This week's roundup of Houston innovators includes Ayse McCracken of Ignite Healthcare Network, Paul Cherukuri of Rice University, and Oyetewa Oyerinde of Baylor College of Medicine. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health care to academia — recently making headlines in Houston innovation.

Ayse McCracken, founder of Ignite Healthcare Network

Ayse McCracken, founder of Ignite Healthcare Network, joins the Houston Innovators Podcast to discuss how she's growing her impact on female health tech founders. Photo via LinkedIn

With a decades-long career in health care, Ayse McCracken's most recent professional chapter has been laser focused on finding, supporting, and accelerating female-founded startups in health tech with her nonprofit, Ignite Healthcare Network.

Originally founded in 2017 as a pitch competition, Ignite has evolved to become an active and integral program for female health tech entrepreneurs. Ninety-one founders have graduated from Ignite and gone on to raise over $550 million in funding for their ventures. Currently, Ignite has 19 women in its 2023 cohort, which concludes November 9 with the annual Fire Pitch competition.

"Having an impact in the health care industry and finding solutions is important to me," McCracken says of her passion for Ignite on this week's episode of the Houston Innovators Podcast. "The second aspect of that is there are so many women in health care, and yet you don't see them in leadership roles." Read more.

Paul Cherukuri, vice president of innovation at Rice University

Paul Cherukuri, vice president of innovation at Rice University, has had a busy week. Photo via Rice.edu

If it's seemed like a lot has been happening on Rice University campus this month, it's because it has. This week, Paul Cherukuri, Rice’s vice president for innovation hosted an event announcing the university's Biotech Launch Pad, a new accelerator focused on commercializing health care innovations.

“The Biotech Launch Pad is the first in a series of Rice Moonshots that are hyper-focused on building a ‘speed and scale’ innovation ecosystem across Houston," Cherukuri says. "We at Rice are committed towards driving the Biotech Launch Pad in collaboration with our partners within the Texas Medical Center and the new Helix Park campus.” Read more.

The university also recently announced:

  • The Rice University Office of Innovation's newly established the One Small Step Grant program that will provide funding to faculty working on "promising projects with commercial potential." Read more.
  • The opening of the Ralph S. O’Connor Building for Engineering and Science, the university's largest core campus research facility. The 250,000-square-foot building is the new home for four key research areas at Rice: advanced materials, quantum science and computing, urban research and innovation, and the energy transition. The university aims for the space to foster collaboration and innovation between the disciplines. Read more.

Oyetewa Oyerinde, leader of the Skin of Color Clinic and assistant professor of dermatology at Baylor College of Medicine

The Skin of Color Clinic is devoted to the unique needs of patients of all ethnicities. Photo courtesy of BCM

All skin is created equal, but not all skin behaves the same. It’s with this in mind that Baylor Medicine Dermatology has announced the debut of its newest office.

The Skin of Color Clinic is located inside the Jamail Specialty Care Center and is devoted to the unique needs of patients of all ethnicities.

The leader of the Skin of Color Clinic is assistant professor of dermatology, Oyetewa Oyerinde. Dr. Oyerinde, a Howard University and University of Illinois at Chicago College of Medicine alum, completed her residency training at Harvard University, where she made it to the role of chief resident in her final year.

“I am excited to lead a clinic that addresses skin issues commonly found in underserved populations,” Oyerinde says in a news release. “I want people in Houston to know that there is a place where an expert will know how to care for their specific needs.” Read more.

Ignite Healthcare Network has hosted a pitch compeition for a few years now, but this is the first year for its mini-accelerator program. Courtesy of Ignite

Houston nonprofit launches accelerator program to give women-led startup a leg up within health care

The future is female

Within health care, female consumers make 80 percent of the buying power while women hold 65 percent of the workforce's jobs, according to a recent study. However, when you look at the C-suites in the industry, those percentages fall drastically, says Ayse McCracken.

