4 spot in the report's rankings, proving that Texas is in a much better business shape than it was last year when it earned No. 8 in WalletHub's annual report.

The study compared all 50 states across 25 metrics to determine the best places to start, grow, and find success with a new business. Factors that were considered include the number of startups per capita, job growth rates, financing accessibility measures, labor costs and corporate tax rates.

The three states to outperform Texas in the 2025 report are Florida (No. 1), Georgia (No. 2), and Utah (No. 3). Idaho rounded out the top five.

Across the study's three main categories, Texas performed the best in the "business environment" category, earning No. 1 nationally. This section compares the states based on five-year business survival rates, average business revenues growth and more.

Texas ranked No. 12 in the nationwide comparison of "access to resources" – which covers working age population growth, venture investment amounts per capita and other means – and earned a fair No. 34 in the report's "business costs" ranking.

But Texas can still do better with its business friendliness to reclaim a top-three overall ranking, which the state last earned in 2023.

WalletHub analyst Chip Lupo said in the report that it is imperative for potential new business owners to establish their enterprise in a place that can maximize their ability to succeed.

"Around half of all new businesses don’t survive five years, so the idea of becoming a business owner can be daunting, especially with the current high cost of living," Lupo said. "The best states have low corporate tax rates, strong economies, an abundance of reliable workers, easy access to financing and affordable real estate. On top of that, you’ll need to make sure you start in a place with an engaged customer base, if you’re operating locally."

Houston has also proven to be at the top of the destination list for entrepreneurs who are looking for their next venture.

The top 10 best states to start a new business in 2025 are:

  • No. 1 – Florida
  • No. 2 – Georgia
  • No. 3 – Utah
  • No. 4 – Texas
  • No. 5 – Idaho
  • No. 6 – Oklahoma
  • No. 7 – Nevada
  • No. 8 – Colorado
  • No. 9 – Arizona
  • No. 10 – Kentucky
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This story originally appeared on our sister site, CultureMap.