"For as many women as there are involved in health care, it's not reflected in leadership," says McCracken, founder of Ignite Healthcare Network. "That's what brought us together."

Just 30 percent of health care C-suites are women — and only 13 percent have female CEOs, per the report by Oliver Wyman. Houston-based nonprofit Ignite is an organization comprised of over 150 of these rare female health care execs and focused on clearing a path for future female leaders in the industry.

McCracken founded the network in 2016, and her team established a "Shark Tank-style" pitch competition. After three years of the annual event seeing successes, Ignite is introducing its inaugural mini-accelerator program.

"As we saw this innovation economy and startup space begin to evolve in the city, it seemed that our contribution to this was that we could help incubate and find companies that had high likelihood of success," says McCracken.

Ignite and its partners identified 13 female-led companies from all around the world were selected from over 80 applications and now will go through a 10-week program called the Customer-Partner Program. Each company is paired with a partner and potential customer — from Memorial Hermann and Texas Children's Hospital to Humana and Gallagher.

Here are the participating female-led startups:

  • iTreatMD from San Francisco
  • BabyNoggin (by Qidza) from San Francisco
  • Ria Health from San Francisco
  • Savonix from San Francisco
  • MotiSpark from Los Angeles
  • UpHold Health from Chicago
  • Sound Scouts from Sydney, Australia
  • Augment Therapy from Cleveland, Ohio
  • Oncora Medical Philadelphia
  • Materna Medical from Mountain View, California
  • Path Ex Inc Houston
  • PyrAmes Inc. from Cupertino, California
  • Spoke Health Denver

The Fire Pitch Competition will take place on October 17 at the Texas Medical Center's Innovation Institute. Hundreds of thousands of dollars in prizes is on the line for the 13 companies.

"This year's event is already receiving increased recognition from investors," says Ignite board member and event co-chair, Cheryl Stavins, in a release. "In addition to the top three finalists sharing awards that include entry into the TMCx Digital Health Accelerator, over $125,000 in professional services, and cash prizes of $10,000, Fire Pitch participants will be eligible for investment prizes."

The Texas Halo Fund will be awarding its $100,000 investment prize, called the Corona Award, along with a $50,000 prize from TMC Innovation Institute.

Beyond the new program, McCracken says she wants to expand Ignite's reach and capabilities for its members and startups — including new investment opportunities.

"I think what we're doing now is reaching out beyond Houston and looking at how we can continue to grow the opportunity to have an impact and help women-led companies and women in organizations," she says.

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Houston company wins AHA competition for pediatric heart valve design

winner, winner

Houston-based PolyVascular, which develops minimally invasive solutions for children with congenital heart disease, was named the overall winner of the American Heart Association’s annual Health Tech Competition earlier this month.

The company was founded in 2014 by Dr. Henri Justino and Daniel Harrington and was part of TMCi's 2017 medical device cohort. It is developing the first polymer-based transcatheter pulmonary valve designed specifically for young children, allowing for precise sizing and redilation as the child grows while also avoiding degradation. PolyVascular has completed preclinical studies and is working toward regulatory submissions, an early feasibility study and its first-in-human clinical trial thanks to a recent SBIR grant from the National Heart, Lung, and Blood Institute.

With the new AHA honor, PolyVascular will be invited to join the association’s Center for Health Technology & Innovation Innovators’ Network, which connects entrepreneurs, providers and researchers to share and advance innovation in cardiovascular and brain health.

“This is a tremendous honor for PolyVascular—we’re especially proud to bring hope to families and children living with congenital heart defects,” Justino said in a news release. “Our technology—a minimally invasive valve that can be expanded over time to grow with the child—has the potential to dramatically reduce the need for repeated open-heart surgeries.”

The Health Tech Competition is a live forum for health care innovators to present their digital solutions for treating or preventing cardiovascular diseases and stroke.

Finalists from around the world addressed heart failure, hypertension, congenital heart defects and other issues that exist in cardiovascular, brain and metabolic health. Solutions were evaluated on the criteria of validity, scientific rigor and impact.

The judges included Texas-based Dr. Eric D. Peterson, professor of medicine in the division of cardiology at UT Southwestern Medical Center, and Dr. Asif Ali, clinical associate professor of cardiovascular medicine at the University of Texas Medical School in Houston and director at Cena Research Institute.

According to the American Heart Association, nearly half of U.S. adults live with some form of cardiovascular disease or stroke.

“The American Heart Association plays a pivotal role in advancing innovative care pathways, and we’re excited that our solution aligns with its guidelines and mission,” Justino said in a news release. “It’s time these life-changing technologies reach the youngest patients, just as they already do for adults.”

EO Houston is where ambitious founders go to scale smarter

Don't Go It Alone

Scaling a business from early traction into true growth is one of the most exciting — and punishing — chapters of entrepreneurship. Houston founders know this better than most. Our city is built on ambition: fast-moving industries, talent from around the world, and opportunities that expand as large as the Texas sky.

But as many entrepreneurs eventually learn, scaling isn’t simply “more of what worked.” It requires new systems, new thinking, and often, a new version of the founder. Even the most capable founders eventually face decisions, pressures, and turning points that only other entrepreneurs can truly understand.

Entrepreneurs’ Organization, a global peer-to-peer network of more than 18,000 business owners across 220 chapters in 75+ countries, exists for exactly this stage. One of the largest chapters in the organization, EO Houston brings that global community to life locally, offering founders the connection, learning, and accountability needed to grow sustainably and to grow up as leaders.

A community where founders learn at the highest level
The real value of EO emerges in the lived experiences of other entrepreneurs. When Houston-area founders talk about the moments growth nearly broke their companies, a universal theme appears: you can’t do it alone.

EO Houston member Robert De Los Santos of Sky High Party Rentals learned this the hard way when rapid post-COVID growth made expansion feel limitless — until it wasn’t.

“After COVID, we doubled every year and assumed inventory was the limit. In 2023 we overbought, only to realize demand had peaked. That taught us a hard truth: growth in one city has ceilings. Expanding into Austin and Dallas — the Texas Triangle — gave us new markets to put our inventory to work while we figured out how to penetrate Houston better. The challenge shifted from a strategy of ‘buy more units for demand’ to learning how to tackle the challenges of ‘leading across cities.’”

Founders often enter EO exhausted from trying to maintain control as things grow more complex. Many discover, like Jarred King of Summit Firms, that scaling requires the difficult shift from doing everything to building the team that can.

“We grew quickly because of my network, relationships, and hustle… but I was doing all the work,” King says. “I realized at that point you have to delegate — not just busy work, but important decisions to your key team, as well as set up really effective SOPs.”

“The uncomfortable truth is that you are no longer the best person for most jobs in your company," agrees Darren Randle of Houston Tents & Events. "Your inability to delegate or hire people smarter than you in key leadership and management level roles will become the single biggest drag on the entire business. You have to accept that your original 'hustle' is now a scalability risk."

Making hard decisions, such as walking away from customers or contracts, can feel like less of a sting when you know others have also been faced with tough choices. Aaron Gillaspie of West U's My Salon Suite recalls, “You can’t be everything to everyone, it’s ok to say no, and just understand some customers aren’t the right fit. It’s a two way street and both must win.”

Perspective is perhaps the most important reality check that members find at EO.

“Bigger volume will not make problems go away — you just got to get used to walking the tightrope," says Roger Pombrol of Emerald Standard. "Develop a system for good balance and do not freak out. Scared is no way to live your life. It’s ok if you fall. Your family will still love you. Money is just money. Love is love. The world tries to make you conflate them, but don’t."

Actionable insights from entrepreneurs who’ve already scaled
Conversations like these are happening every month inside EO Forum Meeting. Each EO chapter is divided into several small Forums. These confidential, committed group of 7–10 entrepreneurs who meet to share the real five percent of what they’re experiencing. It’s not advice, but experience — shared candidly, respectfully, and with the kind of vulnerability that leads to breakthroughs.

What makes Forum so impactful is the honesty it draws out. Entrepreneurs are often surrounded by employees, partners, and even family members who rely on them for answers, but seldom do they have a group where vulnerability is not only welcomed, but expected.

Learning experiences that match your ambition
EO supports that growth far beyond peer groups. Through the organization’s global partnerships with institutions like Harvard, Oxford, and INSEAD, Houston members gain access to executive-level learning experiences designed specifically for entrepreneurs.

These programs help founders step out of the day-to-day and think strategically about competitive advantage, innovation, and organizational leadership. Paired with ongoing learning through EO Jumpstart, Nano Learning, and its global library of member-created content, founders stay informed, challenged, and ahead of emerging trends.

And through global communities — ranging from EO Women and EO Under 35 to industry-specific groups — Houston members tap into expertise that spans continents and sectors. Whether someone is navigating M&A, exploring international expansion, or integrating new technologies, the right perspectives are always within reach.

What truly distinguishes EO Houston, however, is its culture. Houston’s entrepreneurial landscape is uniquely diverse and resilient, filled with founders who are hungry to build, innovate, and elevate the city’s business community. EO Houston amplifies that spirit, creating relationships that are as supportive as they are strategic. Many members describe the chapter not simply as a network, but as a catalyst for becoming better leaders, better thinkers, and — just as importantly — better human beings.

Your next level starts here
For entrepreneurs who are ready to scale—beyond their first million, beyond their current comfort zone, and toward a future that requires sharper leadership and stronger community—EO Houston offers an unmatched platform. It is a place where ambitious founders grow faster, think bigger, and gain the confidence to take bold next steps.

If you’re ready to elevate your business and your leadership alongside people who understand the journey, EO Houston is ready to welcome you. Your next level starts with the peers who can help you reach it. Learn more and become a member here.

3 Houston companies land on Deloitte’s Technology Fast 500 list

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Three Houston companies have made this year’s Deloitte North America Technology Fast 500 list.

The report ranks the fastest-growing technology, media, telecommunications, life sciences, fintech, and energy tech companies in North America. The Houston companies to make the list, along with their revenue growth rates from 2021-2024, include:

  • No. 16 Action1 Corp., a provider of cybersecurity software. Growth rate: 7,265 percent
  • No. 92 Cart.com, a commerce and logistics platform. Growth rate: 1,053 percent
  • No. 312 Tellihealth, a remote health care platform. Growth rate: 244 percent

“Houston’s unique blend of entrepreneurial energy and innovation continues to strengthen the local business community, and I’m thrilled to see Houston companies honored on the 2025 Deloitte Technology Fast 500 list. Congratulations to all the winners,” said Melinda Yee, managing partner in Deloitte’s Houston office.

Action1 is no stranger to lists like the Deloitte Technology Fast 500. For instance, the company ranked first among software companies and 29th overall on this year’s Inc. 5000, a list of the country’s fastest-growing private companies. Its growth rate from 2021 to 2024 reached 7,188 percent.

Mike Walters, president and co-founder of Action1, said in August that the Inc. 5000 achievement “reflects the dedication of Action1’s global team, who continue to execute against an ambitious vision: a world where cyberattacks exploiting vulnerabilities are entirely prevented across all types of devices, operating systems, and applications.”

Atlanta-based Impericus, operator of an AI-powered platform that connects health care providers with pharmaceutical and life sciences companies, topped the Deloitte list with a 2021-24 growth rate of 29,738 percent.

“Our mission is to set the standard for ethical AI-powered physician connections to pharma resources, accelerating and expanding patient access to needed treatments,” said Dr. Osama Hashmi, a dermatologist who’s co-founder and CEO of Impiricus. “As we continue to innovate quickly, we remain committed to building ethical bridges across this vital ecosystem.”